JP4990763B2 - クモのドラグラインタンパク質、それを含む糸および材料、それをコードするベクター、ならびにクモのドラグラインタンパク質およびそれを含む糸の使用方法 - Google Patents

クモのドラグラインタンパク質、それを含む糸および材料、それをコードするベクター、ならびにクモのドラグラインタンパク質およびそれを含む糸の使用方法 Download PDF

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JP4990763B2
JP4990763B2 JP2007517202A JP2007517202A JP4990763B2 JP 4990763 B2 JP4990763 B2 JP 4990763B2 JP 2007517202 A JP2007517202 A JP 2007517202A JP 2007517202 A JP2007517202 A JP 2007517202A JP 4990763 B2 JP4990763 B2 JP 4990763B2
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protein
adf
spider
wound
substitute
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JP2008507260A (ja
JP2008507260A5 (enExample
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シャイベル、トーマス
ヒューメリッヒ、ダニエル
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アムシルク・ゲーエムベーハー
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    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • D01F4/02—Monocomponent artificial filaments or the like of proteins; Manufacture thereof from fibroin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Insects & Arthropods (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Textile Engineering (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Artificial Filaments (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2007517202A 2004-06-25 2005-06-23 クモのドラグラインタンパク質、それを含む糸および材料、それをコードするベクター、ならびにクモのドラグラインタンパク質およびそれを含む糸の使用方法 Expired - Lifetime JP4990763B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US58322704P 2004-06-25 2004-06-25
US60/583,227 2004-06-25
EP05005395.8 2005-03-11
EP05005395A EP1609801A1 (en) 2004-06-25 2005-03-11 Proteins of natural origin and materials made therefrom
PCT/EP2005/006799 WO2006002827A1 (en) 2004-06-25 2005-06-23 Proteins of natural origin and materials made therefrom

Publications (3)

Publication Number Publication Date
JP2008507260A JP2008507260A (ja) 2008-03-13
JP2008507260A5 JP2008507260A5 (enExample) 2012-05-17
JP4990763B2 true JP4990763B2 (ja) 2012-08-01

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JP2007517202A Expired - Lifetime JP4990763B2 (ja) 2004-06-25 2005-06-23 クモのドラグラインタンパク質、それを含む糸および材料、それをコードするベクター、ならびにクモのドラグラインタンパク質およびそれを含む糸の使用方法

Country Status (5)

Country Link
US (2) US8097583B2 (enExample)
EP (3) EP1609801A1 (enExample)
JP (1) JP4990763B2 (enExample)
CN (1) CN101133080A (enExample)
WO (2) WO2006002827A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1609801A1 (en) * 2004-06-25 2005-12-28 Technische Universität München Proteins of natural origin and materials made therefrom
DE102005043609A1 (de) 2005-09-13 2007-03-22 Technische Universität München Verfahren und Vorrichtung zur Herstellung eines Fadens aus Seidenproteinen
AU2006333611B2 (en) 2005-12-30 2012-04-26 Spiber Technologies Ab Spider silk proteins and methods for producing spider silk proteins
WO2007141131A1 (en) * 2006-06-08 2007-12-13 Technische Universitaet Muenchen Microfluidic device for controlled aggregation of spider silk
DE102006038445A1 (de) * 2006-08-16 2008-02-21 Gustav Pirazzi & Comp. Kg Verwendung von künstlich hergestellter Spinnenseide
US8975073B2 (en) 2006-11-21 2015-03-10 The Charles Stark Draper Laboratory, Inc. Microfluidic device comprising silk films coupled to form a microchannel
DE102007002222A1 (de) * 2007-01-10 2008-07-17 Gustav Pirazzi & Comp. Kg Verwendung von künstlich hergestellter Spinnenseide
WO2008155304A1 (de) * 2007-06-20 2008-12-24 Basf Se Synthetische repetitive proteine, deren herstellung und verwendung
CN102812036B (zh) * 2009-08-26 2016-08-03 联邦科学工业研究组织 用于生产丝纺丝液的方法
US9217017B2 (en) 2009-12-08 2015-12-22 Amsilk Gmbh Silk protein coatings
CA2795541C (en) * 2010-04-12 2020-05-26 Spiber Technologies Ab Spider silk protein scaffolds for eukaryotic cell culture
DE202013003445U1 (de) 2012-04-11 2013-04-26 Amsilk Gmbh Staubbeutel
US10478520B2 (en) 2012-08-17 2019-11-19 Amsilk Gmbh Use of self-assembling polypeptides as tissue adhesives
JP6450680B2 (ja) * 2012-09-06 2019-01-09 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法
WO2014062134A1 (en) 2012-10-17 2014-04-24 Nanyang Technological University Compounds and methods for the production of suckerin and uses thereof
EP2940066B1 (en) 2012-12-26 2020-02-05 Spiber Inc. Spider silk protein film, and method for producing same
EP3000125A4 (en) 2013-05-22 2017-02-08 Transient Electronics, Inc. Controlled transformation of non-transient electronics
WO2015061079A1 (en) 2013-10-21 2015-04-30 The North Face Apparel Corp. Functional biomaterial coatings for textiles and other substrates
US9394355B2 (en) 2014-08-20 2016-07-19 Silk Technologies, Ltd. Fibroin-derived protein composition
CN108290935A (zh) * 2015-08-10 2018-07-17 赛威克斯材料科学公司 用于制造合成的拖丝蜘蛛丝的组合物和方法
EP3395860A4 (en) 2015-12-25 2019-05-29 Spiber Inc. METHOD FOR PRODUCING A POLYMER AGGREGATE
AU2017218794B2 (en) * 2016-02-11 2021-07-22 Seevix Material Sciences Ltd. Composite materials comprising synthetic dragline spider silk
US10953132B2 (en) 2016-04-08 2021-03-23 Cornell University Method to enhance wound healing using silk-derived protein
US20190233481A1 (en) 2016-06-23 2019-08-01 Spiber Inc. Modified Fibroin
AU2017310520A1 (en) 2016-08-12 2019-03-21 Silk Technologies, Ltd. Silk-derived protein for treating inflammation
US20180096033A1 (en) * 2016-10-04 2018-04-05 International Business Machines Corporation Query management in database management systems
WO2018087239A1 (en) 2016-11-11 2018-05-17 Amsilk Gmbh Use of a shrinkable biopolymer fiber as sensor
DE102016222480B4 (de) 2016-11-16 2020-02-13 Adidas Ag Bekleidungsstück, das Spinnenseide aufweist oder Schuh, der Spinnenseide aufweist, und ein entsprechendes Herstellungsverfahren
WO2018229341A1 (en) * 2017-06-13 2018-12-20 Aalto University Foundation Sr. Method for producing a condensed adhesive phase of silk fusion proteins
WO2019194263A1 (ja) * 2018-04-03 2019-10-10 Ｓｐｉｂｅｒ株式会社 高収縮人造フィブロイン撚糸及びその製造方法、並びに人造フィブロイン撚糸及びその収縮方法
EP3556914A1 (de) 2018-04-20 2019-10-23 Lenzing Aktiengesellschaft Regenerierte cellulosische formkörper und verfahren zur herstellung regenerierter cellulosischer formkörper
MX2021000041A (es) * 2018-06-22 2021-03-25 Natura Cosmeticos Sa Composicion cosmetica para tratamiento de fibras de queratina.
AU2021259692A1 (en) 2020-04-23 2022-10-27 Seevix Material Sciences Ltd. Cosmetic compositions comprising dragline spider silk
TWI911309B (zh) 2020-10-20 2026-01-11 喬治 史特勞赫 包覆之毛髮及其用途
CN112680884A (zh) * 2020-12-30 2021-04-20 苏州经贸职业技术学院 一种抗菌口罩材料的制备方法
CN116446064B (zh) * 2022-12-29 2025-04-04 宜宾惠美纤维新材料股份有限公司 一种蛹虫草蛋白纤维及其制备方法

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US5994099A (en) 1997-12-31 1999-11-30 The University Of Wyoming Extremely elastic spider silk protein and DNA coding therefor
FR2774588B1 (fr) 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
US7157615B2 (en) 1998-03-17 2007-01-02 Nexia Biotechnologies, Inc. Production of biofilaments in transgenic animals
WO2003020916A2 (en) 2001-08-29 2003-03-13 University Of Wyoming Spider silk protein encoding nucleic acids, polypeptides, antibodies and method of use thereof
WO2003060099A2 (en) * 2002-01-11 2003-07-24 Nexia Biotechnologies, Inc. Methods and apparatus for spinning spider silk protein
US20070260039A1 (en) * 2002-01-11 2007-11-08 Karatzas Costas N Methods of Producing Silk Polypeptides and Products Thereof
EP1609801A1 (en) * 2004-06-25 2005-12-28 Technische Universität München Proteins of natural origin and materials made therefrom
ES2525095T3 (es) * 2004-07-22 2014-12-17 Amsilk Gmbh Proteínas recombinantes de la seda de araña

Also Published As

Publication number Publication date
CN101133080A (zh) 2008-02-27
WO2006002827A1 (en) 2006-01-12
WO2006002853A1 (en) 2006-01-12
JP2008507260A (ja) 2008-03-13
US8030024B2 (en) 2011-10-04
US20080021553A1 (en) 2008-01-24
EP1778722A1 (en) 2007-05-02
EP1609801A1 (en) 2005-12-28
EP1778849A1 (en) 2007-05-02
US8097583B2 (en) 2012-01-17
US20070196429A1 (en) 2007-08-23

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