JP4804598B2 - 骨の成長を刺激する繊維芽細胞成長因子の使用 - Google Patents

骨の成長を刺激する繊維芽細胞成長因子の使用 Download PDF

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JP4804598B2
JP4804598B2 JP53662196A JP53662196A JP4804598B2 JP 4804598 B2 JP4804598 B2 JP 4804598B2 JP 53662196 A JP53662196 A JP 53662196A JP 53662196 A JP53662196 A JP 53662196A JP 4804598 B2 JP4804598 B2 JP 4804598B2
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JPH11506446A5 (enExample
JPH11506446A (ja
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コリン アール ダンスタン
エリズビータ イズビッカー
グレゴリー マンディー
ウィルソン バージェス
マイケル シー ジェイエ
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アベンティス・ファーマスーティカルズ・インコーポレイテツド
オステオサ インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
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    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • C07K14/501Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
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    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10S530/827Proteins from mammals or birds
    • Y10S530/84Bones; tendons; teeth; cartilage

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP53662196A 1995-05-31 1996-05-29 骨の成長を刺激する繊維芽細胞成長因子の使用 Expired - Fee Related JP4804598B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/454,964 US5656598A (en) 1994-03-08 1995-05-31 Use of fibroblast growth factors to stimulate bone growth
US08/454,964 1995-05-31
PCT/US1996/007920 WO1996038167A1 (en) 1995-05-31 1996-05-29 Use of fibroblast growth factors to stimulate bone growth

Publications (3)

Publication Number Publication Date
JPH11506446A JPH11506446A (ja) 1999-06-08
JPH11506446A5 JPH11506446A5 (enExample) 2004-09-02
JP4804598B2 true JP4804598B2 (ja) 2011-11-02

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JP53662196A Expired - Fee Related JP4804598B2 (ja) 1995-05-31 1996-05-29 骨の成長を刺激する繊維芽細胞成長因子の使用

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US (1) US5656598A (enExample)
EP (1) EP0830138B1 (enExample)
JP (1) JP4804598B2 (enExample)
AT (1) ATE295734T1 (enExample)
AU (1) AU696460B2 (enExample)
CA (1) CA2222217C (enExample)
DE (1) DE69634748D1 (enExample)
WO (1) WO1996038167A1 (enExample)

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US9585916B2 (en) 1999-03-26 2017-03-07 Northern Therapeutics Inc. Cell based therapy for the pulmonary system
US20030118567A1 (en) * 1999-03-26 2003-06-26 Stewart Duncan John Cell-based therapy for the pulmonary system
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US5929051A (en) * 1998-05-13 1999-07-27 Carrington Laboratories, Inc. Aloe pectins
US6313103B1 (en) 1998-05-13 2001-11-06 Carrington Laboratories, Inc. Pectic substance as a growth factor stabilizer
US6916783B2 (en) * 1998-07-13 2005-07-12 University Of Southern California Methods for accelerating bone and cartilage growth and repair
EP1094829B8 (en) 1998-07-13 2004-09-22 University Of Southern California Methods for accelerating bone and cartilage growth and repair
US6551355B1 (en) 1998-08-14 2003-04-22 Cambridge Scientific, Inc. Tissue transplant coated with biocompatible biodegradable polymer
WO2000015273A1 (de) * 1998-09-11 2000-03-23 Gerhard Schmidmaier Biologisch aktive implantate
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US6231528B1 (en) 1999-01-15 2001-05-15 Jonathan J. Kaufman Ultrasonic and growth factor bone-therapy: apparatus and method
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CA2222217C (en) 2010-09-14
DE69634748D1 (de) 2005-06-23
WO1996038167A1 (en) 1996-12-05
EP0830138A1 (en) 1998-03-25
EP0830138A4 (en) 2000-10-25
AU696460B2 (en) 1998-09-10
ATE295734T1 (de) 2005-06-15
EP0830138B1 (en) 2005-05-18
JPH11506446A (ja) 1999-06-08
AU6146496A (en) 1996-12-18
US5656598A (en) 1997-08-12
CA2222217A1 (en) 1996-12-05

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