JP4709145B2 - 肝細胞癌を治療する方法 - Google Patents

肝細胞癌を治療する方法 Download PDF

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Publication number
JP4709145B2
JP4709145B2 JP2006521860A JP2006521860A JP4709145B2 JP 4709145 B2 JP4709145 B2 JP 4709145B2 JP 2006521860 A JP2006521860 A JP 2006521860A JP 2006521860 A JP2006521860 A JP 2006521860A JP 4709145 B2 JP4709145 B2 JP 4709145B2
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Prior art keywords
zvegf3
residues
seq
antibody
cells
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Expired - Fee Related
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JP2006521860A
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Japanese (ja)
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JP2006528663A (ja
JP2006528663A5 (enExample
Inventor
イー． パルマー，トーマス
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ザイモジェネティクス， インコーポレイテッド
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Publication of JP2006528663A5 publication Critical patent/JP2006528663A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006521860A 2003-07-25 2004-07-09 肝細胞癌を治療する方法 Expired - Fee Related JP4709145B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49004703P 2003-07-25 2003-07-25
US60/490,047 2003-07-25
PCT/US2004/021835 WO2005011742A1 (en) 2003-07-25 2004-07-09 Method of treating hepatocellular carcinoma

Publications (3)

Publication Number Publication Date
JP2006528663A JP2006528663A (ja) 2006-12-21
JP2006528663A5 JP2006528663A5 (enExample) 2007-11-08
JP4709145B2 true JP4709145B2 (ja) 2011-06-22

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ID=34115347

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006521860A Expired - Fee Related JP4709145B2 (ja) 2003-07-25 2004-07-09 肝細胞癌を治療する方法

Country Status (9)

Country Link
US (4) US20050191304A1 (enExample)
EP (1) EP1660135B1 (enExample)
JP (1) JP4709145B2 (enExample)
AT (1) ATE432716T1 (enExample)
CA (1) CA2529798C (enExample)
DE (1) DE602004021395D1 (enExample)
DK (1) DK1660135T3 (enExample)
ES (1) ES2326978T3 (enExample)
WO (1) WO2005011742A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6893637B1 (en) * 1999-10-21 2005-05-17 Zymogenetics, Inc. Method of treating fibrosis
US9884910B2 (en) * 2012-04-24 2018-02-06 Thrombogenics Nv Anti-PDGF-C antibodies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432673B1 (en) * 1998-12-07 2002-08-13 Zymogenetics, Inc. Growth factor homolog ZVEGF3
DK1137773T3 (da) * 1998-12-07 2008-12-08 Zymogenetics Inc Væsktfaktorhomolog ZVEGF3
US6893637B1 (en) * 1999-10-21 2005-05-17 Zymogenetics, Inc. Method of treating fibrosis

Also Published As

Publication number Publication date
JP2006528663A (ja) 2006-12-21
DK1660135T3 (da) 2009-09-07
US20090028865A1 (en) 2009-01-29
WO2005011742A1 (en) 2005-02-10
US20050191304A1 (en) 2005-09-01
US20110052588A1 (en) 2011-03-03
DE602004021395D1 (de) 2009-07-16
CA2529798C (en) 2014-09-16
CA2529798A1 (en) 2005-02-10
US20070054858A1 (en) 2007-03-08
ATE432716T1 (de) 2009-06-15
EP1660135A1 (en) 2006-05-31
EP1660135B1 (en) 2009-06-03
ES2326978T3 (es) 2009-10-22

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