JP4358590B2 - Manufacturing method of medical guide wire - Google Patents

Description

  The present invention relates to a method for manufacturing a medical guide wire. More specifically, the present invention relates to a guide wire used for guiding a catheter, in which a curved portion having a desired shape is provided at a distal end.

JP-A-4-108456 Japanese Patent No. 3300155

  A guide wire is inserted prior to the catheter to guide the catheter to a target site within the blood vessel. The tip portion is mainly formed in a J shape or a loop shape so that it can smoothly enter a blood vessel having a severe curvature. Such a tip has a core wire formed so as to become gradually thinner toward the tip, and a coil attached to the entire outer periphery of the core wire or only the outer periphery of the curved tip. The core wire of the guide wire is strong enough to be operated at hand, and the outer peripheral coil is flexible so as not to damage the blood vessel wall.

  A conventional example of such a guide wire is shown in FIG. The guide wire 100 includes a core wire 101 made of stainless steel, carbon steel, or Ni—Ti wire, and a coil 102 made of stainless steel, platinum, platinum alloy, or tungsten, and has a flexible curved portion 100a at one end thereof. .

  In Patent Document 1, as shown in FIG. 12a, the tip 101a of the core wire 101 is bent into a J shape in advance, and the corresponding portion 102a of the coil (spring body) 102 is also bent into a J shape. Thereafter, a manufacturing method combining both is described as a prior art (the upper left column of page 2 of the publication). Further, as shown in FIG. 12b, a method of manufacturing by bending only the core wire 101 into a J shape in advance and combining it with the straight coil 102 is also described.

  In Patent Document 1, it is difficult to accurately match the curved shapes of the core wire 101 and the coil 102 with the former manufacturing method, and the manufacturing process is complicated. With the latter manufacturing method, a guide wire with an accurate curved shape is obtained. However, it is proposed that the number of turns of the coil 102 be formed so as to be sparse at a portion corresponding to the curved portion 101a of the core wire 101, basically following the latter manufacturing method. According to this manufacturing method, the elastic deformation of the J-shaped portion 101a of the core wire due to the elasticity of the coil 102 can be suppressed. In addition, as a material of the core wire 101 and the coil 102, the super elastic metal of Ni-Ti alloy other than stainless steel is mention | raise | lifted.

  On the other hand, in Patent Document 2, as shown in FIG. 13, a straight core wire 101 and a coil 102 are combined in advance, and then the combined 103 is inserted into a mold 105 having a J-shaped groove 104. A manufacturing method is disclosed in which a curved shape is formed by performing a heat treatment after the lid 106 is attached. In this manufacturing method, the material of the core wire 101 is stainless steel or steel, and the coil 102 is stainless steel, platinum, a platinum alloy, gold, or tungsten.

  In the manufacturing method of Patent Document 1, the core wire 101, which is a metal wire, is bent into a J shape. For this reason, in order to bend accurately into a predetermined curved shape, it is necessary to form an extra curved shape and return the spring back to the predetermined shape. Furthermore, when the straight coil 102 is mounted, some elastic deformation due to it needs to be calculated. In addition, when a metal wire is bent, internal stress remains and may deform from the original shape after a long period of time.

  The manufacturing method of Patent Document 2 has an advantage that there is almost no springback because the core wire 101 and the coil 102 are combined and inserted into the mold 105 to maintain a predetermined curved shape and heat treatment. Moreover, the internal stress is also reduced by the heat treatment. However, in this manufacturing method, since the whole including the mold is heated, the time required for heating and the time required for cooling the whole tend to be long.

  Furthermore, in this manufacturing method, it is necessary to use a material having a high melting temperature as a brazing material used when the core wire 101 and the coil 102 are combined. Therefore, the brazing operation becomes complicated. That is, in a general guide wire, when the core wire 101 and the coil 102 are combined, the end portion of the coil 102 is brazed to the core wire 101 and integrated. In that case, a soft brazing material such as solder that melts at a low temperature is preferable, but since it reaches 400 to 600 ° C. during heat treatment, such a material cannot be used. For example, a brazing brazing material having a melting temperature of 600 ° C. or more is used. Need to use. Therefore, the brazing work is complicated.

  An object of the present invention is to provide a guide wire manufacturing method that can accurately match a curved shape to a design shape as much as possible and can reduce the time required for manufacturing. Furthermore, it is a technical object of the present invention to provide a manufacturing method in which a curved shape can be adjusted to a design shape as accurately as possible, and a brazing material can be selected as freely as possible.

A first aspect of the medical guide wire manufacturing method of the present invention (Claim 1) is a method for manufacturing a medical guide wire comprising a core wire and a coil attached to the outer periphery thereof, and the core wire and the coil are desired. insert each a metal cylindrical mold thin curved in shape, no rows each heat treatment for them are placed in cylindrical molds each furnace shaping, after which the coil on the outer periphery of the core wire It is characterized by wearing.
In addition, the guide wire manufacturing method is preferably such that the core wire and the coil mold are each curved in a spiral shape of one or more turns.

A second aspect of the production method of the present invention (Claim 3 ) is a method for producing a medical guide wire comprising a core wire and a coil attached to the outer periphery thereof, and the coil is attached to the outer periphery of the core wire. They are characterized in that they are inserted into a metal thin cylindrical mold bent into a desired shape, and the core wire and coil are placed in a furnace together with the cylindrical mold to perform heat treatment for shaping . .

A third aspect (Claim 4 ) of the manufacturing method of the present invention is a method for manufacturing a medical guide wire comprising a core wire and a coil attached to the outer periphery thereof, wherein the core wire is bent into a desired shape. insert Made in a cylindrical mold thin, the core wire subjected to heat treatment for shaping placed in a mold your capital furnace, providing a coil in advance of the plurality duty length, desired that coil In a state where the metal rod-shaped die having an outer diameter of 5 mm is spirally wound around the outer periphery of the metal rod, it is placed in a furnace and subjected to heat treatment for shaping, and then the spirally shaped coil is equivalent to one guide wire. It is characterized by a method for manufacturing a medical guide wire in which a coil is attached to the outer periphery of a core wire after cutting .

A fifth aspect of the manufacturing method of the present invention (Claim 5) is a method for manufacturing a medical guide wire comprising a core wire, a coil attached to the outer periphery thereof, and a flat plate member disposed inside the coil. A first step of inserting the flat strip member into the coil and fixing one end thereof to one end of the coil, and a metal made of a metal previously curved into a desired shape in the coil obtained in the first step . a second step of inserting a thin cylindrical mold insert and core wire subjected form I line heat treatment, the other end of the coil obtained in the second step was adjusted position relative to the core wire It is characterized by comprising a third step of folding back and a core wire in the vicinity of the folded back and fixing the coil .
Further, in any of the above manufacturing methods, such an apparatus is preferably a heat treatment comprising a heating step performed at 80 to 700 ° C. for 3 to 200 minutes and a subsequent heat dissipation step (Claim 6).

In the first aspect (Claim 1) of the method for producing a medical guide wire according to the present invention, the core wire and the coil are separately heat-treated, so that the temperature setting and heating time can be further adjusted according to each material and shape. Can be set finely. Further, since the coil is mounted around the core wire after the heat treatment, a soft solder material having a low melting point such as solder can be employed. Therefore, the brazing operation is easy and there is no damage due to the heat effect on the base material. Further, since the heat treatment is performed by inserting into a cylindrical mold, the entire heating time and cooling time can be shortened, and the time required for production can be shortened.
Further, in such a guide wire manufacturing method, when the core wire and the coil mold are each curved in a spiral shape having one or more turns (Claim 2), the guide wire tip portion is made one or more turns. A curved shape can be obtained.

In the second aspect of the manufacturing method of the present invention (Claim 3 ), since the one with the coil attached to the outer periphery of the core wire is inserted into a cylindrical mold and heat treatment is performed, the heating time and the cooling time are shortened, The time required for manufacturing can be shortened. Even when a coil is attached around the core wire in advance and the end of the coil is brazed to the core wire, the brazed portion is near the end of the cylindrical mold, so the heating temperature of that portion is lowered. So that a brazing material having a relatively low melting temperature can be used.

In the third aspect of the manufacturing method of the present invention (Claim 4 ), the core wire and the coil are separately heat-treated, and then the coil is mounted on the outer periphery of the core wire, so a low melting point brazing material such as solder is used. And brazing is easy. Moreover, since the coil is exposed to the outside of the mold, the heat treatment time can be greatly shortened. Furthermore, since a plurality of coils can be wound around the outer periphery of the rod-shaped mold, the plurality of coils can be simultaneously heat-treated with one mold. Moreover, when it winds around the outer periphery of a rod-shaped type | mold and heat-processes and cut | disconnects one piece after that, the coil by which heat processing was performed efficiently can be obtained.

According to a fifth aspect (Claim 5) of the manufacturing method of the present invention, there is provided a method for manufacturing a medical guide wire comprising a core wire, a coil attached to the outer periphery thereof, and a flat belt member disposed inside the coil. A first step of inserting the flat strip member into the coil and fixing one end thereof to one end of the coil, and a metal made of a metal previously curved into a desired shape in the coil obtained in the first step . a second step of inserting a thin cylindrical mold insert and core wire subjected form I line heat treatment, the other end of the coil obtained in the second step was adjusted position relative to the core wire Later, it consists of the third step of fixing the coil and the core wire in the vicinity of the folded back, so that the coil is positioned and fixed to the core wire whose springback has been reduced by heat treatment and the outer periphery of the core wire. High dimensional accuracy.
Moreover, in the said manufacturing method, when heat processing consists of the heating process performed for 3 to 200 minutes at 80-700 degreeC, and the subsequent heat dissipation process (Claim 6), the operation | work of the oxide film removal of a core wire or a coil after heat processing Becomes easier.

Next, an embodiment of a method for producing a medical guide wire according to the present invention will be described with reference to the drawings. FIG. 1 is a flowchart showing an embodiment of the manufacturing method of the present invention, FIG. 2 is a process diagram showing in detail the heat treatment process of the core wire in the manufacturing method of FIG. 1, and FIG. 3 shows the coil heat treatment process in detail in the manufacturing method of FIG. FIG. 4 is a process diagram showing another embodiment of the heat treatment process of the core wire and coil shown in FIG. 5 and 6 are partial process drawing showing another embodiment of the manufacturing method of the present invention, FIG. 7 is a process diagram showing an embodiment related to the second state like the production method of the present invention, FIG 8 is the invention FIG . 9 and FIG. 10 are process diagrams showing embodiments relating to the fifth aspect and the fifth aspect of the manufacturing method of the present invention, respectively.

  The manufacturing method shown in FIG. 1 includes a step S1 for manufacturing a coil, a step S2A or S2B for mounting the coil on a mold, a step S3 for heat-treating the coil for each mold, and a step for manufacturing a core wire separately from the coil. S4, step S5 for inserting the core wire into a cylindrical mold, step S6 for heat treating the core wire together with the cylindrical mold, step S7 for removing the oxide film of the heat treated core wire, and the obtained coil Step S8 for assembling the core wire, Step S9 for brazing the end of the coil to the core wire, Step S10 for polishing the obtained guide wire, and Step S11 for cleaning. In the step of attaching the coil to the mold, the coil may be wound around a rod (step S2A) or may be inserted into a cylindrical mold (step S2B).

  FIG. 2 illustrates the details. First, the manufacturing process of the left core wire 11 in FIG. 2 will be described. For the core wire 11, first, a metal wire such as stainless steel or steel wire having a diameter of about 0.3 to 1.0 mm is cut into a predetermined dimension within 3000 mm, and a portion to be curved is preliminarily thinned (hereinafter referred to as “this”). The portion is referred to as a thin portion 12), the tip portion 13 is formed into a taper shape, the end portion is polished, and the like is formed into a predetermined shape and accuracy (S 4). This partially thinning process is performed by a known method such as drawing with a die. In addition to the above, Ni—Ti wire or the like can also be used as the core wire material.

  Next, the thin portion 12 of the obtained core wire 11 is inserted into a thin metal curved cylindrical mold 14 (S5). However, it may be wound around the outer surface of a cylindrical rod (not shown). In FIG. 2, the thin portion of the core wire 11 has a substantially J-shape and the number of turns does not reach one turn, but may be one and a half turns or more. In that case, it molds using a spiral cylindrical metal mold | die (FIG. 4). When the thin portion 12 of the core wire 11 is wound around the outer surface of the rod, it is easy to mold one or more turns. The cylindrical metal mold 14 or rod is preferably made of a metal having high thermal conductivity and easy to form, and for example, stainless steel or copper alloy can be used. The inner diameter of the cylindrical mold 14 is preferably 3.0 mm or less in consideration of heating and cooling (heat radiation) in a short time. The curved shape of the cylindrical mold 14 is made to match the shape of the core wire 11 after shaping. Or, considering the restoration after shaping, the shape is made slightly smaller. Since the thin portion 12 of the core wire 11 has elasticity, it is relatively easy to insert it into the curved cylindrical mold 14.

Next, the core wire 11 together with the cylindrical mold 14 is placed in a furnace, and heat treatment is performed in the air or in an inert gas atmosphere (S6). Nitrogen as an inert gas, helium, argon, and the like an argon mixed gas is used, argon is preferred. The temperature and time of the heat treatment are preferably about 80 to 700 ° C. and about 3 to 200 minutes.

  After heat radiation, the core wire 11 is extracted from the cylindrical mold 14 (step S6a in FIG. 2). Thereby, the thin portion 12 of the core wire 11 is formed into a curved shape. In this state, the internal stress is almost removed, the shape is maintained even after a long period of time, and the original shape is restored even when elastically deformed. Further, the oxide film of the obtained core wire 11 having a predetermined curved shape is removed (S7).

  Next, the manufacturing process of the coil 16 will be described with reference to FIG. 3 (S1). A metal wire such as a spring steel wire such as stainless steel having a diameter of 0.05 to 0.5 mm is used for the coil 16. As the material for the coil, platinum, platinum alloy, gold, tungsten, or alloys thereof having non-translucency with respect to X-rays can be used in addition to the above.

  The coil 16 is then wound around the outer surface of a cylindrical rod 19 (S2A) or inserted into a thin metal curved cylindrical mold 17 (S2B). When winding around the outer surface of the rod 19, a plurality of coils 16 may be wound and heat treated at once (S3A), and a plurality of lengths of the coil 16 may be wound several times, It can also be processed at once (not shown). Similar to the case of the core wire 11, those made of stainless steel or copper alloy can also be used for the rod body 19 and the cylindrical mold 17. The curved shape of the rod 19 and the cylindrical mold 17 is made to be a shape that matches the shape after the coil 16 is shaped, or is made slightly smaller in consideration of restoration after the shaping. Since the coil 16 has elasticity, it can be easily wound around the outer surface of the curved bar 19 or inserted into the cylindrical mold 17. In FIG. 3, the coil 16 has a substantially J-shape and the number of turns does not reach one, but as shown in FIG. 4, the number of turns is one and a half or more like the core wire 11. You can also. In that case, it molds using a spiral cylindrical metal mold | die.

  Next, as in the case of the core wire 11, the coil 16 together with the rod 19 or the cylindrical mold 17 is placed in a furnace and heat treatment is performed in the atmosphere or in an inert gas atmosphere (S 3). The temperature and time of the heat treatment of the coil 16 are preferably 80 to 700 ° C. and about 3 to 200 minutes. After the heat radiation, the coil 16 is removed from the rod 19 or the cylindrical mold 17. When the coil 16 having several lengths is wound around the rod 19, the coil 16 is taken out and cut into lengths one by one. Thereby, the curved coil 16 is obtained (step S3a in FIG. 3).

  Next, as shown in step S8 of FIG. 2, the coil 16 is attached to the core wire 11 in which the thin portion 12 is curved. Soft solder such as solder is used for the brazing material. Thereby, the guide wire 10 in which the coil 16 is attached to the core wire 11 is obtained.

  Thereafter, as shown in FIG. 1, the guide wire 10 is completed by polishing the soldered end portion and the tip (step S <b> 10) and washing (step S <b> 11). After that, the dimensions are inspected and packed.

  According to the above manufacturing method, the core wire 11 and the coil 16 are inserted into the thin metal cylindrical dies 14 and 17 or wound around the rod body 19 and heat-treated while maintaining the shape. This heat is easily conducted to the core wire 11 and the coil 16 and rises to a temperature required for heat treatment in a short time. Moreover, heat radiation can be performed in a short time. Therefore, the time required for manufacturing can be shortened. Furthermore, since the core wire 11 and the coil 16 are formed separately, and then both are combined and brazed, a low melting point brazing material such as solder can be used, and the brazing operation is easy. Further, since heat treatment is performed in an inert gas atmosphere, the generation of an oxide film is small.

  In the embodiment, after the heat treatment of the coil 16, the coil 16 is extracted from the cylindrical mold 17 and then attached to the core wire 11. However, as shown in FIG. 3, the coil 16 is not extracted from the cylindrical mold 17. The core wire 11 may be inserted into the coil 16 (step S6b in FIG. 5). In that case, since the coil 16 can be handled as a rigid body, the core wire 11 can be inserted more easily. Then, after the core wire 11 is inserted, the core wire 11 is pulled out and then brazed, or is brazed first and then pulled out.

  In the embodiment shown in FIG. 2, the coil 16 is inserted into the cylindrical mold 17 and heat-treated. However, as shown in FIG. 6, a curved rod 18 is inserted into the center of the coil 16, and in this state. You may make it heat-process. The rod body 18 has heat resistance and rigidity. According to this method, when the rod 18 is extracted from the coil 16, the tip of the core wire 11 can be sequentially inserted after the rod 18 is pulled out, and the insertion into the core 11 is facilitated.

  The manufacturing method shown in FIG. 7 is the same as the manufacturing method of FIG. 2 in that a cylindrical mold is used as a shaping die, but the core wire 11 and the coil 16 remain straight (steps S1 and S4). In the combination (step S12), both are inserted into the cylindrical mold 21 and heat treatment is performed (S13). After the heat treatment, the coil 16 is extracted from the cylindrical mold 21, and the coil 16 is once extracted from the core wire 11 (step S14). Thereafter, as in the latter half of the step of FIG. 1, the oxide film on the core wire 11 is removed (step S7 of FIG. 1), reassembled (step S8), brazed (step S9), polished (step S10), and Cleaning (step S11) is performed.

  In this manufacturing method, only one common cylindrical mold 21 needs to be prepared, and heat treatment is performed together, so that the heat treatment process is simplified. However, the manufacturing process is complicated in that the coil once assembled is removed after the heat treatment. About the quality of a product, since the core wire 11 elastically deforms inside the coil 16, accuracy is inferior compared with the case of FIG. On the other hand, it is the same as the manufacturing method of FIG. 2 in that the oxide film is removed and brazing with a low melting point soft solder such as solder, and the same quality can be maintained.

  It is also possible to perform brazing when assembled (step S12), and simply perform final polishing and cleaning after the heat treatment. In that case, a brazing filler metal having a melting point higher than the heat treatment temperature is used. Therefore, brazing work becomes complicated. Further, the process of removing the oxide film from the core wire after the heat treatment cannot be performed by a normal method because of the presence of the brazing material, and thus a complicated process is required. Moreover, the brazing material may be significantly affected by this complicated process, leading to strength deterioration.

Although outside the scope of the present invention, the manufacturing method shown in FIG. 8 includes a mold 24 having a concave groove 23 similar to that in Patent Document 2 in a shaping mold, and a lid 25 that covers the mold. Except for use, it is the same as the manufacturing method of FIG. This manufacturing method increases the time required for heating and the time required for heat dissipation during heat treatment. However, when brazing the coil 16 to the core wire 11, a low melting point soft solder material such as solder can be used, and the oxide film of the core wire 11 after heat treatment can be easily removed. Almost the same operational effects can be achieved.

  In any of the above-described embodiments, the thin portion 12 is formed near the tip of the core wire 11 and the coil 16 is mounted on the outer periphery of the thin portion 12. However, the coil is mounted over the entire length of the core wire 11. You can also. Further, a thin portion and a coil are provided at one end of the core wire 11 to provide a bending portion, and a similar bending portion having a thin portion and a coil can also be provided at the other end. In that case, it is preferable that the curvature of the curve is changed, the length is not changed, or the central angle is changed so that the user can select which curved portion to insert into the human body. The other end may be kept straight by only providing a thin portion and a coil.

  FIG. 9 is a diagram showing an embodiment relating to the fifth aspect of the present invention. This embodiment is called a stylet that is used simultaneously or separately with a guide wire. The stylet 28 includes a core wire 11 and a coil 16 having a central portion inserted into the outer periphery of the core wire 11. The core wire 11 includes a J-shaped portion 29 at the front end, a folded back portion 30 at the rear end portion, and a main body 31 that is a portion between the two. The end of the J-shaped portion 29 of the stylet 28 configured in this way is fixed at one end by a spherical portion 33 and the spherical portion 33, and is disposed on the inner side of the curve on the inner surface of the coil 16. A flat strip member 26 is provided. The spherical portion 33 fixes the coil 16 and the flat strip member 26. On the other hand, the portion of the other folded portion 30 of the stylet 28 fixed so as to face each other is a handle portion 27. The entire outer surface of the handle portion 27 is covered with a tube 32.

  Next, each member will be described in detail. Moreover, the description of the same part as the above-described embodiment is omitted. The core wire 11 has a diameter of 0.3 to 1.0 mm, and a metal wire such as a spring steel wire such as stainless steel is used. The same wire as the other examples described above is used, and the total length is 500 to 1500 mm. is there. The coil 16 has a diameter of 0.5 to 1.5 mm, and a metal wire similar to that of the above-described embodiment such as a spring steel wire such as stainless steel is used. The overall length is 500 to 1500 mm, preferably about 1100 mm. .

  The flat strip member 26 is a rolled wire having a thickness of 0.02 to 0.5 mm and a width of 0.1 to 0.5 mm, and the material thereof is the same material as the coil, such as stainless steel. A low melting point soft solder material such as solder can be used to assemble the coil 16 and the flat strip member 26. However, if plasma welding or the like is performed, the heat concentration is good, so that the welding operation can be performed quickly, so that the distortion is reduced. The work can be held down, leading to improved dimensional accuracy. By the spherical portion 33 formed by welding as described above, the coil 16 and the flat plate-like member 26 having one end fixed to the tip portion of the coil 16 are welded. Further, since the flat belt-like member 26 can be bent relatively flexibly in the thickness direction, the coil 16 is also bendable in that direction and has rigidity in the axial direction. Therefore, the buckling strength in the axial direction can be increased for high flexibility, and the usability is good.

  The handle portion 27 is formed by welding portions facing each other folded back at the folded portion 30 with solder or the like. When the handle portion 27 is grasped by a hand, the stylet 28 can be easily operated. Also, a resin tube 32 is placed over the handle portion 27 fixed with solder, and has effects such as prevention of slipping and improvement of operation feeling when grasped by hand. The resin tube 32 is preferably made of a material such as vinyl chloride or urethane.

  FIG. 10 is a process diagram showing an embodiment according to the fifth aspect. This step includes a step S1 for producing a coil, a step S16 for producing a flat strip member separately, a step S17 for roughly cutting the flat strip member, and a roughly cut flat strip member inside the coil 16. Step S18 for insertion, Step S19 for plasma welding and welding them at the coil tip, and Step S4 for manufacturing the core wire, and the tip of the core wire is bent in a J shape, and the rear end is Step S15 for processing to be folded, Step S6 for heat treating the core wire, Step S7 for removing the oxide film, Step S8 for inserting the obtained core wire into the coil obtained in the tip plasma welding step S19, A step S20 for soldering the folded portion 30 and the main body 31, a step S21 for producing a tube separately from it, and covering the folded portion with the tube. Comprising the step 22 for the Chi hand portion.

  From here, each process is demonstrated in detail. In addition, portions that are the same as in the above-described embodiment are omitted. First, on the left side of FIG. 10, the flat strip member cut to a predetermined length in the rough cutting step S17 is inserted into the coil obtained in the coil manufacturing step S1 through the flat strip member manufacturing step S16. (Step S7), the tip portions are welded by plasma welding (Step S18). Further, on the right side of FIG. 10 in another process, a core wire is manufactured (process S4), and the core wire is bent by machining or the like so that the front end portion is J-shaped and the rear end portion is folded back (step S15). Then, heat treatment is performed (step S6). The heat treatment conditions at this time are substantially the same as the core wire of the above-described embodiment. After the heat treatment step of the heat treatment step S6, the oxide film removal step S7 for removing the oxide film is continued. This oxide film removal step is also the same as described above. If the dimensional accuracy is sufficiently high even after the heat treatment due to the material of the core wire and its dimensions, as in this embodiment, there is no need for a mold for heat treatment. In this case, the temperature rise for the heat treatment and the cooling time are shortened. In addition, since no mold is used, several treatments can be performed by a single heat treatment, and the heat treatment process time is greatly reduced.

  The core wire and coil thus obtained are assembled in the assembling step S8. At this time, it adjusts so that the front-end | tip part of a core wire may be drawn and arrange | positioned about 3-8 mm (FIG. 9d) from the front-end | tip part by which the coil 16 and the flat strip member 26 were welded. In this way, the portion of 3 to 8 mm from the tip is very flexible in the vertical direction of the flat strip member, and can be provided with appropriate rigidity in the axial direction, thus maintaining high flexibility. And become difficult to buckle. The position of the tip is adjusted when the coil 16 and the core wire 11 are assembled. And the folding | returning part 30 is soldered with this state. Further, the pitch of the coil of the solder portion (FIG. 9 e) may be opened so that the solder flows into the core wire 11 and the flat strip member 26 in the coil 16.

  Further, in the tube manufacturing step S21, a tube that covers the handle portion manufactured in the soldering step S20 is manufactured. Next, in the resin component insertion step S22, the obtained tube is attached to the handle portion, and the stylet 28 is completed. After that, the dimensions are inspected and packed. The stylet 28 manufactured by such a process can increase the dimensional accuracy of the flexible portion at the tip.

It is a flowchart which shows one Embodiment of the manufacturing method of this invention. It is process drawing which shows in detail the heat processing process of the core wire in the manufacturing method of FIG. It is process drawing which shows the heat processing process of the coil in the manufacturing method of FIG. 1 in detail. It is process drawing which shows the other Example of the heat processing process of the core wire and coil of FIG. It is a partial process figure which shows other embodiment of the manufacturing method of this invention. It is a partial process figure which shows other embodiment of the manufacturing method of this invention. It is process drawing which shows embodiment in connection with the 2nd aspect of the manufacturing method of this invention. Is a process drawing showing an example that involved the range of manufacturing how the present invention. It is a figure which shows embodiment concerning the 5th aspect of the manufacturing method of this invention. It is process drawing which shows embodiment in connection with the 5th aspect of the manufacturing method of this invention. It is a schematic front view which shows an example of the guide wire manufactured with the manufacturing method of this invention. 11a and 11b are process diagrams showing an example of a conventional manufacturing method. It is process drawing which shows the other example of the conventional manufacturing method.

Explanation of symbols

S1 Coil manufacturing process S2A Rod mounting process S2B Cylindrical mold insertion process S3 Heat treatment process S4 Core wire manufacturing process S5 Cylindrical mold insertion process S6 Heat treatment process S7 Oxide film removing process S8 Assembly process S9 Brazing process S10 Polishing step S11 Cleaning step S12 Combining step S13 Heat treatment step S14 Pulling out coil from core wire S15 Bending step S16 Flat strip member manufacturing step S17 Rough cutting step S18 Flat strip member inserting step S19 Tip plasma welding step S20 Soldering step S21 Tube step S22 Resin component insertion step d Tip length e Welding length 10 Guide wire 11 Core wire 12 Thin portion 13 Tip portion 14 Cylindrical die 16 Coil 17 Cylindrical die 18 Rod 19 Rod 21 Cylindrical die 23 concave groove 24 mold 25 lid 26 flat plate member 27 handle portion 28 Tairetto 29 J-shaped portion 30 folded portion 31 the body 32 tube 33 spherical portion 100 the guide wire 100a curved portion 101 core 101a tip 102 coils 102a J-type region 103 coils - core assembly 104 groove 105 mold 106 lid

Claims (6)

A method for producing a medical guide wire comprising a core wire and a coil attached to the outer periphery thereof,
The core wire and coil respectively inserted into the cylindrical mold of the curved metal thin to a desired shape,
No rows each heat-treated for shaping putting them into cylindrical molds each furnace,
Then, the manufacturing method of the medical guide wire which equips the outer periphery of a core wire with a coil. The method for manufacturing a medical guide wire according to claim 1, wherein the core wire and the coil mold are each curved in a spiral shape of one or more turns. A method for producing a medical guide wire comprising a core wire and a coil attached to the outer periphery thereof,
Attach the coil to the outer periphery of the core wire, then insert them into a metal thin cylindrical mold bent into the desired shape,
A method for producing a medical guide wire, wherein the core wire and the coil are placed in a furnace together with a cylindrical mold and heat treatment is performed for shaping . A method for producing a medical guide wire comprising a core wire and a coil attached to the outer periphery thereof,
Insert the core wire into a metal thin cylindrical mold bent into a desired shape ,
Subjected to heat treatment for shaping put the core in a mold your capital furnace,
Prepare multiple coils in advance,
The coil is put into a furnace in a state of being spirally wound around the outer periphery of a metal rod-shaped mold having a desired outer diameter, and heat treatment for shaping is performed,
Next, the spirally shaped coil is cut into one guide wire,
Then, the manufacturing method of the medical guide wire which equips the outer periphery of a core wire with a coil. A method for producing a medical guide wire comprising a core wire, a coil to be mounted on the outer periphery thereof, and a flat belt member disposed inside the coil,
A first step of inserting the flat strip member into a coil and fixing one end thereof to one end of the coil;
As in the first coil obtained in step, a second step of inserting a core wire attached form I to a heat treatment by inserting beforehand a desired metal cylindrical mold thin curved in shape line,
A method for manufacturing a medical guide wire comprising the third step of fixing the coil and the core wire in the vicinity of the folded back after the position of the other end of the coil obtained in the second step is adjusted with respect to the core wire. . A heating step in which the heat treatment is performed at 80 to 700 ° C. for 3 to 200 minutes;
The method for manufacturing a medical guide wire according to claim 1, further comprising a subsequent heat dissipation step.