JP4887475B2 - 自己蛍光を除去するために複数の検出チャネルを使用するシステム及び方法 - Google Patents

自己蛍光を除去するために複数の検出チャネルを使用するシステム及び方法 Download PDF

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JP4887475B2
JP4887475B2 JP2007319724A JP2007319724A JP4887475B2 JP 4887475 B2 JP4887475 B2 JP 4887475B2 JP 2007319724 A JP2007319724 A JP 2007319724A JP 2007319724 A JP2007319724 A JP 2007319724A JP 4887475 B2 JP4887475 B2 JP 4887475B2
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channel
light
value
sample
signal
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JP2008151784A (ja
JP2008151784A5 (enExample
Inventor
ティー クリヴァシック ロバート
ベン シエー エイチ
エヌ カリー ダグラス
エイチ ブルース リチャード
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SRI International Inc
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SRI International Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/08—Optical fibres; light guides
    • G01N2201/0833—Fibre array at detector, resolving

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2007319724A 2006-12-18 2007-12-11 自己蛍光を除去するために複数の検出チャネルを使用するシステム及び方法 Expired - Fee Related JP4887475B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/612,228 US7545498B2 (en) 2006-12-18 2006-12-18 System and method for removing auto-fluorescence through the use of multiple detection channels
US11/612,228 2006-12-18

Publications (3)

Publication Number Publication Date
JP2008151784A JP2008151784A (ja) 2008-07-03
JP2008151784A5 JP2008151784A5 (enExample) 2011-03-03
JP4887475B2 true JP4887475B2 (ja) 2012-02-29

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JP2007319724A Expired - Fee Related JP4887475B2 (ja) 2006-12-18 2007-12-11 自己蛍光を除去するために複数の検出チャネルを使用するシステム及び方法

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US (1) US7545498B2 (enExample)
EP (1) EP1936359A3 (enExample)
JP (1) JP4887475B2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103765483B (zh) * 2011-08-25 2016-02-10 光荣株式会社 纸张识别装置
US10147180B2 (en) 2013-12-19 2018-12-04 Axon Dx, Llc Cell detection, capture and isolation methods and apparatus
JP6291972B2 (ja) * 2014-03-31 2018-03-14 三菱マテリアル株式会社 サンプリング位置表示装置、サンプリング方法
DE102020216541A1 (de) 2020-12-23 2022-06-23 Robert Bosch Gesellschaft mit beschränkter Haftung Vorrichtung und Verfahren für eine Fluoreszenzmessung für eine Analyse einer biochemischen Probe

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US1875904A (en) 1930-09-13 1932-09-06 Andrew C Wood Fluid pump
JPH03152444A (ja) * 1989-11-10 1991-06-28 Kirin Brewery Co Ltd 微生物の検出法および検出装置
US5480804A (en) * 1989-06-28 1996-01-02 Kirin Beverage Corporation Method of and apparatus for detecting microorganisms
JPH08334466A (ja) 1995-06-06 1996-12-17 Nikon Corp 蛍光測光方法及び装置
JPH1194743A (ja) * 1997-09-18 1999-04-09 Hitachi Software Eng Co Ltd 蛍光パターン読み取り装置
US7113624B2 (en) * 2002-10-15 2006-09-26 Palo Alto Research Center Incorporated Imaging apparatus and method employing a large linear aperture
US20040259270A1 (en) * 2003-06-19 2004-12-23 Wolf David E. System, device and method for exciting a sensor and detecting analyte
US7418507B2 (en) * 2003-12-18 2008-08-26 Microsoft Corporation Virtual resource serving of consolidated server shares
US7280261B2 (en) * 2004-12-20 2007-10-09 Palo Alto Research Center Incorporated Method of scanning and light collection for a rare cell detector
US7286224B2 (en) * 2004-12-21 2007-10-23 Palo Alto Research Center Incorporated Time-multiplexed scanning light source for multi-probe, multi-laser fluorescence detection systems

Also Published As

Publication number Publication date
JP2008151784A (ja) 2008-07-03
US20080144009A1 (en) 2008-06-19
EP1936359A3 (en) 2008-08-20
US7545498B2 (en) 2009-06-09
EP1936359A2 (en) 2008-06-25

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