JP4535468B2 - 心臓内薬物送達 - Google Patents

心臓内薬物送達 Download PDF

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Publication number
JP4535468B2
JP4535468B2 JP54819699A JP54819699A JP4535468B2 JP 4535468 B2 JP4535468 B2 JP 4535468B2 JP 54819699 A JP54819699 A JP 54819699A JP 54819699 A JP54819699 A JP 54819699A JP 4535468 B2 JP4535468 B2 JP 4535468B2
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JP
Japan
Prior art keywords
catheter
drug
heart
needle
heart wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP54819699A
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English (en)
Japanese (ja)
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JP2002516587A (ja
JP2002516587A5 (es
Inventor
ベン・ハイム，シユロモ
ヤロン，ウリ
マトコビチ，アブラハム
Original Assignee
バイオセンス・ウエブスター・インコーポレーテツド
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Publication of JP2002516587A5 publication Critical patent/JP2002516587A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A61N1/0565—Electrode heads
    • A61N1/0568—Electrode heads with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
    • A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • A61B5/062—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using magnetic field
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B18/24—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor with a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00243—Type of minimally invasive operation cardiac
    • A61B2017/00247—Making holes in the wall of the heart, e.g. laser Myocardial revascularization
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A61B2018/00392—Transmyocardial revascularisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7285—Specific aspects of physiological measurement analysis for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082—Catheter tip comprising a tool
    • A61M25/0084—Catheter tip comprising a tool being one or more injection needles
    • A61M2025/0089—Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A61N1/057—Anchoring means; Means for fixing the head inside the heart
    • A61N2001/058—Fixing tools
JP54819699A 1998-02-05 1998-02-05 心臓内薬物送達 Expired - Lifetime JP4535468B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/002195 WO1999039624A1 (en) 1998-02-05 1998-02-05 Intracardiac drug delivery

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007139899A Division JP4607920B2 (ja) 2007-05-28 2007-05-28 心臓内薬物送達

Publications (3)

Publication Number Publication Date
JP2002516587A JP2002516587A (ja) 2002-06-04
JP2002516587A5 JP2002516587A5 (es) 2005-10-06
JP4535468B2 true JP4535468B2 (ja) 2010-09-01

Family

ID=22266340

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54819699A Expired - Lifetime JP4535468B2 (ja) 1998-02-05 1998-02-05 心臓内薬物送達

Country Status (2)

Country Link
JP (1) JP4535468B2 (es)
WO (1) WO1999039624A1 (es)

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US8079982B1 (en) 1998-06-04 2011-12-20 Biosense Webster, Inc. Injection catheter with needle electrode
US6540725B1 (en) 1998-06-04 2003-04-01 Biosense Webster, Inc. Injection catheter with controllably extendable injection needle
EP1140278B1 (en) * 1998-12-14 2004-05-19 Tre Esse Progettazione Biomedica S.r.l Catheter system for performing intramyocardiac therapeutic treatment
US6319230B1 (en) 1999-05-07 2001-11-20 Scimed Life Systems, Inc. Lateral needle injection apparatus and method
US6689103B1 (en) 1999-05-07 2004-02-10 Scimed Life System, Inc. Injection array apparatus and method
US6676679B1 (en) 1999-11-05 2004-01-13 Boston Scientific Corporation Method and apparatus for recurrent demand injury in stimulating angiogenesis
US6748258B1 (en) 1999-11-05 2004-06-08 Scimed Life Systems, Inc. Method and devices for heart treatment
EP1235526A1 (en) * 1999-12-02 2002-09-04 Baxter International Inc. Methods and apparatus for delivering medicament to tissue
US6613026B1 (en) 1999-12-08 2003-09-02 Scimed Life Systems, Inc. Lateral needle-less injection apparatus and method
US6344027B1 (en) 1999-12-08 2002-02-05 Scimed Life Systems, Inc. Needle-less injection apparatus and method
US6487450B1 (en) 2000-02-24 2002-11-26 Cedars-Sinai Medical Center System and method for preventing Sudden Cardiac Death by nerve sprouting from right stellate ganglion
US6510336B1 (en) * 2000-03-03 2003-01-21 Intra Medical Imaging, Llc Methods and devices to expand applications of intraoperative radiation probes
WO2001070117A2 (en) 2000-03-23 2001-09-27 Microheart, Inc. Pressure sensor for therapeutic delivery device and method
US7214223B2 (en) 2000-03-24 2007-05-08 Boston Scientific Scimed, Inc. Photoatherolytic catheter apparatus and method
US6613025B1 (en) 2000-05-25 2003-09-02 Scimed Life Systems, Inc. Method and apparatus for diagnostic and therapeutic agent delivery
US7588554B2 (en) 2000-06-26 2009-09-15 Boston Scientific Scimed, Inc. Method and apparatus for treating ischemic tissue
US6893421B1 (en) 2000-08-08 2005-05-17 Scimed Life Systems, Inc. Catheter shaft assembly
US6595958B1 (en) 2000-08-08 2003-07-22 Scimed Life Systems, Inc. Tortuous path injection device and method
US6613017B1 (en) 2000-08-08 2003-09-02 Scimed Life Systems, Inc. Controlled depth injection device and method
WO2002072176A1 (en) * 2001-03-14 2002-09-19 Scimed Life Systems, Inc. Intervention heart catheter with locating means and method
EP1367947B1 (en) * 2001-03-14 2008-01-16 Boston Scientific Scimed, Inc. Apparatus for treatment of atrial fibrillation
US7776025B2 (en) * 2001-10-29 2010-08-17 Edwards Lifesciences Corporation Method for providing medicament to tissue
AU2002952663A0 (en) * 2002-11-14 2002-11-28 Western Sydney Area Health Service An intramural needle-tipped surgical device
AU2003276673A1 (en) * 2002-11-18 2004-06-15 Mediguide Ltd. Method and system for mounting an mps sensor on a catheter
US8862204B2 (en) 2002-11-18 2014-10-14 Mediguide Ltd. Reducing mechanical stress on conductors and connection points in a position determinable interventional medical device
US20050021091A1 (en) * 2003-04-23 2005-01-27 Laske Timothy G. System for the delivery of a biologic therapy with device monitoring and back-up
US6994094B2 (en) 2003-04-29 2006-02-07 Biosense, Inc. Method and device for transseptal facilitation based on injury patterns
US20040220461A1 (en) * 2003-04-29 2004-11-04 Yitzhack Schwartz Transseptal facilitation using sheath with electrode arrangement
US20040220471A1 (en) * 2003-04-29 2004-11-04 Yitzhack Schwartz Method and device for transseptal facilitation using location system
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
FR2862521B1 (fr) * 2003-11-24 2006-09-22 Juan Carlos Chachques Catheter de diagnostic et d'injection, notamment pour application cardiologique a coeur battant
US7725178B2 (en) 2004-06-30 2010-05-25 Cedars-Sinai Medical Center Method and system for the prediction of cardiac arrhythmias, myocardial ischemia, and other diseased condition of the heart associated with elevated sympathetic neural discharges
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
US7691086B2 (en) 2005-06-14 2010-04-06 Tengiz Tkebuchava Catheter for introduction of medications to the tissues of a heart or other organ
US7822474B2 (en) 2005-11-30 2010-10-26 Cedars-Sinai Medical Center Methods for the prediction of arrhythmias and prevention of sudden cardiac death
RU2011114561A (ru) * 2008-10-10 2012-11-20 Милакс Холдинг Са (Lu) Ввод лекарственных препаратов
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
DE102011005069B4 (de) * 2011-03-03 2014-07-03 Beauty Lumis GmbH Vorrichtung und Verfahren zur kosmetisch-ästhetischen Hautbehandlung
EP2861238A4 (en) 2012-06-05 2016-03-16 Capricor Inc OPTIMIZED METHODS FOR GENERATING CARDIAC STEM CELLS FROM CARDIAC TISSUE AND THEIR USE IN CARDIAC THERAPY
CA2881394A1 (en) 2012-08-13 2014-02-20 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
US11357799B2 (en) 2014-10-03 2022-06-14 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
US11253551B2 (en) 2016-01-11 2022-02-22 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
US11351200B2 (en) 2016-06-03 2022-06-07 Cedars-Sinai Medical Center CDC-derived exosomes for treatment of ventricular tachyarrythmias
EP3515459A4 (en) 2016-09-20 2020-08-05 Cedars-Sinai Medical Center CELLS DERIVED FROM CARDIOSPHERES AND THEIR EXTRACELLULAR VESICLES TO DELAY OR REVERSE AGING AND AGE-RELATED DISORDERS
EP3541460B1 (en) * 2016-11-21 2020-12-23 Cardiac Pacemakers, Inc. Delivery devices and wall apposition sensing
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EP3727351A4 (en) 2017-12-20 2021-10-06 Cedars-Sinai Medical Center MODIFIED EXTRACELLULAR VESICLES FOR IMPROVED TISSUE DELIVERY

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Publication number Publication date
JP2002516587A (ja) 2002-06-04
WO1999039624A1 (en) 1999-08-12

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