JP4481489B2 - ヒトｉｌ−１２に対する抗体 - Google Patents
ヒトｉｌ−１２に対する抗体 Download PDFInfo
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- JP4481489B2 JP4481489B2 JP2000528602A JP2000528602A JP4481489B2 JP 4481489 B2 JP4481489 B2 JP 4481489B2 JP 2000528602 A JP2000528602 A JP 2000528602A JP 2000528602 A JP2000528602 A JP 2000528602A JP 4481489 B2 JP4481489 B2 JP 4481489B2
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| US20060084061A1 (en) * | 2002-06-11 | 2006-04-20 | Marcusson Eric G | Methods for blocking adipocyte differentiation and triglyceride accumulation with interleukin 12 p35 inhibitors |
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| US6706264B1 (en) | 1994-03-14 | 2004-03-16 | Genetics Institute, Llc | Use of IL-12 antagonists in the treatment of conditions promoted by an increase in levels of IFN-y |
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| US6914128B1 (en) | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
| US7883704B2 (en) | 1999-03-25 | 2011-02-08 | Abbott Gmbh & Co. Kg | Methods for inhibiting the activity of the P40 subunit of human IL-12 |
| US6939545B2 (en) * | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
| CA2399387C (en) * | 2000-02-11 | 2015-11-03 | Biogen, Inc. | Heterologous polypeptide of the tnf family |
| US6348316B1 (en) | 2000-04-12 | 2002-02-19 | Cedars-Sinai Medical Center | Genetic testing for determining the risk of pouchitis development |
| US8080247B2 (en) | 2000-08-07 | 2011-12-20 | Janssen Biotech, Inc. | Anti-IL-12 antibodies |
| US6902734B2 (en) | 2000-08-07 | 2005-06-07 | Centocor, Inc. | Anti-IL-12 antibodies and compositions thereof |
| US7638604B2 (en) * | 2001-02-23 | 2009-12-29 | Genetics Institute, Llc | Monoclonal antibodies against interleukin-22 |
| WO2002097048A2 (en) * | 2001-05-30 | 2002-12-05 | Centocor, Inc. | ANTI-p40 IMMUNOGLOBULIN DERIVED PROTEINS, COMPOSITIONS, METHODS AND USES |
| KR100453877B1 (ko) | 2001-07-26 | 2004-10-20 | 메덱스젠 주식회사 | 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체 |
| PT1585546E (pt) * | 2002-12-30 | 2008-11-14 | Biogen Idec Inc | Antagonistas de kim-1 e sua utilização para modular o sistema imunitário |
| CA2550155C (en) * | 2003-12-15 | 2015-03-17 | Dendreon Corporation | Hla-dr-specific antibodies, compositions and methods |
| GB0329146D0 (en) * | 2003-12-16 | 2004-01-21 | Glaxosmithkline Biolog Sa | Vaccine |
| EP1865985B1 (en) | 2005-03-02 | 2010-08-25 | Biogen Idec MA Inc. | Kim-1 antibodies for treatment of th2-mediated conditions |
| UA96922C2 (en) * | 2005-06-30 | 2011-12-26 | Эббот Леборейториз | Il-12/p40 binding protein |
| TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
| TWI417301B (zh) * | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途 |
| US7776331B1 (en) | 2007-01-16 | 2010-08-17 | Abbott Laboratories | Methods of treating plaque psoriasis |
| EP2527364A1 (en) | 2007-03-29 | 2012-11-28 | Abbott Laboratories | Crystalline anti-human IL-12 antibodies |
| NZ602511A (en) | 2008-03-18 | 2014-03-28 | Abbvie Inc | Methods for treating psoriasis |
| US8563697B2 (en) | 2008-08-14 | 2013-10-22 | Cephalon Australia Pty. Ltd. | Anti-IL-12/IL-23 antibodies |
| CN104398471A (zh) * | 2008-11-28 | 2015-03-11 | Abbvie公司 | 稳定的抗体组合物和用于稳定其的方法 |
| KR20120112384A (ko) * | 2009-09-14 | 2012-10-11 | 애보트 게엠베하 운트 콤파니 카게 | 건선을 치료하는 방법 |
| CN103275222B (zh) * | 2013-05-15 | 2014-04-16 | 中山康方生物医药有限公司 | 一种阻断白介素12 p40功能的单克隆抗体及其编码基因和应用 |
| CA3019164A1 (en) | 2016-03-29 | 2017-10-05 | Janssen Biotech, Inc. | Method of treating psoriasis with increased interval dosing of anti-il12/23 antibody |
| TW201922780A (zh) * | 2017-09-25 | 2019-06-16 | 美商健生生物科技公司 | 以抗ｉｌ１２／ｉｌ２３抗體治療狼瘡之安全且有效之方法 |
| WO2019220412A2 (en) | 2018-05-18 | 2019-11-21 | Janssen Biotech, Inc. | Safe and effective method of treating lupus with anti-il12/il23 antibody |
| FI13575Y1 (fi) | 2018-09-24 | 2024-03-26 | Janssen Biotech Inc | IL12/IL23-vasta-aine käytettäväksi turvallisessa ja tehokaassa menetelmässä haavaisen paksusuolitulehduksen hoitamiseksi |
| CA3138241A1 (en) | 2019-05-23 | 2020-11-26 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
| EP4596046A3 (en) | 2020-05-21 | 2025-10-22 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
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| CA2125763C (en) * | 1993-07-02 | 2007-08-28 | Maurice Kent Gately | P40 homodimer of interleukin-12 |
| US5536657A (en) | 1993-07-19 | 1996-07-16 | Hoffmann-La Roche Inc. | Recombinant DNA encoding human receptor for interleukin-12 |
| ZA95960B (en) * | 1994-03-14 | 1995-10-10 | Genetics Inst | Use of interleukin-12 antagonists in the treatment of autoimmune diseases |
| US7119248B1 (en) * | 1994-04-12 | 2006-10-10 | Miltenyi Biotec Gmbh | Antibodies against epitopes with homology to self antigens, methods of preparation and applications thereof |
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| US5853697A (en) * | 1995-10-25 | 1998-12-29 | The United States Of America, As Represented By The Department Of Health & Human Services | Methods of treating established colitis using antibodies against IL-12 |
| US5809360A (en) * | 1996-08-07 | 1998-09-15 | Agfa Division - Bayer Corporation | Cassette for storing and accessing plates within an automated plate handler |
| AU734758B2 (en) * | 1997-04-01 | 2001-06-21 | Sankyo Company Limited | Anti-fas antibodies |
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