JP4629673B2 - 電気的に効果的な神経興奮性刺激 - Google Patents
電気的に効果的な神経興奮性刺激 Download PDFInfo
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- JP4629673B2 JP4629673B2 JP2006523283A JP2006523283A JP4629673B2 JP 4629673 B2 JP4629673 B2 JP 4629673B2 JP 2006523283 A JP2006523283 A JP 2006523283A JP 2006523283 A JP2006523283 A JP 2006523283A JP 4629673 B2 JP4629673 B2 JP 4629673B2
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- Prior art keywords
- pulse
- pulses
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- tissue
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3627—Heart stimulators for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
- A61N1/36564—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Electrotherapy Devices (AREA)
Description
医療デバイスは、心筋組織に対して、組織が不応である期間中に1つ又は複数の神経興奮性刺激パルスを送出する。一部の実施形態では、医療デバイスは、組織の脱分極後の約40〜80ミリ秒の期間中にパルスを送出する。例示的な実施形態では、医療デバイスは、埋め込み可能医療デバイスの形態をとる。
は、内因性左心室脱分極を検出するために使用される。
Claims (3)
- 医療デバイスであって、
患者内に埋め込み可能な電極と、
前記患者の心筋組織に対して刺激パルスを送出するパルス発生器であって、前記パルスの幅は、2分の1ミリ秒以下であり、前記パルスの電流振幅は、20ミリアンペア以下である、パルス発生器と、
前記組織が不応である期間中に前記刺激パルスを送出するように前記パルス発生器を制御するプロセッサと、
を備える、医療デバイス。 - プログラム可能プロセッサが、患者の心筋組織に対する、該組織が不応である期間中における刺激パルスの送出を制御するようにさせる命令を含むコンピュータ読み取り可能媒体であって、前記パルスの幅は、2分の1ミリ秒以下であり、前記パルスの電流振幅は、20ミリアンペア以下である、コンピュータ読み取り可能媒体。
- 医療デバイスであって、
患者の心筋組織に対して刺激パルスを送出する手段であって、前記パルスの幅は、2分の1ミリ秒以下であり、前記パルスの電流振幅は、20ミリアンペア以下である、刺激パルスを送出する手段と、
前記組織が不応である期間中に前記刺激パルスを送出するように前記送出手段を制御する手段と、
を備える、医療デバイス。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/638,855 US7292888B2 (en) | 2003-08-11 | 2003-08-11 | Cardiac stimulation during a refractory period |
PCT/US2004/025776 WO2005016449A1 (en) | 2003-08-11 | 2004-08-10 | Electrically efficient neurally-excitable stimulation |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007502160A JP2007502160A (ja) | 2007-02-08 |
JP4629673B2 true JP4629673B2 (ja) | 2011-02-09 |
Family
ID=34135751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006523283A Expired - Fee Related JP4629673B2 (ja) | 2003-08-11 | 2004-08-10 | 電気的に効果的な神経興奮性刺激 |
Country Status (7)
Country | Link |
---|---|
US (1) | US7292888B2 (ja) |
EP (1) | EP1663388B1 (ja) |
JP (1) | JP4629673B2 (ja) |
CA (1) | CA2535553A1 (ja) |
DE (1) | DE602004026607D1 (ja) |
IL (1) | IL173671A0 (ja) |
WO (1) | WO2005016449A1 (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7233824B2 (en) * | 2003-10-07 | 2007-06-19 | Medtronic, Inc. | Secure and efficacious therapy delivery for an extra-systolic stimulation pacing engine |
US7734348B2 (en) * | 2005-05-10 | 2010-06-08 | Cardiac Pacemakers, Inc. | System with left/right pulmonary artery electrodes |
US7765000B2 (en) * | 2005-05-10 | 2010-07-27 | Cardiac Pacemakers, Inc. | Neural stimulation system with pulmonary artery lead |
WO2007019491A2 (en) * | 2005-08-08 | 2007-02-15 | Katims Jefferson J | Method and apparatus for producing therapeutic and diagnostic stimulation |
US8046064B2 (en) * | 2006-04-24 | 2011-10-25 | Medtronic, Inc. | Method of delivering PESP/ICC as well as adjusting the refractory period of the heart |
US8478406B2 (en) * | 2006-04-24 | 2013-07-02 | Medtronic, Inc. | Apparatus and methods of delivering an enhanced refractory period stimulation therapy |
US7835789B2 (en) * | 2006-04-24 | 2010-11-16 | Medtronic, Inc. | Refractory period stimulation to increase ventricular performance |
US7761151B2 (en) | 2006-08-23 | 2010-07-20 | Cardiac Pacemakers, Inc. | Intermittent high-energy cardiac stimulation for therapeutic effect |
US20080188900A1 (en) * | 2006-12-21 | 2008-08-07 | G&L Consulting, Llc | Heart rate reduction method and system |
US8103343B2 (en) | 2007-05-03 | 2012-01-24 | Cardiac Pacemakers, Inc. | Automatic modulation of pacing timing intervals using beat to beat measures |
US7957802B2 (en) * | 2007-08-20 | 2011-06-07 | Cardiac Pacemakers, Inc. | Method, apparatus, and system to optimize cardiac preload based on measured pulmonary artery pressure |
US7904156B2 (en) * | 2007-08-20 | 2011-03-08 | Cardiac Pacemakers, Inc. | Modulation of AV delay to control ventricular interval variability |
EP2231265A2 (en) | 2007-12-12 | 2010-09-29 | Cardiac Pacemakers, Inc. | System for delivering neurostimulation from pulmonary artery |
WO2010030700A1 (en) * | 2008-09-09 | 2010-03-18 | Incube Labs, Llc | Energy harvesting mechanism |
US8634910B2 (en) * | 2008-09-16 | 2014-01-21 | Cardiac Pacemakers, Inc. | Cardiac function management integrating cardiac contractility modulation |
US9026212B2 (en) * | 2008-09-23 | 2015-05-05 | Incube Labs, Llc | Energy harvesting mechanism for medical devices |
WO2017087681A1 (en) | 2015-11-17 | 2017-05-26 | Inspire Medical Systems, Inc. | Microstimulation sleep disordered breathing (sdb) therapy device |
Family Cites Families (32)
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US10492A (en) * | 1854-02-07 | Improvement in machines for ruling paper | ||
US31994A (en) * | 1861-04-09 | Roller-skate | ||
US28221A (en) * | 1860-05-08 | Improvement in hose-couplings | ||
US4554922A (en) * | 1982-09-30 | 1985-11-26 | Prystowsky Eric N | Method of inhibiting cardiac arrhythmias |
US5213098A (en) * | 1991-07-26 | 1993-05-25 | Medtronic, Inc. | Post-extrasystolic potentiation stimulation with physiologic sensor feedback |
US5224476A (en) * | 1992-02-24 | 1993-07-06 | Duke University | Method and apparatus for controlling fibrillation or tachycardia |
DE69307510T2 (de) * | 1992-06-30 | 1997-07-31 | Medtronic Inc | Vorrichtung zur behandlung von angina pectoris |
EP0647149B1 (en) * | 1992-06-30 | 1997-01-15 | Medtronic, Inc. | Apparatus for treatment of heart disorders |
US5411531A (en) * | 1993-09-23 | 1995-05-02 | Medtronic, Inc. | Method and apparatus for control of A-V interval |
US5564434A (en) * | 1995-02-27 | 1996-10-15 | Medtronic, Inc. | Implantable capacitive absolute pressure and temperature sensor |
IL125424A0 (en) * | 1998-07-20 | 1999-03-12 | New Technologies Sa Ysy Ltd | Pacing with hemodynamic enhancement |
ATE290905T1 (de) * | 1996-01-08 | 2005-04-15 | Impulse Dynamics Nv | Vorrichtung zur steuerung der herzaktivität unter verwendung von nicht-erregender vorstimulation |
IL119261A0 (en) * | 1996-09-17 | 1996-12-05 | New Technologies Sa Ysy Ltd | Electrical muscle controller |
WO1998010830A1 (en) | 1996-09-16 | 1998-03-19 | Impulse Dynamics (Israel) Ltd. | Fencing of cardiac muscles |
US5755761A (en) * | 1996-04-26 | 1998-05-26 | Pharmatarget, Inc. | Atrial pacing catheter and method having multiple electrodes in the right atrium and coronary sinus |
US5800464A (en) * | 1996-10-03 | 1998-09-01 | Medtronic, Inc. | System for providing hyperpolarization of cardiac to enhance cardiac function |
US5873896A (en) * | 1997-05-27 | 1999-02-23 | Uab Research Foundation | Cardiac device for reducing arrhythmia |
US5978704A (en) * | 1997-06-03 | 1999-11-02 | Uab Research Foundation | Method and apparatus for treating cardiac arrhythmia |
US6243603B1 (en) * | 1998-09-15 | 2001-06-05 | Uab Research Foundation | Methods and apparatus for detecting medical conditions of the heart |
AU1072300A (en) * | 1998-11-06 | 2000-05-29 | Impulse Dynamics N.V. | Regulation of excitable tissue control of the heart based on physiological input |
US6205357B1 (en) * | 1998-12-04 | 2001-03-20 | Uab Research Foundation | Methods and apparatus for detecting and treating medical conditions of the heart |
US6128528A (en) * | 1999-03-18 | 2000-10-03 | Medtronics, Inc. | Error code calculations for data stored in an implantable medical device |
US6263242B1 (en) | 1999-03-25 | 2001-07-17 | Impulse Dynamics N.V. | Apparatus and method for timing the delivery of non-excitatory ETC signals to a heart |
US6370430B1 (en) * | 1999-03-25 | 2002-04-09 | Impulse Dynamics N.V. | Apparatus and method for controlling the delivery of non-excitatory cardiac contractility modulating signals to a heart |
US6115628A (en) * | 1999-03-29 | 2000-09-05 | Medtronic, Inc. | Method and apparatus for filtering electrocardiogram (ECG) signals to remove bad cycle information and for use of physiologic signals determined from said filtered ECG signals |
US6263241B1 (en) * | 1999-04-30 | 2001-07-17 | Intermedics, Inc. | Method and apparatus for treatment of cardiac electromechanical dissociation |
US6223072B1 (en) * | 1999-06-08 | 2001-04-24 | Impulse Dynamics N.V. | Apparatus and method for collecting data useful for determining the parameters of an alert window for timing delivery of ETC signals to a heart under varying cardiac conditions |
US6256535B1 (en) * | 1999-06-29 | 2001-07-03 | Pacesetter, Inc. | Method for delivering cardiac therapy and a cardiac therapy device for implementing the same |
US6560489B2 (en) * | 1999-08-24 | 2003-05-06 | Em Vascular, Inc. | Therapeutic device and method for treating diseases of cardiac muscle |
US6810286B2 (en) | 2000-03-06 | 2004-10-26 | Medtronic, Inc | Stimulation for delivery of molecular therapy |
US6438408B1 (en) * | 2000-12-28 | 2002-08-20 | Medtronic, Inc. | Implantable medical device for monitoring congestive heart failure |
US7191000B2 (en) | 2001-07-31 | 2007-03-13 | Cardiac Pacemakers, Inc. | Cardiac rhythm management system for edema |
-
2003
- 2003-08-11 US US10/638,855 patent/US7292888B2/en not_active Expired - Fee Related
-
2004
- 2004-08-10 DE DE602004026607T patent/DE602004026607D1/de active Active
- 2004-08-10 JP JP2006523283A patent/JP4629673B2/ja not_active Expired - Fee Related
- 2004-08-10 EP EP04780585A patent/EP1663388B1/en not_active Not-in-force
- 2004-08-10 CA CA002535553A patent/CA2535553A1/en not_active Abandoned
- 2004-08-10 WO PCT/US2004/025776 patent/WO2005016449A1/en active Application Filing
-
2006
- 2006-02-12 IL IL173671A patent/IL173671A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE602004026607D1 (de) | 2010-05-27 |
US7292888B2 (en) | 2007-11-06 |
JP2007502160A (ja) | 2007-02-08 |
CA2535553A1 (en) | 2005-02-24 |
WO2005016449A1 (en) | 2005-02-24 |
US20050038479A1 (en) | 2005-02-17 |
IL173671A0 (en) | 2006-07-05 |
EP1663388B1 (en) | 2010-04-14 |
EP1663388A1 (en) | 2006-06-07 |
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