JP4215224B2 - Method for producing chitin powder or granule or chitosan powder or granule - Google Patents
Method for producing chitin powder or granule or chitosan powder or granule Download PDFInfo
- Publication number
- JP4215224B2 JP4215224B2 JP34767098A JP34767098A JP4215224B2 JP 4215224 B2 JP4215224 B2 JP 4215224B2 JP 34767098 A JP34767098 A JP 34767098A JP 34767098 A JP34767098 A JP 34767098A JP 4215224 B2 JP4215224 B2 JP 4215224B2
- Authority
- JP
- Japan
- Prior art keywords
- powder
- chitin
- chitosan
- dryer
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Description
【０００１】
【発明の属する技術分野】
本発明は含水キチン粉末又は含水キトサン粉末に回転運動を与えた後に乾燥する事で、嵩比重、粉体流動性、油分散性を改善し、錠剤、ソフトカプセル、顆粒などのいわゆる健康食品原料としての加工特性を改善する技術に関するものである。
【従来の技術】
【０００２】
キチンはカニ、エビ等の甲殻類の甲皮等、昆虫の甲殻、キノコ、糸状菌等の細胞壁に含まれる食物繊維で、保水性を有することから便通改善効果を示す。また、キトサンはキチンをさらにアルカリ処理することで脱アセチル化を行い得られる物質で、コレステロール調整機能、血圧上昇抑制機能、糞便中の有害物質濃度低減作用など様々な生理機能を有する食物繊維であり、キチンは食物繊維源として、キトサンは生活習慣病を予防する機能性食材として食品分野、特に手軽に摂取できる錠剤、ソフトカプセル、顆粒などのいわゆる健康食品に加工されることが多い。
【０００３】
キチン又はキトサンは工業的にはカニ、エビ等の甲殻類の甲皮等から製造されるが、得られたキチン、キトサンは嵩比重が小さく、粉体流動性が悪いため錠剤、顆粒等には加工しにくく、油分散性が悪いためソフトカプセルに充填する量が限られる。
【０００４】
この様な場合、キチン粉末又はキトサン粉末を水分と接触させた後、そのまま棚式乾燥機などで乾燥したり、混合機能を有する乾燥機すなわち、ナウター乾燥機やコニカル乾燥機、スクリュー式乾燥機で乾燥することでこれらの物性を改善することができる。（特開平８−２６９１０４）
【０００５】
【発明が解決しようとする課題】
しかしながら、水分と接触させた後そのまま棚式乾燥をする場合、嵩比重が０．２０ｇ／ｍｌ程度にしか改善されない。混合機能を有する乾燥機すなわち、ナウター乾燥機やコニカル乾燥機、スクリュー式乾燥機は嵩比重を０．２０ｇ／ｍｌ以上にすることが可能であるが、広い設置場所が必要であることに加え、機器の価格も高価であり、一般の健康食品製造工場では実施が難しい。
これらの事から、一般の健康食品製造工場で製造する事が可能で安価なキチン粉末又は顆粒又はキトサン粉末又は顆粒の製造方法が望まれていた。
本発明の目的は、キチン粉末又はキトサン粉末の嵩比重、粉体流動性、油分散性を改善する方法を提供することにある。
【０００６】
【課題を解決するための手段】
そこで本発明者らは、種々検討した結果、含水キチン粉末又は含水キトサン粉末に回転運動を与えた後に乾燥することにより嵩比重が０．２５ｇ／ｍｌ以上となり、かつ粉体流動性や油分散性が改善されることを見出した。
【０００７】
即ち、本発明は、
（１）含水キチン粉末又は含水キトサン粉末に回転運動を与えた後、乾燥する事を特徴とする物性の改良されたキチン粉末又は顆粒又はキトサン粉末又は顆粒の製造方法、
（２）含水キチン粉末又は含水キトサン粉末の含水率が２０％から４５％の範囲である（１）記載の方法
（３）含水キチン粉末又は含水キトサン粉末に回転運動を与える時間が１〜６０分間である（１）又は（２）記載の方法
（４）含水キチン粉末又は含水キトサン粉末が４５％を超える含水量のキチン粉末又はキトサン粉末を部分乾燥して得られたものである（２）記載の方法
（５）２０％を超えて４５％までの含水量のキチン粉末又はキトサン粉末を水分量が２０％から４５％未満になるように部分乾燥し、回転運動を与えた後、更に乾燥する事を特徴とするキチン粉末又は顆粒又はキトサン粉末又は顆粒の製造方法
（６）乾燥方法が自然乾燥、天日乾燥、棚式乾燥機、透過式乾燥機、凍結乾燥機又は減圧乾燥機を使用する乾燥である（１）〜（５）のいずれかに記載の方法
（７）回転運動を与える方法がＶ型混合機、混合パン、リボンミキサ−、ナウタ−混合機又はコニカル混合機を用いるものである（１）〜（６）のいずれかに記載の方法
、に関する。
【０００８】
【発明の実施の形態】
本発明で用いられるキチン、キトサンの起源は海老、蟹、シャコ、イカ等、特に制限はなく、粉末の平均粒子径は、３００μｍ以下の粉末であれば何れでも良いが、好ましくは３０〜１８０μｍである。
【０００９】
キチン粉末又はキトサン粉末に含まれる水としては、工業用水、水道水、ミネラル水、純水等、水であれば如何なる水であっても良い。又、水は蒸気、氷結水等に加工して用いても良い。又、含水溶媒であってもよく、その溶媒の種類としては、例えば、アセトン、メタノ−ル、エチルアルコール等の水溶性溶媒が挙げられ、キチン、キトサンを溶解しないものであれば何れでもよい。又、キチン粉末又はキトサン粉末の製造の際に得られる未乾燥の含水キチン粉末又は含水キトサン粉末をそのまま用いてもよい。
【００１０】
また、水にメチルセルロース、アラビアガム、糊化デンプンなどの結着剤を溶解した後、これをキチン粉末又はキトサン粉末に加え均一に混合して使用する事により、打錠用に顆粒を製造する事もでき、粉末を製造する事もできる。
【００１１】
本発明で含水キチン粉末又は含水キトサン粉末に含まれる水の量としては、含水キチン粉末又は含水キトサン粉末の全体重量に対して２０％から４５％の範囲が好ましく、より好ましくは３５％から４５％の範囲である。また、含水率が４５％を超えるキチン粉末又はキトサン粉末を水分が２０％から４５％の範囲まで部分乾燥、又は、含水率が２０％を超えて４５％までのキチン粉末又はキトサン粉末を水分量が２０％から４５％未満になるように部分乾燥した後、取り出し、混合機で回転運動を与えた後に、更に乾燥を行っても良いし、回転運動を与えた後、別の乾燥方法によって再び乾燥を再開する事もできる。
【００１２】
回転運動を与える方法としては特に制限はないが、Ｖ型混合機、混合パン、リボンミキサー、ナウター混合機、コニカル混合機等の粉体混合機を使用する事が好ましく、減圧状態で回転運動を与える事もでき、少量であればビニール袋に空気と共に封入し手で混合しながら回転運動を行ってもよい。また、回転を与える時の温度は特に制限はなく、また回転運動を行う時間は通常１分間以上であれば良く、好ましくは１〜６０分間、より好ましくは１〜３０分間、特に好ましくは５〜１０分間である。
【００１３】
本発明に用いる乾燥は、自然乾燥や天日乾燥、または乾燥機を使用する事ができる。乾燥機を使用する場合は棚式乾燥機、透過式乾燥機、凍結乾燥機、減圧乾燥機等、静置状態で乾燥する乾燥機であれば如何なる乾燥機を用いてもよく、一般の健康食品製造工場に設置されている乾燥機も使用できる。
【００１４】
乾燥機の温度は乾燥機内の温度がキチン粉末又は顆粒又はキトサン粉末又は顆粒を変質させない温度であれば特に制限はないが、効率等の点から乾燥機内の温度は３０〜１８０℃が好ましく、より好ましくは６０〜１５０℃であり、特に好ましくは８０〜１２０℃である。
【００１５】
【発明の効果】
本発明のすぐれた効果を以下の実験により示す。実験試料はキトサン粉末を８０メッシュの篩いを全量通過するまで粉砕し用いた。
【００１６】
結果
結果を下記表に示す
【００１８】
【表１】
この実験結果より明らかなように、含水キチン粉末又は含水キトサン粉末に、好ましくは水分含量が２０％から４５％、より好ましくは３５％から４５％のときに回転運動を与える事でキチン粉末又はキトサン粉末の嵩比重、粉体流動性、油分散性が改善され、錠剤、ソフトカプセル、顆粒などのいわゆる健康食品原料としての最適な粉末が得られた。
【００２０】
【実施例】
以下に実施例を挙げて本発明を具体的に説明するが、本発明はこれらに限定されるものではない。
実施例１
５０メッシュの篩いを全通するように粉砕したキチン粉末（嵩比重０．１９５ｇ／ｍｌ）４８ｋｇに水３４ｋｇを加えてスピードニーダーで５分間練合した後、８０℃の棚式乾燥機で乾燥減量が３８％になるまで乾燥し、混合パンに移しかえて１５分間、１５ｒｐｍで回転運動を与えた後、再び８０℃で乾燥することで、キチン粉末の嵩比重を０．１９５ｇ／ｍｌから０．２６７ｇ／ｍｌに改善した。
【００２１】
実施例２
８０メッシュの篩いを全通するように粉砕したキトサン粉末（嵩比重０．１６ｇ／ｍｌ）２０ｋｇにメチルセルロース１ｋｇを加え混合パンで１分間混合した後、水２０ｋｇを加え、スピードニーダーで３分間練合し、スピードミルで整粒後、Ｖ型混合機で５分間回転を与えた後、６０℃の真空乾燥機で乾燥し１４メッシュの篩いで篩過することで打錠用顆粒を得た。得られた顆粒は、嵩比重が０．１６ｇ／ｍｌから０．２７ｇ／ｍｌに改善され、粉体流動性も良好であった。
【００２２】
実施例３
１５０メッシュの篩いを全通するように粉砕したキトサン粉末（嵩比重０．１５５ｇ／ｍｌ）５０ｋｇに、水６０ｋｇ加え２０分間混合した後、８０℃の透過式乾燥機で水分含量を３５％まで乾燥した。乾燥後、混合パンに取りだし２０分間１５ｒｐｍで回転運動を与えた後、再び８０℃の透過式乾燥機で乾燥減量７％以下になるまで乾燥し１４メッシュの篩いで篩過することでキトサン顆粒の嵩比重を０．１５５ｇ／ｍｌから０．３０４ｇ／ｍｌに改善した。
【００２３】
実施例４
８０メッシュの篩いを全通するように粉砕したキチン粉末１ｋｇ及びキトサン粉末１ｋｇの混合物（安息角４９度）を混合パンで１分間混合した後、水２ｋｇを加えスピードニーダーで５分間練合後、５０Ｌのビニール袋に取りだし空気を封入し、手で混合しながら５分間回転運動を与えた。その後、６０℃の減圧乾燥機乾燥で水分３％にまで乾燥し、キチン粉末及びキトサン粉末混合物の安息角を４９度から４５度に改善した。
【００２４】
実施例５
５０メッシュの篩いを全通するように粉砕したキトサン粉末（嵩比重０．１７０ｇ／ｍｌ）４８ｋｇに水９０ｋｇを加えてスピードニーダーで５分間練合した後、８０℃の棚式乾燥機で乾燥減量が３８％になるまで乾燥し、混合パンに移しかえて１０分間、１５ｒｐｍで回転運動を与えた後、再び８０℃で乾燥することで、キチン粉末の嵩比重を０．１７０ｇ／ｍｌから０．２９０ｇ／ｍｌに改善した。[0001]
BACKGROUND OF THE INVENTION
The present invention improves the bulk specific gravity, powder fluidity, and oil dispersibility by applying a rotational motion to the hydrous chitin powder or hydrous chitosan powder, thereby improving the bulk specific gravity, powder flowability, and oil dispersibility, and as a so-called health food ingredient for tablets, soft capsules, granules, etc. The present invention relates to a technique for improving processing characteristics.
[Prior art]
[0002]
Chitin is a dietary fiber contained in the cell walls of crustacean shells such as crabs and shrimps, insect shells, mushrooms, filamentous fungi and the like, and has water retention, and thus has an effect of improving bowel movement. Chitosan is a substance that can be deacetylated by further treating chitin with alkali, and is a dietary fiber that has various physiological functions such as cholesterol regulation, blood pressure increase suppression, and fecal harmful substance concentration reduction. Chitin is often used as a dietary fiber source and chitosan as a functional food for preventing lifestyle-related diseases, and is often processed into so-called health foods such as tablets, soft capsules, and granules that can be easily consumed.
[0003]
Chitin or chitosan is industrially produced from the shells of crustaceans such as crabs and shrimps, but the obtained chitin and chitosan have low bulk specific gravity and poor powder flowability. Difficult to process and poor oil dispersibility, so the amount of soft capsules is limited.
[0004]
In such a case, after the chitin powder or chitosan powder is brought into contact with moisture, the chitin powder or chitosan powder is directly dried by a shelf dryer or the like, or a dryer having a mixing function, that is, a nauter dryer, a conical dryer, or a screw dryer. These physical properties can be improved by drying. (JP-A-8-269104)
[0005]
[Problems to be solved by the invention]
However, when shelf drying is performed as it is after contact with moisture, the bulk specific gravity is improved only to about 0.20 g / ml. A dryer having a mixing function, that is, a Nauter dryer, a conical dryer, and a screw-type dryer can have a bulk specific gravity of 0.20 g / ml or more. The price of the equipment is also expensive and difficult to implement at a general health food manufacturing factory.
From these facts, an inexpensive method for producing chitin powder or granule or chitosan powder or granule that can be produced in a general health food manufacturing factory has been desired.
An object of the present invention is to provide a method for improving the bulk specific gravity, powder flowability, and oil dispersibility of chitin powder or chitosan powder.
[0006]
[Means for Solving the Problems]
Therefore, as a result of various investigations, the present inventors have determined that the bulk specific gravity becomes 0.25 g / ml or more by drying the hydrous chitin powder or hydrous chitosan powder after giving a rotational motion, and the powder fluidity and oil dispersibility. Found to be improved.
[0007]
That is, the present invention
(1) A method for producing chitin powder or granule or chitosan powder or granule having improved physical properties, characterized in that hydrochitin powder or hydrous chitosan powder is subjected to rotational movement and then dried.
(2) The method according to (1), wherein the water content of the hydrous chitin powder or the hydrous chitosan powder is in the range of 20% to 45%. (3) The time for giving the rotational motion to the hydrous chitin powder or the hydrous chitosan powder is 1 to 60 minutes. The method according to (1) or (2), wherein the water-containing chitin powder or the water-containing chitosan powder is obtained by partially drying a chitin powder or chitosan powder having a water content of more than 45%. Method (5) Chitin powder or chitosan powder having a water content exceeding 20% and up to 45% is partially dried so that the water content is 20% to less than 45%, and after being subjected to rotational motion, it is further dried. Chitin powder or granule or chitosan powder or granule production method characterized in that (6) Drying method uses natural drying, sun drying, shelf dryer, permeation dryer, freeze dryer or vacuum dryer Is dry ( (7) The method according to any one of (5) to (5) is a method using a V-type mixer, a mixing pan, a ribbon mixer, a nauta-mixer or a conical mixer. The method according to any one of (6).
[0008]
DETAILED DESCRIPTION OF THE INVENTION
The origin of chitin and chitosan used in the present invention is not particularly limited, such as shrimp, salmon, giant clam, squid, etc. The average particle size of the powder may be any powder as long as it is 300 μm or less, preferably 30 to 180 μm. is there.
[0009]
The water contained in the chitin powder or chitosan powder may be any water as long as it is water such as industrial water, tap water, mineral water, or pure water. Further, water may be used after being processed into steam, frozen water, or the like. Further, it may be a hydrous solvent, and examples of the solvent include water-soluble solvents such as acetone, methanol, and ethyl alcohol, and any solvent that does not dissolve chitin and chitosan may be used. Moreover, you may use the undried hydrous chitin powder or hydrous chitosan powder obtained in the case of manufacture of a chitin powder or a chitosan powder as it is.
[0010]
In addition, after dissolving a binder such as methylcellulose, gum arabic, and gelatinized starch in water, it is added to chitin powder or chitosan powder and mixed uniformly to produce granules for tableting. It is also possible to produce powder.
[0011]
In the present invention, the amount of water contained in the hydrated chitin powder or hydrated chitosan powder is preferably in the range of 20% to 45%, more preferably 35% to 45%, based on the total weight of the hydrated chitin powder or hydrated chitosan powder. Range. In addition, the chitin powder or chitosan powder having a moisture content exceeding 45% is partially dried from 20% to 45%, or the chitin powder or chitosan powder having a moisture content exceeding 20% to 45% is moisture content. May be partially dried so as to be 20% to less than 45%, and then taken out and given a rotational motion with a mixer, then further drying may be performed, or after giving a rotational motion, another drying method may be used again. Drying can be resumed.
[0012]
There are no particular restrictions on the method of imparting rotational motion, but it is preferable to use a powder mixer such as a V-type mixer, mixing pan, ribbon mixer, nauter mixer, conical mixer, etc. If it is a small amount, it may be enclosed with air in a plastic bag and rotated while mixing by hand. The temperature at which the rotation is applied is not particularly limited, and the time for performing the rotational motion is usually 1 minute or more, preferably 1 to 60 minutes, more preferably 1 to 30 minutes, and particularly preferably 5 to 5 minutes. 10 minutes.
[0013]
The drying used in the present invention can be natural drying, sun drying, or a dryer. When using a dryer, any dryer may be used as long as it is a stationary dryer such as a shelf dryer, a permeation dryer, a freeze dryer, a vacuum dryer, etc. A dryer installed in the manufacturing plant can also be used.
[0014]
The temperature of the dryer is not particularly limited as long as the temperature in the dryer does not change the quality of chitin powder or granules or chitosan powder or granules, but the temperature in the dryer is preferably 30 to 180 ° C from the viewpoint of efficiency, etc. Preferably it is 60-150 degreeC, Most preferably, it is 80-120 degreeC.
[0015]
【The invention's effect】
The excellent effect of the present invention is shown by the following experiment. As the experimental sample, chitosan powder was pulverized until it passed through an 80-mesh sieve.
[0016]
The results are shown in the table below.
[Table 1]
As is clear from this experimental result, the chitin powder or chitosan is given to the hydrous chitin powder or the hydrous chitosan powder by giving a rotational motion when the water content is preferably 20% to 45%, more preferably 35% to 45%. The bulk specific gravity, powder fluidity, and oil dispersibility of the powder were improved, and an optimal powder as a so-called health food material such as tablets, soft capsules and granules was obtained.
[0020]
【Example】
EXAMPLES The present invention will be specifically described below with reference to examples, but the present invention is not limited to these examples.
Example 1
After adding 34 kg of water to 48 kg of chitin powder (bulk specific gravity 0.195 g / ml) pulverized to pass through a 50-mesh sieve, kneading with a speed kneader for 5 minutes, and then drying loss with an 80 ° C shelf dryer The mixture was transferred to a mixing pan and given a rotational motion at 15 rpm for 15 minutes and then dried again at 80 ° C., whereby the bulk specific gravity of the chitin powder was reduced from 0.195 g / ml to 0.1%. Improved to 267 g / ml.
[0021]
Example 2
Add 1 kg of methylcellulose to 20 kg of chitosan powder (bulk specific gravity 0.16 g / ml) that has been crushed to pass through an 80-mesh sieve, mix for 1 minute in a mixing pan, add 20 kg of water, and knead for 3 minutes with a speed kneader. After granulating with a speed mill, the mixture was rotated for 5 minutes with a V-type mixer, dried with a vacuum dryer at 60 ° C., and sieved with a 14-mesh sieve to obtain granules for tableting. The obtained granules had an improved bulk specific gravity from 0.16 g / ml to 0.27 g / ml and good powder flowability.
[0022]
Example 3
Add 50 kg of water to 50 kg of chitosan powder (bulk specific gravity 0.155 g / ml) ground to pass through a 150-mesh sieve, mix for 20 minutes, and dry to a moisture content of 35% with a 80 ° C permeation dryer. did. After drying, the mixture is taken out to a mixing pan and subjected to a rotational motion at 15 rpm for 20 minutes, then dried again with a transmission dryer at 80 ° C. until the loss on drying becomes 7% or less, and sieved with a 14 mesh sieve to obtain chitosan granules. The bulk specific gravity was improved from 0.155 g / ml to 0.304 g / ml.
[0023]
Example 4
A mixture of 1 kg of chitin powder and 1 kg of chitosan powder crushed to pass through an 80-mesh sieve (repose angle 49 degrees) was mixed for 1 minute in a mixing pan, then 2 kg of water was added and kneaded for 5 minutes with a speed kneader. It was taken out into a 50 L plastic bag, filled with air, and rotated for 5 minutes while mixing by hand. Then, it dried to 60% of moisture by 60 degreeC vacuum dryer drying, and improved the repose angle of the chitin powder and chitosan powder mixture from 49 degree | times to 45 degree | times.
[0024]
Example 5
After adding 90 kg of water to 48 kg of chitosan powder (bulk specific gravity 0.170 g / ml) ground so as to pass through a 50 mesh sieve, knead with a speed kneader for 5 minutes, and then dry weight loss with a shelf dryer at 80 ° C. Was dried until it reached 38%, transferred to a mixing pan, subjected to rotational movement at 15 rpm for 10 minutes, and then dried again at 80 ° C., whereby the bulk specific gravity of the chitin powder was reduced from 0.170 g / ml to 0.1%. Improved to 290 g / ml.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34767098A JP4215224B2 (en) | 1998-07-01 | 1998-12-08 | Method for producing chitin powder or granule or chitosan powder or granule |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10-185506 | 1998-07-01 | ||
| JP18550698 | 1998-07-01 | ||
| JP34767098A JP4215224B2 (en) | 1998-07-01 | 1998-12-08 | Method for producing chitin powder or granule or chitosan powder or granule |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000080104A JP2000080104A (en) | 2000-03-21 |
| JP4215224B2 true JP4215224B2 (en) | 2009-01-28 |
Family
ID=26503147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP34767098A Expired - Fee Related JP4215224B2 (en) | 1998-07-01 | 1998-12-08 | Method for producing chitin powder or granule or chitosan powder or granule |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4215224B2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100470715B1 (en) * | 2002-04-04 | 2005-03-08 | 주식회사 자광 | A capsule of porous bead of water soluble chitosan and the preparation method thereof |
| KR100679750B1 (en) * | 2005-09-14 | 2007-02-06 | 김진만 | Supplementary food composition for reducing body odor |
| US7943597B2 (en) * | 2008-04-08 | 2011-05-17 | Cypress Pharmaceutical, Inc. | Phosphate-binding chitosan and uses thereof |
| JP5969680B1 (en) * | 2015-10-28 | 2016-08-17 | 日本化薬フードテクノ株式会社 | Chitosan powder, method for producing the same, and preparation containing chitosan |
| JP6907160B2 (en) * | 2018-06-22 | 2021-07-21 | 大日精化工業株式会社 | Method for manufacturing easily dispersible compression molded product |
| JP6823620B2 (en) * | 2018-06-22 | 2021-02-03 | 大日精化工業株式会社 | I Ching compression molded product and its manufacturing method |
-
1998
- 1998-12-08 JP JP34767098A patent/JP4215224B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000080104A (en) | 2000-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS6012958A (en) | Easily dispersible food fiber product and production thereof | |
| JP4215224B2 (en) | Method for producing chitin powder or granule or chitosan powder or granule | |
| KR100393092B1 (en) | Noodles prepared containing hydrated kitosan regenerating | |
| JPH03164147A (en) | Food material and production thereof | |
| JP2002187842A (en) | Processed product of kale and method for processing the same | |
| JPH0586227A (en) | Water-soluble dietary fiber complex and food composition containing the same | |
| JP4140741B2 (en) | Method for producing dry chitin powder or dry chitosan powder | |
| JP3737881B2 (en) | Chitosan composition and method for producing the same | |
| JP3046105B2 (en) | Chitosan-plant fiber composite and method for preparing the same | |
| JPS6152740B2 (en) | ||
| JP4178361B2 (en) | Chitosan-containing powder | |
| JP3105066B2 (en) | Granular organic fertilizer composition | |
| JP5888845B2 (en) | Easy dispersible granular food | |
| JP3565666B2 (en) | Improved edible pollen and its production method | |
| JP4844901B2 (en) | Chitosan-containing powder | |
| JP2004201569A (en) | Method for producing mannan mixture | |
| JP3231276B2 (en) | Chitosan composition and method for producing the same | |
| JPH08196242A (en) | Seasoning agent combining supply of chitosan | |
| JPH10225285A (en) | Lubricant, tablet and its production | |
| JP4647524B2 (en) | Dried konjac | |
| KR20120082286A (en) | Chitomook | |
| JP2003333968A (en) | Pellet for hera-crucian fishing | |
| JPH0820556A (en) | Production of powdered lactic acid and/or lactic acid salt | |
| JP2010248108A (en) | Method for producing sodium ascorbate granule for direct compression | |
| JP3479225B2 (en) | Water-soluble chitosan-containing granules and method for producing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20041224 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080820 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081009 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20081030 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20081031 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20111114 Year of fee payment: 3 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20141114 Year of fee payment: 6 |
|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |