JP4309839B2 - 金属メソポルフィリンハライド化合物の調製 - Google Patents

金属メソポルフィリンハライド化合物の調製 Download PDF

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Publication number
JP4309839B2
JP4309839B2 JP2004509690A JP2004509690A JP4309839B2 JP 4309839 B2 JP4309839 B2 JP 4309839B2 JP 2004509690 A JP2004509690 A JP 2004509690A JP 2004509690 A JP2004509690 A JP 2004509690A JP 4309839 B2 JP4309839 B2 JP 4309839B2
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Prior art keywords
mesoporphyrin
tin
dichloride
stannsoporphyrin
formate
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JP2004509690A
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Japanese (ja)
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JP2005528444A5 (enExample
JP2005528444A (ja
Inventor
ヴコヴィッチ，ロバート
レヴィンソン，ベンジャミン
カロセッリ，ロバート
ドラモンド，ジョージ
アンチャック，カジミエシュ
バウチャー，クリストファー
モーティマー，リチャード
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インファケア・ファーマシューティカル・コーポレイション
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Publication of JP2005528444A5 publication Critical patent/JP2005528444A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic Table without C-Metal linkages

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP2004509690A 2002-06-04 2003-06-03 金属メソポルフィリンハライド化合物の調製 Expired - Fee Related JP4309839B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38549802P 2002-06-04 2002-06-04
PCT/US2003/017426 WO2003101999A2 (en) 2002-06-04 2003-06-03 Preparation of metal mesoporphyrin halide compounds

Publications (3)

Publication Number Publication Date
JP2005528444A JP2005528444A (ja) 2005-09-22
JP2005528444A5 JP2005528444A5 (enExample) 2008-10-23
JP4309839B2 true JP4309839B2 (ja) 2009-08-05

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ID=29712178

Family Applications (1)

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JP2004509690A Expired - Fee Related JP4309839B2 (ja) 2002-06-04 2003-06-03 金属メソポルフィリンハライド化合物の調製

Country Status (10)

Country Link
US (1) US6818763B2 (enExample)
EP (2) EP1509527B1 (enExample)
JP (1) JP4309839B2 (enExample)
AU (2) AU2003237349B2 (enExample)
CA (1) CA2487426C (enExample)
MX (1) MXPA04012045A (enExample)
NO (1) NO333406B1 (enExample)
NZ (1) NZ536666A (enExample)
WO (1) WO2003101999A2 (enExample)
ZA (1) ZA200409670B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7375216B2 (en) * 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
US20040097481A1 (en) * 2002-11-20 2004-05-20 Benjamin Levinson Water-soluble mesoporphyrin compounds and methods of preparation
GB2397067B (en) 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture
AU2012202684B2 (en) * 2006-10-04 2014-04-10 Mallinckrodt Hospital Products IP Limited High-purity large-scale preparation of stannsoporfin
RS52185B (sr) * 2006-10-04 2012-10-31 Infacare Pharmaceutical Corporation Preparat stansoporfina sa visokim stepenom čistoće
CN101631554A (zh) * 2006-10-04 2010-01-20 婴儿护理药品公司 使用低剂量锡泊芬治疗婴儿高胆红素血症
WO2011160102A2 (en) 2010-06-19 2011-12-22 Perimetrics, Llc System and method for determining structural characteristics of an object
WO2012135686A1 (en) 2011-03-30 2012-10-04 Infacare Pharmaceutical Corporation Methods for synthesizing metal mesoporphyrins
US9869606B2 (en) 2011-06-18 2018-01-16 Perimetrics, Llc System and method for determining structural characteristics of an object
WO2013082559A1 (en) 2011-12-01 2013-06-06 Infacare Pharmaceutical Corporation Methods for treating hyperbilirubinemia with stannsoporfin
AU2015324103C1 (en) 2014-09-29 2020-08-20 Fred Hutchinson Cancer Center Compositions, kits, and methods to induce acquired cytoresistance using stress protein inducers
CN110139625A (zh) * 2016-12-30 2019-08-16 佩里梅特里克斯有限责任公司 用于确定对象的结构特性的系统和方法

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US4684637A (en) 1981-07-15 1987-08-04 The Rockefeller University Method of decreasing rate of heme metabolism
US4657902A (en) 1985-03-25 1987-04-14 The Rockefeller University Therapeutic use of tin mesoporphyrin
US4692440A (en) 1985-03-25 1987-09-08 The Rockefeller University Therapeutic use of tin mesoporphyrin
JPS61250643A (ja) 1985-04-30 1986-11-07 Konishiroku Photo Ind Co Ltd ハロゲン化銀写真感光材料
US4861876A (en) 1986-11-26 1989-08-29 Wayne State University Hematoporphyrin derivative and method of preparation and purification
US4782049A (en) 1986-12-08 1988-11-01 The Rockefeller University Tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis
US4900871A (en) 1987-01-02 1990-02-13 Sun Refining And Marketing Company Hydrocarbon oxidations catalyzed by iron coordination complexes containing a halogenated ligand
US5990363A (en) 1987-01-02 1999-11-23 Sun Company, Inc. Method for oxidizing alkanes using novel porphyrins synthesized from dipyrromethanes and aldehydes
US5192757A (en) 1990-12-20 1993-03-09 Glaxo Inc. Cobalt porphyrins
US5817830A (en) 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
US5371199B1 (en) 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5493017A (en) 1992-08-14 1996-02-20 The Trustees Of The University Of Pennsylvania Ring-metalated porphyrins
CA2130853A1 (en) 1994-08-25 1996-02-26 Svetlana Kudrevich Process for the syntheses of monosulphonated phthalocyanines, naphthobenzoporphyrazines and porphyrins via a modified meerwein reaction
WO1997005152A1 (en) 1995-08-02 1997-02-13 Warner-Lambert Company Amino acid complexes of cobalt (iii) mesoporphyrin ix and cobalt (iii) protoporphyrin ix
US5883246A (en) 1996-03-07 1999-03-16 Qlt Phototherapeutics, Inc. Synthesis of polypyrrolic macrocycles from meso-substituted tripyrrane compounds
US6004530A (en) 1996-06-04 1999-12-21 Roche Diagnostics Gmbh Use of metallo-porphyrin conjugates for the detection of biological substances
GB9616353D0 (en) 1996-08-03 1996-09-11 Secr Defence Metallo-porphyrins
US6124452A (en) 1997-12-19 2000-09-26 University Of Nebraska-Lincoln Octafluoro-meso-tetraarylporphyrins and methods for making these compounds
DE19706490C1 (de) 1997-02-19 1998-09-17 Deutsches Krebsforsch Verfahren zur Herstellung von Säureamiden und zur Metallierung von Verbindungen und Verwendung der nach den Verfahren hergestellten Verbindungen
US5886173A (en) 1997-07-30 1999-03-23 Pharmacyclics, Inc. Metallation of macrocycles with 2,4-dicarbonyl-metal complexes
US6194566B1 (en) 1997-12-02 2001-02-27 Schering Aktiengesellschaft Process for the production of metalloporphyrin-metal complex conjugates
JP3673888B2 (ja) 1998-03-09 2005-07-20 独立行政法人科学技術振興機構 ポルフィリン類金属錯体の製造方法
DE19831217A1 (de) 1998-07-03 2000-01-05 Schering Ag Neue Porphyrinderivate, diese enthaltende pharmazeutische Mittel und ihre Verwendung in der photodynamischen Therapie und MRI-Diagnostik
US5973141A (en) 1998-11-27 1999-10-26 Miravant Pharmaceuticals, Inc. Method for the demethoxycarbonylation of porphyrinic compounds such as pheophorbides
US6462192B2 (en) 2001-01-23 2002-10-08 Miravant Pharmaceuticals, Inc. Processes for large scale production of tetrapyrroles
US20040097481A1 (en) * 2002-11-20 2004-05-20 Benjamin Levinson Water-soluble mesoporphyrin compounds and methods of preparation

Also Published As

Publication number Publication date
WO2003101999A3 (en) 2004-09-10
ZA200409670B (en) 2005-09-28
US6818763B2 (en) 2004-11-16
EP1509527A4 (en) 2006-06-28
MXPA04012045A (es) 2005-08-16
CA2487426A1 (en) 2003-12-11
JP2005528444A (ja) 2005-09-22
US20030225264A1 (en) 2003-12-04
NO20045113L (no) 2005-03-03
AU2003237349A1 (en) 2003-12-19
EP1509527A2 (en) 2005-03-02
AU2003237349B2 (en) 2010-06-03
NO333406B1 (no) 2013-05-27
NZ536666A (en) 2007-10-26
AU2006222768B2 (en) 2010-08-12
AU2006222768A1 (en) 2006-10-26
CA2487426C (en) 2010-09-07
EP2270016A1 (en) 2011-01-05
WO2003101999A2 (en) 2003-12-11
EP1509527B1 (en) 2014-05-07

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