JP4456754B2 - 疼痛管理のための新規な使用 - Google Patents
疼痛管理のための新規な使用 Download PDFInfo
- Publication number
- JP4456754B2 JP4456754B2 JP2000528283A JP2000528283A JP4456754B2 JP 4456754 B2 JP4456754 B2 JP 4456754B2 JP 2000528283 A JP2000528283 A JP 2000528283A JP 2000528283 A JP2000528283 A JP 2000528283A JP 4456754 B2 JP4456754 B2 JP 4456754B2
- Authority
- JP
- Japan
- Prior art keywords
- pain
- ropivacaine
- point
- preparation according
- muscle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000002193 Pain Diseases 0.000 title claims abstract description 61
- ZKMNUMMKYBVTFN-HNNXBMFYSA-N (S)-ropivacaine Chemical compound CCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C ZKMNUMMKYBVTFN-HNNXBMFYSA-N 0.000 claims abstract description 23
- 229960001549 ropivacaine Drugs 0.000 claims abstract description 21
- 238000011282 treatment Methods 0.000 claims abstract description 10
- 208000000491 Tendinopathy Diseases 0.000 claims abstract description 6
- 206010043255 Tendonitis Diseases 0.000 claims abstract description 6
- 238000007918 intramuscular administration Methods 0.000 claims abstract description 6
- 201000004415 tendinitis Diseases 0.000 claims abstract description 6
- 206010028391 Musculoskeletal Pain Diseases 0.000 claims description 9
- 150000004682 monohydrates Chemical group 0.000 claims description 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 7
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 7
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 238000002347 injection Methods 0.000 description 10
- 239000007924 injection Substances 0.000 description 10
- 210000003205 muscle Anatomy 0.000 description 8
- 238000000034 method Methods 0.000 description 6
- 238000002559 palpation Methods 0.000 description 6
- 208000000112 Myalgia Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 210000003195 fascia Anatomy 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 3
- 210000002435 tendon Anatomy 0.000 description 3
- 230000001684 chronic effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 210000004283 incisor Anatomy 0.000 description 2
- 239000003589 local anesthetic agent Substances 0.000 description 2
- 230000005923 long-lasting effect Effects 0.000 description 2
- 208000013465 muscle pain Diseases 0.000 description 2
- 210000001087 myotubule Anatomy 0.000 description 2
- 230000011514 reflex Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000002123 temporal effect Effects 0.000 description 2
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 description 1
- 206010001497 Agitation Diseases 0.000 description 1
- 208000007848 Alcoholism Diseases 0.000 description 1
- 241000557626 Corvus corax Species 0.000 description 1
- 206010013654 Drug abuse Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000001640 Fibromyalgia Diseases 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 description 1
- 208000030858 Myofascial Pain Syndromes Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000028752 abnormal posture Diseases 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 206010001584 alcohol abuse Diseases 0.000 description 1
- 208000025746 alcohol use disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 230000002567 autonomic effect Effects 0.000 description 1
- 238000012925 biological evaluation Methods 0.000 description 1
- 229960003150 bupivacaine Drugs 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000007907 direct compression Methods 0.000 description 1
- 230000000773 effect on pain Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 229960004194 lidocaine Drugs 0.000 description 1
- 210000003784 masticatory muscle Anatomy 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 208000015004 muscle tenderness Diseases 0.000 description 1
- 229940029571 naropin Drugs 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 208000027753 pain disease Diseases 0.000 description 1
- 230000007310 pathophysiology Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229960001813 ropivacaine hydrochloride Drugs 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000020341 sensory perception of pain Effects 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Adornments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9800139-9 | 1998-01-21 | ||
| SE9800139A SE9800139D0 (sv) | 1998-01-21 | 1998-01-21 | New use |
| PCT/SE1999/000012 WO1999037301A1 (en) | 1998-01-21 | 1999-01-11 | New use for pain management |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002501021A JP2002501021A (ja) | 2002-01-15 |
| JP2002501021A5 JP2002501021A5 (https=) | 2006-03-02 |
| JP4456754B2 true JP4456754B2 (ja) | 2010-04-28 |
Family
ID=20409917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000528283A Expired - Lifetime JP4456754B2 (ja) | 1998-01-21 | 1999-01-11 | 疼痛管理のための新規な使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6395291B1 (https=) |
| EP (1) | EP1054671B1 (https=) |
| JP (1) | JP4456754B2 (https=) |
| AT (1) | ATE228840T1 (https=) |
| AU (1) | AU2444399A (https=) |
| DE (1) | DE69904297T2 (https=) |
| DK (1) | DK1054671T3 (https=) |
| ES (1) | ES2189386T3 (https=) |
| PT (1) | PT1054671E (https=) |
| SE (1) | SE9800139D0 (https=) |
| WO (1) | WO1999037301A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200611217A (en) * | 2005-12-06 | 2006-04-01 | Shin Hwa Biotech Co Ltd | Human model for indexing nerve paths (locus) having corresponding relations and method for indexing |
| US8920843B2 (en) * | 2007-11-07 | 2014-12-30 | Svip5 Llc | Slow release of organic salts of local anesthetics for pain relief |
| US10111850B2 (en) * | 2015-12-01 | 2018-10-30 | Samuel Wilson | Ester and cholinesterase inhibitor in long-acting nerve block |
| CA2898933A1 (en) * | 2014-07-30 | 2016-01-30 | Grigory Karmy | Method for relieving chronic pain |
| US10751249B2 (en) * | 2017-11-26 | 2020-08-25 | Johnson Athletic Advantage LLC | Trigger point dry needling in motion and method of use |
| BE1026845B1 (nl) | 2018-12-07 | 2020-07-08 | Fagron Compounding Services Nv | Samenstelling voor gebruik in lokale infiltratie analgesie (LIA) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0151110B1 (en) | 1983-08-01 | 1989-03-01 | Astra Läkemedel Aktiebolag | L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same |
| SE451840B (sv) | 1986-01-03 | 1987-11-02 | Astra Laekemedel Ab | Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning |
| SE9401174D0 (sv) | 1994-04-07 | 1994-04-07 | Astra Ab | New combination |
| ATE219674T1 (de) | 1997-03-13 | 2002-07-15 | James N Campbell | Zusammensetzung enthaltend capsaicin oder seine analogen und lokalanästhetika |
-
1998
- 1998-01-21 SE SE9800139A patent/SE9800139D0/xx unknown
-
1999
- 1999-01-11 US US09/254,382 patent/US6395291B1/en not_active Expired - Lifetime
- 1999-01-11 ES ES99903972T patent/ES2189386T3/es not_active Expired - Lifetime
- 1999-01-11 DE DE69904297T patent/DE69904297T2/de not_active Expired - Lifetime
- 1999-01-11 JP JP2000528283A patent/JP4456754B2/ja not_active Expired - Lifetime
- 1999-01-11 AU AU24443/99A patent/AU2444399A/en not_active Abandoned
- 1999-01-11 PT PT99903972T patent/PT1054671E/pt unknown
- 1999-01-11 EP EP99903972A patent/EP1054671B1/en not_active Expired - Lifetime
- 1999-01-11 DK DK99903972T patent/DK1054671T3/da active
- 1999-01-11 AT AT99903972T patent/ATE228840T1/de active
- 1999-01-11 WO PCT/SE1999/000012 patent/WO1999037301A1/en not_active Ceased
-
2002
- 2002-04-24 US US10/128,664 patent/US6620423B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1054671B1 (en) | 2002-12-04 |
| DK1054671T3 (da) | 2003-02-24 |
| WO1999037301A1 (en) | 1999-07-29 |
| ATE228840T1 (de) | 2002-12-15 |
| US6395291B1 (en) | 2002-05-28 |
| PT1054671E (pt) | 2003-03-31 |
| US6620423B2 (en) | 2003-09-16 |
| EP1054671A1 (en) | 2000-11-29 |
| US20020156101A1 (en) | 2002-10-24 |
| DE69904297T2 (de) | 2003-08-21 |
| SE9800139D0 (sv) | 1998-01-21 |
| AU2444399A (en) | 1999-08-09 |
| JP2002501021A (ja) | 2002-01-15 |
| ES2189386T3 (es) | 2003-07-01 |
| DE69904297D1 (de) | 2003-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Grushka et al. | Burning mouth syndrome | |
| Moore et al. | The anesthetic efficacy of 4 percent articaine 1: 200,000 epinephrine: two controlled clinical trials | |
| Poellmann et al. | Current management of pain associated with multiple sclerosis | |
| Hersh et al. | The pharmacokinetics and cardiovascular effects of high-dose articaine with 1: 100,000 and 1: 200,000 epinephrine | |
| Gawin et al. | Outpatient treatment of'crack'cocaine smoking with flupenthixol decanoate: a preliminary report | |
| Majid | Submucosal dexamethasone injection improves quality of life measures after third molar surgery: a comparative study | |
| Othman et al. | Non‐opioid drugs for pain management in labour | |
| Baad-Hansen et al. | Differential effect of intravenous S-ketamine and fentanyl on atypical odontalgia and capsaicin-evoked pain | |
| Ernberg et al. | Ropivacaine for dental anesthesia: a dose-finding study | |
| Giannakopoulos et al. | The cardiovascular effects and pharmacokinetics of intranasal tetracaine plus oxymetazoline: preliminary findings | |
| Platon et al. | Effects of high-frequency, high-intensity transcutaneous electrical nerve stimulation versus intravenous opioids for pain relief after gynecologic laparoscopic surgery: a randomized controlled study | |
| JP4456754B2 (ja) | 疼痛管理のための新規な使用 | |
| KR20170120708A (ko) | 탈수초를 갖는 환자에서 4-아미노피리딘을 사용한 지속적 치료 | |
| Gupta et al. | Comparative evaluation of efficacy of EMLA and needleless jet anesthesia in non-surgical periodontal therapy | |
| Conforti et al. | Intradermal therapy (mesotherapy) for the treatment of acute pain in carpal tunnel syndrome: a preliminary study. | |
| Scott et al. | The efficacy of a repeated infiltration in prolonging duration of pulpal anesthesia in maxillary lateral incisors | |
| Gupta et al. | A comparative study of trigger point therapy with local anaesthetic (0.5% bupivacaine) versus combined trigger point injection therapy and levosulpiride in the management of myofascial pain syndrome in the orofacial region | |
| Vaiman et al. | Oxycodone and dexamethasone for pain management after tonsillectomy: a placebo-controlled EMG assessed clinical trial | |
| Hosny et al. | Anesthetic efficacy of 4% artpharmadent versus 2% mepecaine-l for infiltration anesthesia in extraction of badly decayed lower first primary molars: a pilot study | |
| Sabatke et al. | Trigger point infiltrations into the temporal muscles of patients with fibromyalgia and headaches: a randomized, double-blinded and controlled study | |
| Khidr et al. | Tempro Mandibular Joint Internal Derangement: A Comparative Analysis of Ozone Gas and Ozonated Water Following Arthrocentesis | |
| Joshi et al. | Comparative evaluation of pricking pain response, behavioural response, heart rate and blood pressure response to prilido cream and lignocad gel prior to local anesthesia administration in children | |
| SINGH et al. | Efficacy of Magnesium Sulfate and Dexmedetomidine as Adjuvants to Ropivacaine in Supraclavicular Brachial Plexus Block: A Randomised Clinical Study. | |
| Debnath et al. | Efficacy of Ultrasound-guided Autologous Blood Injection in Chronic Lateral Epicondylitis: A Randomized Controlled Trial | |
| Habaka et al. | Comparative study between Sodium hyaluronic acid and dextrose prolotherapy in management of Temporo-mandibular joint internal derangement. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060106 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060106 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090915 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20091211 |
|
| RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7422 Effective date: 20091211 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100126 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20100208 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130212 Year of fee payment: 3 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130212 Year of fee payment: 3 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140212 Year of fee payment: 4 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |