JP4061039B2 - 微小透析システム - Google Patents

微小透析システム Download PDF

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Publication number
JP4061039B2
JP4061039B2 JP2001229622A JP2001229622A JP4061039B2 JP 4061039 B2 JP4061039 B2 JP 4061039B2 JP 2001229622 A JP2001229622 A JP 2001229622A JP 2001229622 A JP2001229622 A JP 2001229622A JP 4061039 B2 JP4061039 B2 JP 4061039B2
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JP
Japan
Prior art keywords
probe
microdialysis
pump unit
perfusate
suction
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JP2001229622A
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Japanese (ja)
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JP2002126074A5 (https=
JP2002126074A (ja
Inventor
レーパー ヨーゼフ
シェーマーカー ミハエル
ヘラウフ クリスチャン
Original Assignee
エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト
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Publication of JP2002126074A5 publication Critical patent/JP2002126074A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14525Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using microdialysis
    • A61B5/14528Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using microdialysis invasively
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • External Artificial Organs (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Centrifugal Separators (AREA)
JP2001229622A 2000-08-04 2001-07-30 微小透析システム Expired - Fee Related JP4061039B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10038835A DE10038835B4 (de) 2000-08-04 2000-08-04 Mikrodialyseanordnung
DE10038835.3 2000-08-04

Publications (3)

Publication Number Publication Date
JP2002126074A JP2002126074A (ja) 2002-05-08
JP2002126074A5 JP2002126074A5 (https=) 2005-05-12
JP4061039B2 true JP4061039B2 (ja) 2008-03-12

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ID=7651829

Family Applications (1)

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JP2001229622A Expired - Fee Related JP4061039B2 (ja) 2000-08-04 2001-07-30 微小透析システム

Country Status (6)

Country Link
US (1) US6591126B2 (https=)
EP (1) EP1177759B1 (https=)
JP (1) JP4061039B2 (https=)
AT (1) ATE279877T1 (https=)
DE (2) DE10038835B4 (https=)
ES (1) ES2230215T3 (https=)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
DE19935165A1 (de) * 1999-07-28 2001-02-01 Roche Diagnostics Gmbh Verfahren und Anordnung zur Konzentrationsbestimmung von Glucose in einer Körperflüssigkeit
US7769420B2 (en) 2000-05-15 2010-08-03 Silver James H Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
EP1397068A2 (en) 2001-04-02 2004-03-17 Therasense, Inc. Blood glucose tracking apparatus and methods
US20030143746A1 (en) * 2002-01-31 2003-07-31 Sage Burton H. Self-calibrating body anayte monitoring system
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US7415299B2 (en) * 2003-04-18 2008-08-19 The Regents Of The University Of California Monitoring method and/or apparatus
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
GB0313755D0 (en) * 2003-06-13 2003-07-23 Isis Innovation Monitoring method
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US8165651B2 (en) * 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
WO2005089103A2 (en) 2004-02-17 2005-09-29 Therasense, Inc. Method and system for providing data communication in continuous glucose monitoring and management system
SE527196C2 (sv) * 2004-07-08 2006-01-17 Chemel Ab SIRE genomflödesdetektor
ATE414465T1 (de) * 2004-08-19 2008-12-15 Danfoss As Vorrichtung zur durchführung von mikroanalysen
WO2006105146A2 (en) * 2005-03-29 2006-10-05 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
EP1759725A1 (fr) * 2005-08-31 2007-03-07 Université Libre De Bruxelles Sonde electro-biochimique d'analyse intramusculaire ou intracerebrale
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
US20100049021A1 (en) * 2006-03-28 2010-02-25 Jina Arvind N Devices, systems, methods and tools for continuous analyte monitoring
US20080154107A1 (en) * 2006-12-20 2008-06-26 Jina Arvind N Device, systems, methods and tools for continuous glucose monitoring
US20090131778A1 (en) * 2006-03-28 2009-05-21 Jina Arvind N Devices, systems, methods and tools for continuous glucose monitoring
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
EP1857134A1 (en) * 2006-05-15 2007-11-21 JOANNEUM RESEARCH Forschungsgesellschaft mbH Catheter having an oblong slit
US7920907B2 (en) 2006-06-07 2011-04-05 Abbott Diabetes Care Inc. Analyte monitoring system and method
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
EP2079828A4 (en) * 2006-11-09 2010-03-10 Sense Ltd G SYSTEM AND METHOD FOR PSEUDO-CONTINUOUS MEASUREMENT OF METABOLITE CONCENTRATIONS IN A MAMMALIAN BODY
WO2008089282A2 (en) 2007-01-16 2008-07-24 Silver James H Sensors for detecting subtances indicative of stroke, ischemia, infection or inflammation
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US7751864B2 (en) 2007-03-01 2010-07-06 Roche Diagnostics Operations, Inc. System and method for operating an electrochemical analyte sensor
US20080234562A1 (en) * 2007-03-19 2008-09-25 Jina Arvind N Continuous analyte monitor with multi-point self-calibration
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20080312518A1 (en) * 2007-06-14 2008-12-18 Arkal Medical, Inc On-demand analyte monitor and method of use
US20090044604A1 (en) * 2007-08-15 2009-02-19 Gregor Ocvirk Portable Measuring Facility for Determining A Medically Significant Analyte Concentration
US20090099427A1 (en) * 2007-10-12 2009-04-16 Arkal Medical, Inc. Microneedle array with diverse needle configurations
US20090105562A1 (en) * 2007-10-19 2009-04-23 Taipei Veterans General Hospital System and methods for screening or analyzing targets
EP2515109A3 (en) 2007-10-29 2012-11-14 Taipei Veterans General Hospital System and methods for screening or analyzing targets
US9101304B2 (en) * 2008-07-02 2015-08-11 Maquet Critical Care Ab On-line measuring system of body substances
US20100179397A1 (en) * 2009-01-09 2010-07-15 Bright Frank V Device And Method For Continuous Monitoring Of A Chemical Parameter Of An Individual
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
WO2010118150A1 (en) * 2009-04-07 2010-10-14 Carnegie Mellon University Real-time microdialysis system
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
EP2473098A4 (en) 2009-08-31 2014-04-09 Abbott Diabetes Care Inc ANALYTICAL SIGNAL PROCESSING APPARATUS AND METHOD
US8993331B2 (en) 2009-08-31 2015-03-31 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9320461B2 (en) 2009-09-29 2016-04-26 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
EP2688602B1 (en) 2011-03-23 2019-11-06 NxStage Medical, Inc. Peritoneal dialysis systems, devices, and methods
US9861733B2 (en) 2012-03-23 2018-01-09 Nxstage Medical Inc. Peritoneal dialysis systems, devices, and methods
EP3677182B1 (en) 2011-11-07 2022-05-04 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
EP2719407A1 (en) * 2012-10-09 2014-04-16 EU Sol Biotech Co., Ltd. Kit for treating brain injury or stroke
DE102013104501A1 (de) * 2013-05-02 2014-11-06 B. Braun Avitum Ag Vorrichtung zur extrakorporalen Blutbehandlung
US11229382B2 (en) 2013-12-31 2022-01-25 Abbott Diabetes Care Inc. Self-powered analyte sensor and devices using the same
SE539230C2 (en) 2015-09-04 2017-05-23 Senzime Ab (Publ ) Microdialysis device comprising attachment sheet
WO2017174557A2 (en) * 2016-04-04 2017-10-12 Brains Online Holding B.V. Use of push pull microdialysis in combination with shotgun proteomics for analyzing the proteome in extracellular space of brain
WO2018237375A1 (en) 2017-06-24 2018-12-27 Nxstage Medical, Inc. Peritoneal dialysis fluid preparation and/or treatment devices methods and systems
EP3441741A1 (de) * 2017-08-11 2019-02-13 Metrohm Ag Dialysezelle zur probenvorbereitung für ein chemisches analyseverfahren
US20190262526A1 (en) 2018-02-28 2019-08-29 Nxstage Medical, Inc. Fluid Preparation and Treatment Devices Methods and Systems
CN112972803B (zh) * 2021-04-22 2021-08-10 上海花涯自动化科技有限公司 一种包括流量反馈装置的微透析系统

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1460954A (fr) * 1964-11-30 1966-01-07 Beckman Instruments Inc Perfectionnements à l'analyse du sang
AT391998B (de) * 1987-02-02 1990-12-27 Falko Dr Skrabal Vorrichtung zur bestimmung der konzentration zumindest einer medizinischen substanz in lebenden organismen
ATE97791T1 (de) * 1988-10-31 1993-12-15 Avl Medical Instr Ag Vorrichtung zur bestimmung der konzentration von zumindest einer in organischem gewebe vorliegenden substanz.
DE4401400A1 (de) 1994-01-19 1995-07-20 Ernst Prof Dr Pfeiffer Verfahren und Anordnung zur kontinuierlichen Überwachung der Konzentration eines Metaboliten
DE4426694C2 (de) * 1994-07-28 1998-07-23 Boehringer Mannheim Gmbh Vorrichtung zur Langzeitbestimmung des Gehaltes von mindestens einer Substanz in Körperflüssigkeiten
DE19618597B4 (de) * 1996-05-09 2005-07-21 Institut für Diabetestechnologie Gemeinnützige Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm Verfahren zur Bestimmung der Konzentration von Gewebeglucose
SE9800693D0 (sv) * 1998-03-05 1998-03-05 Siemens Elema Ab A monitor for diffusable chemical substances
JP3372862B2 (ja) * 1998-03-25 2003-02-04 株式会社日立製作所 生体液の質量分析装置

Also Published As

Publication number Publication date
ATE279877T1 (de) 2004-11-15
DE50104184D1 (de) 2004-11-25
DE10038835A1 (de) 2002-02-28
DE10038835B4 (de) 2005-07-07
US6591126B2 (en) 2003-07-08
EP1177759B1 (de) 2004-10-20
US20020082490A1 (en) 2002-06-27
JP2002126074A (ja) 2002-05-08
EP1177759A1 (de) 2002-02-06
ES2230215T3 (es) 2005-05-01

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