JP2002255798A - Sheet for chemical peeling - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a sheet for chemical peeling capable of visually confirming the conditions of the skin through the sheet even when the sheet is applied to the skin for carrying out the chemical peeling. SOLUTION: This sheet T for chemical peeling comprises a membrane substrate 1 formed of a silicone and a chemical peeling agent subjected to coating on the whole one surface of the membrane substrate 1. The membrane substrate 1 is transparent and the conditions of the skin can visually be confirmed through the membrane substrate 1 even in the state thereof applied to the skin. Grooves 1A having a depth so as not to pass through the membrane substrate 1 are crosswise formed in the surface of the membrane substrate 1. Thereby, the membrane substrate 1 is divided into small parts 1B arranged in the form of a matrix. The respective small parts 1B can readily be excised. When unfavorable effects on the skin are produced, the small parts 1B facing to the skin can rapidly be removed.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to improvement of skin quality such as rough and dry skin, removal of acne, fine wrinkles, and removal of spots and dullness (pigmentation such as senile pigment spots). The present invention relates to a chemical peeling technique applied to a chemical peeling technique, and more particularly to a chemical peeling sheet used for applying a chemical peeling agent to the skin of a subject when performing chemical peeling.

[0002]

BACKGROUND OF THE INVENTION Recently, cosmetics containing a low concentration of a chemical peeling agent such as .alpha.-hydroxyacid (AHA), which is effective in improving skin condition and wrinkling or blotting of skin, for example. Has been used extensively. In Europe and the United States, the removal of wrinkles and spots has been established as one of the medical fields. Accompanying this, medical research on such treatments has been widely conducted in Japan. Skin treatment using a peeling agent is generally called chemical peeling. Such treatment, called chemical peeling, involves applying a peeling agent, such as acetic acid trichloride (TCA), phenol, fruit acid (eg, α-hydroxyacid (AHA)), to the skin as an aqueous solution of a suitable concentration for a suitable time. It is performed by creating a chemical burn (corrosion) or by giving the skin a moderate irritation. In other words, the skin is treated by applying the above-mentioned drug to the skin, peeling off a part of the keratin and epidermis of the skin, and activating cells to promote regeneration of new cells of the skin.

[0003] In order to perform chemical peeling, it is necessary to apply a chemical peeling agent of an appropriate concentration to the skin, but directly applying the chemical peeling agent to the skin of a subject is troublesome in terms of preparation and application work. In many cases, coating residue and coating unevenness are likely to occur. In consideration of such a point, it is conceivable that the chemical peeling agent is easily applied to the skin by attaching a chemical peeling sheet made of a cloth to which the chemical peeling agent has been applied in advance to the skin.

[0004] By the way, chemical peeling is intended to regenerate the skin by applying a certain load to the skin. Therefore, if the concentration of the chemical peeling agent is high or the application time of the chemical peeling agent is long, inflammation may occur. Or undesired effects such as excessive denaturation of cells and proteins may occur on the skin. How to achieve the best results with regard to the concentration of the chemical peeling agent and the time for applying the chemical peeling sheet depends on the experience of the treating physician and the results of preliminary tests. Although some predictions can be made on the basis of this, it is extremely difficult to predict the reaction to the drug because the response to the drug varies greatly from person to person and the reaction that occurs depending on the physical condition of the subject changes daily.

[0005] When chemical peeling causes undesired effects such as frosting (whitening due to protein denaturation of the skin), rash, and redness on the skin of the subject, it is essential to immediately stop the treatment. It is necessary to apply another agent for neutralizing the peeling agent to the skin. However, with an opaque chemical peeling sheet, it is not possible to confirm the state of the skin due to the effect of the chemical peeling agent while the sheet is still attached to the skin.
If the effect on the skin cannot be confirmed immediately, the judgment of interruption of treatment when chemical peeling is excessively performed tends to be delayed. In other words, in order to make the chemical peeling sheet practical, not only there is an advantage in the application operation, but also it is possible to perform treatment while confirming whether or not undesired effects are occurring on the skin. Need to be something. Only when this can be realized will it be possible to achieve sufficient diffusion. On the other hand, in performing chemical peeling, it is important that the chemical peeling agent acts uniformly on each part of the skin to be treated. When treatment is performed using a chemical peeling sheet, it is necessary to remove the chemical peeling sheet when frosting, rash, redness, inflammation, etc. occur on a part of the skin. However, when the entire chemical peeling sheet is removed,
The treatment for the portion where no inflammation or the like has occurred is also ended at the same time. In such a case, the treatment for such a part becomes insufficient, and it is difficult to perform a uniform treatment for each part of the skin to be treated with the conventional chemical peeling sheet.

[0006]

An object of the present invention is to provide a practical sheet for chemical peeling. That is, an object of the present invention is to provide a chemical peeling sheet having both an advantage of easy application operation and an advantage of performing treatment of chemical peeling while checking the properties of the skin. In addition, when an unfavorable effect occurs on the skin, the treatment can be interrupted or a neutralizing agent can be quickly applied to the relevant portion, and the chemical peeling can be continued for other portions. It is a further object to provide a sheet for chemical peeling.

[0007]

The chemical peeling sheet according to the present invention for solving the above-mentioned problems is as follows. That is, a film base having transparency, or a film base made to be transparent from one side to the other side, and a chemical peeling agent applied to one side of the film base. And a sheet for chemical peeling, wherein the state of the skin can be observed when the sheet is applied to the skin. According to such a sheet for chemical peeling, it is possible to always observe the properties of the skin through the film base material even during the chemical peeling by sticking it to the skin. Therefore, if any undesired effects occur on the skin, it can be detected at an early stage, and treatment can be interrupted or a neutralizing agent can be applied immediately, thereby improving the safety of chemical peeling. Will be able to The transparent portion of the membrane substrate and the portion where one surface side is transparent from the other surface side must overlap with the portion to which the chemical peeling agent is applied. What is necessary is just a predetermined range of a material. Naturally, the entire film base material may have transparency or be transparent from one surface side to the other surface side.

[0008] The film base material in the chemical peeling sheet of the present invention may be any material as long as the properties of the skin can be visually recognized through the chemical peeling sheet even when the chemical peeling sheet is attached. It may be transparent or may not be completely transparent, but may be translucent enough to make the skin characteristics visible. In addition, even if the chemical peeling sheet is attached, it may be composed of not one layer but a multilayer as long as it allows the skin properties to be visually recognized through the sheet. For example, it is also possible to constitute this membrane base from a layer for maintaining the shape of the membrane base and a layer for holding the chemical peeling agent. Further, the membrane base material may be a mesh-like material formed of an opaque material, or a multilayer material including such a mesh-like layer, as long as the properties of the skin can be visually recognized in the attached state. A predetermined adhesive strength can be given to the one surface of the film substrate. Thereby, the film base material can be stuck and fixed on the skin of the subject by itself. It is possible to use another adhesive sheet or the like when attaching the film base material to the skin. However, if the film base material alone can be fixed to the skin, it is convenient for use. In this case, the film substrate itself may have tackiness, or the pressure-sensitive adhesive may be applied to a predetermined portion of the one surface of the non-tacky film substrate. The pressure-sensitive adhesive may be applied only to a portion different from the site where the chemical peeling agent is applied, or may be applied by mixing with the chemical peeling agent. The film substrate may also have flexibility to follow skin irregularities. By using a flexible film base material, the chemical peeling agent can be sufficiently brought into contact with each part of the skin. Here, when the film substrate has transparency, it can be formed of silicone. Silicone is a material having transparency, and its surface properties can be changed in many ways by a processing method, so that it is convenient to use it as the film substrate of the present invention. For example, one surface of silicone formed into a film shape is processed to have a certain viscosity, and the other surface is processed to be a resin having a certain hardness, and one surface of the one surface having a viscosity. When a chemical peeling agent is applied to a sheet, the film base can be composed of one layer, so that the constitution of the chemical peeling sheet can be simplified.

The membrane substrate in the chemical peeling sheet of the present invention can be configured so that a part thereof can be easily cut off. In this way, if an unfavorable effect on the skin can be confirmed during chemical peeling, a part of the film substrate corresponding to that position is immediately cut off to minimize the effect on the skin. Can be held down. On the other hand, the other parts that do not have an undesired effect can be continued for a required time without interrupting the chemical peeling. As an example of a case where the cutting can be easily performed, there is a case where the cutting can be performed only with the finger without using other tools.

[0010] In addition, the membrane substrate in the chemical peeling sheet of the present invention can maintain the integrity as a whole and can be a part preliminarily partitioned into small parts that can be easily cut off. . By preliminarily partitioning into such small parts, it is possible to easily perform the treatment of removing the film agent in the part corresponding to the part where the undesired influence is present on the skin, leaving the other part. . The boundary between a small part and another adjacent small part can be partitioned as follows. For example, such boundaries can be demarcated by perforations or grooves that do not penetrate the membrane substrate. In addition, the small portion of the chemical peeling sheet of the present invention may be any one that divides the film base material, but may be one that divides the film base material in a matrix, for example. Incidentally, a holding means suitable for holding the chemical peeling agent may be provided on one surface of the film base material. For example, cotton, high rod gel,
Such as agar.

The chemical peeling sheet described above does not have to be coated with a chemical peeling agent. Since such a chemical peeling tape requires the application of a chemical peeling agent when used,
Although its use requires some labor, it is no different from the above-mentioned chemical peeling tape in that excessive chemical peeling can be prevented. For example, when the film substrate having transparency, or the other surface side is made to be transparent from one surface side, provided on one surface of the film substrate,
A sheet for chemical peeling, which comprises a holding means for holding a chemical peeling agent, and which allows the state of the skin to be observed when the sheet is adhered to the skin, corresponds to this. In this case, it is sufficient that the transparent portion of the film base material and the portion where the one surface side is transparent from the other surface side overlap with the portion where the chemical peeling agent is applied. Naturally, the entire film base material may have transparency or be transparent from one surface side to the other surface side.

[0012]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS A preferred embodiment of a chemical peeling sheet according to the present invention will be described below with reference to the drawings.

FIG. 1 is a perspective view showing an overview of a chemical peeling sheet T according to this embodiment, and FIG.
It is sectional drawing. The sheet T for chemical peeling in this embodiment is composed of a film substrate 1 formed of silicone so as to have a certain degree of transparency, and a chemical peeling agent 2 applied to, for example, one entire surface of the film substrate 1. Consists of The chemical peeling tape described below is a state in which the chemical peeling agent 2 is applied to the film substrate 1. However, the chemical peeling agent does not need to be applied to the film substrate 1 from the time of manufacturing and selling the chemical peeling tape. In that case, the following chemical peeling tape is obtained by applying the chemical peeling agent 2 to the film base material 1 when using for chemical peeling.

The film substrate 1 in this embodiment is formed in a shape corresponding to a human cheek. However, this shape can be appropriately selected according to the site where chemical peeling is to be performed. It may be shaped like a mask excluding the eyes, mouth and nostrils around a human face, or it may be shaped like a tape with a width of about 2 cm, for example. The back surface (the surface on the side on which the chemical peeling agent 2 is applied) of the film substrate 1 in this embodiment is processed so as to have a certain viscosity, although not limited thereto.
As a result, the film substrate 1 is made of a chemical peeling agent 2
On the back surface thereof. On the other hand, the surface of the film substrate 1 (the surface on which the chemical peeling agent 2 is not applied) has a reduced viscosity and is processed like vinyl. By performing such processing, the handleability of the chemical peeling sheet T is enhanced. In addition, this sheet for chemical peeling
It is also possible to affix to the backing sheet such that the back side of the backing sheet contacts a predetermined backing sheet and can be easily peeled off. By doing so, the chemical peeling agent 2 and moisture can be prevented from evaporating, so that the handleability is improved.

On the surface of the above-mentioned film base 1, grooves 1A, 1A,... Part 1B, 1B
It is divided into ... The size of the small parts 1B, 1B ...
The size may be appropriately determined, for example, in a size of about 0.5 cm to 2 cm in accordance with the site where chemical peeling is performed. Although not limited to this, each of the small portions 1B, 1B... In this embodiment is formed to be approximately 1 cm square.
Are formed by arranging the above-described grooves 1A, 1A,... At the boundaries between adjacent small portions 1B, 1B,. It is something to do. The silicone forming the film substrate 1 is a material that can be easily cut off even with bare hands, but the presence of the grooves 1A, 1A,... Parts 1B, 1B ...
Each excision can be easily performed. still,
By substituting a part or all of the grooves 1A, 1A,... With perforation lines, the small parts 1B, 1B,.

Chemical peeling agent 2 includes glycolic acid, fruit acid (αDHA), TCA, phenol, lactic acid, salicylic acid, maleic acid, mandelic acid, ethyl pyruvate, glutaronic acid, methyl pyruvate, pyruvate, tartaric acid, It may contain at least one of tartonic acid, glyoxylic acid, glycolate ethyl, succinic acid, tretinoin, formic acid, α-hydroxyoctanoic acid, decanoic acid, acetic acid and the like. What is necessary is just to select suitably according to a use, compatibility with a test subject, etc. The chemical peeling agent 2 used in the chemical peeling sheet T of this embodiment is glycolic acid, but is not particularly limited as long as it can perform chemical peeling. For example, the chemical peeling agent 2 may contain 1% to 50% of TCA and 1% to 75% of glycolic acid. Other components may be added as needed.
The concentration of glycolic acid can be appropriately changed. The concentration of glycolic acid is pH-unadjusted when the chemical peeling sheet is used for medical use, pH 2.5-3.5 when used for beauty treatment, and pH 3.5 when used for home use. The above can be considered. This is an example in which the balance between the strength of a drug for performing chemical peeling and safety is considered. That is, when the pH is higher than pH 2.5, the effect is reduced but the safety is increased, and when the pH is lower than pH 2.5, the effect is increased although the possibility of inflammation is increased. In addition, it is also possible to use what does not itself have adhesiveness as the film base material 1. In this case, it is necessary to apply an adhesive to the back surface of the film substrate 1. When such a configuration is adopted, the above-described chemical peeling agent and pressure-sensitive adhesive can be applied to the back surface of the film substrate 1. For example, a mixture of the chemical peeling agent 2 and the adhesive can be applied to the back surface of the film substrate 1. In this case, the pressure-sensitive adhesive also has a function as a holding means according to the present invention. On the back side of the film substrate 1, an adhesive may be applied to the portions corresponding to the grooves 1A, 1A,..., And the chemical peeling agent 2 as described above may be applied to other portions. In this case, an adhesive is applied along the outer periphery on the back side of each of the small portions 1B, 1B, and the chemical peeling agent 2 is applied to other portions. However, how to apply the pressure-sensitive adhesive and the chemical peeling agent 2 can be appropriately selected according to the shape of the film base material 1 and whether or not to perform division into the small parts 1B, 1B, and the like. In addition, a configuration in which the film substrate 1 is made to have adhesiveness or a structure without using an adhesive is also possible. In this case, the film substrate 1 may be attached to the skin using another means, for example, an adhesive tape. If it is mainly used only for resting on the skin in a resting state, this chemical peeling tape essentially eliminates the need for affixing means. There is no need to use an adhesive.

An example of a method for using the chemical peeling sheet T will be described. The sheet for chemical peeling T is used by attaching it to a predetermined position on the skin of the subject to be subjected to chemical peeling. Since the chemical peeling sheet T of this embodiment is to be attached to the cheek as described above, it is used by attaching it to the cheek of the subject as shown in FIG. Since the back surface of the film substrate 1 in this embodiment has a certain viscosity, the chemical peeling sheet T can be attached to the skin without using another adhesive material or an adhesive sheet.

When the chemical peeling sheet T is adhered, the chemical peeling agent 2 on the back surface acts on the skin. Since the film substrate 1 has transparency, the state of the skin can always be visually recognized even in the state where the chemical peeling sheet T is stuck.

If the chemical peeling agent 1 has an unfavorable effect on the skin such as when it is too strong, the small portion 1B adhered to the skin is removed. Due to the presence of the grooves 1A, 1A,..., The removal can be easily performed with bare hands. In this way, chemical peeling can be quickly terminated for a portion where an undesired effect has occurred, and chemical peeling can be continuously performed for other portions.

When it is particularly necessary, for example, when the undesired effect of the skin is large, an agent which neutralizes the chemical peeling agent and suppresses the effect on the skin to a small extent is obtained by removing the small portion 1B. Apply to exposed skin. Such application of the medicine may be performed by applying the medicine to the place. In addition, the above-mentioned small portion 1B
A small piece having the same shape as that of the above and having one surface coated with a predetermined neutralizing agent is prepared in advance, and this is attached to the skin of the portion from which the small portion 1B has been removed. May be.

In the above-described example, the case where the chemical peeling agent 2 is directly applied to one surface of the film base material 1 is mainly shown. As a modified example, one in which a holding means suitable for holding the chemical peeling agent is provided on one surface of the film base material 1 and the chemical peeling agent 2 is held on the holding means can be cited. The holding means can be made of cotton, hydrod gel, agar, or the like in addition to the above-mentioned adhesive. It is also possible to hold the chemical peeling agent 2 by impregnating it. In this case, it is preferable that the thickness of the holding means is not less than a certain value as compared with the thickness of the film substrate 1. That is, when the chemical peeling tape is attached to the skin such that the edges are overlapped with each other, a gap is generated between the chemical peeling tape and the skin that are subsequently stacked. By setting the thickness of the holding means formed of a deformable material to be equal to or greater than a certain value and allowing the deformation to fill the gap, the occurrence of the gap can be prevented. This makes it possible to uniformly apply the chemical peeling material to the entire surface of the skin, which is preferable. For example, the thickness of the holding means can be made at least as thick as that of the film base material 1, thereby making it possible to prevent the generation of a gap at the time of overlapping use.

[0022]

According to the chemical peeling sheet of the present invention, the film base material has transparency or is made so that one surface side can be transparent from the other surface side. It is possible to visually recognize the condition of the skin even when it is stuck on the skin. Therefore, when an unfavorable effect on the skin occurs during chemical peeling, it is possible to quickly detect the unfavorable effect and appropriately perform treatment such as termination of chemical peeling.

[Brief description of the drawings]

FIG. 1 is a perspective view showing an overview of a chemical peeling sheet according to an embodiment of the present invention.

FIG. 2 is a sectional view showing a state in which the chemical peeling sheet shown in FIG. 1 is cut in a thickness direction.

FIG. 3 is a perspective view for explaining a use state of the chemical peeling sheet shown in FIG. 1;

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Membrane base material 1A Groove 1B Small part 2 Chemical peeling agent T Sheet for chemical peeling

Claims (13)

[Claims] 1. A film base material having transparency and a chemical peeling agent applied to one surface of the film base material, so that the skin condition can be observed when the film base material is applied to the skin. A sheet for chemical peeling. 2. A method according to claim 1, wherein a predetermined adhesive force is applied to said one surface of said membrane base material, and said membrane base material can be stuck and fixed on a subject's skin by itself. Item 7. The chemical peeling sheet according to Item 1. 3. The chemical peeling sheet according to claim 1, wherein the film substrate has flexibility to follow unevenness of the skin. 4. The chemical peeling sheet according to claim 1, wherein the film substrate is made of silicone. 5. The membrane base according to claim 1, wherein the membrane base is configured so that a part thereof can be easily cut off.
The sheet for chemical peeling according to the above item. 6. The membrane substrate according to claim 1, wherein the membrane substrate is preliminarily partitioned into small portions that can maintain the integrity as a whole and a part of which can be easily cut off. Sheet for chemical peeling. 7. The chemical peeling device according to claim 6, wherein each of the small portions is defined by a perforation line or a groove that does not penetrate the membrane substrate, between adjacent small portions. Sheet. 8. The chemical peeling sheet according to claim 6, wherein the small portion is configured to partition the film base material in a matrix. 9. The chemical peeling agent is applied to the one surface of the film base material in a state where the chemical peeling agent is mixed with an adhesive for holding the film base material attached to the skin.
The sheet for chemical peeling according to claim 2. 10. A film base material which is transparent from one surface side to the other surface side, and a chemical peeling agent applied to any surface of the film base material. A chemical peeling sheet that allows you to observe the condition of the skin when pasted. 11. A film base material having transparency, and holding means for holding a chemical peeling agent provided on one surface of the film base material, which is attached to the skin. A chemical peeling sheet that allows you to observe the skin condition at the time. 12. A film base material that is transparent from one surface side to another surface side, and holding means for holding a chemical peeling agent provided on one surface of the film base material. A sheet for chemical peeling that allows the skin condition to be observed when it is applied to the skin. 13. The holding means according to claim 11, wherein the holding means is one of cotton, hydrogel, and agar.
2. The sheet for chemical peeling according to 2.