JP4588703B2 - 螺旋配列超音波トランスデューサを備えたアブレーション装置 - Google Patents
螺旋配列超音波トランスデューサを備えたアブレーション装置 Download PDFInfo
- Publication number
- JP4588703B2 JP4588703B2 JP2006521172A JP2006521172A JP4588703B2 JP 4588703 B2 JP4588703 B2 JP 4588703B2 JP 2006521172 A JP2006521172 A JP 2006521172A JP 2006521172 A JP2006521172 A JP 2006521172A JP 4588703 B2 JP4588703 B2 JP 4588703B2
- Authority
- JP
- Japan
- Prior art keywords
- ultrasonic transducer
- cylindrical
- transducer
- cylindrical ultrasonic
- ablation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000002679 ablation Methods 0.000 title claims description 128
- 239000000463 material Substances 0.000 claims description 55
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 44
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 27
- 239000002184 metal Substances 0.000 claims description 27
- 229910052751 metal Inorganic materials 0.000 claims description 27
- 229910010293 ceramic material Inorganic materials 0.000 claims description 14
- 229910052737 gold Inorganic materials 0.000 claims description 14
- 239000010931 gold Substances 0.000 claims description 14
- 230000007246 mechanism Effects 0.000 claims description 11
- 229920000642 polymer Polymers 0.000 claims description 10
- 229910052759 nickel Inorganic materials 0.000 claims description 9
- 238000002604 ultrasonography Methods 0.000 claims description 9
- 229920006332 epoxy adhesive Polymers 0.000 claims description 3
- 210000001519 tissue Anatomy 0.000 description 64
- 238000000034 method Methods 0.000 description 62
- 210000003492 pulmonary vein Anatomy 0.000 description 55
- 230000001746 atrial effect Effects 0.000 description 31
- 206010003658 Atrial Fibrillation Diseases 0.000 description 20
- 208000014674 injury Diseases 0.000 description 17
- 230000008733 trauma Effects 0.000 description 17
- 206010003119 arrhythmia Diseases 0.000 description 14
- 239000012530 fluid Substances 0.000 description 13
- 210000005246 left atrium Anatomy 0.000 description 12
- 230000008569 process Effects 0.000 description 12
- 230000002159 abnormal effect Effects 0.000 description 11
- 230000037361 pathway Effects 0.000 description 10
- 238000001356 surgical procedure Methods 0.000 description 10
- 238000000429 assembly Methods 0.000 description 9
- 230000000712 assembly Effects 0.000 description 9
- 238000013461 design Methods 0.000 description 9
- 238000011282 treatment Methods 0.000 description 9
- 206010003130 Arrhythmia supraventricular Diseases 0.000 description 8
- 230000006793 arrhythmia Effects 0.000 description 8
- 230000008859 change Effects 0.000 description 8
- 239000000919 ceramic Substances 0.000 description 7
- 210000002837 heart atrium Anatomy 0.000 description 7
- 210000005003 heart tissue Anatomy 0.000 description 7
- 238000012986 modification Methods 0.000 description 7
- 230000004048 modification Effects 0.000 description 7
- 238000012544 monitoring process Methods 0.000 description 7
- 230000002093 peripheral effect Effects 0.000 description 7
- 230000001536 pro-arrhythmogenic effect Effects 0.000 description 7
- 238000000576 coating method Methods 0.000 description 6
- 238000005530 etching Methods 0.000 description 6
- 230000010363 phase shift Effects 0.000 description 6
- 238000004544 sputter deposition Methods 0.000 description 6
- 240000008042 Zea mays Species 0.000 description 5
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 5
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 5
- 239000011248 coating agent Substances 0.000 description 5
- 239000004020 conductor Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 238000003754 machining Methods 0.000 description 5
- 235000009973 maize Nutrition 0.000 description 5
- 210000003748 coronary sinus Anatomy 0.000 description 4
- 239000013078 crystal Substances 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 238000010329 laser etching Methods 0.000 description 4
- 239000010453 quartz Substances 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 3
- 208000007536 Thrombosis Diseases 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 206010061592 cardiac fibrillation Diseases 0.000 description 3
- 238000013153 catheter ablation Methods 0.000 description 3
- 230000001427 coherent effect Effects 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 230000002526 effect on cardiovascular system Effects 0.000 description 3
- 230000002600 fibrillogenic effect Effects 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 238000005476 soldering Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 241000282465 Canis Species 0.000 description 2
- 208000001435 Thromboembolism Diseases 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 2
- 238000004873 anchoring Methods 0.000 description 2
- 238000013130 cardiovascular surgery Methods 0.000 description 2
- 230000015271 coagulation Effects 0.000 description 2
- 238000005345 coagulation Methods 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000010339 dilation Effects 0.000 description 2
- 230000005684 electric field Effects 0.000 description 2
- 230000007831 electrophysiology Effects 0.000 description 2
- 238000002001 electrophysiology Methods 0.000 description 2
- 230000002357 endometrial effect Effects 0.000 description 2
- -1 for example Polymers 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000002107 myocardial effect Effects 0.000 description 2
- 230000000737 periodic effect Effects 0.000 description 2
- 238000007747 plating Methods 0.000 description 2
- 238000005498 polishing Methods 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- 230000003252 repetitive effect Effects 0.000 description 2
- 230000033764 rhythmic process Effects 0.000 description 2
- 230000011218 segmentation Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 210000000115 thoracic cavity Anatomy 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 230000002861 ventricular Effects 0.000 description 2
- 241000282472 Canis lupus familiaris Species 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 201000009273 Endometriosis Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 241000507649 Kerria japonica Species 0.000 description 1
- 208000011682 Mitral valve disease Diseases 0.000 description 1
- 206010050106 Paroxysmal arrhythmia Diseases 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 208000002847 Surgical Wound Diseases 0.000 description 1
- 201000008803 Wolff-Parkinson-white syndrome Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 229910052786 argon Inorganic materials 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000003126 arrythmogenic effect Effects 0.000 description 1
- 230000003143 atherosclerotic effect Effects 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000004375 bundle of his Anatomy 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 238000005229 chemical vapour deposition Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 238000010292 electrical insulation Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 230000005686 electrostatic field Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 210000005240 left ventricle Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 210000004115 mitral valve Anatomy 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 239000003186 pharmaceutical solution Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000007674 radiofrequency ablation Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 210000001013 sinoatrial node Anatomy 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000004528 spin coating Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 239000013077 target material Substances 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
- B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
- B06B1/06—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
- B06B1/0607—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements
- B06B1/0622—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements on one surface
- B06B1/0633—Cylindrical array
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
- A61B17/2202—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement the ultrasound transducer being inside patient's body at the distal end of the catheter
-
- H—ELECTRICITY
- H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
- H10N—ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
- H10N30/00—Piezoelectric or electrostrictive devices
- H10N30/80—Constructional details
- H10N30/87—Electrodes or interconnections, e.g. leads or terminals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
- A61B2017/00238—Type of minimally invasive operation
- A61B2017/00243—Type of minimally invasive operation cardiac
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B2017/22027—Features of transducers
- A61B2017/22028—Features of transducers arrays, e.g. phased arrays
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Mechanical Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Transducers For Ultrasonic Waves (AREA)
Description
本発明は手術装置に関する。詳細には、本発明は、ずれた位相で動作して音響エネルギービームを長手方向において前方または後方に向けることができる複数の螺旋要素を有する組織アブレーショントランスデューサ(ablation transducer)および装置組立体に関する。
身体の様々な異常な組織、特に、身体の様々な体腔を画定する体腔壁に沿った異常な組織を治療するために多数のエネルギー局所送達装置および方法が開発されてきた。例えば、エネルギー局所送達でアテローム性動脈硬化性血管を治療すなわち再開通させることが主な理由で、様々な装置が開示されてきた。従来のいくつかの装置および方法では、血管などの病変内腔の開存性を維持するべく組織にエネルギーを局所的に送達するためにエネルギー送達組立体と心血管ステント装置を組み合わせている。子宮内膜腔に関連した別の異常な壁組織の症状であって、子宮内膜腔の表面に沿った子宮壁組織の異常な増殖によって特徴付けられる子宮内膜症も、エネルギー局所送達装置および方法によって治療されてきた。血栓症を誘導し、血管などのある種の体腔内の出血を制御するために、カテーテルを利用した熱源を用いる他のいくつかの装置および方法も開示されてきた。上記したタイプのエネルギー局所送達装置および関連方法などの詳細な例が、ハーシェンソン(Hershenson)による米国特許第4,672,962号、イノクチ(Inokuchi)らによる同第4,676,258号、ルイーズ(Ruiz)による同第4,790,311号、ストラル(Strul)らによる同第4,807,620号、エッガース(Eggers)らによる同第4,998,933号、カスプルシーク(Kasprzyk)らによる同第5,035,694号、リー(Lee)による同第5,190,540号、スペアーズ(Spears)らによる同第5,226,430号、リー(Lee)による同第5,292,321号、チン(Chin)による同第5,449,380号、エドワーズ(Edwards)による同第5,505,730号、エドワーズ(Edwards)らによる同第5,558,672号、スターン(Stern)らによる同第5,562,720号、オース(Auth)らによる同第4,449,528号、テイラー(Taylor)らによる同第4,522,205号、フッセイン(Hussein)らによる同第4,662,368号、ベヘル(Behl)による同第5,078,736号、およびカンダーパ(Kandarpa)による同第5,178,618号に開示されている。
異常な心室壁組織に関連した一般的で危険な疾病として持続する心不整脈、特に心房細動は、高齢患者によく見られる。心不整脈の患者では、心組織の異常な領域が、洞律動の患者の正常な伝導組織に関連した同期鼓動周期に従わない。代わりに、心組織の異常な領域は、近接組織に異所性に伝導するため、心房周期が乱れて非同期心リズムになる。このような異常な伝導は、例えば、房室(AV)結節およびヒス束の伝導経路に沿った洞房(SA)結節部位、または心室および心房室の壁部を形成する心筋組織などの心臓の様々な領域で起こることが知られている。
様々な形の心房細動も、心房に関連した心筋組織内の孤立した中心の迅速で反復的な発射によって起こる事実上の焦点であると確認された。このような焦点は、発作性心房細動の引き金となったり、細動を持続させたりするであろう。様々な開示に、焦点心房性不整脈(focal atrial arrhythmia)が、左心房の1または複数の肺静脈、特に上肺静脈に沿った少なくとも1つの組織領域から起こる場合が多いことが示されている。
本発明は、音響エネルギービームを長手方向において前方または後方に向けるために位相がずれて動作可能な複数の螺旋要素を有する組織アブレーショントランスデューサおよび装置組立体に関する。本発明の一実施形態では、円筒内側電極を有する円筒超音波トランスデューサが提供される。円筒圧電材料が、内側電極の上に配置される。円筒外側電極が、円筒圧電材料の上に配置されている。円筒外側電極は、この外側電極を複数の別個の螺旋要素に分割している螺旋溝を有する。
用語の定義
以下の用語は、本明細書において以下の意味を有するものとする。
以下に、医療装置システムのアブレーション装置を説明する。開示する装置は、医師が、システムが提供したフィードバック情報を用いて体腔内の医療装置の先端部の正確な位置を求めることができる位置監視システムを含むことができる。このようなフィードバック情報は、体腔内の医療装置の先端部の位置を示す。以下に示す位置監視システムの装置は、肺静脈が左心房から延びた領域において、その領域内の標的周囲組織領域に対してアブレーション部材を配置することを含む適用例に特に適している。従って、このような装置は、この文脈で説明する。しかしながら、本発明の様々な態様は、他の体腔内に医療器具を配置することを含む適用例にも当業者が容易に適合させることができる。
Λ=V/f および Λ=L×COS(α)
この式において、
Λは、入力信号の波長
Vは、水中での音速(1550m/秒)
fは、トランスデューサ要素を駆動する周波数
Lは、トランスデューサを螺旋トランスデューサセグメントに分割する螺旋溝が完全に1回転したときに横切る直線距離と定義することができるねじ山の増分すなわちピッチ
αは、音響エネルギービームとトランスデューサの長軸との間の角度
(1)円筒超音波トランスデューサにおいて、
円筒内側電極と、
前記内側電極の上に配置された円筒圧電材料と、
前記円筒圧電材料の上に配置された円筒外側電極であって、前記円筒外側電極を複数の別個の螺旋要素に分割する螺旋溝を有する、前記円筒外側電極と、を含む、円筒超音波トランスデューサ。
(2)実施態様(1)に記載の円筒超音波トランスデューサにおいて、
前記内側電極が金属層を含む、円筒超音波トランスデューサ。
(3)実施態様(2)に記載の円筒超音波トランスデューサにおいて、
前記金属層がニッケルを含む、円筒超音波トランスデューサ。
(4)実施態様(2)に記載の円筒超音波トランスデューサにおいて、
前記金属層が金を含む、円筒超音波トランスデューサ。
(5)実施態様(1)に記載の円筒超音波トランスデューサにおいて、
前記円筒圧電材料が、高密度微粒子PZTセラミック材料を含む、円筒超音波トランスデューサ。
前記円筒圧電材料が、10μmの鏡面仕上げに研磨されている、円筒超音波トランスデューサ。
(7)実施態様(1)に記載の円筒超音波トランスデューサにおいて、
前記外側電極が金属層を含む、円筒超音波トランスデューサ。
(8)実施態様(7)に記載の円筒超音波トランスデューサにおいて、
前記金属層がニッケルを含む、円筒超音波トランスデューサ。
(9)実施態様(7)に記載の円筒超音波トランスデューサにおいて、
前記金属層が金を含む、円筒超音波トランスデューサ。
(10)実施態様(1)に記載の円筒超音波トランスデューサにおいて、
前記別個の螺旋要素が相互に絡み合っている、円筒超音波トランスデューサ。
前記螺旋溝が、前記圧電材料を実質的に別個の複数のゾーンにさらに分離している、円筒超音波トランスデューサ。
(12)実施態様(11)に記載の円筒超音波トランスデューサにおいて、
前記ゾーンが、螺旋状であって相互に絡み合っている、円筒超音波トランスデューサ。
(13)実施態様(1)に記載の円筒超音波トランスデューサにおいて、
前記外側電極の上に配置された整合層を更に含む、円筒超音波トランスデューサ。
(14)実施態様(13)に記載の円筒超音波トランスデューサにおいて、
前記整合層が前記溝を満たしている、円筒超音波トランスデューサ。
(15)実施態様(13)に記載の円筒超音波トランスデューサにおいて、
前記整合層が低粘度ポリマーを含む、円筒超音波トランスデューサ。
前記ポリマーがエポキシ接着剤である、円筒超音波トランスデューサ。
(17)円筒超音波トランスデューサにおいて、
円筒内側電極と、
前記内側電極の上に配置された円筒圧電材料と、
前記円筒圧電材料の上に配置された円筒外側電極と、
前記外側電極を貫通して、前記円筒圧電材料の少なくとも一部まで延びた螺旋溝であって、前記トランスデューサを、機能的に別個の複数の螺旋トランスデューサセグメントに分割している、前記螺旋溝と、を含む、円筒超音波トランスデューサ。
(18)アブレーション要素において、
長軸に沿って直線状に配列され、相互に螺旋状に設けられた複数の螺旋トランスデューサを含む、アブレーション要素。
(19)アブレーション要素において、
長軸に沿って直線状に配列され、相互に螺旋状に設けられた機能的に別個の複数の螺旋トランスデューサセグメントに分割された超音波トランスデューサを含む、アブレーション要素。
(20)体腔における組織の領域をアブレーションするためのアブレーションカテーテル組立体において、
基端部分および先端部分を有する細長い送達部材と、
前記細長い送達部材の前記先端部分に結合されたアンカー機構であって、前記体腔における組織の実質的な部分に係合するように構成された、前記アンカー機構と、
前記細長い送達部材の前記先端部分に固定されたアブレーション要素であって、長軸に沿って直線状に配列され、相互に螺旋状に設けられた機能的に別個の複数の螺旋トランスデューサセグメントに分割された超音波トランスデューサを有する、前記アブレーション要素と、を含む、アブレーションカテーテル組立体。
Claims (20)
- 円筒超音波トランスデューサにおいて、
円筒内側電極と、
前記内側電極の上に配置された円筒圧電材料と、
前記円筒圧電材料の上に配置された円筒外側電極であって、前記円筒外側電極を複数の別個の螺旋要素に分割する螺旋溝を有する、前記円筒外側電極と、
を含み、
前記螺旋要素のそれぞれは独立して駆動されるように構成されている、円筒超音波トランスデューサ。 - 請求項1に記載の円筒超音波トランスデューサにおいて、
前記内側電極が金属層を含む、円筒超音波トランスデューサ。 - 請求項2に記載の円筒超音波トランスデューサにおいて、
前記金属層がニッケルを含む、円筒超音波トランスデューサ。 - 請求項2に記載の円筒超音波トランスデューサにおいて、
前記金属層が金を含む、円筒超音波トランスデューサ。 - 請求項1に記載の円筒超音波トランスデューサにおいて、
前記円筒圧電材料が、高密度微粒子PZTセラミック材料を含む、円筒超音波トランスデューサ。 - 請求項1に記載の円筒超音波トランスデューサにおいて、
前記円筒圧電材料が、10μmの鏡面仕上げに研磨されている、円筒超音波トランスデューサ。 - 請求項1に記載の円筒超音波トランスデューサにおいて、
前記外側電極が金属層を含む、円筒超音波トランスデューサ。 - 請求項7に記載の円筒超音波トランスデューサにおいて、
前記金属層がニッケルを含む、円筒超音波トランスデューサ。 - 請求項7に記載の円筒超音波トランスデューサにおいて、
前記金属層が金を含む、円筒超音波トランスデューサ。 - 請求項1に記載の円筒超音波トランスデューサにおいて、
前記別個の螺旋要素が相互に絡み合っている、円筒超音波トランスデューサ。 - 請求項1に記載の円筒超音波トランスデューサにおいて、
前記螺旋溝が、前記圧電材料を実質的に別個の複数のゾーンにさらに分離している、円筒超音波トランスデューサ。 - 請求項11に記載の円筒超音波トランスデューサにおいて、
前記ゾーンが、螺旋状であって相互に絡み合っている、円筒超音波トランスデューサ。 - 請求項1に記載の円筒超音波トランスデューサにおいて、
前記外側電極の上に配置された整合層を更に含む、円筒超音波トランスデューサ。 - 請求項13に記載の円筒超音波トランスデューサにおいて、
前記整合層が前記溝を満たしている、円筒超音波トランスデューサ。 - 請求項13に記載の円筒超音波トランスデューサにおいて、
前記整合層が低粘度ポリマーを含む、円筒超音波トランスデューサ。 - 請求項15に記載の円筒超音波トランスデューサにおいて、
前記ポリマーがエポキシ接着剤である、円筒超音波トランスデューサ。 - 請求項1から16のいずれか1つに記載の円筒超音波トランスデューサにおいて、前記螺旋溝はさらに、前記外側電極を分断して、前記円筒圧電材料の少なくとも一部まで延びており、前記螺旋溝は、前記トランスデューサを、機能的に別個の複数の螺旋トランスデューサセグメントに分割している円筒超音波トランスデューサ。
- 長軸に沿って直線状に配列され、複数のトランスデューサを含んでいるアブレーション要素であって、
前記トランスデューサは、請求項1から17のいずれか1つに記載のトランスデューサである、アブレーション要素。 - 請求項1から17のいずれか1つに記載の超音波トランスデューサを含んでいるアブレーション要素であって、
複数の螺旋トランスデューサセグメントは、長軸に沿って直線状に配列されている、アブレーション要素。 - 体腔における組織の領域をアブレーションするためのアブレーションカテーテル組立体において、
基端部分および先端部分を有する細長い送達部材と、
前記細長い送達部材の前記先端部分に結合されたアンカー機構であって、前記体腔における組織の実質的な部分に係合するように構成された、前記アンカー機構と、
前記細長い送達部材の前記先端部分に固定された、請求項19に記載のアブレーション要素と、
を含む、アブレーションカテーテル組立体。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/624,151 US7670335B2 (en) | 2003-07-21 | 2003-07-21 | Ablation device with spiral array ultrasound transducer |
PCT/US2004/023213 WO2005009218A2 (en) | 2003-07-21 | 2004-07-20 | Ablation device with spiral array ultrasound transducer |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006528035A JP2006528035A (ja) | 2006-12-14 |
JP4588703B2 true JP4588703B2 (ja) | 2010-12-01 |
Family
ID=34079933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006521172A Active JP4588703B2 (ja) | 2003-07-21 | 2004-07-20 | 螺旋配列超音波トランスデューサを備えたアブレーション装置 |
Country Status (6)
Country | Link |
---|---|
US (1) | US7670335B2 (ja) |
EP (1) | EP1646326B1 (ja) |
JP (1) | JP4588703B2 (ja) |
AU (1) | AU2004258943B2 (ja) |
CA (1) | CA2533537C (ja) |
WO (1) | WO2005009218A2 (ja) |
Families Citing this family (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6702811B2 (en) | 1999-04-05 | 2004-03-09 | Medtronic, Inc. | Ablation catheter assembly with radially decreasing helix and method of use |
US8241274B2 (en) | 2000-01-19 | 2012-08-14 | Medtronic, Inc. | Method for guiding a medical device |
US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
US20140018880A1 (en) | 2002-04-08 | 2014-01-16 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for monopolar renal neuromodulation |
US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
US20040082859A1 (en) | 2002-07-01 | 2004-04-29 | Alan Schaer | Method and apparatus employing ultrasound energy to treat body sphincters |
WO2005041748A2 (en) | 2003-09-12 | 2005-05-12 | Minnow Medical, Llc | Selectable eccentric remodeling and/or ablation of atherosclerotic material |
US9713730B2 (en) | 2004-09-10 | 2017-07-25 | Boston Scientific Scimed, Inc. | Apparatus and method for treatment of in-stent restenosis |
US8396548B2 (en) | 2008-11-14 | 2013-03-12 | Vessix Vascular, Inc. | Selective drug delivery in a lumen |
EP1791482B1 (en) * | 2004-09-13 | 2011-06-08 | Biosense Webster, Inc. | Ablation device with phased array ultrasound transducer |
EP2305124B1 (en) * | 2004-09-21 | 2012-01-25 | Olympus Corporation | Ultrasonic transducer array |
WO2006063199A2 (en) | 2004-12-09 | 2006-06-15 | The Foundry, Inc. | Aortic valve repair |
US8019435B2 (en) | 2006-05-02 | 2011-09-13 | Boston Scientific Scimed, Inc. | Control of arterial smooth muscle tone |
US20080039746A1 (en) | 2006-05-25 | 2008-02-14 | Medtronic, Inc. | Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions |
CA2666663C (en) | 2006-10-18 | 2016-02-09 | Minnow Medical, Inc. | System for inducing desirable temperature effects on body tissue |
AU2007310986B2 (en) | 2006-10-18 | 2013-07-04 | Boston Scientific Scimed, Inc. | Inducing desirable temperature effects on body tissue |
JP5312337B2 (ja) | 2006-10-18 | 2013-10-09 | べシックス・バスキュラー・インコーポレイテッド | 標的組織の選択的な処置のための調節されたrfエネルギーおよび電気的な組織の特徴付け |
US20080146937A1 (en) * | 2006-12-14 | 2008-06-19 | General Electric Company | Mechanically expanding transducer assembly |
US8568318B2 (en) * | 2007-02-16 | 2013-10-29 | Los Alamos National Security, Llc | High-resolution wave-theory-based ultrasound reflection imaging using the split-step fourier and globally optimized fourier finite-difference methods |
US9474571B2 (en) * | 2007-10-15 | 2016-10-25 | Boston Scientific Scimed, Inc. | Percutaneous tissue ablation probe with occlusive bodies |
US20090230823A1 (en) * | 2008-03-13 | 2009-09-17 | Leonid Kushculey | Operation of patterned ultrasonic transducers |
ES2659322T3 (es) * | 2008-07-27 | 2018-03-14 | Pi-R-Squared Ltd. | Fracturación de calcificaciones en válvulas cardíacas |
CN102271603A (zh) | 2008-11-17 | 2011-12-07 | 明诺医学股份有限公司 | 得知或未得知组织形态的选择性能量积累 |
EP2376011B1 (en) | 2009-01-09 | 2019-07-03 | ReCor Medical, Inc. | Apparatus for treatment of mitral valve insufficiency |
US8709006B2 (en) * | 2009-04-14 | 2014-04-29 | Old Dominion Research Foundation | System and method for applying plasma sparks to tissue |
EP3132828B1 (en) | 2009-10-30 | 2017-10-11 | ReCor Medical, Inc. | Apparatus for treatment of hypertension through percutaneous ultrasound renal denervation |
EP2555699B1 (en) | 2010-04-09 | 2019-04-03 | Vessix Vascular, Inc. | Power generating and control apparatus for the treatment of tissue |
US9192790B2 (en) | 2010-04-14 | 2015-11-24 | Boston Scientific Scimed, Inc. | Focused ultrasonic renal denervation |
US8473067B2 (en) | 2010-06-11 | 2013-06-25 | Boston Scientific Scimed, Inc. | Renal denervation and stimulation employing wireless vascular energy transfer arrangement |
US9358365B2 (en) | 2010-07-30 | 2016-06-07 | Boston Scientific Scimed, Inc. | Precision electrode movement control for renal nerve ablation |
US9155589B2 (en) | 2010-07-30 | 2015-10-13 | Boston Scientific Scimed, Inc. | Sequential activation RF electrode set for renal nerve ablation |
US9084609B2 (en) | 2010-07-30 | 2015-07-21 | Boston Scientific Scime, Inc. | Spiral balloon catheter for renal nerve ablation |
US9463062B2 (en) | 2010-07-30 | 2016-10-11 | Boston Scientific Scimed, Inc. | Cooled conductive balloon RF catheter for renal nerve ablation |
US9408661B2 (en) | 2010-07-30 | 2016-08-09 | Patrick A. Haverkost | RF electrodes on multiple flexible wires for renal nerve ablation |
US20130245444A1 (en) * | 2010-09-22 | 2013-09-19 | Wavomed Ltd. | Synchronously pumped ultrasonic waves and shear wave generation by same |
US8974451B2 (en) | 2010-10-25 | 2015-03-10 | Boston Scientific Scimed, Inc. | Renal nerve ablation using conductive fluid jet and RF energy |
CA2811264C (en) | 2010-10-25 | 2020-02-25 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods |
US9220558B2 (en) | 2010-10-27 | 2015-12-29 | Boston Scientific Scimed, Inc. | RF renal denervation catheter with multiple independent electrodes |
US9028485B2 (en) | 2010-11-15 | 2015-05-12 | Boston Scientific Scimed, Inc. | Self-expanding cooling electrode for renal nerve ablation |
US9089350B2 (en) | 2010-11-16 | 2015-07-28 | Boston Scientific Scimed, Inc. | Renal denervation catheter with RF electrode and integral contrast dye injection arrangement |
US9668811B2 (en) | 2010-11-16 | 2017-06-06 | Boston Scientific Scimed, Inc. | Minimally invasive access for renal nerve ablation |
US9326751B2 (en) | 2010-11-17 | 2016-05-03 | Boston Scientific Scimed, Inc. | Catheter guidance of external energy for renal denervation |
US9060761B2 (en) | 2010-11-18 | 2015-06-23 | Boston Scientific Scime, Inc. | Catheter-focused magnetic field induced renal nerve ablation |
US9023034B2 (en) | 2010-11-22 | 2015-05-05 | Boston Scientific Scimed, Inc. | Renal ablation electrode with force-activatable conduction apparatus |
US9192435B2 (en) | 2010-11-22 | 2015-11-24 | Boston Scientific Scimed, Inc. | Renal denervation catheter with cooled RF electrode |
US20120157993A1 (en) | 2010-12-15 | 2012-06-21 | Jenson Mark L | Bipolar Off-Wall Electrode Device for Renal Nerve Ablation |
WO2012100095A1 (en) | 2011-01-19 | 2012-07-26 | Boston Scientific Scimed, Inc. | Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury |
KR101040474B1 (ko) * | 2011-01-31 | 2011-06-09 | 윤만순 | 비틀림진동모드가 가능한 전극구조를 갖는 압전진동체 및 이를 포함하는 회전형 초음파 모터 |
US20140163540A1 (en) * | 2011-02-18 | 2014-06-12 | Recor Medical, Inc. | Apparatus for effecting renal denervation using ultrasound |
AU2012283908B2 (en) | 2011-07-20 | 2017-02-16 | Boston Scientific Scimed, Inc. | Percutaneous devices and methods to visualize, target and ablate nerves |
AU2012287189B2 (en) | 2011-07-22 | 2016-10-06 | Boston Scientific Scimed, Inc. | Nerve modulation system with a nerve modulation element positionable in a helical guide |
US9186210B2 (en) | 2011-10-10 | 2015-11-17 | Boston Scientific Scimed, Inc. | Medical devices including ablation electrodes |
WO2013055815A1 (en) | 2011-10-11 | 2013-04-18 | Boston Scientific Scimed, Inc. | Off -wall electrode device for nerve modulation |
US9420955B2 (en) | 2011-10-11 | 2016-08-23 | Boston Scientific Scimed, Inc. | Intravascular temperature monitoring system and method |
US9364284B2 (en) | 2011-10-12 | 2016-06-14 | Boston Scientific Scimed, Inc. | Method of making an off-wall spacer cage |
EP2768568B1 (en) | 2011-10-18 | 2020-05-06 | Boston Scientific Scimed, Inc. | Integrated crossing balloon catheter |
EP2768563B1 (en) | 2011-10-18 | 2016-11-09 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
EP2775948B1 (en) | 2011-11-08 | 2018-04-04 | Boston Scientific Scimed, Inc. | Ostial renal nerve ablation |
WO2013074813A1 (en) | 2011-11-15 | 2013-05-23 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation monitoring |
US9119632B2 (en) | 2011-11-21 | 2015-09-01 | Boston Scientific Scimed, Inc. | Deflectable renal nerve ablation catheter |
US9265969B2 (en) | 2011-12-21 | 2016-02-23 | Cardiac Pacemakers, Inc. | Methods for modulating cell function |
AU2012358146B2 (en) | 2011-12-23 | 2015-09-17 | Boston Scientific Scimed, Inc. | Methods and apparatuses for remodeling tissue of or adjacent to a body passage |
WO2013101452A1 (en) | 2011-12-28 | 2013-07-04 | Boston Scientific Scimed, Inc. | Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements |
US9050106B2 (en) | 2011-12-29 | 2015-06-09 | Boston Scientific Scimed, Inc. | Off-wall electrode device and methods for nerve modulation |
US10660703B2 (en) | 2012-05-08 | 2020-05-26 | Boston Scientific Scimed, Inc. | Renal nerve modulation devices |
EP3181081B1 (en) | 2012-05-11 | 2022-05-04 | Medtronic Ireland Manufacturing Unlimited Company | Multi-electrode catheter assemblies for renal neuromodulation and associated systems |
CN104540465A (zh) | 2012-08-24 | 2015-04-22 | 波士顿科学西美德公司 | 带有含单独微孔隙区域的球囊的血管内导管 |
US9173696B2 (en) | 2012-09-17 | 2015-11-03 | Boston Scientific Scimed, Inc. | Self-positioning electrode system and method for renal nerve modulation |
US10549127B2 (en) | 2012-09-21 | 2020-02-04 | Boston Scientific Scimed, Inc. | Self-cooling ultrasound ablation catheter |
WO2014047411A1 (en) | 2012-09-21 | 2014-03-27 | Boston Scientific Scimed, Inc. | System for nerve modulation and innocuous thermal gradient nerve block |
CN104869930B (zh) | 2012-10-10 | 2020-12-25 | 波士顿科学国际有限公司 | 肾神经调制装置和方法 |
WO2014163987A1 (en) | 2013-03-11 | 2014-10-09 | Boston Scientific Scimed, Inc. | Medical devices for modulating nerves |
WO2014143571A1 (en) | 2013-03-11 | 2014-09-18 | Boston Scientific Scimed, Inc. | Medical devices for modulating nerves |
US11147990B2 (en) | 2013-03-12 | 2021-10-19 | Acoustic Medsystems, Inc. | Ultrasound therapy catheter with multi-chambered balloons for transluminal longitudinal positioning |
US9808311B2 (en) | 2013-03-13 | 2017-11-07 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
EP2971232A1 (en) | 2013-03-14 | 2016-01-20 | ReCor Medical, Inc. | Methods of plating or coating ultrasound transducers |
EP3111994B1 (en) | 2013-03-14 | 2020-12-02 | ReCor Medical, Inc. | Ultrasound-based neuromodulation system |
US9179974B2 (en) | 2013-03-15 | 2015-11-10 | Medtronic Ardian Luxembourg S.A.R.L. | Helical push wire electrode |
US10265122B2 (en) | 2013-03-15 | 2019-04-23 | Boston Scientific Scimed, Inc. | Nerve ablation devices and related methods of use |
CN105473090B (zh) | 2013-03-15 | 2019-05-03 | 波士顿科学国际有限公司 | 重建身体通道的组织或邻近身体通道的组织的方法及装置 |
US20140276714A1 (en) * | 2013-03-15 | 2014-09-18 | Boston Scientific Scimed, Inc. | Active infusion sheath for ultrasound ablation catheter |
WO2014143746A2 (en) * | 2013-03-15 | 2014-09-18 | Corindus, Inc. | Guide wire or working catheter with modified drive surface |
WO2014149690A2 (en) | 2013-03-15 | 2014-09-25 | Boston Scientific Scimed, Inc. | Medical devices and methods for treatment of hypertension that utilize impedance compensation |
US9943365B2 (en) | 2013-06-21 | 2018-04-17 | Boston Scientific Scimed, Inc. | Renal denervation balloon catheter with ride along electrode support |
JP2016524949A (ja) | 2013-06-21 | 2016-08-22 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 回転可能シャフトを有する腎神経アブレーション用医療装置 |
US9707036B2 (en) | 2013-06-25 | 2017-07-18 | Boston Scientific Scimed, Inc. | Devices and methods for nerve modulation using localized indifferent electrodes |
EP3016605B1 (en) | 2013-07-01 | 2019-06-05 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation |
CN105377170A (zh) | 2013-07-11 | 2016-03-02 | 波士顿科学国际有限公司 | 具有可伸展电极组件的医疗装置 |
EP3019105B1 (en) | 2013-07-11 | 2017-09-13 | Boston Scientific Scimed, Inc. | Devices for nerve modulation |
WO2015010074A1 (en) | 2013-07-19 | 2015-01-22 | Boston Scientific Scimed, Inc. | Spiral bipolar electrode renal denervation balloon |
EP3024406B1 (en) | 2013-07-22 | 2019-06-19 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation |
US10695124B2 (en) | 2013-07-22 | 2020-06-30 | Boston Scientific Scimed, Inc. | Renal nerve ablation catheter having twist balloon |
JP6159888B2 (ja) | 2013-08-22 | 2017-07-05 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 腎神経変調バルーンへの接着性を向上させたフレキシブル回路 |
US9895194B2 (en) | 2013-09-04 | 2018-02-20 | Boston Scientific Scimed, Inc. | Radio frequency (RF) balloon catheter having flushing and cooling capability |
US20150073515A1 (en) | 2013-09-09 | 2015-03-12 | Medtronic Ardian Luxembourg S.a.r.I. | Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods |
CN105530885B (zh) | 2013-09-13 | 2020-09-22 | 波士顿科学国际有限公司 | 具有气相沉积覆盖层的消融球囊 |
US11246654B2 (en) | 2013-10-14 | 2022-02-15 | Boston Scientific Scimed, Inc. | Flexible renal nerve ablation devices and related methods of use and manufacture |
WO2015057521A1 (en) | 2013-10-14 | 2015-04-23 | Boston Scientific Scimed, Inc. | High resolution cardiac mapping electrode array catheter |
AU2014334574B2 (en) | 2013-10-15 | 2017-07-06 | Boston Scientific Scimed, Inc. | Medical device balloon |
US9770606B2 (en) | 2013-10-15 | 2017-09-26 | Boston Scientific Scimed, Inc. | Ultrasound ablation catheter with cooling infusion and centering basket |
WO2015057961A1 (en) | 2013-10-18 | 2015-04-23 | Boston Scientific Scimed, Inc. | Balloon catheters with flexible conducting wires and related methods of use and manufacture |
JP2016534842A (ja) | 2013-10-25 | 2016-11-10 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 除神経フレックス回路における埋め込み熱電対 |
EP3091922B1 (en) | 2014-01-06 | 2018-10-17 | Boston Scientific Scimed, Inc. | Tear resistant flex circuit assembly |
US11000679B2 (en) | 2014-02-04 | 2021-05-11 | Boston Scientific Scimed, Inc. | Balloon protection and rewrapping devices and related methods of use |
JP6325121B2 (ja) | 2014-02-04 | 2018-05-16 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 双極電極上の温度センサの代替配置 |
US9579149B2 (en) | 2014-03-13 | 2017-02-28 | Medtronic Ardian Luxembourg S.A.R.L. | Low profile catheter assemblies and associated systems and methods |
EP3134018A1 (en) | 2014-04-24 | 2017-03-01 | Medtronic Ardian Luxembourg S.à.r.l. | Neuromodulation catheters having braided shafts and associated systems and methods |
US10751121B2 (en) | 2017-06-29 | 2020-08-25 | Biosense Webster (Israel) Ltd. | Ultrasound transducers on predetermined radii of balloon catheter |
US11167121B2 (en) | 2018-05-15 | 2021-11-09 | Cardiovascular Systems, Inc. | Intravascular pump with integrated isolated conductor(s) and methods thereof |
CA3131132A1 (en) | 2019-03-01 | 2020-09-10 | Rampart Health, L.L.C. | Pharmaceutical composition combining immunologic and chemotherapeutic method for the treatment of cancer |
US20210128106A1 (en) * | 2019-11-04 | 2021-05-06 | Boston Scientific Scimed, Inc | Introducer sheath with imaging capability |
KR20230145407A (ko) | 2021-02-12 | 2023-10-17 | 램파트 헬스, 엘.엘.씨. | 암 치료를 위해 다중 면역요법과 암 백신을 조합한 치료 조성물 및 방법 |
CN115138546B (zh) * | 2022-06-29 | 2023-05-26 | 湖南大学 | 一种具有纵向复合变幅杆的超声手术刀及其设计方法 |
Family Cites Families (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3035126A (en) * | 1957-12-27 | 1962-05-15 | William W Haeffiger | Transducer |
US4135109A (en) * | 1977-09-09 | 1979-01-16 | Westinghouse Electric Corp. | High powered piezoelectric cylindrical transducer with threads cut into the wall |
US4449528A (en) | 1980-03-20 | 1984-05-22 | University Of Washington | Fast pulse thermal cautery probe and method |
US4522205A (en) | 1980-09-03 | 1985-06-11 | The University Court Of The University Of Edinburgh | Therapeutic device and method of inducing thrombosis in a blood vessel |
US4673563A (en) | 1980-10-14 | 1987-06-16 | The University Of Virginia Alumni Patents Foundation | Adenosine in the treatment of supraventricular tachycardia |
CA1244889A (en) | 1983-01-24 | 1988-11-15 | Kureha Chemical Ind Co Ltd | HYPERTHERMIA DEVICE |
US4662368A (en) | 1983-06-13 | 1987-05-05 | Trimedyne Laser Systems, Inc. | Localized heat applying medical device |
US4672962A (en) | 1983-09-28 | 1987-06-16 | Cordis Corporation | Plaque softening method |
US4569801A (en) | 1984-10-15 | 1986-02-11 | Eli Lilly And Company | Alkylsulfonamidophenylalkylamines |
US5226430A (en) | 1984-10-24 | 1993-07-13 | The Beth Israel Hospital | Method for angioplasty |
US4641649A (en) | 1985-10-30 | 1987-02-10 | Rca Corporation | Method and apparatus for high frequency catheter ablation |
US4790311A (en) | 1986-06-03 | 1988-12-13 | Ruiz Oscar F | Radio frequency angioplasty catheter system |
US4807620A (en) | 1987-05-22 | 1989-02-28 | Advanced Interventional Systems, Inc. | Apparatus for thermal angioplasty |
US4998933A (en) | 1988-06-10 | 1991-03-12 | Advanced Angioplasty Products, Inc. | Thermal angioplasty catheter and method |
US4938217A (en) | 1988-06-21 | 1990-07-03 | Massachusetts Institute Of Technology | Electronically-controlled variable focus ultrasound hyperthermia system |
US4898591A (en) | 1988-08-09 | 1990-02-06 | Mallinckrodt, Inc. | Nylon-PEBA copolymer catheter |
US5035694A (en) | 1989-05-15 | 1991-07-30 | Advanced Cardiovascular Systems, Inc. | Dilatation catheter assembly with heated balloon |
US5104393A (en) | 1989-08-30 | 1992-04-14 | Angelase, Inc. | Catheter |
US5078736A (en) | 1990-05-04 | 1992-01-07 | Interventional Thermodynamics, Inc. | Method and apparatus for maintaining patency in the body passages |
US5190540A (en) | 1990-06-08 | 1993-03-02 | Cardiovascular & Interventional Research Consultants, Inc. | Thermal balloon angioplasty |
US5178618A (en) | 1991-01-16 | 1993-01-12 | Brigham And Womens Hospital | Method and device for recanalization of a body passageway |
US5314466A (en) | 1992-04-13 | 1994-05-24 | Ep Technologies, Inc. | Articulated unidirectional microwave antenna systems for cardiac ablation |
US5562720A (en) | 1992-05-01 | 1996-10-08 | Vesta Medical, Inc. | Bipolar/monopolar endometrial ablation device and method |
US5295484A (en) | 1992-05-19 | 1994-03-22 | Arizona Board Of Regents For And On Behalf Of The University Of Arizona | Apparatus and method for intra-cardiac ablation of arrhythmias |
JPH06120062A (ja) | 1992-10-06 | 1994-04-28 | Taiyo Yuden Co Ltd | 円柱セラミックインダクタの製造方法 |
US5545161A (en) | 1992-12-01 | 1996-08-13 | Cardiac Pathways Corporation | Catheter for RF ablation having cooled electrode with electrically insulated sleeve |
US5348554A (en) | 1992-12-01 | 1994-09-20 | Cardiac Pathways Corporation | Catheter for RF ablation with cooled electrode |
US5453575A (en) * | 1993-02-01 | 1995-09-26 | Endosonics Corporation | Apparatus and method for detecting blood flow in intravascular ultrasonic imaging |
US5636634A (en) | 1993-03-16 | 1997-06-10 | Ep Technologies, Inc. | Systems using guide sheaths for introducing, deploying, and stabilizing cardiac mapping and ablation probes |
JPH06299994A (ja) | 1993-04-19 | 1994-10-25 | Matsushita Seiko Co Ltd | 多翼ファン |
US5449380A (en) | 1993-09-17 | 1995-09-12 | Origin Medsystems, Inc. | Apparatus and method for organ ablation |
US5582609A (en) | 1993-10-14 | 1996-12-10 | Ep Technologies, Inc. | Systems and methods for forming large lesions in body tissue using curvilinear electrode elements |
US5545193A (en) | 1993-10-15 | 1996-08-13 | Ep Technologies, Inc. | Helically wound radio-frequency emitting electrodes for creating lesions in body tissue |
US5575810A (en) | 1993-10-15 | 1996-11-19 | Ep Technologies, Inc. | Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like |
WO1995010322A1 (en) | 1993-10-15 | 1995-04-20 | Ep Technologies, Inc. | Creating complex lesion patterns in body tissue |
US5575766A (en) | 1993-11-03 | 1996-11-19 | Daig Corporation | Process for the nonsurgical mapping and treatment of atrial arrhythmia using catheters guided by shaped guiding introducers |
US5427119A (en) | 1993-11-03 | 1995-06-27 | Daig Corporation | Guiding introducer for right atrium |
US5564440A (en) | 1993-11-03 | 1996-10-15 | Daig Corporation | Method for mopping and/or ablation of anomalous conduction pathways |
US5487385A (en) | 1993-12-03 | 1996-01-30 | Avitall; Boaz | Atrial mapping and ablation catheter system |
US5497119A (en) | 1994-06-01 | 1996-03-05 | Intel Corporation | High precision voltage regulation circuit for programming multilevel flash memory |
US5617854A (en) | 1994-06-22 | 1997-04-08 | Munsif; Anand | Shaped catheter device and method |
US5505730A (en) | 1994-06-24 | 1996-04-09 | Stuart D. Edwards | Thin layer ablation apparatus |
US5681308A (en) | 1994-06-24 | 1997-10-28 | Stuart D. Edwards | Ablation apparatus for cardiac chambers |
US5575788A (en) | 1994-06-24 | 1996-11-19 | Stuart D. Edwards | Thin layer ablation apparatus |
EP0784453B1 (en) | 1994-10-07 | 2003-09-24 | Boston Scientific Limited | Flexible electrode support structure |
WO1996026675A1 (en) | 1995-02-28 | 1996-09-06 | Boston Scientific Corporation | Deflectable catheter for ablating cardiac tissue |
AU697414B2 (en) | 1995-04-20 | 1998-10-08 | Jawahar M. Desai | Apparatus for cardiac mapping and ablation |
US5688267A (en) | 1995-05-01 | 1997-11-18 | Ep Technologies, Inc. | Systems and methods for sensing multiple temperature conditions during tissue ablation |
US5702438A (en) | 1995-06-08 | 1997-12-30 | Avitall; Boaz | Expandable recording and ablation catheter system |
US5590657A (en) | 1995-11-06 | 1997-01-07 | The Regents Of The University Of Michigan | Phased array ultrasound system and method for cardiac ablation |
US5735811A (en) * | 1995-11-30 | 1998-04-07 | Pharmasonics, Inc. | Apparatus and methods for ultrasonically enhanced fluid delivery |
US5725494A (en) * | 1995-11-30 | 1998-03-10 | Pharmasonics, Inc. | Apparatus and methods for ultrasonically enhanced intraluminal therapy |
US5800482A (en) | 1996-03-06 | 1998-09-01 | Cardiac Pathways Corporation | Apparatus and method for linear lesion ablation |
US6063077A (en) | 1996-04-08 | 2000-05-16 | Cardima, Inc. | Linear ablation device and assembly |
US5882346A (en) | 1996-07-15 | 1999-03-16 | Cardiac Pathways Corporation | Shapable catheter using exchangeable core and method of use |
US5722403A (en) | 1996-10-28 | 1998-03-03 | Ep Technologies, Inc. | Systems and methods using a porous electrode for ablating and visualizing interior tissue regions |
US6024740A (en) | 1997-07-08 | 2000-02-15 | The Regents Of The University Of California | Circumferential ablation device assembly |
US5971983A (en) | 1997-05-09 | 1999-10-26 | The Regents Of The University Of California | Tissue ablation device and method of use |
US6012457A (en) | 1997-07-08 | 2000-01-11 | The Regents Of The University Of California | Device and method for forming a circumferential conduction block in a pulmonary vein |
US5938660A (en) | 1997-06-27 | 1999-08-17 | Daig Corporation | Process and device for the treatment of atrial arrhythmia |
US6500174B1 (en) * | 1997-07-08 | 2002-12-31 | Atrionix, Inc. | Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member |
AU741167B2 (en) | 1997-07-08 | 2001-11-22 | Atrionix, Inc. | Circumferential ablation device assembly and method |
US6117101A (en) * | 1997-07-08 | 2000-09-12 | The Regents Of The University Of California | Circumferential ablation device assembly |
DE19814697C1 (de) | 1998-04-01 | 1999-10-21 | Doru Constantin Lupasco | Piezoelektrischer Aktor und Verfahren zu seiner Herstellung |
ATE365058T1 (de) * | 1999-03-02 | 2007-07-15 | Atrionix Inc | Atriale ablationsvorrichtung mit ballon und sensor |
AU5468301A (en) | 2000-03-15 | 2001-09-24 | Boston Scientific Limited | Ablation and imaging catheter |
AU2001255845A1 (en) * | 2000-07-28 | 2002-02-13 | The Penn State Research Foundation | A process for fabricating hollow electroactive devices |
US7247269B2 (en) * | 2003-07-21 | 2007-07-24 | Biosense Webster, Inc. | Method for making a spiral array ultrasound transducer |
-
2003
- 2003-07-21 US US10/624,151 patent/US7670335B2/en not_active Expired - Lifetime
-
2004
- 2004-07-20 JP JP2006521172A patent/JP4588703B2/ja active Active
- 2004-07-20 WO PCT/US2004/023213 patent/WO2005009218A2/en active Application Filing
- 2004-07-20 CA CA2533537A patent/CA2533537C/en not_active Expired - Fee Related
- 2004-07-20 AU AU2004258943A patent/AU2004258943B2/en not_active Ceased
- 2004-07-20 EP EP04778623.1A patent/EP1646326B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA2533537A1 (en) | 2005-02-03 |
CA2533537C (en) | 2013-04-02 |
EP1646326A4 (en) | 2008-09-03 |
AU2004258943A1 (en) | 2005-02-03 |
US7670335B2 (en) | 2010-03-02 |
AU2004258943B2 (en) | 2009-09-03 |
WO2005009218A2 (en) | 2005-02-03 |
EP1646326A2 (en) | 2006-04-19 |
WO2005009218A3 (en) | 2005-06-09 |
EP1646326B1 (en) | 2013-08-21 |
US20050021015A1 (en) | 2005-01-27 |
JP2006528035A (ja) | 2006-12-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4588703B2 (ja) | 螺旋配列超音波トランスデューサを備えたアブレーション装置 | |
JP4685013B2 (ja) | 螺旋配列超音波トランスデューサの製造方法 | |
JP2006528888A5 (ja) | ||
AU2005310276B2 (en) | Ablation device with phased array ultrasound transducer | |
US6752805B2 (en) | Surgical ablation probe for forming a circumferential lesion | |
US6383151B1 (en) | Circumferential ablation device assembly | |
AU741167B2 (en) | Circumferential ablation device assembly and method | |
US6607502B1 (en) | Apparatus and method incorporating an ultrasound transducer onto a delivery member | |
US20050171527A1 (en) | Circumferential ablation device assembly with an expandable member | |
AU2001266824A1 (en) | Surgical ablation probe for forming a circumferential lesion | |
MXPA06000858A (en) | Ablation device with spiral array ultrasound transducer | |
MXPA06000857A (en) | Method for making a spiral array ultrasound transducer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070719 |
|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20071203 |
|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20080929 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100223 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100521 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100528 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100621 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100810 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20100908 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 4588703 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130917 Year of fee payment: 3 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |