JP4750416B2 - 副甲状腺ホルモン受容体の活性化と造血前駆細胞の増殖 - Google Patents

副甲状腺ホルモン受容体の活性化と造血前駆細胞の増殖 Download PDF

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JP4750416B2
JP4750416B2 JP2004524880A JP2004524880A JP4750416B2 JP 4750416 B2 JP4750416 B2 JP 4750416B2 JP 2004524880 A JP2004524880 A JP 2004524880A JP 2004524880 A JP2004524880 A JP 2004524880A JP 4750416 B2 JP4750416 B2 JP 4750416B2
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pth
cells
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hematopoietic progenitor
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エム カルヴィ,ローラ
ビー アダムス,グレガー
エム クローネンバーグ,ヘンリー
ティー スカッデン,デイヴィッド
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ザ ジェネラル ホスピタル コーポレイション
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
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    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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JP2004524880A 2002-07-25 2003-07-25 副甲状腺ホルモン受容体の活性化と造血前駆細胞の増殖 Expired - Fee Related JP4750416B2 (ja)

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US39880102P 2002-07-25 2002-07-25
US60/398,801 2002-07-25
PCT/US2003/023425 WO2004011484A2 (en) 2002-07-25 2003-07-25 Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion

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JP2006512897A JP2006512897A (ja) 2006-04-20
JP2006512897A5 JP2006512897A5 (enExample) 2007-10-04
JP4750416B2 true JP4750416B2 (ja) 2011-08-17

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US (2) US7429383B2 (enExample)
EP (1) EP1545603B1 (enExample)
JP (1) JP4750416B2 (enExample)
AU (1) AU2003256839B2 (enExample)
CA (1) CA2492295C (enExample)
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Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7635477B2 (en) 2002-07-25 2009-12-22 The General Hospital Corporation Parathyroid hormone receptor activation and stem and progenitor cell expansion
AU2003256839B2 (en) 2002-07-25 2009-10-29 The General Hospital Corporation Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion
AU2005304687B2 (en) * 2004-11-11 2012-01-19 The General Hosptial Corporation Parathyroid hormone receptor activation and stem and progenitor cell expansion
WO2008073748A1 (en) 2006-12-08 2008-06-19 University Of Rochester Expansion of hematopoietic stem cells
ES2583002T3 (es) * 2007-04-09 2016-09-16 The Board Of Trustees Of The University Of Arkansas Proteínas de fusión de un dominio de enlazamiento a colágeno y hormona paratiroidea
WO2011011675A1 (en) * 2009-07-23 2011-01-27 Zelos Therapeutics, Inc. Pharmaceutically acceptable formulations/compositions for peptidyl drugs
ES2816009T3 (es) 2011-12-14 2021-03-31 Univ Arkansas Administración de agentes terapéuticos mediante una proteína de unión a colágeno
US9526765B2 (en) 2012-02-09 2016-12-27 The Kitasato Institute Delivery of therapeutic agents by a collagen binding protein
US20190177687A1 (en) * 2016-06-23 2019-06-13 Tithon Biotech Inc. Cells expressing parathyroid hormone 1 receptor and uses thereof
JP7397440B2 (ja) 2017-02-10 2023-12-13 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー コラーゲン結合薬剤組成物およびその使用方法
US12403179B2 (en) 2021-02-18 2025-09-02 The Board Of Trustees Of The University Of Arkansas Release of growth factors at wound healing stages

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09301887A (ja) * 1996-02-01 1997-11-25 Chugai Pharmaceut Co Ltd 血小板減少症の予防剤および治療剤
WO2000070022A2 (en) * 1999-05-14 2000-11-23 City Of Hope Ex vivo expansion of mammalian hematopoietic stem cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5747456A (en) * 1994-12-19 1998-05-05 Beth Israel Deaconess Medical Center Continuous low-dose administration of parathyroid hormone or its agonist
EP0878201B1 (en) * 1996-02-01 2002-06-19 Chugai Seiyaku Kabushiki Kaisha Medicaments for the treatment or prevention of thrombocytopenia
AU6766100A (en) 1999-08-13 2001-03-13 University Of Rochester Ex vivo generation of functional osteoclasts from bone marrow in a three-dimensional bioreactor
US6316410B1 (en) * 1999-09-22 2001-11-13 National Research Council Of Canada Parathyroid hormone analogues for the treatment of osteoporosis
AU2003256839B2 (en) 2002-07-25 2009-10-29 The General Hospital Corporation Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09301887A (ja) * 1996-02-01 1997-11-25 Chugai Pharmaceut Co Ltd 血小板減少症の予防剤および治療剤
WO2000070022A2 (en) * 1999-05-14 2000-11-23 City Of Hope Ex vivo expansion of mammalian hematopoietic stem cells

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US20060257376A1 (en) 2006-11-16
US7776334B2 (en) 2010-08-17
US7429383B2 (en) 2008-09-30
WO2004011484A3 (en) 2004-11-04
AU2003256839A1 (en) 2004-02-16
EP1545603A4 (en) 2006-08-23
WO2004011484A2 (en) 2004-02-05
EP1545603B1 (en) 2015-09-16
AU2003256839B2 (en) 2009-10-29
CA2492295A1 (en) 2004-02-05
US20090092625A1 (en) 2009-04-09
WO2004011484A9 (en) 2004-06-10
CA2492295C (en) 2014-01-28
JP2006512897A (ja) 2006-04-20
EP1545603A2 (en) 2005-06-29

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