JP4262979B2 - Fgfアフィニティークロマトグラフィー - Google Patents

Fgfアフィニティークロマトグラフィー Download PDF

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Publication number
JP4262979B2
JP4262979B2 JP2002545053A JP2002545053A JP4262979B2 JP 4262979 B2 JP4262979 B2 JP 4262979B2 JP 2002545053 A JP2002545053 A JP 2002545053A JP 2002545053 A JP2002545053 A JP 2002545053A JP 4262979 B2 JP4262979 B2 JP 4262979B2
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Japan
Prior art keywords
fgf7
heparin
anticoagulant
gst
activity
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Expired - Fee Related
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English (en)
Japanese (ja)
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JP2004515575A5 (enExample
JP2004515575A (ja
Inventor
マツキーハン,ワランス・エル
ルオ,ヨンデ
Original Assignee
ザ・テキサス・エイ・アンド・エム・ユニバーシテイ・システム
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP2002545053A 2000-11-21 2001-11-21 Fgfアフィニティークロマトグラフィー Expired - Fee Related JP4262979B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25222500P 2000-11-21 2000-11-21
US27773501P 2001-03-21 2001-03-21
US32561301P 2001-09-28 2001-09-28
US32550201P 2001-09-28 2001-09-28
PCT/US2001/043817 WO2002042336A2 (en) 2000-11-21 2001-11-21 Fgf-affinity chromatography

Publications (3)

Publication Number Publication Date
JP2004515575A JP2004515575A (ja) 2004-05-27
JP2004515575A5 JP2004515575A5 (enExample) 2009-02-19
JP4262979B2 true JP4262979B2 (ja) 2009-05-13

Family

ID=27500424

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002545053A Expired - Fee Related JP4262979B2 (ja) 2000-11-21 2001-11-21 Fgfアフィニティークロマトグラフィー

Country Status (5)

Country Link
US (1) US6812221B2 (enExample)
EP (1) EP1414866A2 (enExample)
JP (1) JP4262979B2 (enExample)
AU (1) AU2002236477A1 (enExample)
WO (1) WO2002042336A2 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638312B2 (en) 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) * 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
JP2005515802A (ja) 2001-07-16 2005-06-02 デピュイ・プロダクツ・インコーポレイテッド 混成生物/合成品型多孔質細胞外基質支持骨格
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
US8337537B2 (en) 2001-07-16 2012-12-25 Depuy Products, Inc. Device from naturally occurring biologically derived materials
US8025896B2 (en) 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US20030033021A1 (en) * 2001-07-16 2003-02-13 Plouhar Pamela Lynn Cartilage repair and regeneration scaffold and method
AU2002354913B2 (en) 2001-07-16 2008-07-17 Depuy Products, Inc. Unitary surgical device and method
US7201917B2 (en) 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
WO2003007784A2 (en) 2001-07-16 2003-01-30 Depuy Products, Inc. Meniscus regeneration device and method
WO2003033512A2 (en) * 2001-10-16 2003-04-24 Procognia, Ltd. Method of preparing purified biologically active oligosaccharide libraries
US7575886B2 (en) 2002-03-11 2009-08-18 Momenta Pharmaceuticals, Inc. Analysis of sulfated polysaccharides
WO2005079817A1 (en) * 2004-02-18 2005-09-01 The Texas A & M University System Affinity purified heparin/heparan sulfate for controlling the biological activity of the fgf receptor
US7569233B2 (en) 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US7513866B2 (en) 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7354627B2 (en) 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
US20060183712A1 (en) * 2005-02-17 2006-08-17 The Texas A&M University System Affinity purified heparin/heparan sulfate for controlling the biological activity of the FGF receptor
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
US7871440B2 (en) 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US9139876B1 (en) * 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
GB0812919D0 (en) * 2008-07-15 2008-08-20 Norwegian University Of Life Sciences Process
GB0818255D0 (en) * 2008-10-06 2008-11-12 Agency Science Tech & Res Isolation and identification of glycosaminoglycans
US9498494B2 (en) 2008-09-11 2016-11-22 Agency For Science, Technology And Research Glycosaminoglycans
CN102791742B (zh) * 2010-01-19 2014-12-24 动量制药公司 评价肝素制剂
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
CN103570847B (zh) * 2013-11-15 2015-11-18 重庆三腾食品有限公司 一种肝素钠加工方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2597484B1 (fr) * 1986-04-17 1988-12-23 Sanofi Sa Glycosaminoglycanes de type heparine ou heparane-sulfate dotes d'une activite sur la division et la differentiation cellulaires, leur preparation et leurs applications therapeutiques.
JP3039802B2 (ja) 1989-07-06 2000-05-08 ザ リージェンツ オブザ ユニバーシティ オブ カリフォルニア 繊維芽細胞成長因子のための受容体
WO1991009126A1 (en) * 1989-12-19 1991-06-27 Takeda Chemical Industries, Ltd. Production of human basic fgf mutein
AUPN271295A0 (en) 1995-05-02 1995-05-25 Gropep Pty Ltd Method of treatment
FI921689A7 (fi) * 1991-04-16 1992-10-17 Seikakagu Kogyo Kk Fibroblastikasvutekijän suhteen affiniteetin omaava oligosakkaridi ja menetelmä sen valmistamiseksi
US5807982A (en) 1991-04-29 1998-09-15 Cornell Research Foundation, Inc. Affinity purified heparin
GB2293590B (en) 1993-03-01 1997-03-26 Kawasaki Steel Co A Stacker Crane having a Fork-lift Apparatus
US5965530A (en) 1993-03-26 1999-10-12 Amgen Inc. Therapeutic uses of keratinocyte growth factor
DK0706563T3 (da) 1993-06-29 2005-01-31 Chiron Corp Afkortet keratonocyt-vækstfaktor (KGF) med foröget biologisk aktivetet
US6127347A (en) 1994-01-12 2000-10-03 Univ Michigan Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes
WO1995030424A1 (en) * 1994-05-06 1995-11-16 Glycomed Incorporated O-desulfated heparin derivatives, methods of making and uses thereof
US5733893A (en) 1995-03-15 1998-03-31 Washington University Method of identifying molecules that regulate FGF activity
US5801063A (en) 1995-05-09 1998-09-01 Grandics; Peter Device and process for the biospecific removal of heparin
US5814485A (en) * 1995-06-06 1998-09-29 Chiron Corporation Production of interferon-β (IFN-β) in E. coli
JP2003521483A (ja) * 1999-11-11 2003-07-15 エイエム ファーマ ビーブイ ヒトラクトフェリンの第1カチオンクラスターの抗菌活性

Also Published As

Publication number Publication date
AU2002236477A1 (en) 2002-06-03
WO2002042336A3 (en) 2004-02-26
US20020111331A1 (en) 2002-08-15
JP2004515575A (ja) 2004-05-27
WO2002042336A2 (en) 2002-05-30
EP1414866A2 (en) 2004-05-06
US6812221B2 (en) 2004-11-02

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