JP4917441B2 - モダフィニル組成物 - Google Patents

モダフィニル組成物 Download PDF

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Publication number
JP4917441B2
JP4917441B2 JP2006552169A JP2006552169A JP4917441B2 JP 4917441 B2 JP4917441 B2 JP 4917441B2 JP 2006552169 A JP2006552169 A JP 2006552169A JP 2006552169 A JP2006552169 A JP 2006552169A JP 4917441 B2 JP4917441 B2 JP 4917441B2
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JP
Japan
Prior art keywords
modafinil
degrees
percent
theta
pxrd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2006552169A
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English (en)
Japanese (ja)
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JP2007522147A (ja
JP2007522147A5 (enExample
Inventor
ブールゴール，ヒツキー・マガリ
ピーターソン，マシユー
アルマーソン，オルン
オリベイラ，マーク
Original Assignee
セフアロン・インコーポレーテツド
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Publication date
Priority claimed from PCT/US2004/029013 external-priority patent/WO2005023198A2/en
Application filed by セフアロン・インコーポレーテツド filed Critical セフアロン・インコーポレーテツド
Publication of JP2007522147A publication Critical patent/JP2007522147A/ja
Publication of JP2007522147A5 publication Critical patent/JP2007522147A5/ja
Application granted granted Critical
Publication of JP4917441B2 publication Critical patent/JP4917441B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
JP2006552169A 2004-02-06 2005-02-01 モダフィニル組成物 Expired - Fee Related JP4917441B2 (ja)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US54275204P 2004-02-06 2004-02-06
US60/542,752 2004-02-06
US56041104P 2004-04-06 2004-04-06
US60/560,411 2004-04-06
US57341204P 2004-05-21 2004-05-21
US60/573,412 2004-05-21
US57917604P 2004-06-12 2004-06-12
US60/579,176 2004-06-12
US58199204P 2004-06-22 2004-06-22
US60/581,992 2004-06-22
US58675204P 2004-07-09 2004-07-09
US60/586,752 2004-07-09
US58823604P 2004-07-15 2004-07-15
US60/588,236 2004-07-15
USPCT/US04/29013 2004-09-04
PCT/US2004/029013 WO2005023198A2 (en) 2003-09-04 2004-09-04 Modafinil compositions
US63178604P 2004-11-30 2004-11-30
US60/631,786 2004-11-30
PCT/US2005/002782 WO2005077894A1 (en) 2004-02-06 2005-02-01 Modafinil compositions

Publications (3)

Publication Number Publication Date
JP2007522147A JP2007522147A (ja) 2007-08-09
JP2007522147A5 JP2007522147A5 (enExample) 2008-03-06
JP4917441B2 true JP4917441B2 (ja) 2012-04-18

Family

ID=38456572

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006552169A Expired - Fee Related JP4917441B2 (ja) 2004-02-06 2005-02-01 モダフィニル組成物

Country Status (7)

Country Link
EP (1) EP1718607A4 (enExample)
JP (1) JP4917441B2 (enExample)
AU (1) AU2005212229B2 (enExample)
CA (1) CA2556106A1 (enExample)
EA (1) EA009949B1 (enExample)
IL (1) IL176934A (enExample)
WO (1) WO2005077894A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050025791A1 (en) 2002-06-21 2005-02-03 Julius Remenar Pharmaceutical compositions with improved dissolution
JP4906233B2 (ja) 2002-03-01 2012-03-28 ユニバーシティー オブ サウス フロリダ 少なくとも１種の有効薬剤成分を含有する多構成要素固相
FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
WO2005099822A2 (en) * 2004-04-13 2005-10-27 Cephalon, Inc. Reduction of drug / drug interactions with modafinil
WO2007062147A1 (en) * 2005-11-22 2007-05-31 Teva Pharmaceutical Industries Ltd. Crystal forms of cinacalcet hci and processes for their preparation
CN100343228C (zh) * 2006-02-17 2007-10-17 中国科学院上海有机化学研究所 高对映体选择性制备 2－二苯甲基亚磺酰基－乙酰胺单一对映体的方法
WO2007098273A2 (en) * 2006-02-21 2007-08-30 Teva Pharmaceutical Industries Ltd. Novel crystalline forms of armodafinil and preparation thereof
CA2688430A1 (en) * 2007-06-04 2008-12-11 Generics [Uk] Limited Novel process
US7960586B2 (en) 2007-08-16 2011-06-14 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
US20090105346A1 (en) * 2007-10-02 2009-04-23 Alexandr Jegorov Novel crystalline forms of armodafinil and preparation thereof
WO2009090663A1 (en) * 2008-01-15 2009-07-23 Lupin Limited Novel crystalline polymorph of armodafinil and an improved process for preparation thereof
KR102126389B1 (ko) * 2018-09-14 2020-06-25 셀라이온바이오메드 주식회사 벤즈히드릴티오 아세트아미드 화합물을 유효성분으로 포함하는 간 질환의 예방 또는 치료용 조성물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62190160A (ja) * 1986-01-31 1987-08-20 ラボラトワ−ル　エル　ラフオン （−）−ベンツヒドリルスルフイニルアセトアミド及びその製法
JP2003521487A (ja) * 2000-01-31 2003-07-15 ラボラトワール エル．ラフォン ミオパシー関連性の覚醒障害を矯正することが意図される医薬品を製造するためのモダフィニルの使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101081212B1 (ko) * 2000-07-27 2011-11-07 테바 파마슈티컬 인더스트리즈 리미티드 결정질의 순수한 모다피닐 및 이의 제조 방법
FR2849029B1 (fr) * 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62190160A (ja) * 1986-01-31 1987-08-20 ラボラトワ−ル　エル　ラフオン （−）−ベンツヒドリルスルフイニルアセトアミド及びその製法
JP2003521487A (ja) * 2000-01-31 2003-07-15 ラボラトワール エル．ラフォン ミオパシー関連性の覚醒障害を矯正することが意図される医薬品を製造するためのモダフィニルの使用

Also Published As

Publication number Publication date
EA200601390A1 (ru) 2006-12-29
EP1718607A1 (en) 2006-11-08
AU2005212229A1 (en) 2005-08-25
JP2007522147A (ja) 2007-08-09
EA009949B1 (ru) 2008-04-28
IL176934A0 (en) 2006-12-10
AU2005212229B2 (en) 2011-06-09
CA2556106A1 (en) 2005-08-25
EP1718607A4 (en) 2008-05-28
IL176934A (en) 2013-06-27
WO2005077894A1 (en) 2005-08-25

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