JP3804504B2 - Container and its inspection method - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to a container to which a plurality of small containers are connected and an inspection method thereof.
[0002]
[Prior art]
As an example of a two-chamber type infusion container, there is a container having a small medicine container in which a powdery medicine is accommodated in a storage chamber and a small medicine container in which a liquid chemical solution is accommodated in a storage chamber. . In this case, a pair of connecting piece portions opposed to each other are provided at the lower end portion of the small drug container, and the upper end portion of the small drug solution container is inserted and welded between the connecting piece portions. Both small containers are connected. Further, both the storage chambers are partitioned by the partition portions, and the partition portions are damaged, so that the medicine and the chemical solution in each storage chamber are mixed.
By the way, in the past, it was visually inspected whether or not the upper end of the small container for chemical solution was inserted between the connecting pieces.
[0003]
[Problems to be solved by the invention]
However, this visual inspection is not easy, and there is a demand for improvement thereof, and there has also been a demand for enabling inspection by an inspection apparatus instead of visual inspection.
[0004]
An object of this invention is to provide the container which can solve the said problem, and its inspection method.
[0005]
[Means for Solving the Problems]
In order to achieve the above object, the container of the present invention is characterized by having a small container for storing a solid substance in a storage chamber and a small container for storing a liquid substance in a storage chamber. A pair of opposing connection piece portions are provided at the end portions of the other container, and the end portions of the other small container are inserted and welded between the connection piece portions, and the two storage chambers are partitioned by the partition portions. by damaging the in container for mixing both housing chamber substances, together with one connection piece is transparent, the connecting pieces of this, the printing unit visible is formed from the outside, the other connection The point is that one part is opaque.
In addition, a connection piece part is formed by laminating a plurality of layers, and a printed part may be formed on a surface of these layers other than the surfaces corresponding to the inner and outer surfaces of the connection piece part.
In addition, the printing portion may be formed in a solid state over the entire surface of the connection piece portion. Further, the container inspection method according to the present invention is characterized in that, at the time of manufacturing the container, after the end portion of the small container is inserted between the connection piece portions, light is emitted to the connection piece portion on which the printing portion is formed. Irradiation, the reflected light is detected by a detector, and the insertion state is inspected from the detection result.
In addition, light may be irradiated to several places regarding the width direction of a connection piece part.
[0006]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, an example of an embodiment in which the present invention is applied to a multi-chamber (two-chamber) container-type infusion container that is a medical container will be described with reference to the drawings. FIG. 1 shows a flexible substantially flat infusion container. The container has an upper flexible first small container (small drug container) 1 and a lower flexible second small container (small liquid drug container) 2.
[0007]
As shown also in FIG. 2, the 1st small container 1 is made into the substantially rectangular shape which is a little flat and slightly long up and down, the front seat 4 which comprises the front wall, the rear seat 5 which comprises the back wall, and a division A part forming sheet 6 and a cover sheet 7 are provided.
[0008]
The first small container 1 is manufactured as follows. That is, as shown in FIG. 3A, the front seat 4 and the rear seat 5 are overlapped in the front-rear direction, and the partition forming sheet 6 is placed between the upper portions of the seats 4 and 5 slightly above the lower ends. As shown in FIG. 3 (B), the portions of the left and right sides of the front seat 4 and the rear seat 5 other than the lower end are heat-welded 9 so as not to be peeled off. Further, the front seat 4 and the rear seat 5 are weakly welded to the lower end portion of the partition portion forming sheet 6 to form a partition portion (weak seal portion) 10, and the front seat 4 and The rear sheet 5 is heat-welded 11 so that it cannot be peeled off.
[0009]
Thereby, the upper side of the seats 4 and 5 is formed into a bag shape that opens upward, and the lower end portion is a pair of connecting piece portions 13A and 13B that are opposed to each other in the front-rear direction. Open downward. After sterilizing this with radiation, EOG, etc., the bag-shaped portion is filled with a medicine, and as shown in FIG. 3C, the front seat 4 and the upper portion of the rear seat 5 are heat-welded 14 so as not to be peeled off. The first storage chamber 15 filled with and containing a medicine is formed between the sheets 4 and 5. The cover sheet 7 is detachably bonded to the front sheet 6 after connecting both small containers, and the cover sheet 7 covers the front wall of the first storage chamber 15. In addition, the said adhesion | attachment of the cover sheet 7 is performed by heat welding or the crimping | compression-bonding by an adhesive or an adhesive agent.
[0010]
The front sheet 4 is a transparent flexible sheet that hardly allows moisture and gas (oxygen) to pass through. A laminate sheet (film) including a polyethylene (terephthalate) layer deposited on silica (SiO ₂ ) is suitable. In this example, as shown in FIG. 4, as the front sheet 4, the outermost layer 4A is a polyethylene (PE) layer, the intermediate layer 4B is a polyethylene terephthalate layer in which silica is deposited on the front side (rear side), A PE / silica vapor-deposited PET / PE configuration or the like in which the innermost layer 4C is a polyethylene layer is employed. The outermost layer 4A may be a polyethylene / polypropylene copolymer layer.
[0011]
And in the connection piece part 13A of the front seat 4, any one of the surfaces excluding the front surface (outer surface) and the rear surface (inner surface) of the connection piece part 13A among the surfaces of the three layers 4A to 4C, in other words, the outermost layer A printed portion (cross-hatched portion in FIGS. 1 and 3) 21 that is printed on any one of the rear surface of 4A, the front surface or the rear surface of the intermediate layer 4B, or the front surface of the innermost layer 4C and visible from the outside. Is formed. In some cases, the printing portion 21 may be formed on the front surface or the rear surface of the connection piece portion 13A, in other words, on the front surface of the outermost layer 4A or the rear surface of the innermost layer 4C. Further, in this example, the printing unit 21 is formed on any one of the above surfaces in a solid coating state (not necessarily solid coating). The color of the printing unit 21 is usually a chromatic color such as red or orange, but may be an achromatic color such as black or gray.
[0012]
The rear sheet 5 and the cover sheet 7 are opaque flexible sheets having moisture impermeability, gas (oxygen) impermeability, and light shielding properties, and an aluminum foil laminate sheet (film) is preferable. For example, as the sheets 5 and 7, a PET / aluminum foil / PE configuration in which the outermost layer is a polyethylene terephthalate layer and the innermost layer is a polyethylene layer is employed. The aluminum foil has moisture impermeability, gas impermeability, and light shielding properties, but other metal foils having the above characteristics can be used instead of the aluminum foil. Moreover, another resin layer may be interposed between the aluminum foil and polyethylene.
[0013]
The partition portion forming sheet 6 is transparent, and a resin having a low welding strength (weak welding) with polyethylene which is a constituent resin of the innermost layer of the front sheet 4 and the rear sheet 5 is employed as the constituent resin. For example, as the sheet 6, a polymer blend of polyethylene and a resin (for example, polypropylene) that is not compatible with this is suitably employed, and when polypropylene is employed as the resin that is not compatible, the polyethylene and polypropylene are used. The mixing ratio is preferably 3: 7 to 7: 3.
In addition, as a chemical | medical agent accommodated in the 1st storage chamber 15, solid chemical | medical agents, such as antibiotics, are normally used. The solid drug includes powder and tablet type drugs.
[0014]
The second small container 2 is substantially flat and has a substantially rectangular shape that is slightly longer in the vertical direction, a cylindrical transparent tube 23 that constitutes substantially the whole, a transparent partition portion forming sheet 24, and a connection It has a port 25 and a plug 26. The tube 23 is made of polyethylene or polypropylene, and a sheet similar to the partition part forming sheet 6 is used as the partition part forming sheet 24.
[0015]
The second small container 2 is manufactured as follows. That is, as shown in FIG. 5A, the partition portion forming sheet 24 is inserted into the upper end portion of the tube 23 having an upper and lower opening, and the tube 23 and the partition portion are formed as shown in FIG. The sheet 24 is weakly heat-welded to form a partition portion (weak seal portion) 28, and the front and rear wall portions of the tube 23 are heat-welded 29 so as not to be peeled off on both left and right sides thereof. Next, as shown in FIG. 5C, the connection port 25 is inserted into the lower end portion of the tube 23, and these are heat-welded 30 so as not to be peeled off. As shown in FIG. The remaining opening at the lower end of 23 is heat-welded 31 so as not to be peeled off, thereby forming the second storage chamber 32 in the tube 23. Next, after the cleaning liquid is injected into the second storage chamber 32 from the connection port 25, the inside of the second storage chamber 32 is cleaned and dried, and then the chemical solution is filled and stored in the second storage chamber 32 from the connection port 25. After that, the connection port 25 is closed by the plug 26. Then, the second small container 2 is sterilized with high-pressure steam.
[0016]
In addition, as a chemical | medical solution accommodated in the 2nd storage chamber 32, chemical | medical solutions, such as a normal solution, a solution for dissolving and diluting a physiological saline solution, antibiotics, and a sugar / electrolyte solution, are usually used.
[0017]
Next, the connection between the small containers 1 and 2 will be described. As shown in FIG. 6, the connection piece portions 13A and 13B of the first small container 1 are largely opened downward to form the connection piece portions 13A and 13A. 13B, the upper end portion of the second small container, that is, the upper end portion of the tube 23 and the partition portion forming sheet 24 is inserted from below, these are thermally welded, and both small containers 1 and 2 are connected and integrated. To do. Thereafter, the cover sheet 7 is bonded to the first small container 1.
[0018]
By the way, in this example, before bonding the cover sheet 7 (or after the cover sheet 7 is bonded), the connecting portions of the small containers 1 and 2 are inspected visually or by an inspection device from the front side. In the case of visual inspection, the upper end of the second small container 2 is not inserted well between the connection pieces 13A and 13B of the first small container 1, for example, the upper end of the second small container 2 is connected to the front side. Since the printing part 21 of the front connection piece parts 13A and 13B is visually recognized through the transparent upper end part of the second small container 2 when it is positioned in front of the piece part 13A, the second small It can be easily seen that the container 2 is not inserted well.
[0019]
Contrary to the above, when the upper end portion of the second small container 2 is positioned on the rear side of the rear connection piece portion 13B, the rear connection piece portion 13B is opaque. The upper end portion is not visible, and it can be easily understood that the second small container 2 is not inserted well in this case. Further, even when a part of each connection piece 13A, 13B is folded on another part when the second small container 2 is inserted, a part of each connection piece 13A, 13B cannot be seen. Therefore, also in this case, it can be easily understood that the second small container 2 is not inserted well.
[0020]
Moreover, when performing the insertion state of a 2nd small container with an inspection apparatus, the inspection apparatus shown in FIG. 2 is used. This inspection apparatus includes three detectors 34 each having a light emitting unit 34A and a light receiving unit 34B, and a control device 36 to which these detectors 34 are connected. The light receiving unit 34B is composed of a color sensor or the like, and has a diameter of, for example, 1.0 mm. At the time of the inspection, as shown by the phantom line in FIG. 3C, the light emitting portion 34A of each detector 34 causes the upper end portion of the center portion in the width direction of the front connection piece portion 13A of the first small container 1 and the width direction. Light is radiated from the front to three locations at the lower end of the both ends (which may be 1 or 2 locations, or 4 locations or more in the width direction), and each reflected light is irradiated to each detector 34. The light receiving unit 34B detects the color and intensity of the reflected light.
[0021]
Then, the control device 36 compares the detected value with a reference value (detected value when the insertion is performed satisfactorily). If the two values are different, the control device 36, for example, detects an abnormal lamp. Or a container in which an abnormal detection value is detected is excluded from the production line as a defective product. As described above, at the time of inspection by the inspection device, as in the case of visual inspection, was the upper end of the second small container 2 inserted between the connection pieces 13A and 13B of the first small container satisfactorily? , Can be easily detected.
[0022]
The infusion using the above infusion container is performed as follows. That is, first, after the cover sheet 7 is peeled from the first small container 1, the second storage chamber 32 is pressed, the partition portions 10 and 28 are peeled, and the first and second storage chambers 15 and 32 are communicated. . Thereafter, the storage chambers 15 and 32 are alternately pressed to mix the medicine in the first storage chamber 15 and the chemical solution in the second storage chamber 32. Next, the infusion set is connected to the connection port 25 of the container and instilled into the patient.
[0023]
In the above embodiment, the printing part is formed only on one of the pair of connection pieces, but the printing part may be formed on the other. In the embodiment, the partition portion is configured by heat welding. However, the partition portion may be configured by a so-called “folded bar” or the like that is communicated by breakage of the rod. Furthermore, in the embodiment, the present invention is applied to a medical container, and a medicine or a chemical solution is stored in a storage chamber. However, the present invention can also be applied to a container such as food, for example, one small container. It is also possible to store coffee powder, milk powder or the like in the storage chamber, store water in the storage chamber of the other small container, and mix water, coffee powder, milk powder or the like at the time of use. In the above embodiment, two small containers are used, but the present invention can be applied to a container having three or more small containers.
[0024]
【The invention's effect】
As described above in detail, according to the present invention, it can be easily inspected by visual inspection or an inspection device whether or not the small container has been successfully inserted between the connecting pieces.
Further, as described in claim 5, if light is applied to a plurality of locations in the width direction of the connection piece portion, even if a part of the connection piece portion is folded on another portion, this is performed by an inspection device. It can be easily detected.
[Brief description of the drawings]
FIG. 1 is a front view showing an example of an embodiment of the present invention.
FIG. 2 is a cross-sectional view taken along line AA in FIG.
FIG. 3 is an explanatory view showing a method for manufacturing the first small container in FIG. 1;
4 is a cross-sectional view of the front seat in FIG. 1. FIG.
FIG. 5 is an explanatory view showing a method for manufacturing the second small container in FIG. 1;
6 is a cross-sectional view showing a method for connecting both small containers in FIG. 1. FIG.
[Explanation of symbols]
DESCRIPTION OF SYMBOLS 1 1st small container 2 2nd small container 4 Front sheet | seat 4A-4C Layer 5 Rear sheet | seats 10 and 28 Partition part 13A, 13B Connection piece part 15 1st storage chamber 21 Printing part 32 2nd storage chamber 34 Detector 36 Control apparatus

Claims (5)

A small container for storing the solid substance in the storage chamber and a small container for storing the liquid substance in the storage chamber, and a pair of opposing connection piece portions are provided at one end of both small containers; In the container that mixes the substances in the two storage chambers by inserting the ends of the other small container between the two parts, welding, and partitioning both the storage chambers by the partition, and damaging the partition,
While one connecting piece is transparent,
The connecting pieces of this, the printing unit visible is formed from the outside,
A container in which the other connecting piece is opaque. The container according to claim 1, wherein the connection piece is formed by laminating a plurality of layers, and a printed portion is formed on a surface of each of the layers excluding a surface corresponding to an inner surface and an outer surface of the connection piece. The container according to claim 1, wherein the printing portion is formed in a solid state over the entire surface of the connection piece portion. At the time of manufacturing the container according to any one of claims 1 to 3, after the end of the small container is inserted between the connection pieces, the connection piece formed with the printing portion is irradiated with light and reflected. A container inspection method in which light is detected by a detector and the insertion state is inspected from the detection result. The container inspection method according to claim 4, wherein light is irradiated to a plurality of locations in the width direction of the connection piece.

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