JP5036561B2 - 心拍変動を使用する電気的刺激の制御 - Google Patents

心拍変動を使用する電気的刺激の制御 Download PDF

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Publication number
JP5036561B2
JP5036561B2 JP2007552170A JP2007552170A JP5036561B2 JP 5036561 B2 JP5036561 B2 JP 5036561B2 JP 2007552170 A JP2007552170 A JP 2007552170A JP 2007552170 A JP2007552170 A JP 2007552170A JP 5036561 B2 JP5036561 B2 JP 5036561B2
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Prior art keywords
stimulation
parameter
hrv
pacing
pulse
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Japanese (ja)
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JP2008526456A (ja
JP2008526456A5 (https=
Inventor
パストア，ジョセフ・エム
サロ，ロドニー・ダブリュ
カールソン，ジェラード・エム
クラマー，アンドリュー・ピイ
ディング，ジアン
ユ，インホン
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カーディアック ペースメイカーズ， インコーポレイテッド
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Priority claimed from US11/037,309 external-priority patent/US7672725B2/en
Priority claimed from US11/037,723 external-priority patent/US7580745B2/en
Application filed by カーディアック ペースメイカーズ， インコーポレイテッド filed Critical カーディアック ペースメイカーズ， インコーポレイテッド
Publication of JP2008526456A publication Critical patent/JP2008526456A/ja
Publication of JP2008526456A5 publication Critical patent/JP2008526456A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36592—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by the heart rate variability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02405—Determining heart rate variability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029—Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4035—Evaluating the autonomic nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions

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  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Electrotherapy Devices (AREA)
JP2007552170A 2005-01-18 2006-01-12 心拍変動を使用する電気的刺激の制御 Expired - Fee Related JP5036561B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US11/037,309 US7672725B2 (en) 2005-01-18 2005-01-18 Method and apparatus for using heart rate variability as a safety check in electrical therapies
US11/037,723 US7580745B2 (en) 2005-01-18 2005-01-18 Method and apparatus for using heart rate variability to control maximum tracking rate in pacing therapy
US11/037,308 2005-01-18
US11/037,723 2005-01-18
US11/037,308 US7672724B2 (en) 2005-01-18 2005-01-18 Method and apparatus for optimizing electrical stimulation parameters using heart rate variability
US11/037,309 2005-01-18
PCT/US2006/000963 WO2006078519A2 (en) 2005-01-18 2006-01-12 Control of electrical stimulation using heart rate variability

Related Child Applications (1)

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JP2012009614A Division JP5312619B2 (ja) 2005-01-18 2012-01-20 心拍変動を使用する電気的刺激の制御

Publications (3)

Publication Number Publication Date
JP2008526456A JP2008526456A (ja) 2008-07-24
JP2008526456A5 JP2008526456A5 (https=) 2009-03-26
JP5036561B2 true JP5036561B2 (ja) 2012-09-26

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JP2007552170A Expired - Fee Related JP5036561B2 (ja) 2005-01-18 2006-01-12 心拍変動を使用する電気的刺激の制御
JP2012009614A Expired - Fee Related JP5312619B2 (ja) 2005-01-18 2012-01-20 心拍変動を使用する電気的刺激の制御

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Country Status (4)

Country Link
US (2) US7672724B2 (https=)
EP (2) EP2554216B1 (https=)
JP (2) JP5036561B2 (https=)
WO (1) WO2006078519A2 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6678547B2 (en) * 2001-03-08 2004-01-13 Cardiac Pacemakers, Inc. Cardiac rhythm management system using time-domain heart rate variability indicia
US7672725B2 (en) * 2005-01-18 2010-03-02 Cardiac Pacemakers, Inc. Method and apparatus for using heart rate variability as a safety check in electrical therapies
US7672724B2 (en) * 2005-01-18 2010-03-02 Cardiac Pacemakers, Inc. Method and apparatus for optimizing electrical stimulation parameters using heart rate variability
US7580745B2 (en) 2005-01-18 2009-08-25 Cardiac Pacemakers, Inc. Method and apparatus for using heart rate variability to control maximum tracking rate in pacing therapy
US7561923B2 (en) * 2005-05-09 2009-07-14 Cardiac Pacemakers, Inc. Method and apparatus for controlling autonomic balance using neural stimulation
US20080091255A1 (en) * 2006-10-11 2008-04-17 Cardiac Pacemakers Implantable neurostimulator for modulating cardiovascular function
WO2008070189A2 (en) 2006-12-06 2008-06-12 The Cleveland Clinic Foundation Method and system for treating acute heart failure by neuromodulation
US8308649B2 (en) * 2007-03-23 2012-11-13 St. Jude Medical Ab Implantable cardiac device and method for monitoring the status of a cardiovascular disease
US7751889B1 (en) * 2007-04-11 2010-07-06 Pacesetter, Inc. Closed loop programming for individual adjustment of electro-mechanical synchrony
US20080306564A1 (en) * 2007-06-11 2008-12-11 Cardiac Pacemakers, Inc Method and apparatus for short-term heart rate variability monitoring and diagnostics
JP5292416B2 (ja) * 2008-03-13 2013-09-18 カーディアック ペースメイカーズ， インコーポレイテッド 断続的な治療を制御するための自律神経平衡監視
US8532769B2 (en) * 2009-10-30 2013-09-10 Medtronic, Inc. Heart rate variability distinction
US9402550B2 (en) * 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
EP2948217B1 (en) * 2013-01-25 2018-03-14 Cardiac Pacemakers, Inc. Systems to identify cardiac dysynchrony
GB2526249B (en) * 2014-03-20 2016-06-29 Branton Jakes Device for the automated non-invasive dynamically adaptive electrical stimulation of the vagus nerve
WO2015179634A2 (en) 2014-05-22 2015-11-26 CARDIONOMIC, Inc. Catheter and catheter system for electrical neuromodulation
EP3194017A1 (en) 2014-09-08 2017-07-26 Cardionomic, Inc. Methods for electrical neuromodulation of the heart
US10493278B2 (en) * 2015-01-05 2019-12-03 CARDIONOMIC, Inc. Cardiac modulation facilitation methods and systems
CN109310863A (zh) 2016-03-09 2019-02-05 卡迪诺米克公司 心脏收缩性神经刺激系统和方法
EP3664703A4 (en) 2017-09-13 2021-05-12 Cardionomic, Inc. NEUROSTIMULATION SYSTEMS AND METHODS FOR INFLUENCING HEART CONTRACTILITY
CN112292178A (zh) * 2018-06-14 2021-01-29 美敦力公司 用于心脏重塑的心脏起搏治疗的递送
JP2021535776A (ja) 2018-08-13 2021-12-23 カーディオノミック，インク． 心収縮及び／又は弛緩に作用するシステムおよび方法
WO2020080986A1 (en) * 2018-10-17 2020-04-23 Maquet Critical Care Ab Lung recruitment in mechanical ventilation
EP3648470B1 (en) * 2018-11-05 2025-06-04 GN Hearing A/S Hearing system with heart condition alert and related methods
CA3137307A1 (en) 2019-05-06 2020-11-12 CARDIONOMIC, Inc. Systems and methods for denoising physiological signals during electrical neuromodulation
EP4640269A3 (en) 2019-12-31 2025-12-31 Boston Scientific Neuromodulation Corporation AUTOMATIC INPUT DETERMINATION FOR CLOSED-LOOP ALGORITHMS FOR OPTIMIZING STIMULATION PARAMETERS
WO2021257399A1 (en) 2020-06-16 2021-12-23 CARDIONOMIC, Inc. Chronically implantable systems and methods for affecting cardiac contractility and/or relaxation
US20240017072A1 (en) * 2022-07-14 2024-01-18 Saluda Medical Pty Ltd Improved Neurostimulation Therapy Monitoring
CN115554605B (zh) * 2022-11-04 2026-01-30 西安交通大学 一种迷走神经刺激装置和刺激参数优化方法
US20250040868A1 (en) * 2023-08-03 2025-02-06 Medtronic, Inc. System for reproductive monitoring

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5265617A (en) 1991-02-20 1993-11-30 Georgetown University Methods and means for non-invasive, dynamic tracking of cardiac vulnerability by simultaneous analysis of heart rate variability and T-wave alternans
US5842997A (en) * 1991-02-20 1998-12-01 Georgetown University Non-invasive, dynamic tracking of cardiac vulnerability by simultaneous analysis of heart rate variability and T-wave alternans
US5437285A (en) * 1991-02-20 1995-08-01 Georgetown University Method and apparatus for prediction of sudden cardiac death by simultaneous assessment of autonomic function and cardiac electrical stability
US5203326A (en) * 1991-12-18 1993-04-20 Telectronics Pacing Systems, Inc. Antiarrhythmia pacer using antiarrhythmia pacing and autonomic nerve stimulation therapy
IT1259358B (it) * 1992-03-26 1996-03-12 Sorin Biomedica Spa Dispositivo impiantabile per la rilevazione ed il controllo del tono simpatico-vagale
US5291400A (en) * 1992-04-09 1994-03-01 Spacelabs Medical, Inc. System for heart rate variability analysis
US5891044A (en) * 1992-10-06 1999-04-06 Gw Scientific, Inc. Detection of abnormal and induction of normal heart rate variability
US5318591A (en) 1992-11-23 1994-06-07 Siemens Pacesetter, Inc. Implantable cardioverter-defibrillator having early charging capability
WO1995003739A1 (en) * 1993-08-03 1995-02-09 Peter Walter Kamen A method of measuring autonomic activity of a patient
US5522854A (en) * 1994-05-19 1996-06-04 Duke University Method and apparatus for the prevention of arrhythmia by nerve stimulation
US5549641A (en) 1994-10-31 1996-08-27 Incontrol, Inc. Atrial fibrillation type selective cardiovertor and method
US5466245A (en) * 1994-11-15 1995-11-14 Cardiac Pacemakers, Inc. Method and apparatus to continuously optimize the A-V delay in a dual chamber pacemaker
US5540725A (en) * 1995-07-11 1996-07-30 Pacesetter, Inc. Upper rate response for implantable pacemaker based on atrial lock interval pacing
US5755671A (en) * 1995-10-05 1998-05-26 Massachusetts Institute Of Technology Method and apparatus for assessing cardiovascular risk
US6035233A (en) * 1995-12-11 2000-03-07 Intermedics Inc. Implantable medical device responsive to heart rate variability analysis
US5749900A (en) * 1995-12-11 1998-05-12 Sulzer Intermedics Inc. Implantable medical device responsive to heart rate variability analysis
US5603331A (en) * 1996-02-12 1997-02-18 Cardiac Pacemakers, Inc. Data logging system for implantable cardiac device
DE19609409C2 (de) 1996-03-04 2000-01-20 Biotronik Mess & Therapieg Therapiegerät
SE9603635D0 (sv) * 1996-10-04 1996-10-04 Pacesetter Ab Implantable stimulator
US5893882A (en) * 1996-12-17 1999-04-13 Medtronic, Inc. Method and apparatus for diagnosis and treatment of arrhythmias
WO1998040014A1 (en) * 1997-03-10 1998-09-17 Robin Medical Inc. Method and apparatus for the assessment and display of variability in mechanical activity of the heart, and enhancement of ultrasound contrast imaging by variability analysis
SE9701121D0 (sv) * 1997-03-26 1997-03-26 Pacesetter Ab Implantable heart stimulator
US6042548A (en) * 1997-11-14 2000-03-28 Hypervigilant Technologies Virtual neurological monitor and method
EP1063917B1 (en) * 1998-03-17 2008-12-24 The University Of Virginia Patent Foundation Method and apparatus for the early diagnosis of subacute, potentially catastrophic illness
US5941831A (en) * 1998-04-03 1999-08-24 Pacesetter, Inc. Method for diagnosing cardiac arrhythmias using interval irregularity
US6021351A (en) * 1998-05-11 2000-02-01 Cardiac Pacemakers, Inc. Method and apparatus for assessing patient well-being
US6301499B1 (en) * 1998-06-08 2001-10-09 Cardiac Pacemakers, Inc. Heart rate variability as an indicator of exercise capacity
US6026320A (en) * 1998-06-08 2000-02-15 Cardiac Pacemakers, Inc. Heart rate variability as an indicator of exercise capacity
US6370427B1 (en) 1998-07-23 2002-04-09 Intermedics, Inc. Method and apparatus for dual chamber bi-ventricular pacing and defibrillation
US6292693B1 (en) * 1998-11-06 2001-09-18 Impulse Dynamics N.V. Contractility enhancement using excitable tissue control and multi-site pacing
US6253107B1 (en) * 1998-12-09 2001-06-26 Cambridge Heart, Inc. Cardiac pacing to induce heart rate variability
JP2000166889A (ja) * 1998-12-11 2000-06-20 Inst Of Physical & Chemical Res 心拍変動推定方法およびその装置
US6434424B1 (en) 1998-12-28 2002-08-13 Medtronic, Inc. Regularization of ventricular rate during atrial tachyarrhythmia
AU2977700A (en) 1999-01-29 2000-08-18 Evgueni N. Bogomolov Personal physiological monitor
US6358201B1 (en) * 1999-03-02 2002-03-19 Doc L. Childre Method and apparatus for facilitating physiological coherence and autonomic balance
US6508771B1 (en) 1999-03-05 2003-01-21 Medtronic, Inc. Method and apparatus for monitoring heart rate
US6190324B1 (en) * 1999-04-28 2001-02-20 Medtronic, Inc. Implantable medical device for tracking patient cardiac status
US6341236B1 (en) * 1999-04-30 2002-01-22 Ivan Osorio Vagal nerve stimulation techniques for treatment of epileptic seizures
US6430438B1 (en) * 1999-05-21 2002-08-06 Cardiac Pacemakers, Inc. Cardiac rhythm management system with atrial shock timing optimization
US6390986B1 (en) * 1999-05-27 2002-05-21 Rutgers, The State University Of New Jersey Classification of heart rate variability patterns in diabetics using cepstral analysis
US6314321B1 (en) 1999-06-30 2001-11-06 Cardiac Pacemakers, Inc. Therapy-selection methods for implantable heart monitors
US6450942B1 (en) 1999-08-20 2002-09-17 Cardiorest International Ltd. Method for reducing heart loads in mammals
US7062314B2 (en) * 1999-10-01 2006-06-13 Cardiac Pacemakers, Inc. Cardiac rhythm management device with triggered diagnostic mode
US6678547B2 (en) * 2001-03-08 2004-01-13 Cardiac Pacemakers, Inc. Cardiac rhythm management system using time-domain heart rate variability indicia
US6480733B1 (en) * 1999-11-10 2002-11-12 Pacesetter, Inc. Method for monitoring heart failure
US7194305B1 (en) * 2000-04-07 2007-03-20 Cardiac Pacemakers, Inc. Cardiac rhythm management system with optimization of cardiac performance using heart rate
EP1172125B1 (en) * 2000-07-11 2005-03-09 SORIN BIOMEDICA CRM S.r.l. An implantable heart stimulation system with automatic mode switching controlled by sympatho-vagal balance
US6856829B2 (en) * 2000-09-07 2005-02-15 Denso Corporation Method for detecting physiological condition of sleeping patient based on analysis of pulse waves
US6628988B2 (en) * 2001-04-27 2003-09-30 Cardiac Pacemakers, Inc. Apparatus and method for reversal of myocardial remodeling with electrical stimulation
US7778703B2 (en) * 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Selective nerve fiber stimulation for treating heart conditions
DE10151089A1 (de) * 2001-10-13 2003-04-17 Biotronik Mess & Therapieg Vorrichtung zur Vorhersage von Tachyarrythmien
US7215992B2 (en) * 2001-10-31 2007-05-08 Cardiac Pacemakers, Inc. Method for ischemia detection by implantable cardiac device
US6973349B2 (en) * 2001-12-05 2005-12-06 Cardiac Pacemakers, Inc. Method and apparatus for minimizing post-infarct ventricular remodeling
US7123959B2 (en) * 2002-03-25 2006-10-17 Cardiac Pacemakers, Inc. Method and apparatus for preventing cardiac arrhythmias with endovascular stimulation
US6922585B2 (en) * 2002-04-05 2005-07-26 Medtronic, Inc. Method and apparatus for predicting recurring ventricular arrhythmias
US7133718B2 (en) * 2003-06-19 2006-11-07 Medtronic, Inc. Method and apparatus for temporarily varying a parameter in an implantable medical device
US7580745B2 (en) * 2005-01-18 2009-08-25 Cardiac Pacemakers, Inc. Method and apparatus for using heart rate variability to control maximum tracking rate in pacing therapy
US7672724B2 (en) 2005-01-18 2010-03-02 Cardiac Pacemakers, Inc. Method and apparatus for optimizing electrical stimulation parameters using heart rate variability
US7672725B2 (en) 2005-01-18 2010-03-02 Cardiac Pacemakers, Inc. Method and apparatus for using heart rate variability as a safety check in electrical therapies

Also Published As

Publication number Publication date
JP2008526456A (ja) 2008-07-24
JP2012071206A (ja) 2012-04-12
JP5312619B2 (ja) 2013-10-09
WO2006078519A3 (en) 2007-04-19
WO2006078519A2 (en) 2006-07-27
EP2554216A1 (en) 2013-02-06
US20060161208A1 (en) 2006-07-20
EP1846098A2 (en) 2007-10-24
EP2554216B1 (en) 2014-03-26
US7672724B2 (en) 2010-03-02
EP1846098B1 (en) 2015-04-22
US20100137932A1 (en) 2010-06-03
US8805503B2 (en) 2014-08-12

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