JP4838239B2 - ニトロレダクターゼ酵素活性の測定法及び試薬 - Google Patents

ニトロレダクターゼ酵素活性の測定法及び試薬 Download PDF

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JP4838239B2
JP4838239B2 JP2007514089A JP2007514089A JP4838239B2 JP 4838239 B2 JP4838239 B2 JP 4838239B2 JP 2007514089 A JP2007514089 A JP 2007514089A JP 2007514089 A JP2007514089 A JP 2007514089A JP 4838239 B2 JP4838239 B2 JP 4838239B2
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group
groups
compound
methyl
nitroreductase
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JP2007514089A
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Japanese (ja)
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JP2008500828A5 (https=
JP2008500828A (ja
Inventor
ウエスト，リチャード・マーティン
イスメイル，ラーマン
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ジーイー・ヘルスケア・ユーケイ・リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C09B57/007—Squaraine dyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2007514089A 2004-05-28 2005-05-24 ニトロレダクターゼ酵素活性の測定法及び試薬 Expired - Fee Related JP4838239B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0411993.9 2004-05-28
GBGB0411993.9A GB0411993D0 (en) 2004-05-28 2004-05-28 Method and reagent for measuring nitroreductase enzyme activity
PCT/GB2005/002057 WO2005118839A1 (en) 2004-05-28 2005-05-24 Method and reagent for measuring nitroreductase enzyme activity

Publications (3)

Publication Number Publication Date
JP2008500828A JP2008500828A (ja) 2008-01-17
JP2008500828A5 JP2008500828A5 (https=) 2008-07-03
JP4838239B2 true JP4838239B2 (ja) 2011-12-14

Family

ID=32671256

Family Applications (1)

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JP2007514089A Expired - Fee Related JP4838239B2 (ja) 2004-05-28 2005-05-24 ニトロレダクターゼ酵素活性の測定法及び試薬

Country Status (10)

Country Link
US (2) US7579140B2 (https=)
EP (1) EP1749103B1 (https=)
JP (1) JP4838239B2 (https=)
CN (1) CN1993477A (https=)
AT (1) ATE553215T1 (https=)
AU (1) AU2005250209B2 (https=)
CA (2) CA2778894C (https=)
GB (1) GB0411993D0 (https=)
NZ (2) NZ551506A (https=)
WO (1) WO2005118839A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7767834B2 (en) 2004-08-13 2010-08-03 Elitech Holding B.V. Phosphonylated fluorescent dyes and conjugates
EP1781675B1 (en) 2004-08-13 2014-03-26 Epoch Biosciences, Inc. Phosphonate fluorescent dyes and conjugates
GB0505777D0 (en) * 2005-03-22 2005-04-27 Amersham Biosciences Uk Ltd Enzyme detection method and reagent
GB0800938D0 (en) 2008-01-18 2008-02-27 Ge Healthcare Uk Ltd Multiplex cell signalling assay
WO2010151592A1 (en) * 2009-06-23 2010-12-29 Bayer Healthcare Llc System and apparatus for determining temperatures in a fluid analyte system
JP5535664B2 (ja) * 2010-01-15 2014-07-02 株式会社Ａｄｅｋａ 色調補正剤、スクアリリウム化合物及び光学フィルター
US8828678B2 (en) 2010-11-16 2014-09-09 Enzo Life Sciences, Inc. Self-immolative probes for enzyme activity detection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07160028A (ja) * 1993-09-27 1995-06-23 Eastman Kodak Co 電子写真要素および電子写真方法
JP2000508709A (ja) * 1996-04-19 2000-07-11 アマーシャム・ファルマシア・バイオテック・ユーケイ・リミテッド スクアラート染料類および蛍光配列決定法におけるそれらの使用
JP2003522333A (ja) * 2000-02-02 2003-07-22 アマシャム バイオサイエンス ユーケイ リミテッド 蛍光検出法および試薬
WO2003087052A2 (en) * 2002-04-10 2003-10-23 Terpetschnig Ewald A Dyes and fluorescent compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039818A (en) * 1986-02-27 1991-08-13 Syntex (U.S.A.) Inc. Squaraine dye
EP1196398A4 (en) 1999-07-06 2002-11-06 Surromed Inc BRIDGED FLUORESCENT DYES, THEIR PRODUCTION AND USE IN DETECTION METHODS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07160028A (ja) * 1993-09-27 1995-06-23 Eastman Kodak Co 電子写真要素および電子写真方法
JP2000508709A (ja) * 1996-04-19 2000-07-11 アマーシャム・ファルマシア・バイオテック・ユーケイ・リミテッド スクアラート染料類および蛍光配列決定法におけるそれらの使用
JP2003522333A (ja) * 2000-02-02 2003-07-22 アマシャム バイオサイエンス ユーケイ リミテッド 蛍光検出法および試薬
WO2003087052A2 (en) * 2002-04-10 2003-10-23 Terpetschnig Ewald A Dyes and fluorescent compounds

Also Published As

Publication number Publication date
EP1749103B1 (en) 2012-04-11
ATE553215T1 (de) 2012-04-15
US20080317674A1 (en) 2008-12-25
NZ551506A (en) 2010-04-30
CA2568754C (en) 2012-08-21
WO2005118839A1 (en) 2005-12-15
US7579140B2 (en) 2009-08-25
GB0411993D0 (en) 2004-06-30
AU2005250209B2 (en) 2009-07-30
JP2008500828A (ja) 2008-01-17
EP1749103A1 (en) 2007-02-07
US20090325209A1 (en) 2009-12-31
CA2778894A1 (en) 2005-12-15
CN1993477A (zh) 2007-07-04
CA2778894C (en) 2013-12-31
US8378120B2 (en) 2013-02-19
AU2005250209A1 (en) 2005-12-15
NZ583956A (en) 2011-08-26
CA2568754A1 (en) 2005-12-15

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