JP4492744B2 - Harmful arthropod control composition - Google Patents

Description

  The present invention relates to a harmful arthropod control composition having a synergistic effect containing two active ingredients.

〔式中、Ａは置換されていてもよい不飽和の環式基を表し、ＸはＮ−ＮＯ₂またはＮ−ＣＮを表し、Ｒは水素原子、Ｃ１−Ｃ６アルキル基、フェニルＣ１−Ｃ６アルキル基、Ｃ３−Ｃ６シクロアルキル基、Ｃ２−Ｃ６アルケニル基またはＣ２−Ｃ６アルキニル基を表す。〕
で示される化合物と多数の殺虫活性成分とを含有する害虫駆除組成物に関する発明が記載され、更に一般式（Ａ）で示される化合物として３−［（２−クロロ−５−チアゾリル）メチル］−５−メチル−４−ニトロイミノテトラヒドロ−１，３，５−オキサジアジンが記載されている。 So far, various harmful arthropod control agents have been used, but it is difficult to say that they will always exhibit sufficient effects depending on the situation of use.
In Patent Document 1, the following general formula (A)

[Wherein, A represents an optionally substituted unsaturated cyclic group, X represents N—NO ₂ or N—CN, R represents a hydrogen atom, a C1-C6 alkyl group, a phenyl C1-C6 alkyl group. Group, a C3-C6 cycloalkyl group, a C2-C6 alkenyl group or a C2-C6 alkynyl group. ]
The invention relates to a pest control composition comprising a compound represented by formula (II) and a number of insecticidal active ingredients, and further includes 3-[(2-chloro-5-thiazolyl) methyl]-as a compound represented by the general formula (A). 5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine has been described.

WO 97/40692 pamphlet

  An object of the present invention is to provide a harmful arthropod control composition having excellent efficacy.

As a result of intensive studies on harmful arthropod control compositions, the present inventors have found that 1- (tetrahydrofuran-3-yl) methyl-3-methyl-2-nitroguanidine, 3-[(2-chloro-5- Thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine and a combination of one or more compounds and pyriproxyfen exert a remarkable synergistic effect. The present inventors have found that an excellent extermination effect can be exerted on various harmful arthropods by applying a lower dose, and have led to the present invention.
That is, the present invention includes the following inventions.
[Claim 1] It is characterized by comprising 3-[(2-chloro-5-thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine and pyriproxyfen as active ingredients. A composition for combating harmful arthropods,
The content of 3-[(2-chloro-5-thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine and pyriproxyfen in a weight ratio of 90:10 to 50: A composition having a ratio of 50 synergistic effects;
[Claim 2] The composition according to claim 1, wherein the harmful arthropod is an ectoparasite of the animal;
[Claim 3] The composition according to claim 1, wherein the harmful arthropod is a diptera pest;
[Claim 4] The composition according to any one of claims 1 to 3, further comprising a feed for harmful arthropods; and [Claim 5] the composition according to any one of claims 1 to 4, A method for controlling harmful arthropods characterized by treating the harmful arthropods with food or habitat.

  That is, 3-[(2-chloro-5-thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine (hereinafter sometimes referred to as the present nitroimino compound) and pyriproxy. The present invention relates to a harmful arthropod control composition (hereinafter referred to as the present invention composition) containing fen in a ratio having a synergistic effect of 90:10 to 50:50 by weight.

  The harmful arthropod control composition of the present invention exhibits a remarkable synergy, and thus exhibits an excellent control effect against various harmful arthropods by applying a lower dose.

In the composition of the present invention, the present nitroimino compound used is a compound that is known to have pest control activity in the agricultural field, and pyriproxyfen is a compound that is used as an active ingredient for household protection and agricultural pesticides. It is.
The ratio of the present nitroimino compound and pyriproxyfen in the composition of the present invention is a ratio having a synergistic effect of 90:10 to 50:50 when represented by the present nitroimino compound / pyriproxyfen (weight ratio).

Examples of harmful arthropods targeted by the present invention include, for example,
Isopoda pests such as Oniscus asellus, Armadillidium vulgare, Porcellio scaber; Diplopoda pests such as Blancilus guttulatus (a kind of millipede);
Chiropoda pests such as Geophilus carpophagus, Scutigera spp., Scolopendra subspinipes, Thereunema spp.
Symphyla pests such as Scutigerella immaculata;
Thysanura pests such as Ctenolepisma villosa and Lepisma saccharina
Psocoptera pests such as Trogium pulsatorium;
Collembola pests such as Onychiurus armatus;
The termite family (Mastotermitidae), Zootermopsis genus, Archotermopsis genus, Hodotermopsis japonica, etc. The genus Cryptotermes, such as Cryptotermes domesticus, the Incisitermes genus, such as the American termite minor (Incisitermes minor), the Glyptotermes satsumaensis, the G. nakajimai, the genus G. fustoterm, etc. Lepidoptera (Kalotermitidae), Hodotermes genus, Microhodotermes genus, Anacanthotermes genus, etc., Termite termite (Hodotermitidae), Yamato termite (Retitulitermes speratus), Cammon termite (R. sp), Common termite (R. flaviceps) Reticulitermes genus, such as R. miyatakei, Heteroterm es genus, termites (Coptotermes formosanus), etc. Coptotermes genus, Schedolinotermes, etc. Odontotermes genus, such as Odontotermes formosanus), Microtermes genus, Nasutitermes takasagoensis, etc., Nasutitermes genus, Pericapritermes nitobei, etc. pest;
Dictyoptera pests such as Blatta orientalis, Periplaneta americana, P. fuliginosa, Leucophaea maderae, Blattella germanica, etc .;
Glylotalpa spp. (A kind of kerato), Acheta domesticus (Eco cricket), Teleogryllus emma (Ema cricket), Locusta migratoria (A kind of grasshopper), Melanoplus differentialis (A kind of grasshopper), opt thracite (Orth) (Orth) (Orth) pest;
Dermaptera pests such as Labidura riparia and Forficula auricularia (a kind of rotifer);
Phthirus pubis, Pediculus humanus, Haematopinus suls, Haematopinus eurysternus, Damalinia ovis, Linognathus spp. Eye (Anoplura) pests;
Malophaga pests such as Trichodectesspp., A kind of beetle lice, Tromenopon spp., A kind of beetle larvae, Bovicola spp. (A kind of beetle lice), Felicola spp.
Thysanoptera pests such as Frankliniella intonsa, Thrips tabaci, and T. palmi;
Nezara spp. (A kind of blue stink bug), Eurygaster spp. (A kind of white stink bug), Dysdercus intermedius (a kind of stink bug), Cimex lectularius, Triatoma spp. (A kind of stink bug), Rhodnius prolixus ), Nezara antennata, Heteroptera pests such as Cletus punetiger;
Aleurocanthus spiniferus, Bemisia tabaci (Tobacco whitefly), Bemisia argentifolii (Silver leaf whitefly), Trialeurodes vaporariorum, Aphis gossypii (Cryptomeria) , Aphis fabae, Macrosiphum euphorbiae (Tulip beetle aphid), Myzus persicae (Peach aphid), Phorodon humuli, Empoasca spp. , Saissetia oleae, Laodelphax striatellus, Nilaparvata lugens, Aonidiella aurantii, Aspidiotus hederae .. Ramushi), a kind of Pseudococcus spp (mulberry mealybugs), one Psylla spp (Psyllidae), Homoptera such Phylloxera vastatrix (phylloxera) (Homoptera) pests;
Pectinophora gossypiella (cotton beetle), Lithocolletis blancardella (a kind of white-tailed beetle), Plutella xylostella (Ponus moth), Malacosoma neustria (Obikareha), Euproctis subflava (Dokuga), Lymantria dispar (Maiiga), Bucculatrix pyrhnis , Agrotis spp., Auxilia spp., Earias insulana, Heliothis spp., Spodoptera exigua, S. litura, Spodera spp. (a kind of clover), Mamestra brassicae (a kind of cormorant), Trichoplusia ni (a kind of cormorant), Carpocapsa pomonella (a kind of codling moth), Chilo spp. (a kind of cicada), Pyrausta nubilalis (maiga) ), Ephestia kuehniella, Galler Lepidoptera pests such as ia mellonella, Tineola bisselliella, Tenea translucens, Icha, Homona magnanima, Tortrix viridana, etc .;
Anobium punctatum, Rhizopertha dominica, Acanthoscelides obtectus, Agelastica alni, Leptinotarsa decemlineata, Phaedon cochleariae, D Worm), Psylliodes angusticollis, Phyllotreta striolata, Epilachna spp., Atomaria spp., Oryzaephilus surinamensis, Anyzaephilus surinamensis Beetle weevil), Sitophilus spp., Otiorhynchus sulcatus, Cosmopolites sordidus, Cethorhyncidius albosuturalis, Hypera postica ), Dermestes spp. (A kind of cutworm), Trogoderma spp., Attagenus unicolor, Lyctus dentatum, L. planicollis (L. planicollis), L. planicollis (L. planicollis) Pterus spp. (Lyctridae), Melitethes aeneus, Ptinus sp., Ptinus sp., Ptinus sp. (A kind of leopard beetle), Gibbium psylloides, a kind of Tribolium spp. Bark beetles of the genus Xyleborus and Scolytoplatypus (S colytidae), Monochamus genus, Hylotrupes genus, Hesperophanus genus, Chlorophorus genus, Palaeocallidium genus, Semanotus genus, Purpuricenus genus, Stromatium genus, etc. , Bostrychus, Sinoderus genus, etc. Coleoptera pests;
Diprion spp. (A kind of wasps), Hoplocampa spp. (A kind of wasps), Lasius spp. (A kind of black ants), Formica japonica (a kind of wasps), Vespa spp. (A kind of wasp), Urocerus genus, Sirex genus, etc. Hymenoptera pests such as Siricidae;
Aedes spp. (A kind of mosquito), Anopheles spp. (A kind of anopheles), Culex spp. (A kind of housefly), Drosophila melanogaster (A kind of fruit fly), Musca domestica (A kind of housefly), Fania spp. (A kind of housefly) Calliphora spp., Lucilia spp., Chrysomyaspp., Cuterebra spp., Gastrophilus spp., Stomoxys spp., Oestrus spp. (a kind of sheep flies), Hypoderma spp. (a kind of cow fly), Tabanus spp. (a kind of fly), Bibio hortulanus (a kind of fly fly), Pegomyia hyoscyami (a kind of fly fly), Ceratitis capitata (Daphnia fruit fly), Dacus dors (Spotted fruit fly), Tipula paludosa (type of Crane fly), Simulium spp. (Type of flyfish), Eusimulium spp., Phlebotomus spp. (Type of sandfly), Culicoides spp. (a kind of leafhopper), Chrysops spp. (a kind of melabu), Haematopota spp. (a kind of honeyflies), Braula spp. Diptera such as tsetse fly), Wohlfahrtia spp., Sarcophaga spp., Lipoptena spp., Melophagus spp., Muscina spp. (A kind of fruit fly) Diptera) pests;
Siphonaptera pests such as Xenopsylla cheopis, Ctenocephalides felis, Catenocephalides canis, Ceratophyllus spp., Pulex spp.
Arachnida pests such as Scorpio maurus, Latrodectus mactans, Chiracanthiumspp.
Otodectes spp., Acarus siro, Argas spp., Ornithodoros spp., Ornithonyssus spp., Dermanyssus spp., Dermanyssus spp. ), Eriophyes spp. (A kind of acarid tick), Haemaphyxalis longicornis (a kind of spider mite), Boophilus microplus (a kind of mite), Rhipicephalus spp. (Spotted spider mite), Ixodes ovatus (spotted tick), Ixodes persulcatus (shulzeid tick), Psoroptes equi (spotted spider mite), Chorioptes spp. (Spotted spider mite), Sarcoptes spp. (Spotted spider mite), Tarsonemus spp. (A type of dust mite), Bryobia praetiosa, Panonychus spp. Acarapis, Tetranychus spp., Dermacentor spp., Haemaphysalis spp., Raillietia spp., Pneumonyssus spp., Sternostorma spp., Acarapis spp. (a kind of acarid mite), Cheyletiella spp. (a kind of acarid mite), Myobia spp. (a kind of acarid mite), Psorergates spp. (a kind of acarid tick), Demodex xp. (A kind of tsutsugamushi), Listrophorus spp. (A kind of acarid mite), Tyrophagus spp. (A kind of acarid mite), Sarcoptes spp. (A kind of dung beetle mite), Notoedres spp. Acarina pests such as a kind of acarid mite and Laminosioptes spp.

In particular, ectoparasites of animals such as cattle and sheep, and animals such as dogs and cats, such as Musca hervei, Musca bezzii, Musca domestica, Haematobia irritans, Diptera pests such as Simulium iwatens, Culicoides oxystoma, Boban ab (Tabanus chrysurus), Culex pipiens, Aedes albopictus, etc.
Lice insect pests such as cattle lice (Haematopinus eurysternus), sheep lice (Damalinia ovis), Haemaphyxalis longicornis, tick (Haemaphysalis japonica), tick (Dermacentorrecticula tick), Dermacentorrecticula tick Ixodes ovatus), Schulze ticks (Ixodes persulcatus), Ticks (Boophilus microplus), etc.
It is suitable for controlling flea pests such as cat fleas (Ctenocephalides felis), dog fleas (Ctenocephalides canis) and Xenopsylla cheopis.
In addition, house insects such as Drosophila melanogaster, Clogmia albipunctata, Chironomus yoshimatsui, Megaselia spiracularis, Drosophila melanogaster,
Straight insects such as German cockroaches (Blattella germanica), black cockroaches (Periplaneta fuliginosa), American cockroach (Periplaneta americana),
Mite pests such as house dust mite (Ornithonyssus bacoti), southern mite (Chelacaropsis moorei),
Lepidopterous pests such as tiger (Tinea translusens) and moth (Tineola bisselliella),
Lice insects such as head lice (Pediculus humanus humanus), lice (Phthiruspubis),
Coleopterous insects such as Anthrenus verbasci, Attagenus unicolor, Tobacco insect (Lasioderma serricorne),
It is suitable for the control of hygienic pests such as Hymenoptera, Monomorium pharanonis and Monomorium intrudens.

  The composition of the present invention may be composed only of the present nitroimino compound and pyriproxyfen, but is practically used as a preparation that appropriately contains a solid carrier, a liquid carrier, a formulation adjuvant and the like. Formulations include emulsions, oils, spot-on agents, pour-on agents, shampoos, suspensions and other liquids, powders, wettable powders, granules, paste-form preparations, microencapsulated preparations, foams, aerosol preparations, carbonic acid Gas preparations, tablets, sheet preparations, resin preparations and the like can be mentioned, and a preferable preparation form is appropriately selected upon application.

  Moreover, although content of this nitroimino compound and pyriproxyfen can change with the formulation forms, it is 0.005-50 weight% normally in a total amount.

  These preparations can be further prepared by mixing the present nitroimino compound and pyriproxyfen with a solid carrier or liquid carrier, and if necessary, adding and mixing other formulation adjuvants such as emulsifiers and sticking agents. Depending on the form, it can be obtained by molding. Examples of carriers and adjuvants used in the preparation include the following.

  Examples of the solid carrier include natural materials such as clay, kaolin, talc, bentonite, sericite, quartz, sulfur, activated carbon, calcium carbonate, diatomaceous earth, pumice, calcite, gypsum, dolomite, silica, alumina, vermiculite, and pearlite. Alternatively, synthetic minerals, sawdust, corn cobs, coconut husks, fine granules such as tobacco stems, gelatin, petrolatum, methylcellulose, lanolin, lard, liquid paraffin and the like can be mentioned. Examples of the liquid carrier include aromatic or aliphatic hydrocarbons such as xylene, toluene, alkylnaphthalene, phenylxylylethane, kerosene, light oil, hexane, and cyclohexane, and halogenated hydrocarbons such as chlorobenzene, dichloromethane, dichloroethane, and trichloroethane. Alcohols such as methanol, ethanol, isopropyl alcohol, butanol, hexanol, ethylene glycol, ethers such as diethyl ether, ethylene glycol dimethyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, propylene glycol monomethyl ether, tetrahydrofuran, dioxane, acetic acid Esters such as ethyl and butyl acetate, acetone, methyl ethyl ketone, methyl isobuty Ketones such as ketone and cyclohexanone, nitriles such as acetonitrile and isobutyronitrile, sulfoxides such as dimethyl sulfoxide, acid amides such as N, N-dimethylformamide and N, N-dimethylacetamide, soybean oil, cottonseed oil, etc. Vegetable oil, orange oil, hyssop oil, lemon essential oil and other essential oils, and water. Examples of the propellant in foams, aerosol preparations and carbon dioxide preparations include propane gas, butane gas, freon gas, liquefied petroleum gas, dimethyl ether, carbon dioxide gas and the like.

  Examples of the base material of the resin preparation include vinyl chloride polymers and polyurethanes. These base materials include phthalic acid esters (dimethyl phthalate, dioctyl phthalate, etc.), adipic acid as necessary. Plasticizers such as esters and stearic acid are added. It can be obtained by kneading the active ingredient compound in the substrate using a conventional kneading apparatus and then molding by injection molding, extrusion molding, press molding or the like. If necessary, it can be processed into resin preparations such as plates, films, tapes, nets, strings, etc. by passing through processes such as molding and cutting, such as animal collars, animal ear tags, and sheets. It can also be used as an agent, an attraction string, a packaging film, or a gardening support.

  Examples of the adjuvant for preparation include nonionic emulsifiers such as polyoxyethylene fatty acid ester and polyoxyethylene fatty acid alcohol ether, ionic emulsifiers such as alkyl sulfonate, alkyl sulfate, and aryl sulfonate, Dispersants such as lignin sulfonate, methylcellulose, fixing agents such as carboxymethylcellulose, gum arabic, polyvinyl alcohol, polyvinyl acetate, iron oxide, titanium oxide, Prussian blue, alizarin dye, azo dye, phthalocyanine dye and other colorants Can be mentioned.

  In addition, this invention composition can also contain active ingredients other than this nitroimino compound and pyriproxyfen suitably. Examples of active ingredients other than the nitroimino compound and pyriproxyfen include, for example, pyrethroid compounds such as permethrin, phenothrin, allethrin, pyrethrin, praretrin, ciphenothrin, cyfluthrin, fenvalerate, fenpropatoline, transfluthrin, dichlorvos, tetrachlorophene, etc. Organic phosphorus compounds such as robinphos, fenthion, chlorpyrifos, diazinon, carbamate compounds such as propoxyl, carbaryl, methoxadiazone, fenobucarb, lufenuron, chlorfluazuron, hexaflumuron, cyromazine, 1- (2,6-difluorobenzoyl)- Chitin formation inhibitors such as 3- [2-fluoro-4- (1,1,2,3,3,3-hexafluoropropoxy) phenyl] urea, metoprene, and hide Juvenile hormone-like substances such as loprene and phenoxycarb, N-phenylpyrazole compounds, milbemycin, abamectin, ivermectin and other animal endoparasiticides, N, N-diethyl-m-triamide (Deet), limonene, linalool, Pest repellents such as citronellal, menthol, menthone, hinokitiol, geraniol, eucalyptol, indoxacarb, caran-3,4-diol, synergists such as PBO, S421, MGK264, IBTA, sinepiline 500, etc. Can do.

  The composition of the present invention is usually used by applying it directly to harmful arthropods or in its habitat (plants, animals, soil, etc.), etc., but it is mixed in covered electric wires, synthetic resin sheets, etc. It can be used for the manufacture of various products treated with insect repellent. When the composition of the present invention is used for home protection, for example, when controlling indoor flies and mosquitoes, the amount of active ingredient (in this specification, “the amount of active ingredient”, unless otherwise specified, This means the total amount of the nitroimino compound and pyriproxyfen.) Is applied in an amount of about 0.001 to 10 mg / m 3. Moreover, when controlling cockroaches, ants, etc., an effective component amount of about 0.001 to 100 mg / m 2 is applied.

  When controlling wood pests, the composition of the present invention may be applied directly to the pests, but the composition of the present invention is usually applied to wood, soil or the like where the pests live. Further, the composition of the present invention can be used for the production of plywood and wood boards by mixing it with an adhesive, or can be used for the production of various insect-proof products by mixing it with a covered electric wire or a synthetic resin sheet. The application amount varies depending on the kind of the target pest, formulation form, application place, application method, etc., but is generally about 0.1 to 10,000 mg / m @ 2 in terms of the active ingredient amount.

  When the composition of the present invention is used for controlling ectoparasites in animals such as dogs and cats, and animals such as cattle and sheep, for example, when applied to animals, the amount of active ingredient is usually 0. When applied to a surface of 1 to 1000 mg / kg, floors other than animals, outdoors, etc., usually about 0.1 to 10000 mg / m 2 is applied.

  Further, when the composition of the present invention is used for agriculture, the amount of active ingredient is usually 1 g to 1000 g / ha, preferably about 10 g to 300 g / ha. When the composition of the present invention is used as a preparation such as an emulsion, wettable powder, suspension, etc., and the preparation is diluted with water, its application concentration is usually 1 ppm to 1000 ppm, preferably 10 ppm to 200 ppm as an active ingredient. Yes, in the case of preparations such as granules and powders, they are usually applied as they are. These preparations and water dilutions of the preparations may be treated with foliage on plants such as crops to be protected from pests, or treated on the soil for the purpose of controlling the pests that inhabit the soil in the cultivated land. Also good. In addition, the resin preparation processed into a sheet shape, a string shape, or the like can be applied by directly wrapping around a crop, installing it near the crop, or laying it on the soil surface of the plant source.

Hereinafter, the present invention will be described in more detail with reference to examples.
Formulation Example 1
9 parts by weight of 1- (tetrahydrofuran-3-yl) methyl-3-methyl-2-nitroguanidine, 1 part by weight of pyriproxyfen and 90 parts by weight of diethylene glycol monomethyl ether are mixed to obtain a spot-on preparation.

Formulation Example 2
3-[(2-Chloro-5-thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazone, 10 parts by weight pyriproxyfen, polyoxyethylene alkylaryl ether 8 An emulsion is obtained by mixing 2 parts by weight of sodium alkylarylsulfonate and 75 parts by weight of xylene.

Test example 1
The spot-on formulation obtained in Formulation Example 1 was applied to the cat's neck back skin at 0.4 ml / kg against a cat (living weight 2.5-3.0 kg) previously infested with 30 cat flea adults. It was dripped. The number of parasitic fleas was counted using a flea removal comb 3 days and 7 days after the treatment. As a control, the number of cat fleas parasitized in the untreated cat was observed. The results are shown in Table 1.

Test example 2
0.1% (w / v) dissolution of 1- (tetrahydrofuran-3-yl) methyl-3-methyl-2-nitroguanidine (hereinafter referred to as Compound A) or pyriproxyfen (hereinafter referred to as Compound B) Each ethanol solution was prepared, diluted with water to prepare a 1 ppm aqueous solution of Compound A or Compound B, and then mixed in a predetermined ratio to obtain a Compound A / Compound B concentration (ppm) of 1 0.0 / 0 (compound A single agent), 0.99 / 0.01, 0.9 / 0.1, 0.8 / 0.2, 0.7 / 0.3, 0.5 / 0.5 , 0/1 (compound B single agent) was prepared (total 7 types of test solutions). 100 ml of the test solution was added to 50 g of a fly medium (mixture of bran and animal powdered feed), mixed, and placed in a 650 ml plastic cup. In a nylon net cage (width 21 cm, depth 28 cm, height 21 cm), two plastic cups containing the above medium treated with water, bait (skim milk: granulated sugar = 2: 1) and the test solution were placed. One of the two cups containing the medium contained 30 4 day-old larvae of the house fly (CSMA strain). In addition, 20 adult house flies (CSMA strain, sex ratio = 1) were released in this cage. Thereafter, the number of house flies alive in the cage was observed after 1 day, 2 days and 8 days, and the cumulative number was recorded.
As a control, a similar test was performed using a medium treated with water. The control rate, the theoretical control rate, and the synergistic effect index were determined by the following formula.
Control rate (%) = (C−T) ÷ C × 100
C: Cumulative number of live flies in control group T: Cumulative number of live flies in treated group Theoretical control rate (%) = P × Compound A compounding ratio + Q × Compound B compounding ratio P: Compound A single agent ( Control rate at 1 ppm),
Q: Control rate in compound B single agent (1 ppm) Synergistic effect index = control rate ÷ theoretical control rate × 100
The experiment was performed in duplicate. The results are shown in Table 2.

Test example 3
Instead of compound A, 3-[(2-chloro-5-thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine (hereinafter referred to as compound C) was used, and the test solution Compound C / Compound B concentration (ppm) is 1.0 / 0 (compound C single agent), 0.9 / 0.1, 0.7 / 0.3, 0.5 / 0.5, 0/1 Experiments were conducted in the same manner as in Test Example 2, except that a total of five test solutions of 0.0 ppm were used. However, the result of Test Example 2 was used for the control. The results are shown in Table 3.
The control rate and the theoretical control rate were determined using the calculation formula of Test Example 2 except that the value of Compound C was used instead of Compound A.

Comparative Test Example 1
The experiment was conducted in the same manner as in Test Example 3 except that metoprene (hereinafter referred to as comparative compound 1) was used instead of compound B. However, the result of Test Example 2 was used for the control. The results are shown in Table 4.
The control rate and the theoretical control rate were determined using the calculation formula of Test Example 2 except that the value of Comparative Compound 1 was used instead of Compound B.

Test example 4
A plastic cup planted cabbage seedling was placed in a net cage where a large number of silver leaf whitefly lived for 24 hours, and the cabbage seedling was infested with many silver leaf whitefly. Emulsion of Compound A (produced by mixing 5 parts by weight of Compound A, 9 parts by weight of Solpol 3005X (manufactured by Toho Chemical), 11 parts by weight of xylene, and 10 parts by weight of DMF), Emulsion of Compound B (trade name Ranoh emulsion: manufactured by Sumitomo Chemical) Alternatively, a predetermined amount of each of the mixture of the compound A emulsion and the compound B emulsion was diluted with water and sprayed onto the cabbage seedlings with a spray gun. Immediately before treatment and 10 days after treatment, the number of surviving insects (total number of adult and larvae) of silver leaf whitefly on the cabbage seedling was examined. As a control, a similar test was performed using cabbage seedlings treated with water.
The control rate and the theoretical control rate were determined by the following formula.
Control rate (%) = 100 × {1− (T ÷ T0) ÷ (C ÷ C0)}
T: Number of surviving insects 10 days after treatment in the treatment group T0: Number of surviving insects immediately before treatment in the treatment group C: Number of surviving insects 10 days after treatment in the control group C0: Number of surviving insects immediately before treatment in the control group Theoretical control rate ( %) = P + (100−P) × Q ÷ 100
P: Control ratio of compound A single agent (50 ppm) Q: Control ratio of compound B single agent (50 ppm) The experiment was performed in one iteration. The results are shown in Table 5.

Test Example 5
The same experiment as in Test Example 4 was performed except that Compound C was used instead of Compound A. However, the results of Test Example 4 were used for the compound B single agent and the control. The results are shown in Table 6.
The control rate and the theoretical control rate were determined using the calculation formula of Test Example 4 except that the value of Compound C was used instead of Compound A.

  The harmful arthropod control composition of the present invention exhibits an excellent control effect against various harmful arthropods and is useful for combating harmful arthropods.

Claims (5)

A harmful arthropod characterized by comprising 3-[(2-chloro-5-thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine and pyriproxyfen as active ingredients A composition for disinfection,
The content of 3-[(2-chloro-5-thiazolyl) methyl] -5-methyl-4-nitroiminotetrahydro-1,3,5-oxadiazine and pyriproxyfen in a weight ratio of 90:10 to 50: A composition having a ratio of 50 synergistic effects. The composition according to claim 1, wherein the harmful arthropod is an ectoparasite of the animal. The composition according to claim 1, wherein the harmful arthropod is a diptera pest. The composition according to any one of claims 1 to 3, further comprising a feed for harmful arthropods. A method for controlling harmful arthropods, which comprises treating the composition of any one of claims 1 to 4 with the feed or habitat of harmful arthropods.