JP4965801B2 - Yamabushitake extract powder and method for producing the same - Google Patents

Description

  The present invention relates to Yamabushitake extract powder and a method for producing the same.

Japanese Patent Laid-Open No. 5-117304 JP-A-6-256352 Japanese Patent Laid-Open No. 11-269088 JP-A-11-1438 JP 2003-2813 A

In recent years, the efficacy of Yamabushitake and its extract has been attracting attention. Patent Document 1 or 2 describes that it can be used as an antitumor agent, nerve growth factor production inducer, antibacterial agent, etc., and Patent Document 3 describes the amount of lipids in blood, particularly the amount of cholesterol, as a component of Yamabushitake. It is described that there is one having an action of lowering. Patent Document 4 describes that it can be used as an anti-aging agent for hair, skin or memory ability. Furthermore, Patent Document 5 describes a skin component as a specific effect for preventing skin aging. The protective, skin tension, elasticity recovery, maintenance, and their combined anti-wrinkle effects on the skin are described.
In order to easily absorb such an active ingredient of Yamabushitake into the body, it is conceivable to take a decocted fruit body. However, in order to fully take the active ingredient of Yamabushitake, it is necessary to take a large amount, which is troublesome.
Moreover, as a general industrial production method for ingesting active ingredients of mushrooms such as yamabushitake, as described in Patent Documents 1 to 3, the active ingredients are extracted from yamabushitake, and then concentrated and filled into capsules. Alternatively, it is known to mix with an excipient to form a dry powder and tablet or granulate. However, they are produced by extracting certain components, and not all the active ingredients of Yamabushitake are available, so it is clear whether the effects of Yamabushitake can be fully utilized. is not.

  It is an object of the present invention to provide a Yamabushitake extract powder that can ingest all the active ingredients of Yamabushitake into the body and efficiently absorb them.

Yamabushitake extract powder for improving the moisture retention of the skin of the present invention, Yamabushitake powder obtained by pulverizing dried fruit of Yamabushitake fruit body is extracted with alcohol at room temperature, and the residue is extracted with hot water at 90 to 96 degrees, all of the extract was freeze dried to those concentrated under reduced pressure, is characterized by that will be produced by pulverizing (claim 1). Moreover, what is said to be Yamabushitake cultivated by artificial cleaning cultivation is preferable (Claim 2).
The method for producing Yamabushitake extract powder of the present invention is a method for producing Yamabushitake extract powder for improving the moisture retention of the skin. The powder was extracted with alcohol at room temperature, the residue was extracted with hot water at 90 to 96 degrees, and all of the extract was concentrated under reduced pressure and freeze-dried and pulverized (claim 3). ).

Yamabushitake extract powder of the present invention is a Yamabushitake powder obtained by pulverizing the dried fruit of Yamabushitake fruit body at room temperature with alcohol, the residue is extracted with hot water of 90 to 96 degrees, and all of the extract is concentrated under reduced pressure. Because it is produced by freeze-drying and pulverizing the product, it has almost all components extracted from Yamabushitake with hot water. Therefore, all those components can be ingested, it is effective in skin wrinkle, high moisturizing effect on skin. Moreover, since the extract of Yamabushitake is separated from the raw material, the absorption by the extract in the body appears more effectively and remarkably. This is considered to be because the degree of absorption of the extract component into the body increases as a result of separation. Furthermore, it is thought that a synergistic effect is born by mixing the extract and the solid residue.

When such a Yamabushitake extract powder is cultivated by artificial clean cultivation, it is possible to use Yamabushitake having a large amount of any active ingredient depending on the application. Moreover, by cultivating under the same environment, it is possible to produce a large amount of Yamabushitake having substantially the same component content. This is because mushrooms such as Yamabushitake have completely different qualities depending on the growth place, the cultivation place, or their environmental conditions.
The Yamabushitake tablet product obtained by compressing any of the aforementioned Yamabushitake extract powder or the granulated Yamabushitake granule product is easy for the user to ingest the Yamabushitake component into the body.

According to the present invention, the extract of Yamabushitake is dried with hot air, and the dried product is pulverized to produce a Yamabushitake powder. The Yamabushitake powder is extracted with alcohol at room temperature, and the residue is heated at 90 to 96 degrees. Extracted with water, concentrated in vacuo, and freeze-dried and pulverized, so Yamabushitake extract powder with a high moisturizing effect on the skin, containing all the ingredients that Yamabushitake ingredients originally have Can be manufactured.

The harvested Yamabushitake fruiting body is dried with a hot air dryer, and the dried product is pulverized to produce a Yamabushitake powder. 75% (W / W) 2.6 times that of this Yamabushitake powder (raw material)
Add aqueous ethanol. This mixture is well suspended and suspended, and placed at room temperature for about 12 hours for alcohol extraction. Furthermore, water that is 20 times the amount of the raw material is added and stirred well to be suspended, and ethanol in the mixture is removed by a vacuum concentrator. Further, the mixture is heated with stirring and subjected to hot water extraction at 90 to 95 ° C. for about 2 hours to obtain a Yamabushitake extract. At this time, in addition to the extract (extract), Yamabushitake residue also remains in the Yamabushitake extract.
The Yamabushitake extract is concentrated under reduced pressure to 7 times the amount of the raw material using a vacuum concentrator. This concentrated solution (Yamabushitake extract + Yamabushitake residue) is pre-frozen, and then vacuum freeze-dried to an equal volume of the raw material by a vacuum freeze dryer and pulverized to obtain a Yamabushitake extract powder.

  This Yamabushitake extract powder is safe because it uses only Yamabushitake as a raw material without using excipients. And since all the Yamabushitake is used, it contains almost all the ingredients that the raw material of Yamabushake originally has. Moreover, the extract of Yamabushitake is extracted once and mixed with the residue again, so that the active ingredient of Yamabushitake is better absorbed by the body. Furthermore, because the extract of Yamabushitake of the present invention is produced by mixing the extract and the powder residue, the synergistic effect of these extracts makes the effect of ingesting in the body more than just ingesting Yamabushitake itself. Appear in

  Yamabushitake products are produced by tableting or granulating this powder. Since these products are molded from the Yamabushitake extract powder of the present invention, they are highly effective when taken into the body.

  As the fruit body of Yamabushitake, natural products or artificially grown products may be used. However, in the case of artificially produced Yamabushitake, it is possible to produce a large amount of Yamabushitake having substantially the same composition component, and therefore, there is little variation in product components. In particular, as artificially cleaned cultivated Yamabushitake, those containing 1.0 g / 100 g or more of β-D-glucan are preferable.

[Example 1]
Artificial clean cultivated Yamabushitake is dried, and 40 kg of pulverized Yamabushitake powder (raw material) and 104 kg of 75% (W / W) ethanol aqueous solution are filled in the extraction tank, and the raw material and the solvent are well suspended while stirring. This mixture was left to stand for 12 hours or more at room temperature. Thereafter, 760 kg of water was added and stirred to suspend the mixture, and ethanol contained in the mixture was removed at about 40 ° C. using a vacuum concentrator. Thereafter, the mixture was heated to 90 ° C. with stirring in an extraction tank, and extracted with hot water at 90 to 95 ° C. for 2 hours. This Yamabushitake extract was reduced under reduced pressure to about 7 times the amount of the raw material at about 40 ° C. using a vacuum concentrator (concentrated solution 280 kg). Thereafter, it was pre-frozen, freeze-dried with a vacuum freeze dryer, and 40 kg of Yamabushitake extract powder was obtained with an atomizer grinder (see FIG. 1). This was designated Example 1.

[Comparative Example 1]
In the production method of Example 1, artificially cultivated Yamabushitake was dried, and Yamabushitake powder having a moisture content of 10% or less was used as Comparative Example 1.

[Comparative Example 2]
In the manufacturing method of Example 1, the liquid of the concentrate was used as Comparative Example 2.

Twelve test subjects each took 3 g of the powder of Example 1, 3 g of the powder of Comparative Example 1, and 25 cc of the extract of Comparative Example 2 (equivalent to 3 g of dried product) for 60 days once a day.
Moisturizing power (preservation), elasticity (bullet), shine (te), rough skin (skin), redness (red), smoothness (smooth), dullness (skin), makeup paste Shi) and swell (mu) were evaluated before taking. The criteria at that time are shown below, and the results are shown in Table 1.
3 points improved 2 points improved slightly 1 point no change 0 points slightly deteriorated -1 point deteriorated -2 points very deteriorated -3 points

  No subject complained of skin abnormalities during the study period. In addition, although individual differences were observed in these doses, as shown in Table 1, the most preferred evaluation was obtained for the Yamabushitake extract powder in which the extract and the residue were mixed. Also, in Comparative Examples 1 and 2, a better result was obtained when taking a dried product of Yamabushitake extract than taking the extract. This is considered that the active ingredient which is effective in the said item remains also in the Yamabushitake residue which extracted the extract. And it is thought that the synergistic effect by having extracted them once and mixed with the Yamabushitake extract powder which mixed the Yamabushitake extract and the Yamabushitake residue was considered.

It is a flowchart which shows the manufacturing method of the Yamabushitake extract powder of this invention.

Claims (3)

Yamabushitake powder obtained by pulverizing the dried fruit of Yamabushitake fruit body is extracted with alcohol at room temperature,
The residue is extracted with hot water of 90-96 degrees,
It was produced by freeze-drying and pulverizing all of the extract concentrated under reduced pressure.
Yamabushitake extract powder to enhance the moisture retention of the skin. The Yamabushitake extract powder according to Claim 1, wherein the Yamabushitake is Yamabushitake cultivated by artificial clean cultivation. A method of manufacturing a Hericium erinaceus Extraction powder to increase the moisture retention of the skin,
Yamabushitake is dried with hot air, and the dried product is pulverized to produce a Yamabushitake powder. The Yamabushitake powder is extracted with alcohol at room temperature, and the residue is extracted with hot water at 90 to 96 degrees. A method for producing Yamabushitake extract powder, which is obtained by freeze-drying, pulverizing and processing a product concentrated under reduced pressure.