JP4198195B2 - 負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用 - Google Patents

負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用 Download PDF

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JP4198195B2
JP4198195B2 JP54828198A JP54828198A JP4198195B2 JP 4198195 B2 JP4198195 B2 JP 4198195B2 JP 54828198 A JP54828198 A JP 54828198A JP 54828198 A JP54828198 A JP 54828198A JP 4198195 B2 JP4198195 B2 JP 4198195B2
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JP2001527409A (ja
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ワーツ,ゲイル
アンドリュー ボール,エル
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ザ ユーエイビー リサーチ ファンデイション
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    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
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    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20241Use of virus, viral particle or viral elements as a vector
    • C12N2760/20243Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2760/00011Details
    • C12N2760/20011Rhabdoviridae
    • C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261Methods of inactivation or attenuation

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  • Veterinary Medicine (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP54828198A 1997-05-02 1998-05-01 負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用 Expired - Fee Related JP4198195B2 (ja)

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US4547197P 1997-05-02 1997-05-02
US60/045,471 1997-05-02
PCT/US1998/008938 WO1998050529A1 (en) 1997-05-02 1998-05-01 Attenuation of negative stranded rna viruses by rearrangement of their genes and uses thereof

Related Child Applications (1)

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JP2007242099A Division JP2008022859A (ja) 1997-05-02 2007-09-19 遺伝子の再配列による(−)鎖rnaウイルスの弱毒化およびそれらの使用法

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JP2001527409A JP2001527409A (ja) 2001-12-25
JP2001527409A5 JP2001527409A5 (enExample) 2005-11-24
JP4198195B2 true JP4198195B2 (ja) 2008-12-17

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JP54828198A Expired - Fee Related JP4198195B2 (ja) 1997-05-02 1998-05-01 負鎖rnaウイルスの、それらの遺伝子の再配列による弱毒化およびそれらの使用
JP2007242099A Pending JP2008022859A (ja) 1997-05-02 2007-09-19 遺伝子の再配列による(−)鎖rnaウイルスの弱毒化およびそれらの使用法

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JP2007242099A Pending JP2008022859A (ja) 1997-05-02 2007-09-19 遺伝子の再配列による(−)鎖rnaウイルスの弱毒化およびそれらの使用法

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US (1) US6136585A (enExample)
EP (1) EP1005535B1 (enExample)
JP (2) JP4198195B2 (enExample)
AU (1) AU739597B2 (enExample)
CA (1) CA2288434C (enExample)
WO (1) WO1998050529A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136585A (en) * 1997-05-02 2000-10-24 Uab Research Foundation Attenuation of negative stranded RNA viruses by rearrangement of genes and uses thereof
US6596529B1 (en) * 1997-05-02 2003-07-22 Uab Research Foundation Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
US20030082209A1 (en) * 2000-07-05 2003-05-01 Skiadopoulos Mario H. Attenuated human-bovine chimeric parainfluenza virus (PIV) vaccines
EP1137759A2 (en) * 1998-12-07 2001-10-04 U.S. Medical Research Institute of Infectious Diseases Live attenuated venezuelan equine encephalitis vaccine
US6764685B1 (en) * 2000-03-21 2004-07-20 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines
CA2477037C (en) * 2002-02-21 2014-12-09 Mount Sinai School Of Medicine Recombinant negative strand virus rna expression systems and vaccines
CA2477235A1 (en) * 2002-02-21 2003-09-04 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus
KR100999316B1 (ko) 2003-06-09 2010-12-10 와이어쓰 엘엘씨 cDNA로부터의 비분절 네가티브 쇄 RNA 바이러스의회수를 위한 개선된 방법
US8287878B2 (en) * 2004-04-09 2012-10-16 Wyeth Llc Synergistic attenuation of vesicular stomatitis virus, vectors thereof and immunogenic compositions thereof
US8097419B2 (en) 2006-09-12 2012-01-17 Longhorn Vaccines & Diagnostics Llc Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009
US8652782B2 (en) 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US9481912B2 (en) 2006-09-12 2016-11-01 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
CN105769931B (zh) 2006-09-15 2021-04-27 渥太华医院研究机构 溶瘤弹状病毒
EP2069485A4 (en) * 2007-07-13 2011-05-25 Medimmune Llc PREPARATION OF NEGATIVE STRAND RNA VIRUSES BY ELECTROPORATION
US9683256B2 (en) 2007-10-01 2017-06-20 Longhorn Vaccines And Diagnostics, Llc Biological specimen collection and transport system
US11041215B2 (en) 2007-08-24 2021-06-22 Longhorn Vaccines And Diagnostics, Llc PCR ready compositions and methods for detecting and identifying nucleic acid sequences
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
EP3058954B1 (en) 2007-08-27 2017-03-01 Longhorn Vaccines and Diagnostics, LLC Immunogenic compositions and methods
US11041216B2 (en) 2007-10-01 2021-06-22 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples
ES2552858T3 (es) 2007-10-01 2015-12-02 Longhorn Vaccines And Diagnostics, Llc Recogida de muestras biológicas y sistema de transporte y métodos de uso
JP5045416B2 (ja) * 2007-12-17 2012-10-10 富士通株式会社 光導波路素子およびそれを用いた光学装置
US20090175900A1 (en) * 2007-12-20 2009-07-09 Wyeth Methods for packaging propagation-defective vesicular stomatitis virus vectors
US20090162321A1 (en) * 2007-12-20 2009-06-25 Wyeth Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein
EP3494989B1 (en) 2012-01-26 2025-07-16 Longhorn Vaccines and Diagnostics, LLC Composite antigenic sequences and vaccines
CA2985652C (en) 2015-05-14 2020-03-10 Gerald W. FISHER Rapid methods for the extraction of nucleic acids from biological samples
US12485166B2 (en) 2020-02-06 2025-12-02 Longhorn Vaccines And Diagnostics, Llc Vaccines for the treatment and prevention of zoonotic infections
GB2615470A (en) 2020-10-20 2023-08-09 Longhorn Vaccines & Diagnostics Llc Immunogenic antigens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2112220A3 (en) * 1996-07-15 2010-01-06 The Government of the United States of America, as represented by The Department of Health and Human Services Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences
US6136585A (en) * 1997-05-02 2000-10-24 Uab Research Foundation Attenuation of negative stranded RNA viruses by rearrangement of genes and uses thereof

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Publication number Publication date
CA2288434A1 (en) 1998-11-12
EP1005535A4 (en) 2002-07-17
JP2001527409A (ja) 2001-12-25
CA2288434C (en) 2012-01-03
JP2008022859A (ja) 2008-02-07
AU7278198A (en) 1998-11-27
EP1005535B1 (en) 2015-11-11
US6136585A (en) 2000-10-24
EP1005535A1 (en) 2000-06-07
WO1998050529A1 (en) 1998-11-12
AU739597B2 (en) 2001-10-18

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