JP4801424B2 - Deodorant composition for cosmetics - Google Patents

Description

  There are two types of sweat glands in the human body: eccrine sweat glands and apocrine sweat glands. Apocrine sweat glands are present in limited areas such as the axilla, anal, and areola. The apocrine sweat glands are affected by hormones and become more functional from puberty and increase the secretion of apocrine sweat. This apocrine sweat gives off a unique smell by being decomposed by bacteria on the skin surface. These body odors cause discomfort to those around you, and those with strong body odors are mentally stressed. The present invention relates to a deodorant composition for cosmetics intended to prevent the generation of body odor.

  There have been many products intended to prevent or reduce body odor, and many of these products usually contain antiperspirants, bactericides, masking agents for odorous components, adsorbents, and the like. The above antiperspirants suppress the amount of sweating, and as such antiperspirants, most are aluminum compounds, and aluminum chloride is usually used. Moreover, the said bactericidal agent suppresses the growth of microorganisms causing aside, and as such a bactericidal agent, hexachlorophene and various quaternary ammonium compounds are used. In addition, as a masking agent for the odorous component, a substance having a pleasant odor such as eugenol is used. Furthermore, zinc oxide, activated carbon, zeolite, or the like is used as the adsorbent for the odorous component. (For example, refer to Patent Document 1.) In addition, attempts using corticosteroids (see, for example, Patent Document 2) focusing on steroid compound synthesis / secretion inhibitory action in biological tissues and attempts using glycyrrhizic acid (for example, Patent Document). 3) is also disclosed. A deodorizing cosmetic composition using a polyglycerin fatty acid ester such as diglycerin fatty acid ester is also disclosed. (For example, refer to Patent Document 4.)

JP-A-63-43665 (1-7 pages) JP-A-3-66608 (pages 1 to 3) JP-A-3-193727 (1-5 pages) Special table hei 8-502500 (pages 1-27)

  However, the above antiperspirant has an action of reducing sweat that causes body odor, but it is impossible to completely suppress sweating from a physiological point of view. , There is a drawback that the full effect cannot be expected. Moreover, the said bactericidal agent has pointed out the problem of safety, and there exists a fault that it cannot mix | blend with the density | concentration which fully expresses the effect. Moreover, the said masking agent has the fault that it mixes with a body odor and may generate | occur | produce an unpleasant odor on the contrary. The adsorbent has a drawback that it is highly effective for low-boiling components such as lower fatty acids but is not very effective for high-boiling components. In addition, when applied continuously, corticosteroids can be treated only temporarily because of side effects. In addition, polyglycerol fatty acid esters are susceptible to degradation by lipase produced by bacteria on the surface of the skin, and there is a problem that the effect may not be sustained. Furthermore, attempts to use glycyrrhizic acid are not practical because the effects are not sustained. Thus, the prior art has been extremely inadequate.

［但し、式中、Ｒは炭素数８〜１４のアルキル基で直鎖状又は分岐状であることを問わない、ｎは２〜１０の整数を表す。］により表される１種もしくは２種以上のアルキルポリグリセリルエーテルを含有することを特徴とする化粧料用消臭組成物である。 The present inventors have studied for the purpose of developing a deodorant composition for cosmetics that has a high deodorizing effect on the human body and has a high durability, and as a result, alkyl polyglyceryl ether is very effective for deodorizing the human body and has long-lasting properties. Found it expensive. That is, the present invention relates to the general formula (1)

[In the formula, R is an alkyl group having 8 to 14 carbon atoms, regardless of whether it is linear or branched, and n represents an integer of 2 to 10. ] The deodorizing composition for cosmetics characterized by containing the 1 type (s) or 2 or more types of alkyl polyglyceryl ether represented by these.

  Further, if necessary, these cosmetic deodorizing ingredients are used in combination with catechins known as deodorizing ingredients.

  By blending the deodorant composition for cosmetics of the present invention, an extremely excellent body odor prevention effect can be expected.

  Details of the present invention will be described below.

The alkylpolyglyceryl ether of the present invention has a specific structure represented by the general formula (1).
R in the general formula (1) is preferably a linear or branched alkyl group having 8 to 14 carbon atoms, particularly preferably a linear alkyl group having 8 to 12 carbon atoms. Preferable examples of such an alkyl group include octyl group, nonyl group, decyl group, undecyl group, dodecyl group, tridecyl group, and tetradecyl group. Further, n in the formula (1) is not particularly limited as long as it is an integer of 2 to 10, but is preferably 2 to 3 and more preferably 2 from the viewpoint of the deodorizing effect.

  As a method for producing polyglycerol monoalkyl ether, in the presence of a basic catalyst, a method in which glycidol is added to and reacted with an aliphatic alcohol so that the molar ratio of the alcohol / glycidol is specified; Examples thereof include a method of reacting an olefin epoxide, a method of opening a ring of alkyl glycidyl ether using polyglycerin in the presence of an acid catalyst or an alkali catalyst, but are not particularly limited. Preferred examples of such polyglycerin monoalkyl ether include tetraglycerin monooctyl ether, tetraglycerin monodecyl ether, tetraglycerin monododecyl ether, tetraglycerin monotetradecyl ether, triglycerin monooctyl ether, triglycerin monodecyl ether, Examples include triglycerin monododecyl ether, triglycerin monotetradecyl ether, diglycerin monooctyl ether, diglycerin monodecyl ether, diglycerin monododecyl ether, and more preferably diglycerin monododecyl ether, diglycerin monooctyl ether, Diglycerin monodecyl ether. The blending amount of the alkyl polyglyceryl ether of the present invention is preferably 0.01 to 10% by weight in the cosmetic.

  Specific examples of the catechins of the present invention include catechin, epicatechin, gallocatechin, catechin gallate, epicatechin gallate, gallocatechin gallate, epigallocatechin gallate, epigallocatechin and their derivatives, polymers and stereoisomers. 1 type, or 2 or more types of mixtures chosen from these are mention | raise | lifted. Either natural products or synthetic products can be used, but natural plant extracts that have been used so far are preferable in consideration of safety.

  As specific examples of plants, camellia plants such as tea, grape plants such as grapes, arabeaceae plants such as coffee, aogiriaceae plants such as cacao, capeaceae plants such as buckwheat, gooseberries, blackcurrants, redcurrants such as redcurrants Examples include plants, blueberries, white berries, black hackleberries, cranberries, strawberry tea, apples, etc. Depending on these plants, fruits, pericarps, flowers, leaves, stems, bark, roots, tuberous roots, seeds A site such as a seed coat is arbitrarily selected.

  Catechins can be extracted from these plants by a known method, for example, one or more solvents selected from hot water, ethyl acetate, methanol, ethanol, isopropanol and the like.

  Among them, catechins obtained by extraction from tea which is a camellia plant are preferable because they have a high deodorizing effect and various safetys are confirmed, and among them, those obtained using green tea as a raw material are preferable.

  As catechins obtained from tea, (+)-catechin, (+)-gallocatechin, (−)-gallocatechin gallate, (−)-epicatechin, (−)-epicatechin gallate, (−)-epigallo There exist catechin, (-)-epigallocatechin gallate, etc., and 1 type, or 2 or more types of mixtures chosen from these are mentioned.

  The method for obtaining a tea extract containing catechins is not particularly limited, for example, a fraction obtained by pulverizing tea leaves or tea leaves with water or hot water or alcohol such as glycerin or ethanol, Alternatively, it can be obtained from an ethyl acetate or acetone fraction obtained by adding ethyl acetate or acetone to a fraction extracted with water, hot water, or an alcohol such as glycerin or ethanol. Preferably, it is a method of obtaining tea leaves or tea leaves pulverized from ethyl acetate or acetone fractions obtained by adding ethyl acetate or acetone to a fraction extracted from water or hot water.

  Moreover, it does not specifically limit about the purity of the catechin in an extract, Preferably it is 40% or more, More preferably, it is 60% or more.

  Commercially available polyphenol-containing materials such as Sanphenon (manufactured by Taiyo Kagaku Co., Ltd.), Teafuran (manufactured by ITO EN Co., Ltd.), San Oolong (manufactured by Suntory Ltd.), polyphenon (manufactured by Tokyo Food Techno Co., Ltd.), etc. Although the compounding quantity of the catechin of this invention is not specifically limited, It is 0.001-1% in cosmetics, Preferably it is 0.01-0.1 weight%.

  When catechins are added to conventional cleaning compositions, it causes interaction, leading to precipitation, cloudiness, and a decrease in viscosity, and there are concerns about adverse effects on the final product. When catechins are blended, the emulsion stability is good and the deodorizing effect can be sufficiently exhibited.

  Examples of other preferable components to be blended in the cosmetic deodorant composition of the present invention include various body odor preventing components conventionally used in this type of product. For example, antiperspirants such as aluminum hydroxychloride, aluminum chloride, silver zeolite, aluminum sulfate, basic aluminum bromide, aluminum phenol sulfonic acid, tannic acid, aluminum naphthalene sulfonic acid, basic aluminum iodide, 2, 4, 4 Disinfectants such as' -trichloro-2'-hydroxydiphenyl ether, 3,4,4'-trichlorocarbanilide (TCC), benzalconium chloride, alkyltrimethylammonium chloride, resorcin, phenol, sorbic acid, salicylic acid, hexachlorophene, musk And masking agents such as skatole, lemon oil, lavender oil, absolute, jasmine, vanillin, benzoin, benzyl acetate, and menthol. Furthermore, the deodorant cosmetic composition of the present invention varies depending on the dosage form, but it contains oil, surfactant, water, alcohols, sugars, esters, preservatives, vitamin A, vitamin D, vitamin E, vitamin K. Such as vitamins, hormones such as estradiol and cortisone, anti-inflammatory agents such as allantoin, other moisturizers, thickeners, fragrances, pigments and the like can be appropriately blended within the range not impairing the effects of the present invention.

  Examples of the surfactant that can be used include nonionic surfactants, amphoteric surfactants, anionic surfactants, and cationic surfactants. The cosmetic deodorant composition of the present invention can be in the form of aerosol, roll-on, powder, cream, lotion, stick, solid detergent, liquid detergent, etc. 1-3 times a day It is used by leaving it as it is or washing it off, but it is not particularly limited thereto.

  Hereinafter, the present invention will be described more specifically with the results of clinical trials for patients with an actual side effect, but the present invention is not limited to such examples.

  The test patients were 10 volunteers. The catechins were tested using Sunphenon DK (catechin content 70% or more) manufactured by Taiyo Kagaku Co., Ltd.

  The aerosol spray which mix | blended with the ratio of LP gas 1 with respect to the undiluted | stock solution 9 obtained by mix | blending each raw material in the ratio of Examples 1-8 of Table 1 and Table 2, and Comparative Examples 1-4 was obtained.

  Aside from 10 patients, the products obtained in Examples 1 to 8 and Comparative Examples 1 to 4 were sprayed and applied for 1 second under the arm once a day by a normal method for evaluation the next day. The mode is marked with a circle, 5 points for no odor (4), 4 points for almost no odor, 3 points for a little odor, 2 points for a slightly better odor but better than usual 20 panelists evaluated that there was no score, the average value was calculated, and the results are shown in Table 3.

  Next, each raw material was mix | blended in the ratio of Examples 9-16 of Table 4 and Table 5, and Comparative Examples 5-8, and the W / O cream was obtained by the conventional method.

  For 10 patients on the side, 1 ml of the product obtained in Examples 9 to 16 and Comparative Examples 5 to 8 was applied once a day under a normal method for one week, and the next day was evaluated. The mode is marked with a circle, 5 points for no odor (4), 4 points for almost no odor, 3 points for a little odor, 2 points for a slightly better odor but better than usual The panel was evaluated by 20 panelists, and the average value was calculated. Table 6 shows the result.

  By blending the deodorant composition for cosmetics of the present invention, an extremely excellent body odor prevention effect was recognized.

Claims (2)

General formula

[In the formula, R is an alkyl group having 8 to 14 carbon atoms, regardless of whether it is linear or branched, and n represents an integer of 2 to 10. Deodorant composition for cosmetics, comprising at least one alkylpolyglyceryl ether selected from the group consisting of diglycerin monododecyl ether, triglycerin monododecyl ether and diglycerin monodecyl ether object. General formula

[In the formula, R is an alkyl group having 8 to 14 carbon atoms, regardless of whether it is linear or branched, and n represents an integer of 2 to 10. ] The deodorizing composition for cosmetics characterized by containing the 1 type, or 2 or more types of alkyl polyglyceryl ether and catechin represented by these.