JP5053485B2 - Chemical peeling sheet - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention is a chemical peeling technique applied to improving the skin quality with respect to rough skin and dryness, removing acne, removing wrinkles from the skin, or removing spots and dullness (pigmentation such as senile pigment spots). In particular, the present invention relates to a sheet for chemical peeling used for applying a chemical peeling agent to the skin of a subject when performing chemical peeling.
[0002]
BACKGROUND OF THE INVENTION
Recently, cosmetics containing a low concentration of chemical peeling agent such as α-hydroxyacid (AHA), which is effective in removing skin stains and stains in addition to improving skin condition, have been actively used. It is coming. In Europe and the United States, removal of wrinkles and stains has been established as one of the medical fields. In recent years, the need for such treatment has been widely recognized in Japan. Along with this, research from a medical point of view regarding such treatment has been widely conducted in Japan.
A skin treatment method using a peeling agent is generally called chemical peeling. Such a treatment called chemical peeling, for example, is applied to the skin as an aqueous solution of appropriate concentration with a peeling agent such as trichloroacetic acid (TCA), phenol, fruit acid (eg, α-hydroxyacid (AHA)). It is carried out by creating chemical burns (corrosion) or applying moderate irritation to the skin. In other words, the skin treatment is performed by applying the above-mentioned drug to the skin, mainly peeling off the skin's horny layer and a part of the epidermis, and promoting the regeneration of new cells of the skin by the function of activating the cells.
[0003]
In order to perform chemical peeling, it is necessary to apply a chemical peeling agent at an appropriate concentration to the skin. However, applying a chemical peeling agent directly to the skin of the subject is troublesome in terms of preparation and application work, and it is difficult to apply. It is easy to leave and uneven coating. In consideration of such points, it is conceivable that the chemical peeling agent can be easily applied to the skin by sticking a chemical peeling sheet made of a cloth pre-applied with the chemical peeling agent to the skin.
[0004]
By the way, chemical peeling is intended to regenerate the skin by applying a certain load to the skin, so if the concentration of the chemical peeling agent is high or the application time of the chemical peeling agent is long, inflammation may occur, Undesirable effects such as excessive denaturation of cells and proteins may occur in the skin. Whether the concentration of the chemical peeling agent and how to apply the chemical peeling sheet will give the best results depends on the experience of the treating physician and the results of preliminary tests. Although the prediction to a certain extent is possible, the reaction to the drug varies greatly from person to person, and the reaction that occurs depending on the physical condition of the subject changes every day.
[0005]
If chemical peeling causes undesirable effects on the subject's skin, such as frosting (whitening due to protein denaturation of the skin), rash, or redness, it is essential to stop treatment immediately, and in some cases, peeling It is necessary to apply other agents for neutralizing the agent to the skin.
However, in the case of an opaque sheet for chemical peeling, it is impossible to confirm the state of the skin due to the influence of the chemical peeling agent in a state where the sheet is attached to the skin. If the effect on the skin cannot be confirmed immediately, the judgment of treatment interruption when chemical peeling is performed excessively tends to be delayed.
In other words, in order to make the sheet for chemical peeling practical, not only has an advantage for the application work, but also treatment can be performed while confirming whether or not an unfavorable effect has occurred on the skin. It must be a thing. Only if this can be realized will it be possible to achieve its widespread use.
On the other hand, in performing chemical peeling, it is important to apply a chemical peeling agent evenly to each part of the skin to be treated.
When treatment is performed using a chemical peeling sheet, it is necessary to remove the chemical peeling sheet when frosting, rash, redness, inflammation, or the like occurs in a part of the skin. However, if the entire chemical peeling sheet is removed, the treatment for the portion where no inflammation or the like has occurred is also terminated at the same time. In such a case, since the process to this part becomes inadequate, it is difficult for the conventional chemical peeling sheet to perform an equal process for each part of the skin to be treated.
[0006]
[Problems to be solved by the invention]
An object of the present invention is to provide a practical sheet for chemical peeling.
That is, an object of the present invention is to provide a sheet for chemical peeling that has both the advantage of easy application work and the advantage of treating chemical peeling while confirming the properties of the skin.
In addition, when an unfavorable effect occurs on the skin, treatment can be interrupted and the neutralizing agent can be quickly applied to the part, and chemical peeling can be continued to other parts. It is a further object to provide a sheet for chemical peeling.
[0007]
[Means for Solving the Problems]
The sheet for chemical peeling according to the present invention for solving the above-mentioned problems is as follows.
That is, it comprises a film substrate having transparency, or a film substrate that is transparent from one surface side to the other surface side, and a chemical peeling agent applied to one surface of the film substrate. It is a sheet sheet for chemical peeling, which enables the state of the skin to be observed when it is applied to the skin.
According to such a sheet for chemical peeling, it is possible to always observe the properties of the skin through the film base material even during chemical peeling by attaching it to the skin. Therefore, if any unfavorable effect occurs on the skin, it can be detected early and the treatment can be interrupted or the neutralizing agent can be applied immediately, improving the safety of chemical peeling. Be able to.
It should be noted that the transparent part of the film substrate and the part through which the other surface side can be seen from one side must overlap with the part coated with the chemical peeling agent. Any predetermined range of the material may be used. Of course, it does not matter if the entire membrane substrate is transparent or the other surface side is transparent from one surface side.
[0008]
The membrane base material in the chemical peeling sheet of the present invention may be any material as long as the properties of the skin can be visually recognized through the chemical peeling sheet attached. It may be transparent or not completely transparent, but may be translucent enough to visually recognize the skin properties. Moreover, as long as a chemical peeling sheet is pasted and the skin properties can be visually recognized through the sheet, it may be composed of multiple layers instead of one layer. For example, it is also possible to constitute this membrane substrate from a layer for maintaining the shape of the membrane substrate and a layer for holding a chemical peeling agent. Further, the membrane base material may be a mesh-like material made of an opaque material as long as the skin property can be visually recognized in the attached state, or may be a multilayer material including such a mesh-like layer.
A predetermined adhesive force can be given to the one surface of the membrane substrate. And thereby, a membrane base material can be stuck and fixed to a subject's skin by itself. Other adhesive sheets or the like can be used when the membrane substrate is attached to the skin. However, if the membrane substrate alone can be fixed to the skin, it is convenient for use. In this case, the film substrate itself may have adhesiveness, or an adhesive may be applied to a predetermined portion of the one surface of the non-adhesive film substrate. The pressure-sensitive adhesive may be applied only to a part different from that where the chemical peeling agent is applied, or may be applied by mixing with the chemical peeling agent.
The film substrate can also have flexibility to follow the unevenness of the skin. By using a flexible film substrate, the chemical peeling agent can be sufficiently brought into contact with each part of the skin.
Here, when the membrane substrate has transparency, it can be formed of silicone. Silicone is a material having transparency, and its surface properties can be changed in many ways by processing methods, so it is convenient to use as a film substrate of the present invention. For example, one surface of silicone formed into a film is processed so as to have a certain viscosity, and the other surface is processed like a resin having a certain hardness, and one surface of the surface has a viscosity. When a chemical peeling agent is applied to the film, the membrane base material can be formed from a single layer, so that the structure of the chemical peeling sheet can be simplified.
[0009]
A part of the membrane substrate in the chemical peeling sheet of the present invention can be configured to be easily excised. In this way, when an undesirable effect on the skin can be confirmed during chemical peeling, a part of the membrane substrate corresponding to the position is immediately excised to minimize the effect on the skin. It will be possible to hold down. On the other hand, other parts that are not adversely affected can be continued for a necessary time without interrupting chemical peeling.
As an example of the case where it can be easily excised, there can be mentioned a case where it can be excised only with fingers without using other tools.
[0010]
Moreover, the film | membrane base material in the sheet | seat for chemical peeling of this invention shall be previously divided into the small part which can maintain the integrity as a whole and can be easily excised. By partitioning into such small parts in advance, it is possible to easily perform the treatment of removing the film agent in the part corresponding to the part that has an undesirable influence on the skin while leaving other parts. .
The boundary between a small portion and another small portion adjacent to the small portion can be defined as follows. For example, such a boundary can be defined by a machine line or a groove that does not penetrate the membrane substrate.
In addition, the small part in the chemical peeling sheet of the present invention may partition the membrane substrate in any way, but may be configured to partition the membrane substrate in a matrix, for example.
In addition, you may provide the holding means suitable for hold | maintaining a chemical peeling agent in the surface of one side of a film | membrane base material. For example, cotton, hydrogel , agar quality, etc.
[0011]
The chemical peeling sheet described above may not be coated with a chemical peeling agent. Such a chemical peeling tape requires the application of a chemical peeling agent when used, and although it takes some time to use, it is different from the above-mentioned chemical peeling tape in that it can prevent excessive chemical peeling. There is no.
For example, a film substrate having transparency, or a holding means for holding a chemical peeling agent provided on one surface of the film substrate when the other surface side is transparent from one surface side. This is a sheet for chemical peeling, in which the state of the skin can be observed when it is applied to the skin.
In this case, it suffices that the transparent part of the film base or the part through which the other side is transparent from the one side overlaps with the part to which the chemical peeling agent is applied. Of course, it does not matter if the entire membrane substrate is transparent or the other surface side is transparent from one surface side.
[0012]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, a preferred embodiment of a sheet for chemical peeling according to the present invention will be described with reference to the drawings.
[0013]
FIG. 1 is a perspective view showing an overview of a chemical peeling sheet T according to this embodiment, and FIG. 2 is a sectional view thereof.
The chemical peeling sheet T in this embodiment includes a film base 1 formed of silicone so as to have a certain transparency, and a chemical peeling agent 2 applied to, for example, the entire surface of the film base 1. Consists of.
The chemical peeling tape described below is in a state where the chemical peeling agent 2 is applied to the membrane substrate 1. However, the chemical peeling agent does not need to be applied to the membrane substrate 1 from the time of manufacture and sale of the chemical peeling tape. In that case, when using for chemical peeling, the following chemical peeling tape is obtained by applying the chemical peeling agent 2 to the membrane substrate 1.
[0014]
The membrane substrate 1 in this embodiment is formed in a shape corresponding to a human cheek. However, an appropriate shape can be selected as this shape according to the site where chemical peeling is to be performed. It can be shaped like a mask excluding the eyes, mouth and nostril area of the human face, or it can be shaped like a tape having a width of about 2 cm, for example.
Although not limited to this, the back surface (the surface on which the chemical peeling agent 2 is applied) of the film substrate 1 in this embodiment is processed so as to have a certain viscosity. Thereby, this film | membrane base material 1 is easy to hold | maintain the chemical peeling agent 2 on the back surface. On the other hand, the surface of the membrane substrate 1 (the surface on which the chemical peeling agent 2 is not applied) has a reduced viscosity and is processed like a vinyl. By performing such processing, the chemical peeling sheet T has improved handling properties.
The chemical peeling sheet can be attached to the mount in such a manner that it can be easily peeled so that the back side of the sheet is in contact with a predetermined mount. By doing in this way, since the chemical peeling agent 2 and water | moisture content can be prevented now, the handleability improves.
[0015]
On the surface of the above-described membrane substrate 1, grooves 1A, 1A... Having depths that do not penetrate the membrane substrate 1 are provided vertically and horizontally, whereby the membrane substrate 1 has a rectangular small portion 1B, 1B is partitioned. The sizes of the small portions 1B, 1B... May be appropriately determined, for example, in a size of about 0.5 cm to 2 cm in combination with a site where chemical peeling is performed. Although not restricted to this, each small part 1B, 1B ... in this embodiment is formed in about 1 cm square.
The small portions 1B, 1B,... According to this embodiment are formed by arranging the above-described grooves 1A, 1A,... At the boundaries with the adjacent small portions 1B, 1B,. It is supposed to be.
Silicone forming the membrane substrate 1 is a material that can be easily removed even with bare hands. However, the presence of the grooves 1A, 1A,. The parts 1B, 1B... Can be easily removed.
The small portions 1B, 1B,... May be partitioned by replacing some or all of the grooves 1A, 1A,.
[0016]
The chemical peeling agent 2 is glycolic acid, fruit acid (α AHA ), TCA, phenol, lactic acid, salicylic acid, maleic acid, mandelic acid, ethyl pyruvate, glutaronic acid, methyl pyruvate, pyruvic acid, tartaric acid, tartonic acid. , Glyoxylic acid, glycolate ethyl, succinic acid, tretinoin, formic acid, α-hydroxyoctanoic acid, decanoic acid, acetic acid and the like. What is necessary is just to select suitably according to a compatibility with a use, a test subject, etc.
The chemical peeling agent 2 used in the chemical peeling sheet T of this embodiment is glycolic acid, but is not particularly limited as long as it can perform chemical peeling.
For example, the chemical peeling agent 2 may contain 1% to 50% of TCA and 1% to 75% of glycolic acid. You may add another component as needed.
The concentration of glycolic acid can be appropriately changed. The concentration of glycolic acid is not adjusted when the sheet for chemical peeling is used for medical purposes, is adjusted to pH 2.5 to 3.5 when used for esthetics, and pH 3.5 when used for household use. This can be done. This is an example in the case of considering the balance between the strength of the chemical for chemical peeling and the safety. That is, when the pH is higher than pH 2.5, the effect is lowered but the safety is increased. When the pH is lower than 2.5, the effect is increased although the possibility of causing inflammation is increased.
In addition, as the membrane substrate 1, it is also possible to use a material that itself does not have adhesiveness. In this case, it is necessary to apply an adhesive to the back surface of the membrane substrate 1. When such a configuration is employed, the chemical peeling agent and the adhesive as described above can be applied to the back surface of the film substrate 1.
For example, a mixture of the chemical peeling agent 2 and the pressure-sensitive adhesive can be applied to the back surface of the film substrate 1. The pressure-sensitive adhesive in this case also has a function as a holding means according to the present invention.
While the pressure-sensitive adhesive is applied to the portions corresponding to the grooves 1A, 1A,... On the back side of the film substrate 1, the chemical peeling agent 2 as described above can be applied to the other portions. In this case, the adhesive is applied along the outer periphery of the back side of each of the small portions 1B, 1B, and the chemical peeling agent 2 is applied to the other portions. However, how to apply the adhesive and the chemical peeling agent 2 can be appropriately selected depending on the shape of the film substrate 1 and whether or not the small portions 1B, 1B,.
Moreover, the structure which gives adhesiveness to the film | membrane base material 1, or does not use an adhesive is also possible. In this case, you may make it affix on the skin of the film | membrane base material 1 using another means, for example, an adhesive tape. If the main use is only on the skin in a resting state, this chemical peeling tape essentially eliminates the need for affixing. It is not necessary to use an adhesive.
[0017]
An example of a method for using the chemical peeling sheet T will be described. The chemical peeling sheet T is used by being attached to a predetermined position on the skin of a subject to be subjected to chemical peeling. Since the chemical peeling sheet T of this embodiment is used for being attached to the cheek as described above, it is used by being attached to the subject's cheek as shown in FIG. Since the back surface of the film substrate 1 in this embodiment has a certain viscosity, the chemical peeling sheet T can be attached to the skin without using other adhesive materials or adhesive sheets.
[0018]
When the chemical peeling sheet T is pasted, the chemical peeling agent 2 on the back surface thereof acts on the skin. Since the membrane substrate 1 has transparency, the skin state can always be visually recognized even when the chemical peeling sheet T is attached.
[0019]
When the chemical peeling agent 1 is too strong, for example, when an undesirable effect occurs on the skin, the small portion 1B attached to the skin is removed. Due to the presence of the grooves 1A, 1A,..., This removal can be easily performed with bare hands. In this way, the chemical peeling is quickly terminated at a portion where an unfavorable influence has occurred, and the chemical peeling can be continuously performed at other portions.
[0020]
When particularly undesired effects caused by the skin were particularly necessary, a chemical that neutralizes the chemical peeling agent to reduce the effect on the skin was exposed by removing the small portion 1B. Apply to skin. Such drug application may be performed by applying the drug to the place. In addition, a small piece formed in the same shape as the above-described small portion 1B and coated with a predetermined neutralizing agent on one surface thereof is prepared in advance, and this is the portion of the portion from which the small portion 1B is removed. It may be done by pasting on the skin.
[0021]
In the above-described example, the case where the chemical peeling agent 2 is directly applied to one surface of the film substrate 1 is mainly shown. As a modification, a holding means suitable for holding the chemical peeling agent is provided on one surface of the membrane substrate 1, and the chemical peeling agent 2 is held thereon. The holding means can be composed of cotton, hydrogel , agar, etc. in addition to the above-mentioned adhesive. It is also possible to hold the chemical peeling agent 2 by impregnating it.
In this case, it is preferable that the thickness of the holding means is equal to or larger than the thickness of the film substrate 1. That is, when the chemical peeling tape is affixed to the skin in such a manner that the edges are overlapped with each other, a gap is generated between the chemical peeling tape and the skin that are stacked later. By setting the thickness of the holding means formed of a deformable material to a certain value or more and allowing the above-mentioned gap to be filled by the deformation, the generation of such a gap can be prevented. This makes it possible to apply a uniform chemical peeling material to the entire surface of the skin, which is preferable. For example, the thickness of the holding means can be set to at least the same thickness as that of the film substrate 1, and by doing so, it is possible to prevent the generation of a gap during the use of overlapping.
[0022]
【Effect of the invention】
In the sheet for chemical peeling according to the present invention, the membrane substrate has transparency, or the other surface side is transparent from one surface side, so that it is attached to the skin. However, it is possible to visually recognize the state of the skin. Therefore, when an undesirable effect occurs on the skin during chemical peeling, it can be quickly detected and appropriate measures such as termination of chemical peeling can be performed.
[Brief description of the drawings]
FIG. 1 is a perspective view showing an overview of a sheet for chemical peeling according to an embodiment of the present invention.
2 is a cross-sectional view showing a state in which the chemical peeling sheet shown in FIG. 1 is cut in the thickness direction.
FIG. 3 is a perspective view for explaining a usage state of the chemical peeling sheet shown in FIG. 1;
[Explanation of symbols]
1 Membrane Substrate 1A Groove 1B Small Part 2 Chemical Peeling Agent T Chemical Peeling Sheet

Claims (14)

A film substrate having transparency, includes a one surface coated a chemical peeling agent of the membrane substrate, Ri Na is observable skin condition upon paste it into the skin ,
The membrane substrate is preliminarily partitioned into small portions that can maintain the integrity as a whole and can be easily excised, and the small portions partition the membrane substrate in a matrix. It is configured,
Sheet for chemical peeling. A film substrate having transparency, includes a one surface coated a chemical peeling agent of the membrane substrate, Ri Na is observable skin condition upon paste it into the skin ,
The membrane substrate is preliminarily partitioned into small portions that can maintain the integrity as a whole and can be easily excised, and the chemical peeling agent is applied to each of the small portions.
Sheet for chemical peeling. A predetermined adhesive force is given to the one surface of the membrane base material, and the membrane base material can be stuck and fixed to the skin of the subject alone.
The sheet for chemical peeling according to claim 1 or 2 . The film substrate has flexibility to follow the unevenness of the skin,
The sheet for chemical peeling according to claim 1 or 2 . The membrane substrate is made of silicone,
The sheet for chemical peeling according to claim 1 or 2 . Each of the small portions is partitioned between adjacent small portions by a sewing line or a groove that does not penetrate the membrane substrate.
The sheet for chemical peeling according to claim 1 or 2 . The chemical peeling agent is applied to the one surface of the membrane substrate in a state of being mixed with an adhesive that holds the membrane substrate in a state of being attached to the skin.
The sheet for chemical peeling according to claim 1 or 2 . Comprising a membrane substrate that is transparent from one surface side to the other surface side, and a chemical peeling agent applied to any surface of the membrane substrate, and when it is applied to the skin Ri name is a possible observation of the skin of the state,
The membrane substrate is preliminarily partitioned into small portions that can maintain the integrity as a whole and can be easily excised, and the small portions partition the membrane substrate in a matrix. It is configured,
Sheet for chemical peeling. Comprising a membrane substrate that is transparent from one surface side to the other surface side, and a chemical peeling agent applied to any surface of the membrane substrate, and when it is applied to the skin Ri name is a possible observation of the skin of the state,
The membrane substrate is preliminarily partitioned into small portions that can maintain the integrity as a whole and can be easily excised, and the chemical peeling agent is applied to each of the small portions.
Sheet for chemical peeling. It comprises a membrane substrate having transparency and a holding means for holding a chemical peeling agent provided on one surface of the membrane substrate, and the state of the skin when it is attached to the skin Ri Na made to be observed,
The membrane substrate is preliminarily partitioned into small portions that can maintain the integrity as a whole and can be easily excised, and the chemical peeling agent is applied to each of the small portions.
Sheet for chemical peeling. It comprises a membrane substrate having transparency and a holding means for holding a chemical peeling agent provided on one surface of the membrane substrate, and the state of the skin when it is attached to the skin Ri Na made to be observed,
The membrane substrate is preliminarily partitioned into small parts that can maintain the integrity as a whole and can be easily excised, and the holding means is provided in each of the small parts.
Sheet for chemical peeling. Comprising a membrane substrate that is transparent from one surface side to the other surface side, and a holding means for holding a chemical peeling agent provided on one surface of the membrane substrate. Ri name is a possible observation of the skin of the state when affixed to the skin,
The membrane substrate is preliminarily partitioned into small portions that can maintain the integrity as a whole and can be easily excised, and the chemical peeling agent is applied to each of the small portions.
Sheet for chemical peeling. Comprising a membrane substrate that is transparent from one surface side to the other surface side, and a holding means for holding a chemical peeling agent provided on one surface of the membrane substrate. Ri name is a possible observation of the skin of the state when affixed to the skin,
The membrane substrate is preliminarily partitioned into small parts that can maintain the integrity as a whole and can be easily excised, and the holding means is provided in each of the small parts.
Sheet for chemical peeling. The holding means is either hydrogel or agar.
The sheet for chemical peeling according to any one of claims 10 to 13.

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