JP3679219B2

JP3679219B2 - Multi-chamber container

Info

Publication number: JP3679219B2
Application number: JP05989497A
Authority: JP
Inventors: 冨士夫井上; 雅満泉
Original assignee: Otsuka Pharmaceutical Co Ltd
Current assignee: Otsuka Pharmaceutical Co Ltd
Priority date: 1997-02-26
Filing date: 1997-02-26
Publication date: 2005-08-03
Anticipated expiration: 2017-02-26
Also published as: JPH10236540A

Description

【０００１】
【発明の属する技術分野】
本発明は粉末剤、液剤、固形剤等を封入する可撓性複室容器の改良に関するものである。本発明の複室容器は、例えば吸湿性や易酸化性を有する薬剤等を収容するのに使用すれば、特に有効である。
【０００２】
【従来の技術】
従来より吸湿性や易酸化性を有する薬剤等と、溶解液や希釈液等とを隣合う別の室に分離して収容し、使用時にシール部を連通させて混合するようにした複室容器が用いられているが、複室容器には吸湿性や易酸化性を有する薬剤等を収容した室を水分非透過性および／またはガス非透過性のフィルムで覆って密封し、内側の空間部に脱酸素剤や乾燥剤等を封入したり、あるいはこのような薬剤等を収容する室自体を水分吸収性や酸素非透過性の層を有するフィルムで形成したりすることが行われている。例えば、前者としては特開平４ー３６４８５１号の複室容器、後者としては特開平８ー２８０７７５号の可撓性複室容器等が該当する。
【０００３】
【発明が解決しようとする課題】
ところが、前者の複室容器では、吸湿性や易酸化性を有する薬剤等を収容した室と、これを覆う水分非透過性および／またはガス非透過性のフィルムとの間の空間部に脱酸素剤や乾燥剤等を単に入れるだけであるので、脱酸素剤、乾燥剤等は空間部内を自由に移動し、前記室内の薬剤等と重なった場合には、複室容器自体がかさばるという問題点があり、後者の可撓性複室容器では、室を形成するリアーシートとフロントシートのうちの一方のシートにのみ吸水層（水分吸収性を有する層）が存在するのみで、かつ吸水層の片側の面が直接もしくは水分透過性の層を介して室内に接するだけであるから、水分吸収面積が自ずから制約され、室内湿気の吸収量を充分に確保し難いという問題点があり、また、酸素非透過性フィルムで外部と遮断するだけであるから、室内に存在する酸素の影響を避けることができないという問題点があった。
本発明はこのような事情を背景としてなされたものであり、本発明の目的は
脱酸素剤や乾燥剤等の封入個所内での移動を制限し、かつ室内の水分や酸素の影響を少なくなし得る複室容器を提供しようとするものである。
【０００４】
【課題を解決するための手段】
本発明はこのような目的を達成するためになされたものであり、本発明は下記の通り構成されている。
Ａ可撓性フィルムで粉末剤、液剤、固形剤を収容するための複数の室が形成され、かつ隣合う室を密封状態に仕切る手段として剥離可能なシール部を含むようにし、さらに該複数の室の内の１または２以上の室を水分非透過性および／またはガス非透過性のフィルムで覆い密封された空間部を生ずるようにした複室容器において、前記空間部を溶着部と非溶着部が交互に連なって配置されるようにした単数もしくは複数の非密封性仕切部により横切るように区分して、単数の非密封性仕切部を設けたときにあっては一方の区分を粉末剤、液剤、固形剤を収容する室を被覆する対象物収容室被覆区とし、他方の区分を脱酸素剤、乾燥剤、酸素吸収性シート、水分吸収性シートを収容する補助剤収容区とし、複数の非密封性仕切部を設けたときにあっては前記補助剤収容区は複数に区分されて脱酸素剤、乾燥剤、酸素吸収性シート、水分吸収性シートを収容可能とし、かつ各区分は前記非溶着部の隙間を通じて互いに連通可能としたことを特徴とする複室容器。
Ｂ前記Ａ項記載の複室容器において、複室容器自体を吊下げるための吊下げ部を前記補助剤収容区に一体に形成した複室容器。
Ｃ可撓性フィルムで粉末剤、液剤、固形剤を収容するための複数の室が形成され、かつ隣合う室を密封状態に仕切る手段として剥離可能なシール部を含むようにし、さらに該複数の室の内の１または２以上の室を水分非透過性および／またはガス非透過性のフィルムで覆い密封するようにした複室容器において、前記水分非透過性および／またはガス非透過性のフィルムで覆われる室を１室のみとし、該室を溶着部と非溶着部が交互に連なって配置されるようにした単数もしくは複数の非密封性仕切部により横切るように区分して、単数の非密封性仕切部を設けたときにあっては一方の区分を粉末剤、液剤、固形剤を収容する対象物収容区とし、他方の区分を脱酸素剤、乾燥剤、酸素吸収性シート、水分吸収性シートを収容する補助剤収容区とし、複数の非密封性仕切部を設けたときにあっては前記補助剤収容区は複数に区分されて脱酸素剤、乾燥剤、酸素吸収性シート、水分吸収性シートを収容可能とし、かつ各区分は前記非溶着部の隙間を通じて互いに連通可能としたことを特徴とする複室容器。
Ｄ前記Ｃ項記載の複室容器において、前記補助剤収容区を構成する前後両面の可撓性フィルムを密着する程に接近させ、しかも両フィルム間に封入された脱酸素剤、乾燥剤、酸素吸収性シート、水分吸収性シートの周辺部は前記非密封性仕切部の隙間を通じて隣合う対象物収容区に連通可能とし、かつ補助剤収容区の一端部を直接前記室を覆う水分非透過性および／またはガス非透過性のフィルムに連結したことを特徴とする複室容器。
Ｅ前記Ａ項ないしＤ項のいずれか１項に記載の複室容器において、前記複数の室のうち水分非透過性および／またはガス非透過性のフィルムで覆われた室に、さらには非密封性仕切部により区分された室にあっては対象物収容区に吸湿性および／または易酸化性を有する粉末剤、液剤、固形剤を収容するようにした複室容器。
Ｆ前記Ａ項ないしＥ項のいずれか１項に記載の複室容器において、水分非透過性および／またはガス非透過性のフィルムで形成された内部空間に酸素吸収性シートおよび水分吸収性シートのいずれか一方もしくは両方を前記内部空間を形成する前記フィルムに連結した状態で封入するようにした複室容器。
Ｇ前記Ａ項ないしＦ項のいずれか１項に記載の複室容器において、前記水分非透過性および／またはガス非透過性のフィルムと該フィルムで覆われた室を構成するフィルムの全部もしくは一部を吸水層および／または酸素吸収層を有するフィルムとし、前記水分非透過性および／またはガス非透過性のフィルムで形成された内部空間および前記室内の水分および／または酸素を吸収するようにした複室容器。
ここに、「非密封性仕切部」とは溶着部が列状に配置された場合に限らず、ジグザグ状や散点状もしくは帯状等をなすように配置された場合も含むものであり、「粉末剤、液剤、固形剤を収容」とはこれらのいずれか１または２以上を収容することを意味し、「脱酸素剤、乾燥剤、酸素吸収性シート、水分吸収性シートを収容」とはこれらのいずれか１または２以上を収容することを意味する。
【０００５】
【発明の実施の形態】
以下本発明の実施例を記載した図面に基づいて、発明の実施の形態を詳細に説明する。
図１は本発明の実施例（請求項１記載の複室容器）を示す。図１において、２は液剤を収容するための室４を構成するフィルム、６は粉末剤等を収容するための室８を構成するフィルム、１０は室８を覆う被覆区１１と乾燥剤１６、脱酸素剤１８を収容する補助剤収容区１２とからなる室１４を構成するフィルムである。すなわち、室１４は溶着部１９と非溶着部２０とが交互に配列された非密封性仕切部２１により２つに区分され、一方が補助剤収容区１２をなし、他方が被覆区１１をなしている。そして、両区１１、１２は図１（ホ）に示すように非溶着部２０の隙間Ｓを通じて互いに連通可能とされている。なお、前記被覆区１１は粉末剤、液剤、固形剤等を収容するための収容室を被覆するいわゆる対象物収容室被覆区に相当し、前記補助剤収容区１２は脱酸素剤、乾燥剤、酸素吸収性シート、脱酸素剤等を収容する補助剤収容区に相当し、被覆区１１と補助剤収容区１２とからなる室１４は請求項１記載の空間部に相当する。
【０００６】
室４には液剤が封入されると共に口部２２が取り付けられ、室８には粉末剤が封入されている。室８は２枚重ね合わせたフィルム６の周縁を溶着して形成される。すなわち、フィルム６は図１（ハ）に示すようにポリエチレン（以下ＰＥと略記する）からなる外層２６とＰＥとポリプロピレン（以下ＰＰと略記する）との混合樹脂からなる内層２８との多層フィルムであり、２枚の多層フィルムが周縁で溶着されて室８が形成される。
【０００７】
一方室４は、多層フィルムである前記フィルム６が下方に伸び、溶着されて構成される。すなわち、前記多層フィルムを２枚重ね合わせ、その周縁部を溶着すると共に、その中間部において横方向に、周縁部より強度が小さくなる状態に溶着し、仕切り手段としての弱シール部３０を形成し、これを境にして室８、室４が形成される。
【０００８】
被覆区１１と補助剤収容区１２とからなる室１４は、２枚重ね合わせたフィルム１０の周縁を溶着すると共に、中間部で横方向の非密封性仕切部２１により２つに区分されて形成される。すなわち、フィルム１０は図１（ニ）に示すように、内層３４がＰＥで、外層３６が水分非透過性、ガス非透過性のバリアーフィルムからなる多層フィルムであり、バリアーフィルムとして例えばポリエチレンテレフタレート（以下ＰＥＴと略記する）とポリ塩化ビニリデンとＰＥの３重層または、ＰＥＴとポリビニルアルコールのシリカ蒸着フィルムとＰＥとの３重層が使用されている。そして、室８を覆って上方に余りある状態に２枚の上記多層フィルムが配置され、その左右周縁および上部周縁がそれぞれ互いに溶着され、下部周縁は図１（ヘ）に示すように弱シール部３０上に重ね合わせて溶着され、さらにその中間部では図１（イ）に示すように、横方向に溶着部１９と非溶着部２０が交互に配置されるようにした非密封性仕切部２１が設けられ、これを境にして被覆区１１と補助剤収容区１２が形成される。被覆区１１と補助剤収容区１２は、外気とは完全に遮断されているが、非密封性仕切部２１の非溶着部を通じて互いに連通可能とされている。３２は複室容器上端部に形成された吊下げ用孔である。
【０００９】
なお、非溶着部２０の隙間は補助剤収容区１２内に封入する乾燥剤や脱酸素剤等の補助剤（酸素吸収性シート、水分吸収性シート等を含む）が隣りの被覆区１１に移動できない程度の大きさに決定される。上記多層フィルムを溶着する際、補助剤収容区１２内に乾燥剤１６と脱酸素剤１８が封入される。乾燥剤としては、例えばシリカゲル、ゼオライト、シリカゲル成形物、脱酸素剤一体物等が使用されている。また、脱酸素剤としても、市販のもの、例えば三菱瓦斯化学社製「エージレス（登録商標）」や、アモルファス銅を用いた脱酸素剤等が使用できる。
【００１０】
補助剤収容区１２内の乾燥剤１６と脱酸素剤１８に代えて、図１（ト）に示すように水分吸収性シート３８や酸素吸収性シート４０を配置してもよい。配置の方法としては、同図に示すように各シート３８、４０をフィルム１０に溶着や接着等して固定する他、単に補助剤収容区１２内に封入する等してもよい。また、補助剤収容区１２内に図１（チ）に示すように細切りした水分吸収性シート４２、酸素吸収性シート４４を充填してもよい。シート４２、４４の総表面積を広くなし得る利点がある。さらに、フィルム１０自体を水分吸収性シートや酸素吸収性シートとすることも可能である。なお、例えば、水分吸収性シートの水分吸収層を構成するものとしては、佐々木化学薬品株式会社製ドライキープ（登録商標）等が、酸素吸収性シートの酸素吸収層を構成するものとしては、東洋製罐株式会社製オキシガード（０ＸＹＧＵＡＲＤ）（登録商標）等が好適に使用できる。
【００１１】
なお、各部の溶着に当たって溶着温度は、室８、室４の周縁部および室１４の周縁部が最も高く、約１７０〜２００℃であり、弱シール部３０はこれより低く、約１１０〜１３０℃であり、さらに、フィルム６とフィルム１０との溶着部および非密封性仕切部２１の溶着部は、室８、室４の周縁部および室１４の周縁部とほぼ同じ１６５〜２１５℃で溶着される。
【００１２】
以上のように構成された実施例においては、乾燥剤と脱酸素剤を封入した補助剤収容区１２と被覆区１１を構成するフィルム１０は、水分非透過性、ガス非透過性のバリアーフィルムが使用されると共に、室８を構成するフィルム６は外層がＰＥ、内層がＰＥとＰＰとの混合樹脂からなる水分透過性、ガス透過性の多層フィルムから構成されているので乾燥剤、脱酸素剤はそれぞれ粉末剤の乾燥や易酸化性を有する薬剤の酸化防止を効率よく行なうことができる。また、室８を直接覆う被覆区１１とは、別に乾燥剤や脱酸素剤を収容する補助剤収容区１２を設けているので、従来の１つの空間部に乾燥剤等を収容していた場合に比し、乾燥剤等収容時のまとまりがよく、また、乾燥剤等が大きく移動しないので、乾燥剤等が、粉末剤を収容した室８に重なり合ってかさ張ることがなく好都合である。なお、補助剤収容区１２と被覆区１１の両方に乾燥剤や脱酸素剤または水分吸収性シート、酸素吸収性シート、あるいはこれらを一緒に収容することも可能である。さらに、フィルム６、１０として透明フィルムを使用すれば、内部の状態を目視できる。そして、室４に指等で一定の圧力を加えることにより弱シール部３０が剥離し、室４と室８が連通され、液剤と粉末剤が無菌状態で混合されて溶解する。
【００１３】
なお、上記実施例の粉末剤として例えば、抗生剤、抗癌剤、ステロイド剤、血栓溶解剤またはビタミン剤等の吸湿性、易酸化性および易熱変性の物質が挙げられ、液剤としてこれらの溶解液または希釈液、例えば生理食塩液や、ブドウ糖液および注射用蒸留水などが挙げられる。粉末剤の抗生剤等の中には、下部の液剤で溶解する前に、炭酸ナトリウム等のアルカリ溶剤や他の溶解補助剤で溶解しなければならないものがあるが、このような場合には、この粉末剤を収容した室に溶剤等を混注するための注入口（図示省略）を設ける。
【００１４】
フィルム６としては、上記実施例に記載された多層フィルム以外にも、ＰＥ、ＰＰおよびこれらの混合樹脂から選ばれる一種以上の組合せによる単層もしくは多層フィルムを使用することも可能であり、好ましくは、フィルム６の内層を直鎖状低密度ポリエチレン（以下ＬＬＤＰＥと略記する）とＰＰとの混合樹脂とし、外層をＬＬＤＰＥとした２層フィルムを用いることができる。フィルム１０にはポリ塩化ビニリデン、ＰＥＴ、アルミ加工フィルム、エチレンビニルアルコール共重合体（ＥＶＯＨ）、シリカ蒸着フィルムの単層もしくは多層のシートを使用することも可能である。なお、フィルム６とフィルム１０を直接溶着する場合、溶着を良好にするために少なくともフィルム１０を多層フィルムとし、フィルム１０の最内層の材質とフィルム６もしくはフィルム６の最外層の材質とを同一にすることが望ましい。例えば、フィルム６の最外層がＬＬＤＰＥの場合、フィルム１０の最内層にはＬＬＤＰＥを用いることが望ましい。
【００１５】
前記実施例ではフィルム１０で覆われた室８内に粉末剤を封入し、フィルム１０で覆われない室４内に液体を封入したが、目的に応じて粉末剤を液剤に、液剤を粉末剤に変えて封入することも可能である。
フィルム１０で覆われた室内に液剤を封入し、他の室内に粉末剤を封入する例として、例えば液剤としてシステインまたはトリプトファンをそれぞれ添加したアミノ酸製剤等の易酸化性の物質が挙げられ、粉末剤として糖もしくは電解質、またはこれらの混合物等が挙げられる。この場合補助剤収容区１２には脱酸素剤のみを封入する。フィルム１０で覆われた室８内に液剤を封入し、他の室内に他の液剤を封入する例としては、例えば前者の液剤としてシステインまたはトリプトファンをそれぞれ添加したアミノ酸製剤あるいはビタミン剤の易酸化性の物質が挙げられ、後者の液剤としては糖・電解質液が挙げられる。
【００１６】
また他の例としては、前者の液剤として脂肪乳剤等の易酸化性の物質が、後者の液剤としては糖・電解質液等が挙げられる。
さらに、いずれか一方の室内に固形剤を、他の室内に液剤を封入することも可能である。さらにまた、上記粉末剤、液剤、固形剤の例として、経静脈または経腸（経管、経口）投与する他の種々の栄養剤や治療剤等が挙げられる。
また補助剤収容区１２に封入した乾燥剤と脱酸素剤は必要に応じていずれか一方のみ使用することも可能である。さらに、フィルム１０の一部または全部にアルミ加工フィルムを使用し、内部を遮光するようにしてもよい。なお、フィルム１０に使用されたアルミ加工フィルムは、使用時必要に応じその一部または全部が剥離可能であってもよい。
【００１７】
前記実施例は液剤と１種の粉末剤とを封入する２室容器の例であるが、２室以上でも適用可能である。例えば、フィルム１０で覆われた被覆区１１内に粉末剤、固形剤、液剤等を封入する室を複数個設けたり、フィルム１０で覆われない室を複数設けることも可能である。また、前記実施例は室１４を非密封性仕切部２１により上下に区分したが、上下方向の非密封性仕切部により室１４を左右に区分することも可能である。非密封性仕切部を複数設け室１４を２以上に区分することも可能である。
【００１８】
また、前記実施例では、弱シール部３０の形成は室８を構成する２枚のフィルム１０の内面同士を直接溶着する、いわゆる直接溶着方式で行なっているが、これに代えてこのシート間に多層インサートフィルムを挟んだ状態で溶着し、弱シール部を形成させる、いわゆる多層インサートフィルム挟持溶着方式で行なってもよい。図２は２層インサートフィルムを使用した例を示す。この場合４８は室８を構成するフィルムで単層フィルムまたは多層フィルムであり、５０はフィルム４８またはフィルム４８の最内層のシートに対して熱接着力の強いシート、５２は反対側のフィルム４８またはフィルム４８の最内層のシートに対して熱接着力の弱いシートであり、弱シール部５４が形成されている。
【００１９】
例えば、フィルム４８がＰＥまたはＰＰの単層フィルムである場合には、５０はこれと同じＰＥまたはＰＰのシートであり、５２はＰＥとＰＰとの混合樹脂である。この例ではフィルム４８を２枚重ね合せて周縁を溶着して袋状にしているが、これに代えてチューブ状のフィルムを使用し、中間部に孔をあけ、そこからシート５０、５２を挿入し、しかる後チューブ状フィルムの外側から押付けた状態で溶着し、弱シール部を形成させることも可能である。
【００２０】
図３は本発明の他の実施例（請求項２記載の複室容器）を示す。なお、前記実施例と変更を要しない部分については、同一番号を付して詳しい説明は省略する（以下同じ）。室４、８、被覆区１１、弱シール部３０および非密封性仕切部２１は、前記実施例と同様に構成されているが、補助剤収容区１２が同時に吊下げ部５６を兼ねている点で前記実施例と異なる。すなわち、吊下げ部５６は、２枚重ね合せたフィルム１０の左右および上部の周縁並びに中央部付近に設けられた吊下げ孔６０の周縁が溶着されると共に、下部は非密封性仕切部２１によって被覆区１１に隣合うようにされている。吊下げ部５６の内部空間は補助剤収容区１２をなし、前記周縁の溶着部によって外部と遮断されているが、非密封性仕切部２１の隙間を通じて被覆区１１と連通されている。吊下げ部５６は、被覆区１１を構成する前記多層のフィルム１０が上方に伸び、その周縁および吊下げ孔６０の周縁が溶着されて構成される。吊下げ部５６の内部空間である補助剤収容区１２には乾燥剤１６や脱酸素剤１８が封入されるが、これに代えて水分吸収性シートや酸素吸収性シートを封入したり、またこれらを一緒に封入してもよく、あるいは内部に吸水層や酸素吸収層を有するフィルムを使用して吊下げ部５６を構成することも可能である。本実施例によれば、吊下げ部のスペースが有効に活用できる利点がある。
【００２１】
図４は本発明のさらに他の実施例（請求項３記載の複室容器）を示す。フィルム２からなる室４に、弱シール部３０を介して対象物収容区６２と補助剤収容区６４とからなる室６６が隣接し、かつ室６６は、非密封性仕切部２１を介して前記２つの区６２、６４に区分され、両区は非密封性仕切部２１の隙間を通じて互いに連通可能とされたものである。補助剤収容区６４、対象物収容区６２は室４を構成する前後両側のフィルム２が上方に伸び、その左右および上部の周縁が溶着されると共に、中間部は非密封性仕切部２１により２分されて構成される。補助剤収容区６４、対象物収容区６２は、前記フィルム１０と同様な多層のフィルム６８に覆われ、空間部７０内に位置するようにされている。補助剤収容区６４内には、乾燥剤１６や脱酸素剤１８が封入されるが、これに代えて水分吸収性シートや酸素吸収性シートを封入したり、またこれらを一緒に封入してもよく、あるいは吸水層や酸素吸収層を有するフィルムを使用して、補助剤収容区６４を構成することも可能である。
【００２２】
図５は本発明の別の実施例（請求項４記載の複室容器）を示す。補助剤収容区６４を構成する前後のフィルム（室４を構成するフィルム２が上方に延びたもの）を互いに接近させて内部空間を偏平状にし、さらに、そのフィルムは上方に伸びて連結部７２をなし、その上端部がフィルム６８と一緒に溶着されたものである。補助剤収容区６４が偏平状である点と補助剤収容区６４を構成するフィルムの上端が、空間部７０を構成するフィルムに連結されている点を除けば図４に示す複室容器と同じである。
【００２３】
前記各実施例の水分非透過性、ガス非透過性のバリアーフィルムで覆われた空間部内に位置する室には、吸湿性や易酸化性の粉末剤、液剤、固形剤等が収容される。前記実施例では、補助剤収容区６４、対象物収容区６２は室４、８を構成するフィルムと連続したフィルムで構成されるが、別体のフィルムを接合して構成してもよい。また、室４と室８も同様である。
以上本発明のいくつかの実施例について説明したが、本発明はこのような実施例に何等限定されるものではなく、本発明の要旨を逸脱しない範囲において種々なる態様で実施し得ることはもちろんである。
【００２４】
【発明の効果】
本発明は上述の通り構成されているので、次に記載する効果を奏する。
請求項１〜請求項６記載の複室容器によれば、水分非透過性、ガス非透過性のバリアーフィルムで覆われた空間部内もしくは薬剤等を収容する室内を非密封性仕切部で区分した区画内に乾燥剤、脱酸素剤、水分吸収性シート、酸素吸収性シート等を封入するようにしたので、乾燥剤等は非密封性仕切部に阻まれ、隣り合う薬剤等を収容する区画内に移動できず、従って複室容器の包装がかさ張らないという利点がある。また、薬剤等を収容する室内に乾燥剤等を封入するので、前記バリアーフィルムで覆われた空間部内に乾燥剤等を封入していた従来例に比し、収容個所の制約が少なくなり、収容個所選択の自由度が大きくなるという利点がある。
請求項２記載の複室容器によれば、吊下げ部のスペースを有効に活用できる利点がある。
請求項３〜請求項５記載の複室容器によれば、薬剤等を収容する室内に乾燥剤等を直接封入するので、吸湿防止や酸化防止の効果が大きい。
請求項７記載の複室容器によれば、前記バリアーフィルムや前記室を構成するフィルムを水分吸収層や酸素吸収層を有するフィルムで構成するので、複室容器自体がコンパクトになるという利点がある。
【図面の簡単な説明】
【図１】（イ）〜（ヘ）は本発明の一実施例を示す正面図、縦断面図、Ａ部拡大断面図、Ｂ部拡大断面図、Ｃ部拡大断面図、Ｄ図拡大断面図、（ト）〜（チ）はそれぞれ同実施例の変形例を示す部分断面図である。
【図２】上記実施例の変形例を示す部分拡大断面図である。
【図３】（イ）〜（ハ）は本発明の他の実施例を示す正面図、Ｅ−Ｅ断面図、部分拡大断面図である。
【図４】（イ）、（ロ）は本発明のさらに他の実施例を示す正面図と縦断面図である。
【図５】（イ）〜（ハ）は本発明の別の実施例を示す正面図、縦断面図、部分拡大断面図である。
【符号の説明】
２フィルム
４室
６フィルム
８室
１０フィルム
１１被覆区（対象物収容室被覆区）
１２補助剤収容区
１４室
１６乾燥剤
１８脱酸素剤
１９溶着部
２０非溶着部室
２１非密封性仕切部
３０弱シール部
３８水分吸収性シート
４０酸素吸収性シート
５４弱シール部
５６吊下げ部
６２対象物収容区
６４補助剤収容区
６６室
６８フィルム
７０空間部[0001]
BACKGROUND OF THE INVENTION
The present invention relates to an improvement of a flexible multi-chamber container that encloses a powder agent, a liquid agent, a solid agent and the like. The multi-chamber container of the present invention is particularly effective when used for accommodating a drug having hygroscopicity or easily oxidization, for example.
[0002]
[Prior art]
A multi-chamber container that separates and stores a hygroscopic or easily oxidizable drug, etc., and a solution or diluent, etc., in a separate adjacent chamber, and communicates and mixes the seal portion during use. However, in a multi-chamber container, a chamber containing a hygroscopic or easily oxidizable drug is covered and sealed with a moisture-impermeable and / or gas-impermeable film, and the inner space is sealed. An oxygen scavenger, a desiccant, or the like is enclosed in the chamber, or a chamber itself containing such a drug is formed of a film having a moisture-absorbing or oxygen-impermeable layer. For example, the former is a multi-chamber container disclosed in Japanese Patent Laid-Open No. 4-364851, and the latter is a flexible multi-chamber container disclosed in Japanese Patent Laid-Open No. 8-280775.
[0003]
[Problems to be solved by the invention]
However, in the former multi-chamber container, oxygen is removed in the space between the chamber containing the hygroscopic or easily oxidizable drug and the moisture-impermeable and / or gas-impermeable film covering the chamber. Since the deoxidant, desiccant, etc. can move freely in the space and overlap with the chemicals in the room, the multi-chamber container itself is bulky. In the latter flexible multi-chamber container, there is only a water absorbing layer (layer having moisture absorption) on one of the rear sheet and the front sheet forming the chamber, and the water absorbing layer Since the surface on one side is only in contact with the room directly or through a moisture permeable layer, the moisture absorption area is naturally limited, and it is difficult to ensure sufficient absorption of room moisture. Non-permeable film blocks outside Since that is only, there is a problem that it is not possible to avoid the influence of oxygen present in the room.
The present invention has been made against the background of such circumstances, and the object of the present invention is to limit the movement of oxygen scavengers, desiccants and the like within the enclosure, and to reduce the influence of moisture and oxygen in the room. It is intended to provide a multi-chamber container to obtain.
[0004]
[Means for Solving the Problems]
The present invention has been made to achieve such an object, and the present invention is configured as follows.
A. A plurality of chambers for accommodating a powder agent, a liquid agent, and a solid agent are formed with a flexible film, and a peelable seal portion is included as a means for partitioning adjacent chambers in a sealed state. In a multi-chamber container in which one or two or more chambers in a chamber are covered with a moisture-impermeable and / or gas-impermeable film to form a sealed space, the space is not welded to the weld When one or more non -sealable partitioning parts are provided so as to be crossed by one or a plurality of non -sealable partitioning parts, the one part is a powder agent. The object storage chamber covering section that covers the chamber for storing the liquid agent and the solid agent, and the other section as the auxiliary agent storage section for storing the oxygen absorber, the desiccant, the oxygen absorbing sheet, and the moisture absorbing sheet, When multiple non-sealing partitions are provided In this case, the auxiliary agent storage section is divided into a plurality of sections so as to store oxygen absorbers, desiccants, oxygen-absorbing sheets, and moisture-absorbing sheets , and the sections can communicate with each other through the gap of the non-welded portion. A multi-chamber container characterized by that.
B In the multi-chamber container described in the item A, a multi-chamber container in which a hanging portion for suspending the multi-chamber container itself is integrally formed in the auxiliary agent storage area.
C a plurality of chambers for accommodating powder agent, liquid agent, and solid agent are formed in the flexible film, and a peelable seal portion is included as means for partitioning adjacent chambers in a sealed state, and the plurality of chambers are further included. In a multi-chamber container in which one or more of the chambers are covered and sealed with a moisture-impermeable and / or gas-impermeable film, the moisture-impermeable and / or gas-impermeable film the covered Ru chamber is only one room, with divided across a single or a plurality of non-occlusive partition portion which is adapted unwelded portion and the welding portion of the chamber is arranged continuous with the alternate, the singular When the non-sealing partition is provided, one section is set as an object storage section for storing a powder agent, a liquid agent, and a solid agent, and the other section is an oxygen scavenger, a desiccant, an oxygen absorbing sheet, Adjuvant storage area for storing moisture-absorbing sheets And when the plurality of non-sealing partitions are provided, the auxiliary agent containing section is divided into a plurality of parts and can contain an oxygen scavenger, a desiccant, an oxygen absorbent sheet, a moisture absorbent sheet , and A multi-chamber container characterized in that each section can communicate with each other through a gap in the non-welded portion.
D In the multi-chamber container described in the above section C, the oxygen absorber, the desiccant, and the oxygen which are brought into close contact with each other so that the flexible films on both the front and rear sides constituting the auxiliary agent storage area are in close contact with each other The peripheral portion of the absorbent sheet and the moisture absorbent sheet can communicate with the adjacent object storage area through the gap of the non-sealing partition part, and one end of the auxiliary agent storage area directly covers the chamber. And / or a multi-chamber container connected to a gas-impermeable film.
E The multi-chamber container according to any one of the items A to D, wherein the chamber covered with a moisture-impermeable and / or gas-impermeable film is further unsealed. A multi-chamber container in which a powder agent, a liquid agent, and a solid agent having hygroscopicity and / or oxidization property are accommodated in an object accommodation area in a room divided by a sex partition.
F In the multi-chamber container according to any one of Items A to E, an oxygen-absorbing sheet and a moisture-absorbing sheet are formed in an internal space formed of a moisture-impermeable and / or gas-impermeable film. A multi-chamber container in which either one or both are sealed in a state of being connected to the film forming the internal space.
G In the multi-chamber container described in any one of the items A to F, all or one of the films constituting the moisture-impermeable and / or gas-impermeable film and the chamber covered with the film. The portion is a film having a water absorbing layer and / or an oxygen absorbing layer, and absorbs moisture and / or oxygen in the interior space and the chamber formed by the moisture impermeable and / or gas impermeable film. Multi-chamber container.
Here, the `` non-sealing partition part '' includes not only the case where the welded parts are arranged in a row but also the case where the welded parts are arranged so as to form a zigzag shape, a dotted shape, a belt shape, etc. “Accommodating powder, liquid, solid agent” means accommodating any one or more of these, and “accommodating oxygen absorber, desiccant, oxygen-absorbing sheet, moisture-absorbing sheet” It means that any one or two or more of these are accommodated.
[0005]
DETAILED DESCRIPTION OF THE INVENTION
Embodiments of the present invention will be described below in detail with reference to the drawings illustrating embodiments of the present invention.
FIG. 1 shows an embodiment of the present invention (a multi-chamber container according to claim 1). In FIG. 1, 2 is a film constituting a chamber 4 for containing a liquid agent, 6 is a film constituting a chamber 8 for containing a powder agent and the like, 10 is a covering section 11 and a desiccant 16 covering the chamber 8, It is a film constituting the chamber 14 composed of the auxiliary agent containing section 12 containing the oxygen scavenger 18. That is, the chamber 14 is divided into two by the non-sealing partition portion 21 in which the welding portions 19 and the non-welding portions 20 are alternately arranged, one of which forms the auxiliary agent containing section 12 and the other of which forms the covering section 11. ing. The two zones 11 and 12 can communicate with each other through the gap S of the non-welded portion 20 as shown in FIG. The covering section 11 corresponds to a so-called object storing chamber covering section that covers a storing chamber for storing a powder agent, a liquid agent, a solid agent, etc., and the auxiliary agent storing section 12 is an oxygen scavenger, a desiccant, The chamber 14 formed of the covering section 11 and the auxiliary agent storage section 12 corresponds to a space portion according to the first aspect.
[0006]
A liquid agent is sealed in the chamber 4 and a mouth portion 22 is attached. A powder agent is sealed in the chamber 8. The chamber 8 is formed by welding the peripheral edges of two stacked films 6. That is, the film 6 is a multilayer film of an outer layer 26 made of polyethylene (hereinafter abbreviated as PE) and an inner layer 28 made of a mixed resin of PE and polypropylene (hereinafter abbreviated as PP) as shown in FIG. Yes, two multilayer films are welded at the periphery to form the chamber 8.
[0007]
On the other hand, the chamber 4 is constituted by the film 6 which is a multilayer film extending downward and being welded. That is, two multilayer films are overlapped and the peripheral edge thereof is welded, and the intermediate portion is welded in a lateral direction so that the strength is lower than that of the peripheral edge, thereby forming a weak seal portion 30 as a partitioning means. The chamber 8 and the chamber 4 are formed with this as a boundary.
[0008]
The chamber 14 composed of the covering section 11 and the auxiliary agent containing section 12 is formed by welding the peripheral edges of the two laminated films 10 and dividing the middle section into two by a lateral non-sealing partition section 21. Is done. That is, as shown in FIG. 1 (d), the film 10 is a multilayer film in which the inner layer 34 is PE and the outer layer 36 is a moisture-impermeable and gas-impermeable barrier film. As the barrier film, for example, polyethylene terephthalate ( (Hereinafter abbreviated as PET), and a triple layer of polyvinylidene chloride and PE, or a triple layer of PET and polyvinyl alcohol-deposited silica film and PE. Then, the two multilayer films are arranged so as to cover the chamber 8 so that there is a surplus above, the left and right peripheral edges and the upper peripheral edge are welded to each other, and the lower peripheral edge is a weak seal portion as shown in FIG. The non-sealing partition portion 21 is welded so as to be superimposed on the upper portion 30, and in the middle portion thereof, as shown in FIG. 1 (a), the welding portions 19 and the non-welding portions 20 are alternately arranged in the lateral direction. The covering section 11 and the auxiliary agent containing section 12 are formed with this as a boundary. The covering section 11 and the auxiliary agent storage section 12 are completely blocked from the outside air, but can communicate with each other through the non-welded portion of the non-sealing partition portion 21. Reference numeral 32 denotes a suspension hole formed at the upper end of the multi-chamber container.
[0009]
The gap between the non-welded portions 20 is moved to the adjacent coating section 11 by an auxiliary agent (including an oxygen-absorbing sheet, a water-absorbing sheet, etc.) such as a desiccant and an oxygen scavenger enclosed in the auxiliary agent storage section 12. The size is determined to be impossible. When the multilayer film is welded, a desiccant 16 and an oxygen scavenger 18 are enclosed in the auxiliary agent storage area 12. As the desiccant, for example, silica gel, zeolite, a silica gel molded product, an oxygen scavenger and the like are used. As the oxygen scavenger, commercially available products such as “AGELESS (registered trademark)” manufactured by Mitsubishi Gas Chemical Co., Inc., oxygen scavengers using amorphous copper, and the like can be used.
[0010]
Instead of the desiccant 16 and the oxygen scavenger 18 in the auxiliary agent storage area 12, a moisture absorbent sheet 38 or an oxygen absorbent sheet 40 may be arranged as shown in FIG. As an arrangement method, the sheets 38 and 40 may be fixed to the film 10 by welding or bonding as shown in FIG. In addition, the water-absorbing sheet 42 and the oxygen-absorbing sheet 44 chopped as shown in FIG. There is an advantage that the total surface area of the sheets 42 and 44 can be increased. Furthermore, the film 10 itself can be a moisture-absorbing sheet or an oxygen-absorbing sheet. For example, as a component constituting the moisture absorbing layer of the moisture absorbing sheet, Dry Keep (registered trademark) manufactured by Sasaki Chemicals Co., Ltd. is used as a component constituting the oxygen absorbing layer of the oxygen absorbing sheet. Oxygard (0XYGUARD) (registered trademark) manufactured by Seikan Co., Ltd. can be suitably used.
[0011]
In the welding of each part, the welding temperature is highest in the peripheral part of the chamber 8, the chamber 4 and the peripheral part of the chamber 14, and is about 170 to 200 ° C., and the weak seal part 30 is lower than this, about 110 to 130 ° C. Furthermore, the welded part of the film 6 and the film 10 and the welded part of the non-sealing partition part 21 are welded at 165 to 215 ° C. which is substantially the same as the peripheral part of the chamber 8, the chamber 4 and the peripheral part of the chamber 14. The
[0012]
In the embodiment configured as described above, the film 10 constituting the auxiliary agent containing section 12 and the covering section 11 enclosing the desiccant and the oxygen scavenger is a moisture impermeable and gas impermeable barrier film. As the film 6 constituting the chamber 8 is used, the outer layer is composed of a moisture permeable and gas permeable multilayer film composed of PE and the inner layer composed of a mixed resin of PE and PP. Can efficiently dry the powder and prevent oxidation of easily oxidizable drugs. Moreover, since the auxiliary agent storage area 12 which accommodates a desiccant and a deoxygenating agent is provided separately from the coating area 11 which directly covers the chamber 8, the desiccant etc. are accommodated in one conventional space portion. Compared to the above, since the desiccant is well organized and the desiccant does not move greatly, the desiccant does not overlap the chamber 8 containing the powder and is convenient. In addition, it is also possible to accommodate a desiccant, a deoxygenating agent, a moisture-absorbing sheet, an oxygen-absorbing sheet, or these together in both the auxiliary agent-accommodating zone 12 and the covering zone 11. Furthermore, if a transparent film is used as the films 6 and 10, the internal state can be visually observed. Then, by applying a certain pressure to the chamber 4 with a finger or the like, the weak seal portion 30 is peeled off, the chamber 4 and the chamber 8 are communicated, and the liquid agent and the powder agent are mixed and dissolved in an aseptic state.
[0013]
Examples of the powders in the above examples include hygroscopic, oxidizable and heat-denaturing substances such as antibiotics, anticancer agents, steroids, thrombolytic agents or vitamins, and these solutions or solutions as liquid agents Diluents such as physiological saline, glucose solution, and distilled water for injection can be mentioned. Some powdered antibiotics must be dissolved in an alkaline solvent such as sodium carbonate or other solubilizing agents before being dissolved in the lower liquid, but in such cases, An injection port (not shown) for mixing a solvent or the like is provided in the chamber containing the powder agent.
[0014]
As the film 6, in addition to the multilayer film described in the above examples, it is also possible to use a single layer or a multilayer film by a combination of one or more selected from PE, PP and a mixed resin thereof, preferably A two-layer film in which the inner layer of the film 6 is a mixed resin of linear low density polyethylene (hereinafter abbreviated as LLDPE) and PP and the outer layer is LLDPE can be used. The film 10 may be a single-layer or multi-layer sheet of polyvinylidene chloride, PET, an aluminum processed film, an ethylene vinyl alcohol copolymer (EVOH), or a silica-deposited film. When the film 6 and the film 10 are directly welded, at least the film 10 is a multilayer film in order to improve the welding, and the material of the innermost layer of the film 10 and the material of the outermost layer of the film 6 or the film 6 are the same. It is desirable to do. For example, when the outermost layer of the film 6 is LLDPE, it is desirable to use LLDPE for the innermost layer of the film 10.
[0015]
In the above embodiment, the powder agent is enclosed in the chamber 8 covered with the film 10, and the liquid is enclosed in the chamber 4 not covered with the film 10. However, depending on the purpose, the powder agent is used as the liquid agent, and the liquid agent is used as the powder agent. It is also possible to enclose instead of.
Examples of encapsulating a liquid agent in a chamber covered with the film 10 and encapsulating a powder agent in another chamber include, for example, oxidizable substances such as amino acid preparations to which cysteine or tryptophan is added as a liquid agent. Examples thereof include sugars, electrolytes, and mixtures thereof. In this case, only the oxygen scavenger is sealed in the auxiliary agent storage area 12. As an example in which a liquid agent is sealed in the chamber 8 covered with the film 10 and another liquid agent is sealed in another chamber, for example, the oxidizability of an amino acid preparation or a vitamin preparation added with cysteine or tryptophan as the former liquid agent, respectively. The latter liquid agent includes a sugar / electrolyte solution.
[0016]
As another example, an easily oxidizable substance such as a fat emulsion is used as the former solution, and a sugar / electrolyte solution is used as the latter solution.
Furthermore, it is also possible to enclose a solid agent in one of the chambers and a liquid agent in the other chamber. Furthermore, examples of the powders, liquids, and solids include various other nutrients and therapeutic agents that are administered intravenously or enterally (intratubes, orally).
Moreover, it is also possible to use only one of the desiccant and the oxygen scavenger enclosed in the auxiliary agent storage area 12 as necessary. Further, an aluminum processed film may be used for a part or all of the film 10 to shield the inside. In addition, as for the aluminum processing film used for the film 10, the one part or all part may be peelable as needed at the time of use.
[0017]
Although the said Example is an example of the 2 chamber container which encloses a liquid agent and 1 type of powder agent, it is applicable also in 2 or more chambers. For example, it is possible to provide a plurality of chambers for enclosing a powder agent, a solid agent, a liquid agent, or the like in the coating section 11 covered with the film 10 or a plurality of chambers not covered with the film 10. Moreover, although the said Example divided the chamber 14 up and down with the non-sealable partition part 21, it is also possible to partition the chamber 14 into right and left with the non-sealable partition part of an up-down direction. It is also possible to provide a plurality of non-sealing partitions and divide the chamber 14 into two or more.
[0018]
In the above embodiment, the weak seal portion 30 is formed by a so-called direct welding method in which the inner surfaces of the two films 10 constituting the chamber 8 are directly welded to each other. You may carry out by what is called a multilayer insert film clamping welding system which welds in the state which pinched | interposed the multilayer insert film, and forms a weak seal part. FIG. 2 shows an example using a two-layer insert film. In this case, 48 is a film constituting the chamber 8 and is a single layer film or a multilayer film, 50 is a film having a high thermal adhesive force with respect to the film 48 or the innermost layer of the film 48, 52 is a film 48 or It is a sheet having a weak thermal adhesive force with respect to the innermost layer sheet of the film 48, and a weak seal portion 54 is formed.
[0019]
For example, when the film 48 is a single layer film of PE or PP, 50 is the same PE or PP sheet, and 52 is a mixed resin of PE and PP. In this example, two films 48 are overlapped and the periphery is welded to form a bag. Instead, a tube-shaped film is used, a hole is formed in the middle portion, and sheets 50 and 52 are inserted therefrom. Then, after that, it is possible to form a weak seal portion by welding while pressing from the outside of the tubular film.
[0020]
FIG. 3 shows another embodiment of the present invention (a multi-chamber container according to claim 2). In addition, about the part which does not require a change with the said Example, the same number is attached | subjected and detailed description is abbreviate | omitted (the same is hereafter). The chambers 4 and 8, the covering section 11, the weak seal section 30 and the non-sealing partition section 21 are configured in the same manner as in the above embodiment, but the auxiliary agent storage section 12 also serves as the hanging section 56 at the same time. This is different from the previous embodiment. That is, the hanging part 56 is welded with the peripheral edges of the left and right and upper parts of the laminated film 10 and the peripheral edge of the hanging hole 60 provided in the vicinity of the center part, and the lower part by the non-sealing partition part 21. It is made to adjoin the covering section 11. The internal space of the hanging portion 56 forms the auxiliary agent accommodating section 12 and is cut off from the outside by the welded portion on the peripheral edge, but is communicated with the covering section 11 through the gap of the non-sealing partition portion 21. The suspending portion 56 is configured by the multilayer film 10 constituting the covering section 11 extending upward, and the periphery thereof and the periphery of the suspension hole 60 being welded. A desiccant 16 and an oxygen scavenger 18 are enclosed in the auxiliary agent storage area 12 which is an internal space of the hanging portion 56. Instead of this, a moisture absorbent sheet or an oxygen absorbent sheet may be enclosed, or these May be enclosed together, or the suspended portion 56 may be configured using a film having a water absorbing layer or an oxygen absorbing layer therein. According to the present embodiment, there is an advantage that the space of the hanging portion can be effectively utilized.
[0021]
FIG. 4 shows still another embodiment of the present invention (a multi-chamber container according to claim 3). A chamber 66 composed of an object accommodation area 62 and an auxiliary agent accommodation area 64 is adjacent to the chamber 4 made of the film 2 via the weak seal part 30, and the chamber 66 is arranged via the non-sealing partition part 21. It is divided into two sections 62 and 64, and both sections can communicate with each other through a gap in the non-sealing partition portion 21. In the auxiliary agent storage area 64 and the object storage area 62, the film 2 on both the front and rear sides constituting the chamber 4 extends upward, the right and left and upper peripheral edges are welded, and the intermediate portion is 2 by the non-sealing partition 21. Divided and configured. The auxiliary agent storage area 64 and the object storage area 62 are covered with a multilayer film 68 similar to the film 10 and are located in the space 70. The desiccant 16 and oxygen scavenger 18 are enclosed in the auxiliary agent storage area 64. Alternatively, a moisture-absorbing sheet or oxygen-absorbing sheet may be encapsulated, or these may be encapsulated together. Alternatively, the auxiliary agent storage area 64 may be configured by using a film having a water absorption layer or an oxygen absorption layer.
[0022]
FIG. 5 shows another embodiment of the present invention (a multi-chamber container according to claim 4). The front and rear films constituting the auxiliary agent containing section 64 (those in which the film 2 constituting the chamber 4 extends upward) are brought close to each other to make the inner space flat, and further, the film extends upward to connect the connecting portion 72. The upper end portion of the film is welded together with the film 68. The same as the multi-chamber container shown in FIG. 4 except that the auxiliary agent storage section 64 is flat and the upper end of the film forming the auxiliary agent storage section 64 is connected to the film forming the space 70. It is.
[0023]
The chamber located in the space covered with the moisture-impermeable and gas-impermeable barrier film of each of the above embodiments contains hygroscopic or easily oxidizable powders, liquids, solids and the like. In the said Example, although the adjuvant storage area 64 and the target object storage area 62 are comprised by the film which followed the film which comprises the chambers 4 and 8, you may comprise by joining a separate film. The same applies to the chamber 4 and the chamber 8.
Although several embodiments of the present invention have been described above, the present invention is not limited to such embodiments, and can of course be implemented in various modes without departing from the gist of the present invention. It is.
[0024]
【The invention's effect】
Since this invention is comprised as mentioned above, there exists an effect described below.
According to the multi-chamber container according to claim 1, the inside of the space part covered with the moisture impermeable and gas impermeable barrier film or the room containing the medicine is divided by the non-sealing partition part. Since the desiccant, oxygen scavenger, moisture absorbent sheet, oxygen absorbent sheet, etc. are enclosed in the compartment, the desiccant etc. is blocked by the non-sealing partition, and inside the compartment containing the adjacent medicine etc. Therefore, there is an advantage that the packaging of the multi-chamber container is not bulky. In addition, since the desiccant etc. is enclosed in the room containing the medicine, etc., there are less restrictions on the accommodation location and containment compared to the conventional example in which the desiccant etc. is enclosed in the space covered with the barrier film. There is an advantage that the degree of freedom in selecting a location is increased.
According to the multi-chamber container of claim 2, there is an advantage that the space of the hanging portion can be effectively utilized.
According to the multi-chamber container according to claims 3 to 5, since the desiccant or the like is directly enclosed in the chamber for storing the medicine or the like, the effect of preventing moisture absorption or preventing oxidation is great.
According to the multi-chamber container of claim 7, since the barrier film and the film constituting the chamber are composed of a film having a moisture absorption layer and an oxygen absorption layer, there is an advantage that the multi-chamber container itself becomes compact. .
[Brief description of the drawings]
FIGS. 1A to 1F are a front view, a longitudinal sectional view, an A section enlarged sectional view, a B section enlarged sectional view, a C section enlarged sectional view, and a D figure enlarged sectional view showing an embodiment of the present invention. , (G) to (h) are partial cross-sectional views showing modifications of the embodiment.
FIG. 2 is a partially enlarged sectional view showing a modification of the embodiment.
FIGS. 3A to 3C are a front view, an EE sectional view, and a partially enlarged sectional view showing another embodiment of the present invention.
4A and 4B are a front view and a longitudinal sectional view showing still another embodiment of the present invention.
FIGS. 5A to 5C are a front view, a longitudinal sectional view, and a partially enlarged sectional view showing another embodiment of the present invention.
[Explanation of symbols]
2 Film 4 Chamber 6 Film 8 Chamber 10 Film 11 Covering area (covering area for object storage room)
12 Auxiliary agent accommodation zone 14 Chamber 16 Desiccant 18 Deoxygenating agent 19 Welding part 20 Non-welding part chamber 21 Non-sealing partition part 30 Weak sealing part 38 Moisture-absorbing sheet 40 Oxygen-absorbing sheet 54 Weak sealing part 56 Hanging part 62 Object storage area 64 Auxiliary agent storage area 66 Room 68 Film 70 Space

Claims

A plurality of chambers for accommodating powder agent, liquid agent, and solid agent are formed with a flexible film, and a peelable seal portion is included as a means for partitioning adjacent chambers in a sealed state, and the plurality of chambers are further included. In a multi-chamber container in which one or two or more chambers are covered with a moisture-impermeable and / or gas-impermeable film to form a sealed space portion, the space portion is a welded portion and a non-welded portion. there was partitioned across the single or plurality of non-occlusive partition part which is to be placed in continuous alternately, powders one segment in the case in which a non-occlusive partition section singular, solutions, and the object storage chamber coating ku covering the chamber for accommodating the solid agent, deoxygenating agent and the other sections, desiccants, oxygen-absorbing sheet, and the auxiliary agent storage Ward for housing the moisture absorbent sheet, more When a non-sealing partition is provided The adjuvant accommodating Zone is divided into a plurality oxygen scavenger Te, desiccants, oxygen-absorbing sheet, and can accommodate a moisture absorbent sheet, and each partition can communicate with each other and through the gap of the non-weld portion A multi-chamber container characterized by that.

2. The multi-chamber container according to claim 1, wherein a suspension part for suspending the multi-chamber container itself is integrally formed in the auxiliary agent storage area.

A plurality of chambers for accommodating powder agent, liquid agent, and solid agent are formed with a flexible film, and a peelable seal portion is included as a means for partitioning adjacent chambers in a sealed state, and the plurality of chambers are further included. In a multi-chamber container in which one or more chambers are covered and sealed with a moisture-impermeable and / or gas-impermeable film, the moisture-impermeable and / or gas-impermeable film the covered Ru chamber is only one room, and divided transversely by single or multiple non-occlusive partition portion which is adapted unwelded portion and the welding portion of the chamber is arranged continuous with the alternate, non-singular When a sealing partition is provided, one section is an object storage section that contains powder, liquid, and solid agents, and the other section is an oxygen scavenger, desiccant, oxygen-absorbing sheet, and moisture. Auxiliary storage area for storing the absorbent sheet A plurality of non-occlusive In the case where the partition portions and the provided auxiliary agent accommodating Zone is divided into a plurality oxygen scavenger, a desiccant, an oxygen absorbent sheet, and can accommodate a moisture absorbent sheet, and the The multi-chamber container characterized in that the sections can communicate with each other through a gap between the non-welded portions.

4. The multi-chamber container according to claim 3, wherein the front and rear flexible films constituting the auxiliary agent containing section are brought close to each other so as to be in close contact with each other, and an oxygen scavenger, a desiccant, and oxygen absorption enclosed between the films. The peripheral portion of the adhesive sheet and the moisture-absorbing sheet can communicate with the adjacent object storage area through the gap of the non-sealing partition, and one end of the auxiliary agent storage area directly covers the chamber. A multi-chamber container connected to a gas-impermeable film.

5. The multi-chamber container according to claim 1, further comprising: a non-sealed chamber that is covered with a moisture-impermeable and / or gas-impermeable film among the plurality of chambers. A multi-chamber container in which a powder agent, a liquid agent, and a solid agent having hygroscopicity and / or oxidization property are accommodated in an object accommodation area in a room divided by a sex partition.

The multi-chamber container according to any one of claims 1 to 5, wherein an oxygen-absorbing sheet and a moisture-absorbing sheet are formed in an internal space formed by a moisture-impermeable and / or gas-impermeable film. A multi-chamber container in which either one or both are sealed in a state of being connected to the film forming the internal space.

The multi-chamber container according to any one of claims 1 to 6, wherein the moisture impermeable and / or gas impermeable film and all or one of the films constituting the chamber covered with the film. The part is a film having a water absorbing layer and / or an oxygen absorbing layer, and absorbs moisture and / or oxygen in the interior space and the chamber formed by the moisture impermeable and / or gas impermeable film. Multi-chamber container.