JP4280164B2 - Ｃ２−置換インダン−１−オンおよびその誘導体、その製造方法および医薬としてのその使用 - Google Patents

Ｃ２−置換インダン−１−オンおよびその誘導体、その製造方法および医薬としてのその使用 Download PDF

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Publication number
JP4280164B2
JP4280164B2 JP2003524950A JP2003524950A JP4280164B2 JP 4280164 B2 JP4280164 B2 JP 4280164B2 JP 2003524950 A JP2003524950 A JP 2003524950A JP 2003524950 A JP2003524950 A JP 2003524950A JP 4280164 B2 JP4280164 B2 JP 4280164B2
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Japan
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alkyl
compound
cycloalkyl
formula
compounds
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JP2003524950A
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Japanese (ja)
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JP2005525295A5 (https=
JP2005525295A (ja
Inventor
ゲーアハルト・イェーネ
フォルカー・クローネ
マルティーン・ビッケル
マティーアス・ゴッセル
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サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
JP2003524950A 2001-08-31 2002-08-17 Ｃ２−置換インダン−１−オンおよびその誘導体、その製造方法および医薬としてのその使用 Expired - Fee Related JP4280164B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10142722A DE10142722A1 (de) 2001-08-31 2001-08-31 C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP2002/009207 WO2003020677A2 (de) 2001-08-31 2002-08-17 C2-substituierte indan-1-one und ihre derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
JP2005525295A JP2005525295A (ja) 2005-08-25
JP2005525295A5 JP2005525295A5 (https=) 2006-01-05
JP4280164B2 true JP4280164B2 (ja) 2009-06-17

Family

ID=7697277

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003524950A Expired - Fee Related JP4280164B2 (ja) 2001-08-31 2002-08-17 Ｃ２−置換インダン−１−オンおよびその誘導体、その製造方法および医薬としてのその使用

Country Status (12)

Country Link
US (1) US6762326B2 (https=)
EP (1) EP1425267B1 (https=)
JP (1) JP4280164B2 (https=)
AR (1) AR036675A1 (https=)
AT (1) ATE472525T1 (https=)
AU (1) AU2002336085B2 (https=)
CA (1) CA2458528C (https=)
DE (2) DE10142722A1 (https=)
IL (1) IL160608A0 (https=)
MX (1) MXPA04001846A (https=)
PE (1) PE20030360A1 (https=)
WO (1) WO2003020677A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920393D0 (en) 1999-08-27 1999-11-03 Medix Scient Uk Limited Plant extract mixtures and their uses
US7659313B2 (en) 2007-09-13 2010-02-09 Gateway Health Alliances, Inc. Methods and related compositions using specific indanes to reduce weight and inhibit lipase, α-amylase and α-glucosidase activity in mammals

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7700500L (sv) * 1976-01-20 1977-07-21 Hoechst Ag Tiazolidinderivat och forfarande for deras framstellning
DE2640358A1 (de) * 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
EP0009554B1 (de) * 1978-07-27 1983-04-27 Schering Aktiengesellschaft Indanyl-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
WO1989003681A1 (en) * 1987-10-19 1989-05-05 Pfizer Inc. Substituted tetralins, chromans and related compounds in the treatment of asthma
SG47557A1 (en) * 1993-01-29 1998-04-17 American Cyanamid Co Aminocycloalkanobenzodioxoles as beta-3 selective adrenergic agents
WO1997020802A1 (en) * 1995-12-06 1997-06-12 Venantius Limited Indane dimer compounds and their pharmaceutical use
AU727775B2 (en) 1996-01-17 2000-12-21 Novo Nordisk A/S Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
IL128332A0 (en) 1996-08-30 2000-01-31 Novo Nordisk As GLP-1 derivatives
IL127296A (en) 1996-12-31 2003-01-12 Reddy Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
PL338013A1 (en) 1997-07-16 2000-09-25 Novo Nordisk As Derivatives of condensed 1,2,4-thiadiazine, their production and application
DE19831878C2 (de) * 1998-07-17 2001-05-17 Aventis Pharma Gmbh Polycyclische Thiazolidin-2-yliden Amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19844547C2 (de) * 1998-09-29 2002-11-07 Aventis Pharma Gmbh Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19908539A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
FR2796070B1 (fr) * 1999-07-06 2003-02-21 Lipha Derives de benzodiazepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation
EP1078632A1 (en) 1999-08-16 2001-02-28 Sanofi-Synthelabo Use of monoamine oxydase inhibitors for the manufacture of drugs intended for the treatment of obesity

Also Published As

Publication number Publication date
DE10142722A1 (de) 2003-03-27
CA2458528A1 (en) 2003-03-13
AR036675A1 (es) 2004-09-29
EP1425267B1 (de) 2010-06-30
IL160608A0 (en) 2004-07-25
US20030130345A1 (en) 2003-07-10
MXPA04001846A (es) 2004-06-15
AU2002336085B2 (en) 2007-10-11
CA2458528C (en) 2011-01-25
WO2003020677A2 (de) 2003-03-13
ATE472525T1 (de) 2010-07-15
WO2003020677A3 (de) 2003-07-31
US6762326B2 (en) 2004-07-13
EP1425267A2 (de) 2004-06-09
PE20030360A1 (es) 2003-05-16
DE50214511D1 (de) 2010-08-12
JP2005525295A (ja) 2005-08-25

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