JP4413012B2 - ウイルスの製造方法 - Google Patents

ウイルスの製造方法 Download PDF

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Publication number
JP4413012B2
JP4413012B2 JP2003582315A JP2003582315A JP4413012B2 JP 4413012 B2 JP4413012 B2 JP 4413012B2 JP 2003582315 A JP2003582315 A JP 2003582315A JP 2003582315 A JP2003582315 A JP 2003582315A JP 4413012 B2 JP4413012 B2 JP 4413012B2
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JP
Japan
Prior art keywords
virus
temperature
cell
cells
culture
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Expired - Fee Related
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JP2003582315A
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English (en)
Japanese (ja)
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JP2005521423A (ja
JP2005521423A5 (enExample
Inventor
シエ，リアンツイー
グーチー，チヤールズ・エフ
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Merck and Co Inc
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Merck and Co Inc
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Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JP2005521423A publication Critical patent/JP2005521423A/ja
Publication of JP2005521423A5 publication Critical patent/JP2005521423A5/ja
Application granted granted Critical
Publication of JP4413012B2 publication Critical patent/JP4413012B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2003582315A 2002-03-29 2003-03-27 ウイルスの製造方法 Expired - Fee Related JP4413012B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36865402P 2002-03-29 2002-03-29
PCT/US2003/009269 WO2003085138A1 (en) 2002-03-29 2003-03-27 Methods of virus production

Publications (3)

Publication Number Publication Date
JP2005521423A JP2005521423A (ja) 2005-07-21
JP2005521423A5 JP2005521423A5 (enExample) 2006-05-11
JP4413012B2 true JP4413012B2 (ja) 2010-02-10

Family

ID=28791896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003582315A Expired - Fee Related JP4413012B2 (ja) 2002-03-29 2003-03-27 ウイルスの製造方法

Country Status (9)

Country Link
US (1) US7344873B2 (enExample)
EP (1) EP1492891B1 (enExample)
JP (1) JP4413012B2 (enExample)
AT (1) ATE386824T1 (enExample)
AU (1) AU2003226012B2 (enExample)
CA (1) CA2478901A1 (enExample)
DE (1) DE60319210T2 (enExample)
ES (1) ES2299715T3 (enExample)
WO (1) WO2003085138A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8426124B2 (en) * 2007-05-04 2013-04-23 Baxter International Inc. Two-step temperature profile for the propagation of viruses
WO2011130119A2 (en) 2010-04-14 2011-10-20 Millipore Corporation Methods of producing high titer, high purity virus stocks and methods of use thereof
US20110262965A1 (en) 2010-04-23 2011-10-27 Life Technologies Corporation Cell culture medium comprising small peptides
US9879229B2 (en) 2011-03-14 2018-01-30 National Research Council Of Canada Method of viral production in cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962424A (en) * 1974-01-31 1976-06-08 Recherche Et Industrie Therapeutiques (R.I.T.) Live brovine adenovirus vaccines, preparation thereof and method of vaccination using them
US5618714A (en) 1993-12-15 1997-04-08 Eli Lilly And Company Methods for producing protein C
US5837520A (en) * 1995-03-07 1998-11-17 Canji, Inc. Method of purification of viral vectors
DE69638058D1 (de) * 1995-06-15 2009-11-26 Crucell Holland Bv Verpackungssysteme für humane rekombinante Adenoviren zur Gentherapie
CA2378539A1 (en) 1999-07-06 2001-01-11 Merck & Co., Inc. Adenovirus carrying gag gene hiv vaccine
CA2422882A1 (en) 2000-09-15 2002-03-21 Merck & Co., Inc. Enhanced first generation adenovirus vaccines expressing codon optimized hiv1-gag, pol, nef and modifications

Also Published As

Publication number Publication date
US7344873B2 (en) 2008-03-18
US20050176146A1 (en) 2005-08-11
EP1492891B1 (en) 2008-02-20
AU2003226012A1 (en) 2003-10-20
DE60319210T2 (de) 2009-02-12
ES2299715T3 (es) 2008-06-01
EP1492891A4 (en) 2005-08-24
EP1492891A1 (en) 2005-01-05
JP2005521423A (ja) 2005-07-21
CA2478901A1 (en) 2003-10-16
WO2003085138A1 (en) 2003-10-16
AU2003226012B2 (en) 2007-05-24
ATE386824T1 (de) 2008-03-15
DE60319210D1 (de) 2008-04-03

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