JP4711398B2 - ナノ構造表面を有する動的に制御可能な生物学的／化学的検出器 - Google Patents

ナノ構造表面を有する動的に制御可能な生物学的／化学的検出器 Download PDF

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JP4711398B2
JP4711398B2 JP2005083221A JP2005083221A JP4711398B2 JP 4711398 B2 JP4711398 B2 JP 4711398B2 JP 2005083221 A JP2005083221 A JP 2005083221A JP 2005083221 A JP2005083221 A JP 2005083221A JP 4711398 B2 JP4711398 B2 JP 4711398B2
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particles
nanostructure
droplet
detector
reagent
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JP2005274573A (ja
JP2005274573A5 (enExample
Inventor
アーニー スサンヌ
ニキータ クロウペンキン トーマス
マイケル ライアンズ アラン
ルイーズ マンディッチ メアリー
ジェー．シャベル マイケル
アシュレイ テイラー ジョセフ
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アルカテル−ルーセント ユーエスエー インコーポレーテッド
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5088—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0436—Moving fluids with specific forces or mechanical means specific forces vibrational forces acoustic forces, e.g. surface acoustic waves [SAW]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2005083221A 2004-03-23 2005-03-23 ナノ構造表面を有する動的に制御可能な生物学的／化学的検出器 Expired - Fee Related JP4711398B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/806,543 US7048889B2 (en) 2004-03-23 2004-03-23 Dynamically controllable biological/chemical detectors having nanostructured surfaces
US10/806543 2004-03-23

Publications (3)

Publication Number Publication Date
JP2005274573A JP2005274573A (ja) 2005-10-06
JP2005274573A5 JP2005274573A5 (enExample) 2008-05-08
JP4711398B2 true JP4711398B2 (ja) 2011-06-29

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JP2005083221A Expired - Fee Related JP4711398B2 (ja) 2004-03-23 2005-03-23 ナノ構造表面を有する動的に制御可能な生物学的／化学的検出器

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Country Link
US (1) US7048889B2 (enExample)
EP (1) EP1584375B1 (enExample)
JP (1) JP4711398B2 (enExample)
DE (1) DE602005007789D1 (enExample)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040191127A1 (en) 2003-03-31 2004-09-30 Avinoam Kornblit Method and apparatus for controlling the movement of a liquid on a nanostructured or microstructured surface
US8124423B2 (en) 2003-09-30 2012-02-28 Alcatel Lucent Method and apparatus for controlling the flow resistance of a fluid on nanostructured or microstructured surfaces
US7785733B2 (en) * 2003-11-18 2010-08-31 Alcatel-Lucent Usa Inc. Reserve cell-array nanostructured battery
US7749646B2 (en) * 2004-03-18 2010-07-06 Alcatel-Lucent Usa Inc. Reversibly-activated nanostructured battery
US7323033B2 (en) * 2004-04-30 2008-01-29 Lucent Technologies Inc. Nanostructured surfaces having variable permeability
US7608446B2 (en) * 2004-09-30 2009-10-27 Alcatel-Lucent Usa Inc. Nanostructured surface for microparticle analysis and manipulation
PL1859330T3 (pl) 2005-01-28 2013-01-31 Univ Duke Urządzenia i sposoby manipulacji kropelkami na płytkach obwodów drukowanych
US8734003B2 (en) 2005-09-15 2014-05-27 Alcatel Lucent Micro-chemical mixing
US8721161B2 (en) 2005-09-15 2014-05-13 Alcatel Lucent Fluid oscillations on structured surfaces
US20070207272A1 (en) * 2006-03-03 2007-09-06 Puri Ishwar K Method and apparatus for magnetic mixing in micron size droplets
US9476856B2 (en) 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US20070259156A1 (en) * 2006-05-03 2007-11-08 Lucent Technologies, Inc. Hydrophobic surfaces and fabrication process
US9675972B2 (en) 2006-05-09 2017-06-13 Advanced Liquid Logic, Inc. Method of concentrating beads in a droplet
US7449649B2 (en) * 2006-05-23 2008-11-11 Lucent Technologies Inc. Liquid switch
US8128798B2 (en) 2006-07-10 2012-03-06 Hitachi High-Technologies Corporation Liquid transfer device
US8047235B2 (en) * 2006-11-30 2011-11-01 Alcatel Lucent Fluid-permeable body having a superhydrophobic surface
US20080169003A1 (en) * 2007-01-17 2008-07-17 Nasa Headquarters Field reactive amplification controlling total adhesion loading
US20080186801A1 (en) * 2007-02-06 2008-08-07 Qisda Corporation Bubble micro-pump and two-way fluid-driving device, particle-sorting device, fluid-mixing device, ring-shaped fluid-mixing device and compound-type fluid-mixing device using the same
EP2111554B1 (en) 2007-02-09 2013-05-08 Advanced Liquid Logic, Inc. Droplet actuator devices and methods employing magnetic beads
US8345253B2 (en) * 2007-02-21 2013-01-01 The Royal Institution for the Advancement of Learning/McGill University and Her Majesty the Queen in Right of Canada System and method for surface plasmon resonance based detection of molecules
DE102007019842A1 (de) * 2007-04-25 2008-10-30 Forschungsinstitut Für Die Biologie Landwirtschaftlicher Nutztiere Verfahren und Anordnung zum elektrischen Kontaktieren eines membranumhüllten Objekts mit einer Elektrode
US8702938B2 (en) 2007-09-04 2014-04-22 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
EP2237955A4 (en) 2007-12-23 2016-04-20 Advanced Liquid Logic Inc DROPLET FORMATION ACTUATOR CONFIGURATIONS, AND METHODS OF PERFORMING DROPLET FORMING OPERATIONS
US7832462B2 (en) * 2008-03-31 2010-11-16 Alcatel-Lucent Usa Inc. Thermal energy transfer device
US8025271B2 (en) * 2008-03-31 2011-09-27 Alcatel Lucent Directed-flow conduit
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
US11786036B2 (en) 2008-06-27 2023-10-17 Ssw Advanced Technologies, Llc Spill containing refrigerator shelf assembly
US8286561B2 (en) 2008-06-27 2012-10-16 Ssw Holding Company, Inc. Spill containing refrigerator shelf assembly
WO2010042668A1 (en) 2008-10-07 2010-04-15 Ross Technology Corporation Spill resistant surfaces having hydrophobic and oleophobic borders
US8110796B2 (en) 2009-01-17 2012-02-07 The George Washington University Nanophotonic production, modulation and switching of ions by silicon microcolumn arrays
US9490113B2 (en) * 2009-04-07 2016-11-08 The George Washington University Tailored nanopost arrays (NAPA) for laser desorption ionization in mass spectrometry
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
ES2613885T3 (es) 2009-11-04 2017-05-26 Ssw Holding Company, Inc. Superficies de aparatos de cocción que tienen un patrón de confinamiento de salpicaduras y procedimientos de fabricación de las mismas
WO2011057197A2 (en) 2009-11-06 2011-05-12 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel electrophoresis and molecular analysis
EP2516669B1 (en) 2009-12-21 2016-10-12 Advanced Liquid Logic, Inc. Enzyme assays on a droplet actuator
MX2012010669A (es) 2010-03-15 2013-02-07 Ross Technology Corp Destacadores y metodos para producir supreficies hidrofobas.
KR101229044B1 (ko) 2010-10-21 2013-02-04 주식회사 넥스비보 미소입자 처리 장치
DE102011115622A1 (de) 2010-12-20 2012-06-21 Technische Universität Ilmenau Mikropumpe sowie Vorrichtung und Verfahren zur Erzeugung einer Fluidströmung
US9486802B2 (en) 2011-01-21 2016-11-08 Fluimedix Aps Method of controlling a flow
MX2013009609A (es) 2011-02-21 2013-09-16 Ross Technology Corp Revestimiento suoerhidrofobos y oleofobos con sistemas aglutinantes con bajo contenido de compuestos organicos volatiles.
CA2833897C (en) 2011-05-09 2020-05-19 Advanced Liquid Logic, Inc. Microfluidic feedback using impedance detection
EP2729792A4 (en) 2011-07-06 2015-03-18 Advanced Liquid Logic Inc STORING REAGENTS ON A DROPLET HANDLING ACTUATOR
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays
US9446404B2 (en) 2011-07-25 2016-09-20 Advanced Liquid Logic, Inc. Droplet actuator apparatus and system
DE102011085428A1 (de) 2011-10-28 2013-05-02 Schott Ag Einlegeboden
WO2013078216A1 (en) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Glucose-6-phosphate dehydrogenase assays
EP2791255B1 (en) 2011-12-15 2017-11-01 Ross Technology Corporation Composition and coating for superhydrophobic performance
DK2839295T3 (en) * 2012-04-20 2017-05-15 Hewlett-Packard Dev Company Integrated sensors
CN104520392A (zh) 2012-06-25 2015-04-15 罗斯科技公司 具有疏水和/或疏油性质的弹性体涂层
CN104603595B (zh) 2012-06-27 2017-08-08 先进流体逻辑公司 用于减少气泡形成的技术和液滴致动器设计
WO2014010534A1 (ja) 2012-07-13 2014-01-16 東洋製罐株式会社 内容物に対する滑り性に優れた包装容器
EP2910604B1 (en) * 2012-10-16 2022-04-13 Daikin Industries, Ltd. High dielectric film
DE102012112494A1 (de) * 2012-12-18 2014-07-03 Karlsruher Institut für Technologie Verfahren zum Übertragen einer Transferflüssigkeit von einer Vorlagefläche in eine Mehrzahl von diskreten Kompartimenten auf einer Zielfläche und Transferfläche zur Durchführung des Verfahrens
US10161037B2 (en) * 2013-03-20 2018-12-25 Massachusetts Institute Of Technology Condensation on surfaces
US9182589B2 (en) 2014-02-25 2015-11-10 Amazon Technologies, Inc. Electrowetting display structures
JP6579466B2 (ja) * 2015-04-06 2019-09-25 国立大学法人大阪大学 サンプル検出デバイス用のサンプル捕集装置、及び該サンプル捕集装置を含むサンプル検出デバイス
EP3287388A4 (en) * 2015-04-24 2018-12-19 Toyo Seikan Co., Ltd. Structure having externally added region on surface
EP3281910B1 (en) * 2016-08-11 2019-10-02 IMEC vzw Method of forming micro-pipes on a substrate and a structure formed therewith
CN107833839B (zh) * 2017-10-12 2020-04-24 东南大学 一种基于纳米棒结构的按插式键合单元

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
CN1192097C (zh) * 1995-03-10 2005-03-09 梅索磅秤技术有限公司 多阵列、多特异性的电化学发光检验
US5674592A (en) * 1995-05-04 1997-10-07 Minnesota Mining And Manufacturing Company Functionalized nanostructured films
US6387707B1 (en) * 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
JP3791999B2 (ja) * 1997-03-24 2006-06-28 株式会社アドバンス 液体微粒子ハンドリング装置
JPH1138336A (ja) * 1997-07-18 1999-02-12 Fujitsu Ltd 光スイッチング素子
US6042959A (en) * 1997-10-10 2000-03-28 3M Innovative Properties Company Membrane electrode assembly and method of its manufacture
US6123819A (en) * 1997-11-12 2000-09-26 Protiveris, Inc. Nanoelectrode arrays
US6287765B1 (en) * 1998-05-20 2001-09-11 Molecular Machines, Inc. Methods for detecting and identifying single molecules
US6185961B1 (en) * 1999-01-27 2001-02-13 The United States Of America As Represented By The Secretary Of The Navy Nanopost arrays and process for making same
JP3778041B2 (ja) * 2000-12-08 2006-05-24 コニカミノルタホールディングス株式会社 粒子分離機構及び粒子分離装置
DE10062246C1 (de) 2000-12-14 2002-05-29 Advalytix Ag Verfahren und Vorrichtung zur Manipulation kleiner Flüssigkeitsmengen
WO2002065515A2 (en) * 2001-02-14 2002-08-22 Science & Technology Corporation @ Unm Nanostructured devices for separation and analysis
KR100455284B1 (ko) * 2001-08-14 2004-11-12 삼성전자주식회사 탄소나노튜브를 이용한 고용량의 바이오분자 검출센서
US6545815B2 (en) * 2001-09-13 2003-04-08 Lucent Technologies Inc. Tunable liquid microlens with lubrication assisted electrowetting
ATE509272T1 (de) * 2001-11-09 2011-05-15 3Dbiosurfaces Technologies Llc Substrate mit hochliegendem oberflächenbereich für mikroarrays sowie verfahren zur herstellung davon
DE10162188A1 (de) 2001-12-17 2003-06-18 Sunyx Surface Nanotechnologies Hydrophobe Oberfläche mit einer Vielzahl von Elektroden
JP2003254969A (ja) * 2002-03-04 2003-09-10 Seiko Epson Corp マイクロアレイ用基板及びマイクロアレイ用基板製造方法並びにマイクロアレイ、マイクロアレイ製造方法及び装置
SE0201738D0 (sv) * 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
FR2841063B1 (fr) * 2002-06-18 2004-09-17 Commissariat Energie Atomique Dispositif de deplacement de petits volumes de liquide le long d'un micro-catenaire par des forces electrostatiques
US20040191127A1 (en) 2003-03-31 2004-09-30 Avinoam Kornblit Method and apparatus for controlling the movement of a liquid on a nanostructured or microstructured surface
US6911276B2 (en) * 2003-04-15 2005-06-28 Entegris, Inc. Fuel cell with ultraphobic surfaces
US6845788B2 (en) * 2003-04-15 2005-01-25 Entegris, Inc. Fluid handling component with ultraphobic surfaces
US20050118494A1 (en) * 2003-12-01 2005-06-02 Choi Sung H. Implantable biofuel cell system based on nanostructures

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Publication number Publication date
US20060040375A1 (en) 2006-02-23
JP2005274573A (ja) 2005-10-06
DE602005007789D1 (de) 2008-08-14
EP1584375A1 (en) 2005-10-12
US7048889B2 (en) 2006-05-23
EP1584375B1 (en) 2008-07-02

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