JP5025094B2 - Method for producing externally applied drug - Google Patents

Description

The present invention relates to a method for producing an externally applied drug for the purpose of preventing skin aging and moisturizing by combining a honeycomb residue after centrifugation, which has not been conventionally used, with an eggplant component and / or apple vinegar.

  Traditionally, honey has a pharmacological effect, and its medicinal effect is the oldest prescription on the slab of northern Samaria, northern Palestine, circa 2000 BC. Even in the West, it is a natural medicine for gastrointestinal weakness, stomatitis, cuts, etc It is used as. In Chinese medicine, honey is used to moisturize the lungs, stop coughing, moisten the intestines, constipation, stomach pain, stomatitis, burns, and so on.

  However, as a prescription method, it is generally used as a nourishing tonic combined with other internal medicines such as limonade and other herbal medicines, and it is only used for skin cream etc. for external use, and the honey component ratio Therefore, an effective method for maintaining skin health and preventing aging has not been found. If you apply honey directly to the skin, the effect may be expected, but if the ingredient ratio is high, the stickiness is strong, but if you reduce the ingredient ratio, it takes time to take effect without fixing to the skin End up.

  As described in Patent Document 1, honey can be used as a hypoallergenic external preparation in combination with glucan, but this is a recipe that must use glucan.

For the production of glucan having a cyclic structure in the example of Patent Document 1, commercially available waxy corn starch is suspended in a sodium phosphate buffer (about PH7), gelatinized by heating, allowed to cool, and then action reaction of branching enzyme After the completion, a complicated process of deactivating and removing the branching enzyme by heating, desalting and decoloring, and drying to obtain a powdered cyclic glucan is necessary.
Publication of Patent Application 2002-31831

  Honey that is expected to have a great effect on the skin can be expected to be effective when placed in a bath, but when mixed with hot water in the bath, the effect cannot be expected unless it is added in a large amount, which is not realistic.

  On the other hand, it is not practical to apply honey directly to the skin for the purpose of reducing the amount of use, because honey has a stickiness to the skin.

  Therefore, the present invention is intended to solve the problem by using the minimum amount of honey (concentrated honey) that can be expected to be effective as a transdermal drug, and also, as if it was put in a bath, it brings out an effect that lasts for a long time. The challenge is to maintain health and prevent aging.

The beehive is divided into honey and residue, for example by centrifugation, and this residue is heated and dissolved, then cooled and separated into wax and concentrated honey, and this concentrated honey , crushed dried coconut skin powder, and natural straw powder are mortared. The mixture is pulverized and mixed in hot water to form an aqueous solution.This aqueous solution is contained in a dry towel, and the aqueous solution is applied to the whole body and dried without wiping. I decided to use it as an external application medicine. The bees used as the material may be either Japanese bees or Western bees, but Japanese bees are preferred.

The external coating agent used in the coating method of the present invention removes active oxygen by β-carotene contained in honey and prevents wrinkles and rough skin. Specifically, it is effective in improving physical fitness and bleaching the skin. It is an externally harmless application for human beings that uses only pure plant components, does not use chemicals, etc., and produces a nutrient-rich high sugar concentration and strong antibacterial material at an optimal dilution rate.

Moreover, the external application | coating agent used with the application | coating method of this invention prevents skin aging by the pantothenic acid contained in honey. Specifically, it is effective for nails, reverse peeling, senile kayumi, herpes zoster pain, nose and eye itch, athlete's foot kayumi, vitality enhancement, footbath, etc.

Topical liniments used in the coating method of the present invention, by containing the skin citron, the effect of bark extract contained as a component, has a moisturizing, further external coating agent used in the coating method of the present invention, Pinerin acid contained in the skin of citrus by limonene re Naroru the effect of promoting blood circulation.

  Moreover, when apple cider vinegar is selected instead of eggplant as an additive component combined with concentrated honey, it is effective in removing skin spots and dullness, and is also effective in Kayumi.

  As an Example, the example of the external application | coating agent which contains the concentrated honey 1, the coconut skin 2, and the natural cocoon powder 3 as a component is demonstrated.

  First, 35 g of concentrated honey 1, 1 g of dried powder of coconut skin 2 and 150 g of natural cocoon powder 3 are pulverized and mixed in a mortar or a container having an equivalent function, and then dissolved in a dissolution medium (300 to 500 cc of hot water, An aqueous solution is preferably prepared by dissolving in 350 cc hot water).

  The aqueous solution is contained in a dry towel or the like, and the aqueous solution is applied to the application target site, for example, after wiping off moisture at the time of taking a bath, from the top of the body to the toes. Also, if you wash your face, you have a bleaching effect. This agent is not taken, but it gives nutrition and antibacterial properties to weak skin, promotes healing ability, and activates an enzyme that promotes tissue regeneration, thereby synergizing nutrition, healing, and vitality. It is a product. Therefore, it is desirable to wait for the coating solution to dry before taking clothes after applying the whole body of this agent as much as possible.

  The natural cocoon powder 3 is used for the purpose of retaining the components of the concentrated nectar 1 and the coconut skin 2, and is not limited to the natural cocoon powder 3 in particular. May be.

  Moreover, there exists an external application | coating agent which contains the apple vinegar 7 in the said concentrated honey 1 as an additional component as another Example. This has the effect of reducing skin spots and dullness, and is also effective for Kayumi.

  As a production method, first, a mixed solution 4 of concentrated honey 1 and apple cider vinegar 2 is prepared, and then diluted with water. At this time, since the concentrated honey 1 has a high viscosity at room temperature, it can be considered that the mixture 4 is mixed with the apple vinegar 7 heated to the same temperature at the stage where the viscosity is lowered by heating. Since the mixture 4 has a high concentration and is too strong to be applied directly to the skin or the like, it is desirable to apply an aqueous solution 5 of diluted water diluted with water (preferably lotion) before application to the skin or the like. .

  The mixing ratio for producing the diluted water solution 5 is preferably a ratio of concentrated honey: apple vinegar: water = 0.5 to 1.5: 1.5 to 2.5: 1.5 to 2.5. There are other benefits than this mixing ratio.

  Furthermore, the external application agent which uses together the said Example 1 and Example 2 and contains the coconut husk 2 and the apple vinegar 7 as an additional component to the said concentrated honey 1 is also considered.

The above-mentioned component combinations and effects in Examples 1 to 3 are shown in [Table 1].
Summarized in

  Concentrated nectar 1, coconut skin 2, and / or apple vinegar 7 are essential, but there is no problem in mixing with other components, and there is an effect other than the above mixing ratio.

  In the field of elderly care in an aging society, it is essential to increase the demand for simple and inexpensive health management methods. By using the external application agent of the invention of the present application, for example, for the care of a bedridden elderly person, simply by applying the external application agent of the invention of the present invention contained in a towel etc. Skin treatment is also possible. The external application agent of the present invention using honeycomb residue and coconut vinegar and / or apple vinegar has great ecological advantages and can be used as a health care aid for not only bedridden elderly people but also for all.

Example of manufacturing process of the external coating agent of the present invention Example of manufacturing process in another embodiment of the present invention

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Concentrated honey 2 ... Coconut skin 3 ... Natural powder 4 ... Mixture 5 ... Aqueous solution 6 ... Towel 7 ... Apple cider vinegar

Claims (1)

A method for producing a topical application drug comprising a honey component containing pantothenic acid and an eggplant component containing limonene and linalool and a natural strawberry powder component, wherein the honey component is concentrated nectar, and the concentrated nectar converts the honeycomb into honey and residue. divided, it cooled after heating dissolve the residue obtained in Rukoto allowed separated wax with concentrated honey, and concentrated molasses obtained, the dry powder of yuzu skin was pulverized, and ground and mixed wild yam powder in a mortar, A method for producing an externally applied drug, comprising dissolving in hot water to produce an aqueous solution.