JP4708661B2 - 増強された3’転写終結構造を含む、レトロウイルスベクター - Google Patents

増強された3’転写終結構造を含む、レトロウイルスベクター Download PDF

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JP4708661B2
JP4708661B2 JP2001582562A JP2001582562A JP4708661B2 JP 4708661 B2 JP4708661 B2 JP 4708661B2 JP 2001582562 A JP2001582562 A JP 2001582562A JP 2001582562 A JP2001582562 A JP 2001582562A JP 4708661 B2 JP4708661 B2 JP 4708661B2
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retroviral vector
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cell
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JP2003532426A5 (enExample
JP2003532426A (ja
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ポーラ・マリー・キャノン
マリア・バルコワ
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ユニバーシティ オブ サザン カリフォルニア
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16041Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/15Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/30Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/36Vector systems having a special element relevant for transcription being a transcription termination element
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/60Vector systems having a special element relevant for transcription from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/20Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
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  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2001582562A 2000-05-12 2001-05-14 増強された3’転写終結構造を含む、レトロウイルスベクター Expired - Fee Related JP4708661B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20388400P 2000-05-12 2000-05-12
US60/203,884 2000-05-12
PCT/IB2001/000826 WO2001085974A2 (en) 2000-05-12 2001-05-14 Retroviral vectors comprising an enhanced 3' transcription termination structure

Publications (3)

Publication Number Publication Date
JP2003532426A JP2003532426A (ja) 2003-11-05
JP2003532426A5 JP2003532426A5 (enExample) 2008-07-03
JP4708661B2 true JP4708661B2 (ja) 2011-06-22

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JP2001582562A Expired - Fee Related JP4708661B2 (ja) 2000-05-12 2001-05-14 増強された3’転写終結構造を含む、レトロウイルスベクター

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US (1) US6620595B2 (enExample)
EP (1) EP1283895A2 (enExample)
JP (1) JP4708661B2 (enExample)
AU (1) AU2001258668A1 (enExample)
CA (1) CA2408786C (enExample)
IL (2) IL152527A0 (enExample)
NZ (1) NZ522264A (enExample)
WO (1) WO2001085974A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE527347T1 (de) 2001-08-02 2011-10-15 Inst Clayton De La Rech Verfahren und zusammensetzungen im zusammenhang mit verbesserten lentivirusvektor- produktionssystemen
NZ554035A (en) * 2004-09-29 2009-11-27 Pioneer Hi Bred Int Corn event DAS-59122-7 and methods for detection thereof
WO2012018607A2 (en) * 2010-07-26 2012-02-09 Adv Biologics, Inc. Vectors and methods for recombinant protein expression
CN102533863A (zh) * 2011-11-25 2012-07-04 上海市儿童医院 一种低通读率慢病毒载体及方法
CN102443604B (zh) * 2011-11-25 2014-12-31 上海市儿童医院 一种安全性慢病毒载体及其应用
JP6586075B2 (ja) 2013-03-14 2019-10-02 トランスレイト バイオ, インコーポレイテッド メッセンジャーrnaの精製方法
GB202114532D0 (en) 2021-10-12 2021-11-24 Oxford Biomedica Ltd Lentiviral Vectors

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Publication number Publication date
US20020042136A1 (en) 2002-04-11
WO2001085974A2 (en) 2001-11-15
WO2001085974A3 (en) 2002-07-04
IL152527A (en) 2009-06-15
EP1283895A2 (en) 2003-02-19
NZ522264A (en) 2004-08-27
US6620595B2 (en) 2003-09-16
IL152527A0 (en) 2003-05-29
CA2408786A1 (en) 2001-11-15
AU2001258668A1 (en) 2001-11-20
CA2408786C (en) 2012-05-29
JP2003532426A (ja) 2003-11-05

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