JP3751630B2 - Cosmetics and method for producing the same - Google Patents

Description

  The present invention relates to a cosmetic comprising an extract of larch and a method for producing the same.

  Examples of plant-derived moisturizing ingredients include beans, oils and fats obtained from rice bran, polyglutamic acid obtained from extracts containing ceramide and natto.

  In addition, a cosmetic (LaraCare: trade name) containing arabinogalactan as a water-holding component is manufactured and sold by Lalex (USA). This cosmetic contains arabinogalactan extracted from North American Larch trees as an active ingredient (see http://www.larex.com/htm/laracare.html).

Furthermore, a cosmetic composition that can contain lignin and arabinogalactan as a polysaccharide component in addition to an acrylic terpolymer is known (see Patent Document 1).
JP 2000-7539 A

  In the case of producing cosmetics using plants as raw materials, reduction of production costs has become an extremely important issue. In the conventional production method described above, a substance extracted from a plant, for example, flavonoids such as catechin and taxifolin is isolated from raw materials, and this is polymerized with a basic substance. According to such a production method, it is necessary to go through a great number of production steps such as extraction, isolation and purification of flavonoids, polymerization step of flavonoids, and weighing and drying in the meantime. For this reason, the manufacturing process becomes extremely complicated. Therefore, the manufacturing cost has risen, and it has been difficult to compete in terms of price even if the performance is equivalent to that of a chemically synthesized product.

  Moreover, when it is desired to provide a cosmetic product as a final product with a plurality of functionalities, it is necessary to include a plurality of types of functional substances having a target function in the cosmetic as described in Patent Document 1 described above.

  And conventionally, it has been difficult to obtain a cosmetic containing a large amount of a plurality of active ingredients. Accordingly, it is expensive to include a plurality of active ingredients in the cosmetic at a predetermined concentration. As a result, the price of the cosmetic itself increases.

  Accordingly, an object of the present invention is to provide a cosmetic having both excellent moisture retention and antioxidant properties and excellent color tone. Another object of the present invention is to provide a cosmetic having a plurality of useful functions at a low cost. Furthermore, an object of the present invention is to provide a cosmetic production method capable of extracting a plurality of target active ingredients simultaneously and in a large amount by a very simple process, and enabling a significant reduction in production cost. .

  In order to solve the above-mentioned problems, the inventors of the present application have made extensive studies focusing on the genus Larix, which has abundant resources. As a result, it has been found that an extract extracted and processed from larch under specific conditions has extremely excellent properties as a cosmetic, and the present invention has been completed.

  That is, the cosmetic of the present invention contains water-soluble lignin, arabinogalactan, and polymerized taxifolin. The cosmetic of the present invention may contain other additional components as long as the object of the present invention is not impaired.

The cosmetic of the present invention is obtained by treating a larch ground product with a basic aqueous solution having a concentration of an aqueous solution of sodium hydroxide or potassium hydroxide of 0.025 mol / l or more and 0.25 mol / l or less . The extracted solution obtained by filtering the solution is allowed to stand for 24 to 168 hours in an environment of 0 ° C. to 50 ° C. to promote the self-polymerization of the extracted taxifolin, and the extracted extract solution is dried. it is especially good Ri obtained Rukoto a solid of cosmetics containing water-soluble lignin, arabinogalactan, and polymerized taxifolin.
The cosmetic of the present invention is made from a larch ground material. As the pulverized product of larch, a pulverized product of xylem or a mixture of pulverized product of xylem and bark is preferably used.

  The cosmetic of the present invention described above contains 30% to 60% by weight of water-soluble lignin, 30% to 60% by weight of arabinogalactan, and 10% to 20% by weight of taxiphorin polymer. Is preferred.

  The cosmetic of the present invention preferably has a color tone defined by an absorbance at a wavelength of 500 nm of 0.500 or more (after correction: described later) in a 0.1% by weight aqueous solution. At this time, the absorbance at a wavelength of 475 nm under the same conditions is preferably 0.500 or more (after correction: described later).

  In addition, when the cosmetic of the present invention described above is contained in cosmetics, the content is preferably 0.01% by weight to 1.0% by weight.

  The cosmetic production method of the present invention mainly includes the following steps.

That is, the larch pulverized product is treated with a basic aqueous solution having a sodium hydroxide or potassium hydroxide concentration of 0.025 mol / l or more and 0.25 mol / l or less, and the pulverized product is filtered to obtain an extraction solution. . Subsequently, this extraction solution is allowed to stand for 24 to 168 hours in an environment of 0 ° C. to 50 ° C. to promote self-polymerization of extracted taxifolin. The extract solution that has been allowed to stand is dried to obtain a solid cosmetic containing water-soluble lignin, arabinogalactan, and polymerized taxifolin .

  Moreover, the method for producing a cosmetic of the present invention comprises a step of treating a larch ground product with a basic aqueous solution to obtain an extraction solution, and the extraction solution in an environment of 45 ° C. to 85 ° C. It includes a step of standing for a time until the concentration of the active ingredient is at least five times concentrated, and a step of obtaining a solid cosmetic by drying the extraction solution that has been left standing.

  In addition, the environment of 45 degreeC to 85 degreeC here means the environment heated by heating means, such as a thermostat and a thermostat.

  This standing step is a step in which the extraction solution is preferably left in an environment of 55 ° C. to 70 ° C. for a period of time until the concentration of the active ingredient in the extraction solution is concentrated at least 5 times. It is good.

  The step of standing still is more preferably a step of leaving still for 5 hours in a reduced pressure environment at 55 ° C. or for 3 hours in a reduced pressure environment at 70 ° C.

  In this way, if left standing while heating, the extraction solution is concentrated and the polymerization of taxifolin, which is the active ingredient, is promoted.

In the manufacturing method of the above-mentioned cosmetics, Larch pulverized material pulverized xylem, or better to a mixture of pulverized and pulverized tree bark portions.

  If it is set as the structure mentioned above, it has the outstanding moisture retention and antioxidant property, and can provide the cosmetics excellent in the color tone.

  Moreover, if it is set as the manufacturing process and conditions as mentioned above, the cosmetics containing a lot of active ingredients can be manufactured by a simple process.

  Moreover, if the larch which is a tree which exists naturally abundantly and is not used effectively is used as a raw material, effective utilization of resources can be achieved.

  Hereinafter, embodiments of the present invention will be described. In the following description, specific materials, conditions, numerical conditions, and the like may be used. However, these are only preferred examples, and the present invention is not limited to these preferred examples.

  In the cosmetic of the present invention, the active ingredient responsible for antibacterial activity and antioxidant activity is water-soluble lignin.

  Lignin is one of the main components of wood and is strongly bonded to cellulose. That is, lignin is a substance that forms the main part of the wood skeleton. In order to remove (extract) lignin from the wood skeleton, it is necessary to immerse it in a very strong basic aqueous solution, for example, as used in the process of producing pulp.

  However, a relatively small lignin having a molecular weight of about 500 to 50,000 can be easily extracted with a basic solution having a low concentration of, for example, 0.25 mol / l or less, such as an aqueous sodium hydroxide solution. The lignin extracted as described above or a glycoside thereof and a mixture thereof are referred to as water-soluble lignin or low-molecular lignin.

  In the cosmetic of the present invention, the active ingredients responsible for moisture retention are polymerized flavonoids, specifically, for example, polymerized taxifolin and arabinogalactan.

  Taxifolin is a kind of plant polyphenol and is a flavonanol compound having a molecular weight of 304.3. Taxifolin is abundant in larch, especially in the xylem. This taxifolin is oxidatively self-polymerized by alkali treatment with an aqueous sodium hydroxide solution or the like. That is, “polymerized taxifolin” in this specification refers to a polymer in which taxifolin molecules are oxidatively self-polymerized.

  Arabinogalactan refers to a polysaccharide containing arabinose containing galactose as a main constituent.

  As a tree species applicable to the raw material of the cosmetic of the present invention, any tree can be applied regardless of whether it is a broad-leaved tree or a conifer as long as the object of the present invention is not impaired. Preferably, larch containing a large amount of the above-mentioned active ingredients and rich in resources is selected.

During extraction process can be used Larch wood (core) part component of the pulverized material. You may use the mixture of the ground material of a woody part or a bark part. In addition, sawdust and the like generated by wood processing such as lumber can be used as a raw material.

  The size of the pulverized raw material, that is, the pulverized product, is preferably 1 cmφ (particle diameter) or less in consideration of extraction efficiency and ease of handling. Subsequently, the pulverized material is put in a container. As will be described later, the basic aqueous solution used for extraction has a relatively low concentration. Therefore, the material of the container is not particularly limited. What is necessary is just to select suitably the capacity | capacitance of the container according to the desired implementation scale suitably.

The pulverized product is immersed in an aqueous atmosphere of normal temperature (0 ° C. to 50 ° C.), preferably 10 ° C. to 30 ° C., with ammonia water or an aqueous sodium hydroxide solution. At this time, as an aqueous solution of the basic substance, an aqueous solution of potassium hydroxide (KOH), sodium carbonate (Na ₂ CO ₃ ), sodium hydrogen carbonate (NaHCO ₃ ) or the like may be applied.

  In view of cost, handling, etc. considering the extraction efficiency and the amount of the basic aqueous solution, in the extraction step in the cosmetic production method of the present invention, 0.025 to 0.25 mol / l, preferably It is suitable to use an aqueous solution of a basic substance at a concentration of 0.05 to 0.2 mol / l, particularly preferably an aqueous sodium hydroxide solution or an aqueous potassium hydroxide solution as an aqueous solution of the basic substance for extraction.

  The amount of the aqueous solution of the basic substance necessary for the immersion in the extraction step may be an appropriate amount between 100 and 1500% by weight with respect to the weight of the pulverized product. At this time, all of the pulverized material may be immersed in the basic solution.

  This immersion, that is, the extraction step, is preferably performed at the above-described temperature in an air atmosphere. The immersion time is preferably in the range of 30 minutes to 24 hours. The immersion time is preferably 1 hour in consideration of extraction efficiency.

  In this extraction step, for example, the volume of the pulverized product may be compressed using an apparatus such as a screw press. If it does in this way, the quantity of the aqueous solution of a basic substance required for extraction can be reduced as much as possible. That is, the usage amount of the aqueous solution of the basic substance can be reduced. If it does in this way, the cost of the drying process in a later process can be reduced.

  After the extraction step, the extract is preferably filtered off using, for example, filter paper (5C) or hollow core membrane (pore diameter 0.45 μm).

  The obtained extract is preferably left in a liquid state without drying immediately after extraction for the purpose of improving moisture retention and color tone. The standing time depends on the temperature at which it is allowed to stand, but is preferably 1 day to several days in an environment of room temperature (0 ° C. to 50 ° C.), preferably 1 to 7 days (24 hours to 168 hours). is there. The “environment” here refers to an external environment surrounding the extract, such as an air atmosphere or a thermostatic chamber.

  Also, the higher the temperature, the shorter the time for standing. For example, sufficient antibacterial activity, moisture retention, and improvement in color tone are expected by leaving it to stand for several hours under a temperature environment of about 50 ° C. Moreover, when it leaves still in the temperature environment of about 85 degreeC, about 1 hour may be sufficient. Even under such conditions, sufficient antibacterial activity, moisture retention, and color tone are expected to be improved.

  Specifically, the active component of the extract may be concentrated by standing for a predetermined time while performing a heating process of about 45 ° C. to 85 ° C., for example.

  The standing time of the extraction solution in the case of heating treatment may be a time that can improve the antibacterial activity, moisture retention, and color tone to a desired level. As a standard of the standing time accompanied by the heating treatment, for example, the active ingredient of the extraction solution may be concentrated to a desired concentration.

  Specifically, the time until the concentration of the active ingredient in the extraction solution is preferably concentrated at least 5 times, that is, 5 times or more, for example, may be used as a guide.

  In this way, if the standing time is set to a time at which the concentration of the active ingredient in the extraction solution is concentrated to 5 times or more, self-polymerization of the active ingredient taxifolin can be further promoted. Therefore, the moisture retention of the obtained cosmetic can be further improved. Moreover, if it does in this way, time required for a stationary time and the drying process mentioned later can be shortened more. Therefore, the manufacturing efficiency of cosmetics can be improved, and as a result, the manufacturing cost can be further reduced.

  Specifically, the standing step accompanied by the heating treatment can be performed in a state where the environment is kept at a predetermined temperature by using a heating means such as a thermostatic bath or a thermostatic chamber, for example.

  This standing step is a step in which the extraction solution is preferably left in an environment of 55 ° C. to 70 ° C. for a period of time until the concentration of the active ingredient in the extraction solution is concentrated at least 5 times. It is good.

  Further, the step of standing with heating treatment is more preferably a step of standing for 5 hours in a reduced pressure environment at 55 ° C. or 3 hours in a reduced pressure environment at 70 ° C.

  The term “under reduced pressure environment” as used herein refers to, for example, an environment in which the pressure is reduced to such an extent that the extraction solution does not bump using a rotary evaporator. The degree of this reduced pressure is preferably about 100 mmHg (13330 Pa), for example.

  By performing the standing step with heat treatment under such a reduced pressure environment, the standing time and the drying time of the drying step described later can be further shortened. Therefore, the production efficiency of the cosmetic of the present invention can be further improved, and the production cost can be further reduced.

  In addition, in this standing step, the standing step described above is shortened or replaced by performing a stirring step with supply of gaseous oxygen and an ultraviolet irradiation step on the extraction solution. be able to.

  The obtained extract may be sterilized before or after the standing step, if desired. As a specific sterilization method, a general method may be applied, for example, filtration with a filter having a pore size of 0.45 μm or less or ultrafiltration with a hollow membrane having a pore size of 0.45 μm or less before the standing step. Methods such as filtration can be used.

  When the sterilization treatment is performed after the standing step, the heat sterilization may be performed at 85 ° C. for 30 minutes, for example.

  Next, the obtained extract is dried using a method such as freeze drying or spray drying. In this drying step, when spray drying is performed, the extract is exposed to a temperature range of about 150 ° C., and thus the above-described sterilization treatment is not necessary. By this drying step, a powdery cosmetic can be obtained.

The cosmetic of the present invention is in the form of a powder having a color tone from brown to reddish purple. Since powdery cosmetics are extremely readily soluble in water (H ₂ O), they can be applied to various cosmetics in various modes. For example, the powdery cosmetic is mixed with other ingredients constituting the cosmetic having the desired properties while being in powder form, or preferably dissolved in water, a water-organic solvent mixed solution, an organic solvent, or the like. The dissolved solution is used by mixing with the other ingredients of the cosmetic product.

  Specifically, the powdery cosmetic or powdered cosmetic solution of the present invention is applied to cosmetics such as lotions, emulsions, creams, packs, powders, sprays, ointments, dispersions, and facial cleansers. It is preferable.

  The cosmetic of the present invention is characterized in that it has red and orange colors suitable for various cosmetics, as will be described in detail later. For example, when the cosmetic of the present invention is applied to a foundation, in addition to the above-described moisturizing property, antibacterial property and antioxidant property, the skin color is corrected by red to orange reflected interference light. be able to. That is, when the cosmetic of the present invention is contained in a cosmetic, the skin color can be corrected to a bright and transparent color tone and the function of making it appear healthier can be imparted to the cosmetic.

  Specific examples and comparative experimental examples according to the cosmetic of the present invention will be described below.

Example 1
Example 1-1
100 g of larch (Larix leprolepis Gordon) xylem (sawdust) (particle size of 1 cm or less) was treated with 900 ml of pure water at room temperature for 1 hour. The treated pulverized product was filtered using 5C filter paper, and the resulting extract was freeze-dried to obtain 4.2 g of a light brown powder.

  As a result of analysis by HPLC (high performance liquid chromatography), 95% by weight or more of the powder was arabinogalactan. This powder is hereinafter referred to as crude arabinogalactan.

Example 1-2
100 g of larch crushed material was treated with an aqueous NaOH solution having a concentration of 0.1 mol / l (liter) at room temperature for 1 hour. The treated pulverized product was filtered using 5C filter paper, and the resulting extract was freeze-dried to obtain 7.3 g of a light brown powder. As a result of analysis by HPLC, this powder contains approximately 30% to 60% by weight of water-soluble lignin, 30% to 60% by weight of arabinogalactan, and 10% to 20% by weight of polymerized taxifolin. It was. This powder is hereinafter referred to as larch base extract.

  Thus, the cosmetic of this invention contains a large amount of active ingredients. Therefore, according to the cosmetic production method of the present invention, a desired plurality of active ingredients can be extracted simultaneously and in a large amount by a simple process. Therefore, the cosmetic can be efficiently manufactured, and the manufacturing cost can be significantly reduced.

(Example 2)
A 0.1 wt% aqueous solution was prepared using the larch base extract obtained in Example 1. This aqueous solution was treated at room temperature for 0 hours (not allowed to stand), 5 hours, 1 day (24 hours), 2 days (48 hours), 5 days (120 hours), 6 days (144 hours), 7 It was allowed to stand for 14 days (336 hours) for 14 days (168 hours). Absorbance was measured using an absorptiometer at wavelengths of 600, 500 and 475 nm. The results are shown in Table 1. The wavelength of 500 nm corresponds to red, and the wavelength of 475 nm corresponds to orange. The right column shows the absorbance at a wavelength of 500 nm and a wavelength of 475 nm corrected by subtracting the absorbance at a wavelength of 600 nm corresponding to turbidity as a baseline correction.

  As is apparent from Table 1, the color tone of the larch base extract changes with time. Specifically, it changes from a yellowish reddish brown to a preferred reddish purple color. This preferable reddish purple color was found to have an absorbance at a wavelength of 500 nm of 0.500 or more (after correction) when defined by absorbance. Further, at this time, it was found that the absorbance at a wavelength of 475 nm was 0.500 or more (after correction).

  It can be seen that the absorbance at wavelengths of 500 nm and 475 nm increases markedly from 0 days of standing (not standing) to 1 day of standing (24 hours). That is, there is a marked improvement in color tone. There is almost no change in absorbance values up to 7 days (168 hours). That is, it can be said that a good color tone is maintained. However, on the 14th day of standing, it can be seen that the numerical value of absorbance decreases. That is, a slight deterioration of the color tone is observed on the 14th day of standing.

Example 3
Using the larch base extract obtained in Example 1, aqueous solutions each having a concentration of 1% by weight were prepared. While maintaining these aqueous solutions at 100 mmHg (13330 Pa) using a rotary evaporator in an environment of 55 ° C. or 70 ° C. using a thermostatic bath, the concentration of the larch base extract in the aqueous solution becomes 10% by weight, that is, the aqueous solution It was allowed to stand until the concentration of was concentrated 10 times.

  The time required for the concentration of each aqueous solution to be concentrated 10 times was about 5 hours in an environment at 55 ° C. and about 3 hours in an environment at 70 ° C. Hereinafter, the process of this example is referred to as a concentration process.

(Comparative Experimental Example 1: Comparison of moisture retention (1))
The moisturizing properties of the crude arabinogalactan obtained in Example 1-1 and the larch base extract obtained by standing for a predetermined time used in Example 2 were measured.

  0.25 g of crude arabinogalactan, standing time 0 hour (not standing), 1, 7, 14 days larch base extract was weighed and dissolved in 50 ml each of pure water. Accordingly, an aqueous solution having a concentration of 0.5% by weight was obtained. In order to correct the measurement error due to the position of the sample in the temperature-controlled room, crude arabinogalactan, 5 hours for each of the larch base extracts for 0 hours (not standing), 1, 7, 14 days A total of 28 samples including a sample and 3 pure water samples as controls were placed in a thermostatic chamber at 40 ° C., and the weight loss rate after 30 hours was measured.

  The results are shown in FIG. FIG. 1 is a graph showing the results of the moisture retention test. The results are the average of three pure water samples (graph A), crude arabinogalactan (graph B), standing time 0 hour (not standing) (graph C), and one day (graph). D), the larch base extract left standing for 7 days (graph E) and 14 days (graph F), and is shown by the average value of the results obtained from each 5 samples.

  As is clear from FIG. 1, it can be seen that the crude arabinogalactan exhibits a water evaporation suppression ability of about 7%, that is, moisture retention, compared to the evaporation rate of pure water (graph B). Similarly, the moisturizing property of the larch base extract (graph C) having a standing time of 0 hour (not standing) is less than 5%. That is, it is slightly inferior to the moisture retention of crude arabinogalactan.

  However, the larch base extract (graphs D to F) having a standing time of 1 day or longer was found to have significantly improved moisture retention. In particular, it was found that a larch base extract with a standing time of 7 days showed a moisture retention comparable to that of crude arabinogalactan. From this, it can be seen that the water evaporation suppression ability, that is, the moisture retention, is enhanced by the standing treatment.

  In addition, it was found that taxifolin, a polyphenol, self-polymerizes by standing treatment. This polymerized taxifolin contributes to further improvement of moisture retention.

(Comparative Experimental Example 2: Comparison of antioxidant activity (1))
Antioxidant activity of the larch base extract obtained in Example 1-2, the water-soluble lignin extracted from larch (larch extract), and the base extract of Ezo pine todomatsu mixed pulverized product (Ezo pine todomatsu base extract) Was measured respectively.

  First, sample preparation will be described. The spruce todomatsu base extract was prepared under the same conditions as the extraction method of the larch base extract in Example 1-2.

  The larch extract was prepared under the same conditions as the extraction method of the larch base extract in Example 1-2 after removing the water-soluble substance and the fat-soluble substance from the larch ground material in advance.

  The antioxidant activity test method will be described. First, in a test tube, 300 μl (microliter) of a DPPH (1,1-diphenyl-2-picrylhydrazyl) ethanol solution having a concentration of 400 μmol / l and a 0.2 M sodium acetate / acetate buffer (pH 6) is added. 0.0) 300 μl, 20% ethanol / water 300 μl was added and mixed. Catechin 1 μg, larch base extract (aqueous solution 50 μg, Ezo Todomatsu base extract (main component is lignin)) and larch extract (main component is water-soluble lignin) are added to this mixture. Sample solutions dissolved in 80 μl ethanol / water 300 μl were individually added and mixed, and the resulting sample mixed solutions were allowed to stand at room temperature for 20 minutes. As a sample, (+)-catechin (sigma) was used as a control substance, and a calibration curve was prepared in advance from the relationship between the amount of catechin added and the absorbance after the reaction.

  DPPH radical scavenging activity was evaluated as an antioxidant activity by the test method described above. The results are shown in FIG. FIG. 2 is a graph showing the measurement results of antioxidant activity. Graph A shows the antioxidant activity of catechin. Graph B shows the antioxidant activity of the larch base extract (standing time 0 hour). Graph C shows the antioxidant activity of the larch base extract (7 days standing). Graph D shows the antioxidant activity of the spruce Todomatsu base extract. Graph E shows the antioxidant activity of the larch extract.

  As shown in FIG. 2, it was found that the antioxidant activity of the larch base extract greatly exceeded the antioxidant activity of the spruce todomatsu base extract and the larch extract.

  Further, regarding the larch base extract, the antioxidant activity of 50 μg of the larch base extract that was not subjected to the static treatment was about 1.7 times the antioxidant activity of 1 μg of (+)-catechin. It was found to show activity. Furthermore, it was found that the antioxidant activity of 50 μg of larch base extract with a standing time of 7 days showed an antioxidant activity about 2.5 times that of 1 μg of (+)-catechin. That is, it was found that the antioxidant activity of 1 mg of larch base extract with a standing time of 7 days was comparable to the antioxidant activity of 48.5 μg of (+)-catechin.

  Thus, it was found that the cosmetic of the present invention has excellent antioxidant activity particularly when the raw material is derived from larch. Further, it was found that the antioxidant activity is remarkably enhanced by the standing treatment.

(Comparative Experimental Example 3: Comparison of moisture retention (2))
The moisturizing properties of the crude arabinogalactan and the larch base extract obtained by the concentration treatment of Example 3 were measured.

  A sample obtained by treating the concentrated crude arabinogalactan and larch base extract under the same conditions and steps as in Comparative Experiment 1 described above was placed in a constant temperature room at 40 ° C., and the weight loss rate after 30 hours was measured. did.

  The results are shown in FIG. FIG. 3 is a graph showing the results of the moisture retention test. The results were obtained from 5 samples each for an average of 3 pure water samples (graph A), 55 ° C. concentration treatment (graph B), and 70 ° C. concentration treatment (graph C) of larch base extract. The average value of the results is shown. Graph D is the result of the moisture retention test of crude arabinogalactan.

  As is clear from FIG. 3, it can be seen that the crude arabinogalactan exhibits a water evaporation suppression ability of about 8.9%, that is, moisture retention, compared to the evaporation rate of pure water (graph D). Similarly, the moisturizing property of the larch base extract (Graph B) concentrated in a 55 ° C. environment is improved by about 12% compared to the evaporation rate of pure water, and is concentrated in a 70 ° C. environment. It can be seen that the moisture retention of the larch base extract (graph C) is improved by about 13.3% compared to the evaporation rate of pure water.

  From the above, it can be seen that the self-polymerization of taxifolin is also promoted by the concentration treatment described in Example 3, and the water evaporation suppression ability, that is, the moisture retention is enhanced. In addition, by performing this concentration treatment, the standing time can be significantly shortened.

(Comparative Experimental Example 4: Comparison of antioxidant activity (2))
The antioxidant activity of the larch base extract obtained by the concentration treatment of Example 3 (the larch base extract obtained by the 55 ° C. concentration treatment and the 70 ° C. concentration treatment) was measured.

  This antioxidant activity test was performed under the same conditions and steps as in Comparative Experimental Example 2. Specifically, in a test tube, DPPH (1,1-diphenyl-2-picrylhydrazyl) ethanol solution having a concentration of 400 μmol / l, 300 μl (microliter) ethanol solution, 0.2 M sodium acetate / acetate buffer solution. (PH 6.0) 300 μl, 20% ethanol / water 300 μl were added and mixed. To this mixture, larch base extract (standing time 0 hour), larch base extract (standing time 7 days), 55 ° C. concentration treatment and 70 ° C. concentration treatment were obtained. Sample solutions dissolved in 300 μl of 80% ethanol / water were added separately and mixed. The obtained sample mixed solutions were each allowed to stand at room temperature for 20 minutes. Next, the absorbance at a wavelength of 520 nm was measured using the sample mixed solution after the stationary treatment as a sample. In advance, (+)-catechin manufactured by sigma was used as a control substance, and a calibration curve was prepared from the relationship between the amount of catechin added and the absorbance after the reaction.

  DPPH radical scavenging activity was evaluated as an antioxidant activity by the test method described above. The results are shown in FIG. FIG. 4 is a graph showing the measurement results of antioxidant activity. Graph A shows the antioxidant activity of the larch base extract (standing time 0 hour). Graph B shows the antioxidant activity of the larch base extract (7 days standing). Graph C shows a larch base extract obtained by concentration at 55 ° C. Graph D shows the antioxidant activity of the larch base extract obtained by concentration at 70 ° C.

  As shown in FIG. 4, the antioxidant activity of the larch base extract obtained by concentration treatment at 55 ° C. is significantly enhanced compared to the antioxidant activity of the larch base extract that was not subjected to the stationary treatment. It was seen. That is, it was found that the antioxidant activity was improved by about 13%. Moreover, it was found that the anti-oxidation activity was improved by about 8% for the larch base extract obtained by concentration treatment at 70 ° C.

  As described above, the cosmetic of the present invention suitable for application to various cosmetics has excellent moisture retention and antioxidant properties. Moreover, the cosmetic of this invention is excellent also in color tone.

It is a graph (1) which shows a moisture retention performance test result. It is a graph (1) which shows an antioxidant activity measurement result. It is a graph (2) which shows a moisture retention performance test result. It is a graph (2) which shows an antioxidant activity measurement result.

Claims (16)

A process of treating pulverized larch with a basic aqueous solution having a concentration of an aqueous solution of sodium hydroxide or potassium hydroxide of 0.025 mol / l or more and 0.25 mol / l or less, and filtering the pulverized product to obtain an extraction solution. When,
The extraction solution, in an environment of 50 ° C. from 0 ° C., the step of promoting the self-polymerization of taxifolin extracted with HazamaShizu location at 24-168,
A step of obtaining a solid cosmetic containing water-soluble lignin, arabinogalactan, and polymerized taxifolin by drying the extracted solution that has been allowed to stand. Production method. A process of treating pulverized larch with a basic aqueous solution having a concentration of an aqueous solution of sodium hydroxide or potassium hydroxide of 0.025 mol / l or more and 0.25 mol / l or less, and filtering the pulverized product to obtain an extraction solution. When,
The extraction solution is allowed to stand in an environment of 45 ° C. to 85 ° C. for a period of time until the concentration of the active ingredient in the extraction solution is at least 5 times concentrated, thereby promoting self-polymerization of taxifolin extracted. Process,
A step of obtaining a solid cosmetic containing water-soluble lignin, arabinogalactan, and polymerized taxifolin by drying the extracted solution that has been allowed to stand. Production method. In the step of promoting the self-polymerization of taxifolin, the extraction solution is allowed to stand in an environment at 55 ° C. to 70 ° C. for a time until the concentration of the active ingredient in the extraction solution is concentrated at least 5 times. It is a process, The manufacturing method of the cosmetics of Claim 2 characterized by the above-mentioned. The method for producing a cosmetic according to claim 3 , wherein the step of promoting self-polymerization of taxifolin is a step performed under a reduced pressure environment. 5. The method for producing a cosmetic according to claim 4 , wherein the step of promoting self-polymerization of taxifolin is a step of standing for 5 hours in a reduced pressure environment at 55 ° C. 5. The method for producing a cosmetic according to claim 4 , wherein the step of promoting self-polymerization of taxifolin is a step of standing for 3 hours in a reduced pressure environment at 70 ° C. The Larch grind, the manufacture of cosmetic according to any one of claims 1 to 6, characterized in that a mixture of pulverized xylem, or pulverized xylem and pulverized bark Method. The larch ground product, the concentration of the aqueous solution of sodium hydroxide or potassium hydroxide is treated with a basic aqueous solution is less than 0.025 mol / l or higher 0.25 mol / l, filtered and the solution extracted the pulverized 0 ° C. under 50 ° C. of environment from, to promote self-polymerization of taxifolin extracted to stand 24-168 hours, can give Rukoto Ri by the drying the extracted solution which had been allowed to stand, A solid cosmetic comprising water-soluble lignin, arabinogalactan, and polymerized taxifolin . An extract solution obtained by treating a pulverized larch with a basic aqueous solution having a concentration of an aqueous solution of sodium hydroxide or potassium hydroxide of 0.025 mol / l or more and 0.25 mol / l or less, and separating the pulverized product by filtration , In an environment of 45 ° C. to 85 ° C., it promotes the self-polymerization of taxifolin extracted by standing for a period of time until the concentration of the active ingredient in the extraction solution is concentrated at least 5 times. the extraction solution can give Rukoto Ri by the drying the Oita, water-soluble lignin, arabinogalactan, and polymerized solid cosmetics containing taxifolin. An extract solution obtained by treating a pulverized larch with a basic aqueous solution having a concentration of an aqueous solution of sodium hydroxide or potassium hydroxide of 0.025 mol / l or more and 0.25 mol / l or less, and separating the pulverized product by filtration , To promote self-polymerization of taxifolin extracted by standing for a period of time until the concentration of the active ingredient in the extraction solution is concentrated at least 5 times in an environment of 55 ° C to 70 ° C and drying. it is obtained Rukoto Ri good, water-soluble lignin, arabinogalactan, and polymerized solid cosmetics containing taxifolin. An extract solution obtained by treating a pulverized larch with a basic aqueous solution having a concentration of an aqueous solution of sodium hydroxide or potassium hydroxide of 0.025 mol / l or more and 0.25 mol / l or less, and separating the pulverized product by filtration , under a reduced pressure environment of 55 ° C., 5 hours, taxifolin to promote standing self-polymerization of taxifolin extracted, it is obtained Rukoto Ri by the drying, water-soluble lignin, arabinogalactan, and polymerized A solid cosmetic containing An extract solution obtained by treating a pulverized larch with a basic aqueous solution having a concentration of an aqueous solution of sodium hydroxide or potassium hydroxide of 0.025 mol / l or more and 0.25 mol / l or less, and separating the pulverized product by filtration , under a reduced pressure environment of 70 ° C., 3 hours, allowed to stand and to promote the self-polymerization of taxifolin extracted, the dried water-soluble lignin can by Ri obtained Rukoto to, arabinogalactan, and polymerized the taxifolin Contains solid cosmetics. The cosmetic material according to any one of claims 8 to 12, wherein the pulverized product of larch is a pulverized product of a xylem, or a mixture of a pulverized product of a xylem and a crushed product of bark. The water-soluble lignin 30 wt% to 60 wt%, arabinogalactan 30 wt% to 60 wt%, and claim 8 which polymerized the taxifolin, characterized in that it contains in the range of 10% to 20% 14. Cosmetics as described in any one of 13 . The cosmetic according to any one of claims 8 to 14 , wherein the absorbance at a wavelength of 500 nm is 0.500 or more in a 0.1 wt% aqueous solution. A cosmetic comprising 0.01% to 1.0% by weight of the cosmetic according to any one of claims 8 to 15 .

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