JP4601170B2 - ヒトにおけるのぼせの処置のための方法 - Google Patents

ヒトにおけるのぼせの処置のための方法 Download PDF

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Publication number
JP4601170B2
JP4601170B2 JP2000567204A JP2000567204A JP4601170B2 JP 4601170 B2 JP4601170 B2 JP 4601170B2 JP 2000567204 A JP2000567204 A JP 2000567204A JP 2000567204 A JP2000567204 A JP 2000567204A JP 4601170 B2 JP4601170 B2 JP 4601170B2
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JP
Japan
Prior art keywords
glycopyrrolate
acid
hot flashes
quaternary ammonium
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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JP2000567204A
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English (en)
Japanese (ja)
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JP2002523458A (ja
JP2002523458A5 (enExample
Inventor
アーサー エム． ボブローブ，
ジェフリー ディー． アーマン，
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Individual
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Individual
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Publication date
Priority claimed from US09/184,512 external-priority patent/US5962505A/en
Application filed by Individual filed Critical Individual
Publication of JP2002523458A publication Critical patent/JP2002523458A/ja
Publication of JP2002523458A5 publication Critical patent/JP2002523458A5/ja
Application granted granted Critical
Publication of JP4601170B2 publication Critical patent/JP4601170B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
JP2000567204A 1998-08-31 1999-08-31 ヒトにおけるのぼせの処置のための方法 Expired - Lifetime JP4601170B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US9862998P 1998-08-31 1998-08-31
US60/098,629 1998-08-31
US09/184,512 1998-11-02
US09/184,512 US5962505A (en) 1998-08-31 1998-11-02 Method for treating hot flashes in humans
US09/360,074 US6395757B1 (en) 1998-08-31 1999-07-23 Method for treating hot flashes in humans
US09/360,074 1999-07-23
PCT/US1999/019693 WO2000012087A1 (en) 1998-08-31 1999-08-31 Method for treating hot flashes in humans

Publications (3)

Publication Number Publication Date
JP2002523458A JP2002523458A (ja) 2002-07-30
JP2002523458A5 JP2002523458A5 (enExample) 2006-09-21
JP4601170B2 true JP4601170B2 (ja) 2010-12-22

Family

ID=27378636

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000567204A Expired - Lifetime JP4601170B2 (ja) 1998-08-31 1999-08-31 ヒトにおけるのぼせの処置のための方法

Country Status (7)

Country Link
US (1) US6395757B1 (enExample)
EP (1) EP1123098A4 (enExample)
JP (1) JP4601170B2 (enExample)
CN (1) CN1315860A (enExample)
AU (1) AU762126B2 (enExample)
CA (1) CA2339996C (enExample)
WO (1) WO2000012087A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10136404A1 (de) * 2001-07-26 2003-02-20 Johannes Wohlrab Arzneiformulierung zur topischen Anwendung für die Therapie und Prophylaxe von Hyperhidrosis
US20050288343A1 (en) * 2004-05-19 2005-12-29 Andrew Rusowicz Process of preparing substituted carbamates and intermediates thereof
EP1861361A1 (en) * 2005-03-24 2007-12-05 Sosei R&D Ltd. Glycopyrronium salts and their therapeutic use
US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
US8053004B2 (en) * 2007-10-08 2011-11-08 Starmaker Products, Llc Ointment for topical treatment of hot flashes and method of use
CN104507465A (zh) 2012-06-08 2015-04-08 俄亥俄州立大学 使用生育三烯酚治疗灼伤和瘢痕损伤
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
ES2981043T3 (es) 2013-02-28 2024-10-07 Journey Medical Corp Procedimiento para fabricar tosilato de glicopirrolato treo
WO2015028976A2 (en) * 2013-08-30 2015-03-05 Mahesh Kandula Compounds and methods for the treatment of inflammatory diseases

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2956062A (en) 1959-02-26 1960-10-11 Robins Co Inc A H Esters of amino alcohols
US3943242A (en) 1974-04-10 1976-03-09 American Cyanamid Company Deodorant composition containing a quaternary ammonium saccharinate salt
US4096254A (en) 1976-05-10 1978-06-20 Richardson-Merrell Inc. Method of treating the symptoms of menopause and osteoporosis
US4824676A (en) * 1984-10-11 1989-04-25 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
AU592322B2 (en) * 1984-10-11 1990-01-11 Key Pharmaceuticals, Inc. Physiological means of enhancing transdermal delivery of drugs
US5008111A (en) 1984-10-11 1991-04-16 Schering Corporation Physiological means of enhancing transdermal delivery of drugs
US5155045A (en) 1985-01-25 1992-10-13 Trustees Of The University Of Penn. Use of male essence to alter female endocrine response
US5223528A (en) 1986-03-17 1993-06-29 University Of Florida Anticholinergic compounds, composititons and methods of treatment
US5258388A (en) 1986-03-17 1993-11-02 University Of Florida Anticholinergic compounds, compositions and methods of treatment
US5462950A (en) 1993-12-21 1995-10-31 Eli Lilly And Company Methods of treating menstrual symptoms and compositions therefore
US5512555A (en) 1994-07-21 1996-04-30 Merck & Co., Inc. Method of treating sweat-related conditions using finasteride, epristeride and a cholestan-3-one
US5525347A (en) 1995-01-31 1996-06-11 Medical University Of South Carolina Composition and methods for treating performance anxiety
US5744463A (en) 1996-06-03 1998-04-28 Bair; Glenn O. Treatment of side effects of progestins and progesterone analogues used for birth control
US5962505A (en) * 1998-08-31 1999-10-05 Bobrove; Arthur M. Method for treating hot flashes in humans

Also Published As

Publication number Publication date
EP1123098A1 (en) 2001-08-16
WO2000012087A1 (en) 2000-03-09
AU5903199A (en) 2000-03-21
CN1315860A (zh) 2001-10-03
EP1123098A4 (en) 2002-01-02
JP2002523458A (ja) 2002-07-30
AU762126B2 (en) 2003-06-19
CA2339996A1 (en) 2000-03-09
US6395757B1 (en) 2002-05-28
CA2339996C (en) 2009-06-16

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