JP4611286B2 - 磁気共鳴映像法で利用するための温度調節器内蔵型医療用装置 - Google Patents
磁気共鳴映像法で利用するための温度調節器内蔵型医療用装置 Download PDFInfo
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Description
本願で開示した他の実施態様によれば、医療用装置を画像化する方法が提供される。 この医療用装置は、ハウジング、このハウジングに対して作動可能に関与する導体からなり、かつ医療用装置の長手軸方向に配置されるバンド、それに、体温より高いキュリー点を有し、かつハウジングに対して作動可能に関与する物質を具備している。 この方法によれば、まず、被験者に医療用装置が挿入される。 次に、MRI画像に関する十分な(コントラスト)効果を引き出すために、高周波パルスを発生させて、医療用装置の少なくとも一部を体温より高い温度にまで加熱する。 その後、高周波パルスの発生を止め、そして、磁気共鳴映像法を用いて医療用装置を視覚化する。
5……液体
6、150、219、417、420……ハウジング
9……温度調節器(第一温度調節器)
10……温度調節器(第二温度調節器)
12、438……親水性層
15、193……物質(第一の物質)
16……物質(第二の物質)
18……温熱帯
21……放射線不透過性物質
24、165、264……表面
25……外部表面
26……内部表面
27……磁気共鳴映像装置
30、222、480……内腔
57……第一工程
60、66、69……調節工程
63、558……視覚化工程
72……反復工程
153、154……バンド
156……導体
159、162、183……端
171……長さ
174、252、435……長手軸
177……マーカー
180……幅
189……電源
225、226、227……加熱領域
234、483……第一層
237、453……第二層
240、486……第三層
243……第四層
246……第一導電性リング
249……第二導電性リング
255……電気回路形成手段
258……近位末端
261……末端
372……挿入工程
375……発生工程
426……連結手段
423、424……ペルティエ素子
429、430……低温領域
432、433……高温領域
444……N-型半導体セグメント
447……P-型半導体セグメント
450……外周
465……第一導電性ポリマー
468……第二導電性ポリマー
491……導電性ポリマー
549……第一工程
552……通電工程
Claims (28)
- 組織内に挿入されて、磁気共鳴映像装置を用いて設置される医療用装置であって、
ハウジングと、
当該ハウジングに対して作動可能に関与し、かつ当該医療用装置の磁気共鳴映像に変化を及ぼす温度調節器と、
前記ハウジングの外部表面に配置された親水性層と、を備え、
前記親水性層は、ヒドロゲルと、第1のキュリー点を有する物質と、第2のキュリー点を有する物質とを有し、各々の物質は、固有のキュリー点を有する、
ことを特徴とする医療用装置。 - 放射線不透過性物質をさらに含む請求項1に記載の医療用装置。
- 前記キュリー点が、25〜50℃の範囲内にある請求項1に記載の医療用装置。
- 前記キュリー点が、32〜42℃の範囲内にある請求項1に記載の医療用装置。
- 前記キュリー点と体温との差異が、5℃以内である請求項1に記載の医療用装置。
- キュリー点を有する前記物質が、所望のキュリー点を獲得するために、コバルト、パラジウム、ニッケル、珪素、鉄、マンガン、クロムおよび銅からなるグループから選択される少なくとも一つの元素を含む請求項1に記載の医療用装置。
- 前記キュリー点が、体温より高い請求項1に記載の医療用装置。
- 前記キュリー点が、体温より低い請求項1に記載の医療用装置。
- 前記医療用装置の少なくとも一部を冷却するための第一の温度調節器と前記医療用装置の全部または一部を加温するための第二の温度調節器とを具備した請求項1に記載の医療用装置。
- 前記温度調節器が、前記医療用装置の少なくとも一部の温度を変化させることができる請求項1に記載の医療用装置。
- 組織内に挿入されて、磁気共鳴映像装置を用いて設置される医療用装置であって、
ハウジングと、
当該ハウジングに対して作動可能に関与する導体からなり、かつ当該医療用装置の長手軸方向に配置されるバンドと、
バンド相互およびバンドと電源との連絡のための導体であって、かつバンド相互および当該バンドと電源との連絡のための当該導体よりも大きな抵抗値を有するバンドからなる導体と、
前記ハウジングの外部表面に配置された親水性層と、を備え、
前記親水性層は、ヒドロゲルと、第1のキュリー点を有する物質と、第2のキュリー点を有する物質とを有し、各々の物質は、固有のキュリー点を有する、
ことを特徴とする医療用装置。 - バンド相互およびバンドと電源との連絡のための前記導体が、7cmに満たない長さの金属線および環状電気配線を形成するために設置されたマーカーを含む請求項11に記載の医療用装置。
- バンドを含む前記導体とバンド相互およびバンドと電源との連絡のための前記導体との双方が、導電性ポリマーを含む請求項11に記載の医療用装置。
- 前記バンドの幅が、0.8〜10mmである請求項13に記載の医療用装置。
- 前記バンド相互が、3mm〜15mm離間している請求項13に記載の医療用装置。
- 前記ハウジングに対して作動可能に関与する親水性層をさらに含む請求項11に記載の医療用装置。
- 前記医療用装置に対して作動可能に関与し、かつキュリー点を有する物質をさらに含む請求項11に記載の医療用装置。
- 組織内に挿入されて、磁気共鳴映像装置を用いて設置される医療用装置であって、
内腔と、
当該内腔を囲い込む第一層、当該第一層を囲い込む第二層および当該第二層を囲い込む第三層を具備した当該内腔を囲い込むハウジングであって、当該第一層および第三層が、導電性ポリマーを含み、当該第二層が、当該第一層および第三層の導電性ポリマーよりも高い抵抗値を有する導電性ポリマーを各加熱領域に含み、かつ絶縁物質を非加熱領域に含むハウジングと、
当該医療用装置の長手軸方向に設置された少なくとも一つの加熱領域と、
当該医療用装置の末端での当該第一層と当該第三層との間に電気回路を形成するための手段と、
当該第一層上に配置された第一導電性リングと、
外部電源との連絡を可能にするために、当該医療用装置の近位末端での当該第三層上に配置された第二導電性リングと、
前記ハウジングの外部表面に配置された親水性層と、を備え、
前記親水性層は、ヒドロゲルと、第1のキュリー点を有する物質と、第2のキュリー点を有する物質とを有し、各々の物質は、固有のキュリー点を有する、
ことを特徴とする医療用装置。 - 親水性物質を含む第三層を囲い込み、かつ前記ハウジングの表面の少なくとも一部を覆う第四層をさらに含む請求項18に記載の医療用装置。
- 組織内に挿入されて、磁気共鳴映像装置を用いて設置される医療用装置であって、
ハウジングと、
当該ハウジングに対して作動可能に関与し、かつ当該医療用装置の磁気共鳴映像に変化を及ぼす温度調節器と、
その各々が当該ハウジングに対して作動可能に関与する少なくとも一つのペルティエ素子と、
ペルティエ素子相互およびペルティエ素子と電源との連絡のための手段と、
前記ハウジングの外部表面に配置された親水性層と、を備え、
前記親水性層は、ヒドロゲルと、第1のキュリー点を有する物質と、第2のキュリー点を有する物質とを有し、各々の物質は、固有のキュリー点を有する、
ことを特徴とする医療用装置。 - 各ペルティエ素子が、高温領域と低温領域とを具備しており、前記ペルティエ素子が、前記医療用装置の長手軸方向に配置されており、そして、隣接する二つのペルティエ素子の高温領域が、互いに向かい合っている請求項20に記載の医療用装置。
- 各ペルティエ素子が、高温領域と低温領域とを具備しており、前記ペルティエ素子が、前記医療用装置の長手軸方向に配置されており、そして、隣接する二つのペルティエ素子の低温領域が、互いに向かい合っている請求項20に記載の医療用装置。
- ペルティエ素子相互およびペルティエ素子と電源との連絡のための前記手段が、導電性ポリマーを含む請求項20に記載の医療用装置。
- 各ペルティエ素子が、前記医療用装置の外周に互い違いに配列されたN-型およびP-型半導体セグメントからなる請求項20に記載の医療用装置。
- 体温より低いキュリー点を有する物質をさらに含む請求項20に記載の医療用装置。
- 体温より高いキュリー点を有する物質をさらに含む請求項20に記載の医療用装置。
- 組織内に挿入されて、磁気共鳴映像装置を用いて設置される医療用装置であって、
内腔と、
当該内腔を囲い込む第一層、当該第一層を囲い込む第二層および当該第二層を囲い込む第三層を具備した当該内腔を囲い込むハウジングと、
当該医療用装置の長手軸方向に配置された少なくとも一つのペルティエ素子と、を含み、
当該第一層が導電性ポリマーを含み、当該第二層が絶縁層を含み、当該第三層が少なくとも一つのペルティエ素子とペルティエ素子相互およびペルティエ素子と外部電源との連絡のための一片の導電性ポリマーとを含み、
各ペルティエ素子が、比較的に高温の領域と比較的に低温の領域とを具備しており、
ペルティエ素子の高温領域が、隣接するペルティエ素子の低温領域と向かい合わず、かつ各ペルティエ素子が、前記医療用装置の外周に互い違いに配列され、かつ医療用装置の前記第三層内に配置されたN-型およびP-型半導体セグメント、を含み、
前記医療用装置は、前記ハウジングの外部表面に配置された親水性層を備え、
前記親水性層は、ヒドロゲルと、第1のキュリー点を有する物質と、第2のキュリー点を有する物質とを有し、各々の物質は、固有のキュリー点を有する、
ことを特徴とする医療用装置。 - 前記第一層を欠き、前記第三層が少なくとも二片の導電性ポリマーを有しており、各ペルティエ素子が少なくとも三つのN-型半導体セグメントおよび少なくとも三つのP-型半導体セグメントを含み、各ペルティエ素子において第一の導電性ポリマー片が、N-型半導体セグメントの数がP-型半導体セグメントの二倍であるN-型半導体セグメントおよびP-型半導体セグメントに連絡しており、各ペルティエ素子において第二の導電性ポリマー片が、P-型半導体セグメントの数がN-型半導体セグメントの二倍であるN-型半導体セグメントおよびP-型半導体セグメントに連絡しており、当該第一のポリマー片が当該医療用装置の長手軸に沿った方向に電流を流し、および、当該第二のポリマー片が第一のポリマー片と逆方向に電流を流す請求項27に記載の医療用装置。
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2003
- 2003-03-27 US US10/401,227 patent/US8862203B2/en not_active Expired - Fee Related
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2004
- 2004-01-28 ES ES04706087T patent/ES2318267T3/es not_active Expired - Lifetime
- 2004-01-28 WO PCT/US2004/002554 patent/WO2004093959A2/en active Application Filing
- 2004-01-28 JP JP2006508641A patent/JP4611286B2/ja not_active Expired - Fee Related
- 2004-01-28 CA CA002514188A patent/CA2514188A1/en not_active Abandoned
- 2004-01-28 AT AT04706087T patent/ATE414912T1/de not_active IP Right Cessation
- 2004-01-28 EP EP04706087A patent/EP1606640B1/en not_active Expired - Lifetime
- 2004-01-28 DE DE602004017845T patent/DE602004017845D1/de not_active Expired - Lifetime
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ATE414912T1 (de) | 2008-12-15 |
EP1606640A2 (en) | 2005-12-21 |
EP1606640B1 (en) | 2008-11-19 |
CA2514188A1 (en) | 2004-11-04 |
WO2004093959A2 (en) | 2004-11-04 |
US20040193039A1 (en) | 2004-09-30 |
ES2318267T3 (es) | 2009-05-01 |
JP2006521170A (ja) | 2006-09-21 |
DE602004017845D1 (de) | 2009-01-02 |
US8862203B2 (en) | 2014-10-14 |
WO2004093959A3 (en) | 2005-01-20 |
US20150238111A1 (en) | 2015-08-27 |
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