JP4205306B2 - 縫合することなく生物接着剤を使用して吻合する技術及びそのための装置 - Google Patents
縫合することなく生物接着剤を使用して吻合する技術及びそのための装置 Download PDFInfo
- Publication number
- JP4205306B2 JP4205306B2 JP2000513506A JP2000513506A JP4205306B2 JP 4205306 B2 JP4205306 B2 JP 4205306B2 JP 2000513506 A JP2000513506 A JP 2000513506A JP 2000513506 A JP2000513506 A JP 2000513506A JP 4205306 B2 JP4205306 B2 JP 4205306B2
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- Prior art keywords
- elongated
- distal end
- balloon
- proximal
- distal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000227 bioadhesive Substances 0.000 title claims abstract description 38
- 238000000034 method Methods 0.000 title abstract description 31
- 210000000056 organ Anatomy 0.000 claims abstract description 65
- 239000012530 fluid Substances 0.000 claims abstract description 5
- 230000003872 anastomosis Effects 0.000 claims description 50
- 239000000463 material Substances 0.000 claims description 11
- 102000004169 proteins and genes Human genes 0.000 claims description 10
- 108090000623 proteins and genes Proteins 0.000 claims description 10
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical group O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims description 8
- 238000005553 drilling Methods 0.000 claims description 6
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims description 4
- 229940098773 bovine serum albumin Drugs 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 239000003431 cross linking reagent Substances 0.000 claims description 3
- 239000004971 Cross linker Substances 0.000 claims 3
- 239000003364 biologic glue Substances 0.000 claims 2
- 229920001744 Polyaldehyde Polymers 0.000 claims 1
- 239000012056 semi-solid material Substances 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 description 23
- 238000001356 surgical procedure Methods 0.000 description 20
- 210000003462 vein Anatomy 0.000 description 18
- 210000002216 heart Anatomy 0.000 description 11
- 210000001367 artery Anatomy 0.000 description 9
- 230000002792 vascular Effects 0.000 description 9
- 210000004351 coronary vessel Anatomy 0.000 description 8
- 239000007788 liquid Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 230000000747 cardiac effect Effects 0.000 description 7
- 210000001519 tissue Anatomy 0.000 description 7
- 239000000853 adhesive Substances 0.000 description 6
- 230000001070 adhesive effect Effects 0.000 description 6
- 238000010009 beating Methods 0.000 description 6
- 230000002357 endometrial effect Effects 0.000 description 6
- 210000003752 saphenous vein Anatomy 0.000 description 5
- 108010088751 Albumins Proteins 0.000 description 4
- 102000009027 Albumins Human genes 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 210000001198 duodenum Anatomy 0.000 description 3
- 210000002751 lymph Anatomy 0.000 description 3
- 238000002679 ablation Methods 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 230000003881 arterial anastomosis Effects 0.000 description 2
- 210000000013 bile duct Anatomy 0.000 description 2
- 210000001072 colon Anatomy 0.000 description 2
- 210000000232 gallbladder Anatomy 0.000 description 2
- 210000003405 ileum Anatomy 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 210000000277 pancreatic duct Anatomy 0.000 description 2
- 210000000664 rectum Anatomy 0.000 description 2
- 238000002271 resection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000008733 trauma Effects 0.000 description 2
- 210000000626 ureter Anatomy 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000033809 Suppuration Diseases 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 229940035674 anesthetics Drugs 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000013171 endarterectomy Methods 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000003736 gastrointestinal content Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000001630 jejunum Anatomy 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 210000001349 mammary artery Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000001819 pancreatic juice Anatomy 0.000 description 1
- 210000003516 pericardium Anatomy 0.000 description 1
- 210000004303 peritoneum Anatomy 0.000 description 1
- 210000004224 pleura Anatomy 0.000 description 1
- 229910052705 radium Inorganic materials 0.000 description 1
- HCWPIIXVSYCSAN-UHFFFAOYSA-N radium atom Chemical compound [Ra] HCWPIIXVSYCSAN-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000001562 sternum Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 210000001042 thoracic artery Anatomy 0.000 description 1
- 210000000779 thoracic wall Anatomy 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000003878 venous anastomosis Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/00491—Surgical glue applicators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00535—Surgical instruments, devices or methods pneumatically or hydraulically operated
- A61B2017/00557—Surgical instruments, devices or methods pneumatically or hydraulically operated inflatable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00681—Aspects not otherwise provided for
- A61B2017/00725—Calibration or performance testing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
- A61B2017/1107—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis for blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
- A61B2017/1139—Side-to-side connections, e.g. shunt or X-connections
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6008697P | 1997-09-26 | 1997-09-26 | |
| US60/060,086 | 1997-09-26 | ||
| PCT/US1998/020071 WO1999016359A1 (en) | 1997-09-26 | 1998-09-25 | Sutureless anastomotic technique using a bioadhesive and device therefor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001517524A JP2001517524A (ja) | 2001-10-09 |
| JP2001517524A5 JP2001517524A5 (de) | 2006-01-05 |
| JP4205306B2 true JP4205306B2 (ja) | 2009-01-07 |
Family
ID=22027251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000513506A Expired - Fee Related JP4205306B2 (ja) | 1997-09-26 | 1998-09-25 | 縫合することなく生物接着剤を使用して吻合する技術及びそのための装置 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6685726B2 (de) |
| EP (2) | EP1584292B1 (de) |
| JP (1) | JP4205306B2 (de) |
| KR (1) | KR20010023218A (de) |
| AT (1) | ATE520356T1 (de) |
| AU (1) | AU748152C (de) |
| CA (1) | CA2299407C (de) |
| ES (1) | ES2368847T3 (de) |
| WO (1) | WO1999016359A1 (de) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1230902A1 (de) * | 1996-11-15 | 2002-08-14 | Advanced Bio Surfaces, Inc. | Biomateralsystem für in-situ Gewebewiederherstellung |
| NL1007349C2 (nl) * | 1997-10-24 | 1999-04-27 | Suyker Wilhelmus Joseph Leonardus | Systeem voor het mechanisch vervaardigen van anastomoses tussen holle structuren; alsmede inrichting en applicator voor gebruik daarbij. |
| US6468203B2 (en) | 2000-04-03 | 2002-10-22 | Neoguide Systems, Inc. | Steerable endoscope and improved method of insertion |
| US6610007B2 (en) | 2000-04-03 | 2003-08-26 | Neoguide Systems, Inc. | Steerable segmented endoscope and method of insertion |
| US8517923B2 (en) | 2000-04-03 | 2013-08-27 | Intuitive Surgical Operations, Inc. | Apparatus and methods for facilitating treatment of tissue via improved delivery of energy based and non-energy based modalities |
| US6858005B2 (en) | 2000-04-03 | 2005-02-22 | Neo Guide Systems, Inc. | Tendon-driven endoscope and methods of insertion |
| US8888688B2 (en) | 2000-04-03 | 2014-11-18 | Intuitive Surgical Operations, Inc. | Connector device for a controllable instrument |
| US6464665B1 (en) * | 2000-07-05 | 2002-10-15 | Richard R. Heuser | Catheter apparatus and method for arterializing a vein |
| US6953464B2 (en) * | 2001-02-21 | 2005-10-11 | Novare Surgical Systems, Inc. | Anastomosis occlusion device |
| US7338505B2 (en) | 2002-01-09 | 2008-03-04 | Neoguide Systems, Inc. | Apparatus and method for endoscopic colectomy |
| NL1020288C1 (nl) | 2002-04-02 | 2003-05-07 | Eric Berreklouw | Samenstel omvattende een stabilisator en een in of rondom een door lichaamsweefsel, omgeven doorgang te positioneren instrument. |
| CA2489507C (en) * | 2002-06-20 | 2010-10-19 | Tyco Healthcare Group, Lp | Method and apparatus for anastomosis including an anchoring sleeve |
| US20040087993A1 (en) * | 2002-08-06 | 2004-05-06 | Shyh-Jen Wang | Auxiliary surgery tool for protruding resected part |
| US9307991B2 (en) | 2002-08-22 | 2016-04-12 | Ams Research, Llc | Anastomosis device and related methods |
| US8764775B2 (en) | 2002-08-22 | 2014-07-01 | Ams Research Corporation | Anastomosis device and related methods |
| US8551126B2 (en) | 2002-08-22 | 2013-10-08 | Ams Research Corporation | Anastomosis device and related methods |
| US8882657B2 (en) | 2003-03-07 | 2014-11-11 | Intuitive Surgical Operations, Inc. | Instrument having radio frequency identification systems and methods for use |
| US7217294B2 (en) | 2003-08-20 | 2007-05-15 | Histogenics Corp. | Acellular matrix implants for treatment of articular cartilage, bone or osteochondral defects and injuries and method for use thereof |
| US8425539B2 (en) | 2004-04-12 | 2013-04-23 | Xlumena, Inc. | Luminal structure anchoring devices and methods |
| US12303105B2 (en) | 2004-04-12 | 2025-05-20 | Boston Scientific Scimed, Inc. | Luminal structure anchoring devices and methods |
| US7515970B2 (en) * | 2004-08-18 | 2009-04-07 | Cardiac Pacemakers, Inc. | Transeptal lead |
| US20060111698A1 (en) * | 2004-11-22 | 2006-05-25 | Kihong Kwon | Apparatus and method for performing laser-assisted vascular anastomoses |
| WO2006062996A2 (en) | 2004-12-08 | 2006-06-15 | Kenneth Binmoeller | Method and apparatus for performing needle guided interventions |
| US8636756B2 (en) | 2005-02-18 | 2014-01-28 | Ams Research Corporation | Anastomosis device and surgical tool actuation mechanism configurations |
| US20060253198A1 (en) * | 2005-05-03 | 2006-11-09 | Disc Dynamics, Inc. | Multi-lumen mold for intervertebral prosthesis and method of using same |
| US20060253199A1 (en) * | 2005-05-03 | 2006-11-09 | Disc Dynamics, Inc. | Lordosis creating nucleus replacement method and apparatus |
| US7645288B2 (en) * | 2005-05-05 | 2010-01-12 | Ethicon Endo-Surgery, Inc. | Anastomotic ring applier with inflatable members |
| US7771443B2 (en) | 2005-05-20 | 2010-08-10 | Ams Research Corporation | Anastomosis device approximating structure configurations |
| US7717928B2 (en) | 2005-05-20 | 2010-05-18 | Ams Research Corporation | Anastomosis device configurations and methods |
| US8777967B2 (en) | 2005-06-09 | 2014-07-15 | Xlumena, Inc. | Methods and devices for anchoring to tissue |
| US8784437B2 (en) | 2005-06-09 | 2014-07-22 | Xlumena, Inc. | Methods and devices for endosonography-guided fundoplexy |
| EP1956962B1 (de) | 2005-11-22 | 2020-09-16 | Intuitive Surgical Operations, Inc. | Systeme zur bestimmung der form eines biegbaren instruments |
| US8083879B2 (en) | 2005-11-23 | 2011-12-27 | Intuitive Surgical Operations, Inc. | Non-metallic, multi-strand control cable for steerable instruments |
| AU2007238753B2 (en) * | 2006-04-13 | 2013-04-04 | Cook Medical Technologies Llc | Apparatus and methods for endoscopic resection of tissue |
| US8568299B2 (en) | 2006-05-19 | 2013-10-29 | Intuitive Surgical Operations, Inc. | Methods and apparatus for displaying three-dimensional orientation of a steerable distal tip of an endoscope |
| US20070276491A1 (en) * | 2006-05-24 | 2007-11-29 | Disc Dynamics, Inc. | Mold assembly for intervertebral prosthesis |
| US8092536B2 (en) * | 2006-05-24 | 2012-01-10 | Disc Dynamics, Inc. | Retention structure for in situ formation of an intervertebral prosthesis |
| RU2313286C1 (ru) * | 2006-06-13 | 2007-12-27 | Государственное образовательное учреждение высшего профессионального образования Кировская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию (ГОУ ВПО Кировская ГМА Росздрава) | Способ профилактики несостоятельности панкреатоеюно- и гепатикоеюноанастомозов при панкреатодуоденальной резекции |
| US8066725B2 (en) | 2006-10-17 | 2011-11-29 | Ams Research Corporation | Anastomosis device having improved safety features |
| US7993264B2 (en) | 2006-11-09 | 2011-08-09 | Ams Research Corporation | Orientation adapter for injection tube in flexible endoscope |
| US8277466B2 (en) | 2006-11-14 | 2012-10-02 | Ams Research Corporation | Anastomosis device and method |
| US8491525B2 (en) | 2006-11-17 | 2013-07-23 | Ams Research Corporation | Systems, apparatus and associated methods for needleless delivery of therapeutic fluids |
| US10004507B2 (en) | 2007-06-18 | 2018-06-26 | Asfora Ip, Llc | Vascular anastomosis device and method |
| US8361092B1 (en) | 2007-06-18 | 2013-01-29 | Wilson T. Asfora | Vascular anastomosis device and method |
| US9504469B2 (en) | 2007-06-18 | 2016-11-29 | Asfora Ip, Llc | Vascular anastomosis device and method |
| US8858576B2 (en) * | 2007-09-10 | 2014-10-14 | Olympus Medical Systems Corp. | Tissue fastening tool, stent, applicator for placing the same, and tissue fastening method through natural orifice |
| US9220398B2 (en) | 2007-10-11 | 2015-12-29 | Intuitive Surgical Operations, Inc. | System for managing Bowden cables in articulating instruments |
| US7850649B2 (en) | 2007-11-09 | 2010-12-14 | Ams Research Corporation | Mechanical volume control for injection devices |
| US8182418B2 (en) | 2008-02-25 | 2012-05-22 | Intuitive Surgical Operations, Inc. | Systems and methods for articulating an elongate body |
| US20090281379A1 (en) | 2008-05-12 | 2009-11-12 | Xlumena, Inc. | System and method for transluminal access |
| US8454632B2 (en) | 2008-05-12 | 2013-06-04 | Xlumena, Inc. | Tissue anchor for securing tissue layers |
| US8388349B2 (en) | 2009-01-14 | 2013-03-05 | Ams Research Corporation | Anastomosis deployment force training tool |
| US9364259B2 (en) | 2009-04-21 | 2016-06-14 | Xlumena, Inc. | System and method for delivering expanding trocar through a sheath |
| EP2434961B1 (de) | 2009-05-29 | 2015-01-14 | Xlumena, Inc. | Vorrichtung und verfahren zum einsetzen eines stents in benachbarten gewebeschichten |
| ES2656939T3 (es) * | 2010-03-09 | 2018-03-01 | Solinas Medical Inc. | Dispositivos de cierre automático |
| US8747386B2 (en) | 2010-12-16 | 2014-06-10 | Ams Research Corporation | Anastomosis device and related methods |
| WO2012170364A1 (en) | 2011-06-10 | 2012-12-13 | Medtronic, Inc. | Wire electrode devices for tonsillectomy and adenoidectomy |
| US9381335B2 (en) | 2012-03-21 | 2016-07-05 | Ams Research Corporation | Bladder wall drug delivery system |
| WO2013173045A1 (en) | 2012-05-17 | 2013-11-21 | Xlumena, Inc. | Methods and devices for access across adjacent tissue layers |
| ES2980140T3 (es) | 2013-02-21 | 2024-09-30 | Boston Scient Scimed Inc | Dispositivos para formar una anastomosis |
| CN208927391U (zh) * | 2017-11-07 | 2019-06-04 | 南京鼓楼医院 | 用于胃肠吻合的双球囊导管装置 |
| JP2022090253A (ja) * | 2020-12-07 | 2022-06-17 | テルモ株式会社 | リンパ管新生誘導デバイス |
| KR102938364B1 (ko) | 2023-03-14 | 2026-03-11 | 충남대학교병원 | 담낭십이지장문합 동물모델 |
| CN117357185B (zh) * | 2023-11-20 | 2024-12-03 | 上海傲流医疗科技有限公司 | 经导管血管断开器及其对应的吻合器 |
| CN118285866B (zh) * | 2024-04-01 | 2024-11-05 | 中国人民解放军空军军医大学 | 一种血管内瘘成形术用血管支撑器 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4731055A (en) * | 1986-08-25 | 1988-03-15 | Becton, Dickinson And Company | Blood flow conduit |
| US5549122A (en) * | 1989-07-26 | 1996-08-27 | Detweilwer; Mark B. | Methods of surgical mammalian vessel anastomosis |
| US5749895A (en) * | 1991-02-13 | 1998-05-12 | Fusion Medical Technologies, Inc. | Method for bonding or fusion of biological tissue and material |
| US5385606A (en) | 1992-07-06 | 1995-01-31 | Kowanko; Nicholas | Adhesive composition and method |
| US5254113A (en) * | 1992-08-31 | 1993-10-19 | Wilk Peter J | Anastomosis method |
| US5725551A (en) * | 1993-07-26 | 1998-03-10 | Myers; Gene | Method and apparatus for arteriotomy closure |
| FR2726571B1 (fr) * | 1994-11-03 | 1997-08-08 | Izoret Georges | Colle biologique, procede de preparation et dispositif d'application pour colle biologique, et durcisseurs pour colle biologique |
| US5647380A (en) * | 1995-06-07 | 1997-07-15 | W. L. Gore & Associates, Inc. | Method of making a left ventricular assist device |
| US6068637A (en) | 1995-10-03 | 2000-05-30 | Cedar Sinai Medical Center | Method and devices for performing vascular anastomosis |
| US5702412A (en) * | 1995-10-03 | 1997-12-30 | Cedars-Sinai Medical Center | Method and devices for performing vascular anastomosis |
| AU7671196A (en) | 1995-11-07 | 1997-05-29 | Fusion Medical Technologies, Inc. | Methods and articles for fusing matrix layers containing non-collagenous proteins to tissue |
| ATE247429T1 (de) * | 1996-02-02 | 2003-09-15 | Transvascular Inc | System für interstitielle transvaskuläre chirurgische eingriffe |
| WO1997029715A1 (en) * | 1996-02-20 | 1997-08-21 | Fusion Medical Technologies, Inc. | Compositions and methods for sealing tissue and preventing post-surgical adhesions |
| US5868763A (en) * | 1996-09-16 | 1999-02-09 | Guidant Corporation | Means and methods for performing an anastomosis |
| US5728134A (en) * | 1996-09-17 | 1998-03-17 | Barak; Shlomo | Method and apparatus for hemostasis |
| US6026814A (en) * | 1997-03-06 | 2000-02-22 | Scimed Life Systems, Inc. | System and method for percutaneous coronary artery bypass |
-
1998
- 1998-09-25 EP EP05014269A patent/EP1584292B1/de not_active Expired - Lifetime
- 1998-09-25 AT AT05014269T patent/ATE520356T1/de active
- 1998-09-25 EP EP98951939A patent/EP1018944A4/de not_active Withdrawn
- 1998-09-25 KR KR1020007001847A patent/KR20010023218A/ko not_active Withdrawn
- 1998-09-25 ES ES05014269T patent/ES2368847T3/es not_active Expired - Lifetime
- 1998-09-25 AU AU97763/98A patent/AU748152C/en not_active Ceased
- 1998-09-25 JP JP2000513506A patent/JP4205306B2/ja not_active Expired - Fee Related
- 1998-09-25 WO PCT/US1998/020071 patent/WO1999016359A1/en not_active Ceased
- 1998-09-25 US US09/161,101 patent/US6685726B2/en not_active Expired - Fee Related
- 1998-09-25 CA CA002299407A patent/CA2299407C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20020138098A1 (en) | 2002-09-26 |
| ATE520356T1 (de) | 2011-09-15 |
| KR20010023218A (ko) | 2001-03-26 |
| AU748152B2 (en) | 2002-05-30 |
| US6685726B2 (en) | 2004-02-03 |
| EP1018944A1 (de) | 2000-07-19 |
| AU748152C (en) | 2004-03-25 |
| WO1999016359A9 (en) | 1999-07-15 |
| EP1584292B1 (de) | 2011-08-17 |
| WO1999016359A1 (en) | 1999-04-08 |
| JP2001517524A (ja) | 2001-10-09 |
| AU9776398A (en) | 1999-04-23 |
| EP1018944A4 (de) | 2001-08-22 |
| CA2299407A1 (en) | 1999-04-08 |
| ES2368847T3 (es) | 2011-11-22 |
| CA2299407C (en) | 2007-01-09 |
| EP1584292A1 (de) | 2005-10-12 |
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