JP4154460B2 - 抗潰瘍剤 - Google Patents
抗潰瘍剤 Download PDFInfo
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- JP4154460B2 JP4154460B2 JP2006303973A JP2006303973A JP4154460B2 JP 4154460 B2 JP4154460 B2 JP 4154460B2 JP 2006303973 A JP2006303973 A JP 2006303973A JP 2006303973 A JP2006303973 A JP 2006303973A JP 4154460 B2 JP4154460 B2 JP 4154460B2
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- solid solution
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Description
したがって本発明の目的は、胃酸とペプシンの攻撃を防ぎながら、同時に潰瘍面を修復できる多機能型抗潰瘍剤を提供することにある。
(但し、式中、M2+はMgまたはMgとCa、好ましくはMgを示し、M3+はAlを示し、An−はCO3 2−,SO4 2−,リンゴ酸、クエン酸、酒石酸、グリシン、β−アラニン等のn価のアニオン、好ましくはCO3 2−を示し、x,y,mおよびnはそれぞれ次の範囲を示す。0<x<0.5、好ましくは0.2≦x<0.4,0<y≦1、好ましくは0.05<y<0.5、0≦m<4、nは1以上の整数)で表されるZn固溶ハイドロタルサイト類、または下記式(2)
(Zn)0.67Al0.33(OH)2(CO3)0.165・0.5H2O
[(Zn)1.17Mg0.83]0.75Al0.25(OH)2(CO3)0.125・0.5H2O
制酸反応試験結果を表1に示す。
Mg0.95Zn0.05(OH)2
この粉末の制酸活性及びZnイオンの放出性能評価結果を表1に示す。
市販の酸化亜鉛(亜鉛華1号)を用いて評価した結果を表1に示す。
代表的な制酸剤であるハイドロタルサイト;Mg0.75Al0.25(OH)2(CO3)0.125・0.5H2O、を用いて評価した結果を表1に示す。但し、用いたハイドロタルサイトは、実施例2において、金属塩水溶液として塩化マグネシウムと硝酸アルミニウム(Mg=1.2モル/リットル,Al=0.4モル/リットル)を用いる以外は同様にして行った。
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006303973A JP4154460B2 (ja) | 2006-11-09 | 2006-11-09 | 抗潰瘍剤 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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JP2006303973A JP4154460B2 (ja) | 2006-11-09 | 2006-11-09 | 抗潰瘍剤 |
Publications (2)
Publication Number | Publication Date |
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JP2008120703A JP2008120703A (ja) | 2008-05-29 |
JP4154460B2 true JP4154460B2 (ja) | 2008-09-24 |
Family
ID=39505848
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2006303973A Expired - Fee Related JP4154460B2 (ja) | 2006-11-09 | 2006-11-09 | 抗潰瘍剤 |
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JP (1) | JP4154460B2 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101365463B (zh) | 2006-12-20 | 2010-12-08 | 协和化学工业株式会社 | 抗酸剂 |
CN101835478B (zh) * | 2007-10-29 | 2012-12-26 | 协和化学工业株式会社 | 缓泻剂 |
TWI444190B (zh) | 2007-12-10 | 2014-07-11 | Kyowa Chem Ind Co Ltd | 潰瘍治療劑 |
JP2009263294A (ja) * | 2008-04-28 | 2009-11-12 | Kyowa Chem Ind Co Ltd | 潰瘍抑制・治療剤 |
WO2010098417A1 (ja) * | 2009-02-25 | 2010-09-02 | 協和化学工業株式会社 | 酸化マグネシウム細粒 |
JP2010265207A (ja) * | 2009-05-14 | 2010-11-25 | Kyowa Chem Ind Co Ltd | 膵臓機能強化乃至活性化用複合ハイドロタルサイト粒子 |
JP2010265208A (ja) * | 2009-05-14 | 2010-11-25 | Kyowa Chem Ind Co Ltd | 膵臓機能強化乃至活性化用複合酸化マグネシウム粒子 |
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2006
- 2006-11-09 JP JP2006303973A patent/JP4154460B2/ja not_active Expired - Fee Related
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JP2008120703A (ja) | 2008-05-29 |
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