JP3545290B2 - Reishi charcoal and its uses - Google Patents

Description

[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention belongs to the technical fields of food additives, skin cleansers, cosmetics, dentifrices and the like obtained by processing Ganoderma lucidum.
[0002]
[Prior art]
Conventionally, as a so-called "medicinal charcoal", it has been known to carbonize trees and bamboo plants and use them to improve allergic diseases and renal disorders. In addition, as disclosed in JP-A-5-105616. In addition, it is also known that dentifrice mixed with black-burned eggplant adsorbs and discharges plaque, tartar, and bacteria.
It is also known to extract "carbide" from petroleum and use it as "medicated charcoal" to improve chronic renal failure and uremic disease.
On the other hand, it has been known that the components of Ganoderma lucidum are extracted, and the extracted components are used as Chinese herbal medicines and health foods. It provides a method for cultivating ganoderma, which absorbs nutrients and absorbs minerals, especially rare selenium.
It has not yet been known that mushrooms, especially reishi, are carbonized into "medicated charcoal".
[0003]
[Problems to be solved by the invention]
However, conventional "medicinal charcoal" always causes constipation when ingested, and thus has a problem that it must be used in combination with a laxative, and is particularly unsuitable as a food additive or food additive. In addition, the efficacy is good for allergy, atopy, rheumatism, renal disorder, but is uncertain.
In addition, petroleum-derived medicinal charcoal is likely to cause constipation, loss of appetite, vomiting, and abdominal swelling to irritate the affected area, and is especially used for elderly people, pregnant women, and children due to these side effects. There was a problem that it was not possible.
The present invention has been made in view of the above problems, an object of the present invention is to provide a charcoal of Ganoderma lucidum having excellent effects such as improving blood circulation, and is particularly safe for the human body and alone. Carbide food additive that does not cause constipation even when used, a skin cleanser that is safe for the human body and improves blood circulation and thickens hair, a cosmetic agent that is safe for the human body and improves blood circulation such as facial skin, and Another object of the present invention is to provide a dentifrice that is safe for the human body and improves the blood circulation of the gums.
[0004]
[Means for Solving the Problems]
In order to solve the above problems, the invention according to claim 1 is: After inoculating the raw wood inoculation hole and cultivating, the raw wood is buried in the cultivation bed using Asama sand and cultivated. Reishi is a carbide of Ganoderma, which is made from calcium and phosphorus as its main components, and contains germanium, selenium, and silicon for a long time at a high temperature and carbonized almost in anoxic condition. It can be used.
In order to solve the above problems, the invention described in claim 2 is After inoculating the raw wood inoculation hole and cultivating, the raw wood is buried in the cultivation bed using Asama sand and cultivated. Addition of foods mainly composed of charcoal of Ganoderma lucidum, which is made of Ginkgo biloba containing calcium, phosphorus and germanium, selenium and silicon for a long time at high temperature and almost in anoxic condition. It is a food additive that is safe for the human body and has various effects without constipation when used alone.
In order to solve the above problem, the invention according to claim 3 is: After inoculating the raw wood inoculation hole and cultivating, the raw wood is buried in the cultivation bed using Asama sand and cultivated. Skin made of Ganoderma lucidum, which contains calcium and phosphorus as its main components and contains germanium, selenium, and silicon for a long time at a high temperature and carbonized almost in anoxic condition, as a detergent component It is a cleansing agent that is used to increase blood flow and thicken the hair when used.
In order to solve the above problems, the invention according to claim 4 is: After inoculating the raw wood inoculation hole and cultivating, the raw wood is buried in the cultivation bed using Asama sand and cultivated. Cosmetic mixture of Ganoderma lucidum, which contains calcium and phosphorus as its main components and contains germanium, selenium, and silicon for a long time at a high temperature, and is almost anoxic, and is blended with a cosmetic ingredient. Because it is an agent, it is a cosmetic agent that improves blood circulation of the facial skin.
In order to solve the above problems, the invention according to claim 5 is After inoculating the raw wood inoculation hole and cultivating, the raw wood is buried in the cultivation bed using Asama sand and cultivated. A dentifrice in which the ginseng containing calcium, phosphorus as a main component and germanium, selenium, and silicon is heated to a high temperature for a long time and carbonized in an almost oxygen-free state is mixed with the dentifrice component as a dentifrice component. Because it is an agent, it is a dentifrice that improves the blood circulation of the gums.
[0005]
BEST MODE FOR CARRYING OUT THE INVENTION
Hereinafter, preferred embodiments of the present invention will be described in detail.
First, the reishi to be carbonized (scientific name: GANODERMA LUCIDUM) used in the present example is a reishi obtained by the cultivation method disclosed in the above-mentioned Japanese Patent Publication No. 3-70450. The outline of the reishi is described below.
According to the reishi cultivation method described above, a fungus hole is opened in the double-sided cross section of the cut log and the surrounding area, the inoculated hole is inoculated into the inoculated hole, horizontal culture is performed for about one month, and then the vertical culture is performed. After about two months, the raw wood is buried in a buried bed for culture using Asama sand, and at the same time, the raw wood is further covered with sand of about 2 cm in thickness and cultivated. In addition to the fact that the hypha is already vigorous and has good growth during the culture period up to the implantation of Asama sand, Asama sand has a very low bacterial count due to its volcanic nature, and the growth of the hypha is not hindered by various bacteria. Reishi can absorb nutrients and minerals accumulated deep inside the wood, especially selenium, which is rare and valuable.
[0006]
The ginseng obtained by the above cultivation method was dried and analyzed, and the composition table is shown in [Table 1]. The unit of [Table 1] is% by weight (mg) based on 100 g of dried ginseng. The approximate composition ratio of is 80.37 g of carbon, 2.05 g of hydrogen, 2.50 g of oxygen, and 15.08 g of ash. The composition table in [Table 1] is also a breakdown of ash rich in many mineral components.
The numerical values are average values of 20 samples, and the degree of variation was a numerical value within approximately 10% of the average value.
The characteristic of the components in [Table 1] is that The breakdown of ash contains germanium, selenium, and silicon with calcium and phosphorus as main components, The components of germanium, selenium, and silicon are particularly large as compared with mushrooms, and since these components are trace elements, they are harmless to the human body and extremely effective in health.
[0007]
Next, a method of carbonizing the reishi obtained by the above cultivation method will be described.
First, 25-30 kg of Reishi is put in a container lined with Asama stone inside stainless steel, and the lid is closed so that air does not enter from the outside, that is, at a temperature of 120-1000 ° C. in an almost oxygen-free state so as not to burn. The carbonization is performed by heating for 6 to 12 hours continuously to form a so-called “black burn”.
The reishi char obtained as described above has a slightly reduced ratio of hydrogen and oxygen to 80.99 g of carbon, 1.67 g of hydrogen, 2.08 g of oxygen, and 15.26 g of ash. There is almost no difference from the composition table of [Table 1]. In particular, even in 20 samples of carbide of Reishi, germanium is in the range of 1.176 to 0.965 mg, the average is 1.077 mg, and selenium is 2.03-1. The average is 1.86 mg in the range of 60 mg, and the average is 14.50 mg in the range of 15.81 to 13.11 mg of silicon. The charcoal of the reishi thus obtained is useful as a medicinal charcoal, and the so-called medicinal charcoal, which is mainly medicinal, is a food additive, a skin cleanser, a cosmetic, a dentifrice, etc. Can be used for various applications.
[0008]
Next, the effects of each use will be described.
First, as a first embodiment, a preferred example in the case where the charcoal of Reishi is used alone as a food additive or a food additive will be described below.
[Example 1]
(1) Food additive
The charcoal obtained by the above-described method was used as a powder to analyze the effect of use as a food additive by the following two inspection methods (effect confirmation 1 and 2) to confirm the effect.
(1) -1 (Effect confirmation 1)
Administration method: The subjects were 98 patients (31 males and 67 females) who had one or more illnesses and were hospitalized. 78 and 20 comparative patients were administered charcoal of starch (placebo: mimic).
The administration period was 6 weeks, and the dose was 0.25 g of powder at a time, orally administered 2-3 times a day.
The test contents were observed for changes in capillaries (microvessels), urine volume, degree of decrease in circumference (swelling) of the ankle of the foot (5 cm in the inner malleolus), presence of subjective symptoms, and the like.
Administration results: Table 2 shows the test contents.
[0009]
By expanding and observing the movement of blood flow in the capillaries of the fingertip nail epithelium, which are microvessels, it is possible to continuously and dynamically measure the diameter, blood velocity, flow rate, blood vessel density, etc. of the capillaries. be able to. This has already been provided by the present inventors as Japanese Patent Application No. 10-125355, but as shown in FIG. 12, the nail epithelium at the boundary between the fingernail and the skin is enlarged under a microscope. This is because the skin is thin and the capillaries can be seen through, and the movement of blood, especially red blood cells (hemoglobin), can be observed. Based on the measurement results, it can be used for the discovery and treatment of many diseases, for example, many diseases such as heart disease, burns, hepatitis, leukemia, anemia, bronchial asthma, diabetes, rheumatism, pneumonia, and preeclampsia. It is known that it can be used for discovery and treatment.
[0010]
In [Table 2], the larger the "number of microvessels", the better the blood circulation tends to be. However, the ratio of the increase in the number of microvessels per 1 mm of the width of the predetermined location is increased to 0.4 in Comparative Example 1. On the other hand, in the first embodiment, the increase is 0.9, and the rate of increase is clearly large. Regarding the “red blood cell agglutination degree”, the blood flow state was better when the degree of agglutination was smaller, and the blood flow state was better in Comparative Example 1 whereas it was lower in Example 1 and the blood flow state was better. I can ask. The “ratio of blood vessel thickness” is considered to be abnormal if the blood vessel thickness on the exit side becomes 3 or more times the blood vessel thickness on the introduction side of the curved blood vessel of the nail epithelium. The smaller the ratio, the better. However, in Comparative Example 1, the ratio does not decrease so much, whereas in Example 1, the ratio largely decreases from 36% to 21%.
The "24 hour urine output" is said to be preferably about 1500 ml to 2000 ml in patients with hypertension, angina pectoris and renal failure, and it is not so much changed in comparative example 1, but 2000 ml in example 1. Is approaching.
"Swelling" measures the thickness (circumference) of the foot at 5 cm above the inner ankle of the foot, and measures the degree of "swelling." In Comparative Example 1, 3 out of 20 15% of people In contrast to the swelling, in Example 1, 21 out of 78 persons, 27% of the persons, had swelling.
Note that the P value is a significant difference serving as a statistical standard.
Although improvement in blood circulation could be confirmed by such physical changes, the subjective symptoms were almost the same in Comparative Example 1 as compared with those in Comparative Example 1 even though the subjective symptoms were ingested by ingestion of Example 1 from the subjective symptoms. In 1, the number decreased from 28 to 17 people. Specific cases of subjective symptoms improved by the ingestion of Example 1 were 21 for hypertension, 16 for angina, 33 for hyperlipidemia, 6 for diabetes, 5 for cerebral infarction, and chronic hepatitis. There were reports of improvement in cirrhosis in 11 cases and renal failure in 8 cases (some people have several types of illness, and others have multiple answers).
[0011]
(1) -2 (Effect confirmation 2)
Administration method: The subjects were patients with one or more illnesses who were hospitalized, and 76 were randomly assigned to 55 recipients of the charcoal of the reishi of Example 1 and charcoal of starch as Comparative Example 1. The effect of use was observed for 21 (placepo) users.
A: Breakdown of the administration groups in Example 1 (there are duplicates for those with disease)
55 patients (outpatient), 28 men, 27 women, average 65 years ± 6 years
20 cases of renal failure
Eight cases of ulcerative colitis
5 cases of irritable enteritis
Hypertension 31 cases
16 cases of angina
B: Breakdown of the administration groups of Comparative Example 1 (there are duplicates for those who have the disease)
21 patients (outpatient), 11 men, 10 women, average 68 years ± 5 years
7 cases of renal failure
Ulcerative colitis 3 cases
Irritable enteritis 2 cases
Hypertension 8 cases
5 cases of angina
The administration period was 16 weeks, and the dose was 1 g of powder at a time, twice a day by oral administration.
Before the administration of the charcoal of Reishi and the placebo of the comparative example, the test subjects recorded their subjective symptoms and signs, performed blood tests at the same time, and compared the changes after administration. However, all patients continued to take their current medication.
[0012]
The results of this subjective symptom are shown in [Table 3]. In [Table 3], the administration group of Example 1 had a headache, dizziness, heavy head feeling, weakness, chest tightness compared to the administration group of Comparative Example 1. The rate of improvement in tinnitus, edema, stool frequency, urine volume, and blood pressure was superior.
The results of the blood test are shown in [Table 4]. In [Table 4], RBC (10,000 / mm ³ ) Is the amount of erythrocytes. The administration of Comparative Example 1 shows no change, whereas the administration of Example 1 shows an increase in the amount of erythrocytes. HB (g%) is the content of hemoglobin in Comparative Example 1. While the administration did not change, the administration of Example 1 increased the hemoglobin content, and the Ht (vol%) hematocto value was not changed by the administration of Comparative Example 1, whereas the Example No. 1 increased, and WBC (/ mm ³ The number of white blood cells of (1) is not changed by the administration of Comparative Example 1, but increases by the administration of Example 1, and the blood condition is improved.
Next, it is better that the content of certain minerals in the blood is small, but the Mg (mg%) value of the magnesium content is different between the administration group of Example 1 and the administration group of Comparative Example 1. Although the value was not found, the value of k (mEq / L), which is the potassium content in 1 liter, was greater in the administration of Example 1 than in the administration of Comparative Example 1. In addition, the value of creatinine (one of the renal function tests) content of Cr (mg%) was not changed by the administration of Comparative Example 1, but decreased by the administration of Example 1, and the nitrogen content in the blood was decreased. BUN (mg%), which is the content, also shows a greater decrease in the administration of Example 1 than in the administration of Comparative Example 1, and these values are improved.
Further, the test results of the plasma viscosity are shown in [Table 5]. It is clear that the degree of viscosity decrease in the administration of Example 1 was larger than that in the administration of Comparative Example 1, and the blood viscosity state was It has been improved and blood circulation has been improved.
[0013]
[Table 3] [Table 4] It can be said from the results of [Table 5] that the continuous oral administration of the Ganoderma lucidum of Example 1 for 16 weeks resulted in the patient's headache, dizziness, tinnitus, edema, urine volume, The improvement of subjective symptoms such as the number of defecations was remarkably improved, whereas no significant change was observed in the case of administration of placebo in Comparative Example 1. This is thought to be due to the fact that the Ganoderma lucidum of Example 1 absorbs and excretes K, Mg, BUN, Cr and the like in blood through the intestinal wall, thereby lowering the blood concentration. In addition, anemia, which is commonly seen in renal insufficiency, is improved along with improvement in kidney function.
For hypertension, plasma viscosity, water metabolism, and Na balance are very important, and it is considered that blood pressure stability is measured as renal function improves.
Although ulcerative colitis is an autoimmune disease, damage to the intestinal wall makes it easier for intestinal toxins to invade, causing more damage and worsening the disease. It is considered that the excretion repairs the large intestine and eliminates subjective symptoms.
In the case of irritable enteritis, it is considered that administration of the charcoal ganoderma of Example 1 adsorbs and excretes intestinal antigens, suppresses intestinal hypersensitivity reaction, and suppresses the occurrence of disease.
In addition, no adverse effects were observed except for the mild constipation of several persons by the continuous administration of Reishi charcoal carbide of Example 1 for 16 weeks.
[0014]
Next, as a second embodiment, a preferred example in which charcoal from Reishi is used for a hair-washing shampoo that is a skin cleanser and is also called a hair cosmetic is described below.
(2) -1 Hair wash shampoo (skin cleanser) (Example 2)
The powder of the carbide (black burnt) obtained by the above-described method is blended with the detergent component at the following ratio.
[Example 2]
Reishi Carbide (Black Roasted) 2W / W%
Sodium tetradecene sulfonate 10W / W%
Glycerin 2W / W%
Ethanol 2W / W%
Thickener 1W / W%
Silicon 0.5W / W%
Xanthan gum 0.5W / W%
Squalane 0.2W / W%
Sodium hyaluronate 0.1W / W%
Purified water 81.7W / W%
Total 100.0W / W%
The effect of use as a hair-washing shampoo (skin-detergent) having the above mixing ratio was analyzed by the following method to confirm the effect.
Administration method: 54 subjects, 30 hair shampoos (12 males, 18 females) randomly mixed with the ganoderma charcoal of Example 2 were used.
As Comparative Example 2, 24 shampoos (10 males and 14 females) were used in the same proportions as in Example 2 above, except that the charcoal (black roast) of Reishi was not used, but instead 83.7 W / W% of purified water. ).
The use period was 6 weeks, and the hair was washed (shampooed) once daily, and the washing time was about 5 minutes.
The measuring method is as follows: (1) Before and after washing, using a contact microscope, the diameters of the tips of the 20 hairs of the subject were measured, and the average value of the hair thickness was calculated [Table 6]. (2) The blood perfusion volume of the microvessels at four locations in the specified area was measured with a laser Doppler blood flow meter, and the average value was calculated [Table 7].
[0015]
The results are shown in [Table 6] and [Table 7], and the effect of use is analyzed.
In Table 6, the change in the thickness of the hair before and after the use of Example 2 shows almost no change with the use of the normal commercial shampoo of Comparative Example 2, but the charcoal of the reishi grass of Example 2 was changed. The person using the mixed shampoo was confirmed to have a tendency to thicken the hair.
In [Table 7], the change in microvascular blood flow of the scalp before and after use was greater in the group using the shampoo mixed with the charcoal of the reishi of Example 2 than in the group using Comparative Example 2. It was confirmed that the blood flow was large.
It is considered that this is due to trace elements of carbides of Reishi and far-infrared rays due to carbonization as one effect.
In the group using the shampoo of Example 2, no abnormalities such as redness, swelling, itching and irritation of the skin of the scalp and face were observed, and no abnormal irritation to the eyes was observed. No difference was observed even in comparison with Comparative Example 2.
In the above-mentioned Example 2, an example was described in which a skin cleansing agent, particularly a hair wash shampoo as a hair cosmetic, was used. However, as described below, the present invention is applied to other skin cleansing treatments, body soaps and the like. It was confirmed that the blood circulation was improved as in Example 2 even when the charcoal of the reishi of the present invention was mixed.
In Example 2, the charcoal (black burnt) of Ganoderma lucidum was 2 W / W%. However, the effect was not remarkable at 1 W / W% or less, and the detergency decreased at 10 W / W% or higher. The compounding ratio of the carbide (black firing) is preferably in the range of 1 to 10 W / W%.
[0016]
Similarly, as a third embodiment, a preferred example in the case where charcoal from Reishi is used as a skin cleanser and also in a treatment also called a hair cosmetic is described below.
(2) -2 Treatment (skin cleanser) (Example 3)
A powder of the powdered Ginseng charcoal (black burnt) obtained by the above-described method is added to a detergent component.
[Example 3]
Reishi Carbide (Black Roasted) 1W / W%
Rapeseed oil alcohol 10W / W%
Glycerin 4W / W%
Alkylamine 2.5W / W%
Nonionic surfactant 3W / W%
Silicon 1W / W%
Purified water 78.5W / W%
Total 100.0W / W%
The effect of using the above-mentioned composition ratio as a treatment was analyzed by the same method as in Example 2 to confirm the effect.
Administration method: Forty-seven subjects (24 males (10 males, 14 females)) were randomly treated with the reishi charcoal carbide of Example 3.
As Comparative Example 3, 23 treatments (9 males, 14 males) were performed in the same proportions as in Example 3 described above, except that the charcoal (black roast) of Ganoderma lucidum was not used, but instead purified water was 79.5 W / W%. Used for
The use period was 6 weeks, and the hair was washed once a day and then treated, and the use time was around 4 minutes.
The measurement method was as follows: before and after washing, the blood perfusion flow rate of the microvessels at four places in the specified area was measured with a laser Doppler blood flow meter, and the average value was calculated [Table 8].
[0017]
The results are shown in [Table 8] and the effect of use is analyzed.
In Table 8, the change in the microvascular blood flow of the scalp before and after the use was compared with the group using the comparative example 3 in the blood flow rate in the group using the treatment containing the reishi charcoal carbide of the present example 2. It was confirmed that there were many.
In the group using the treatment of Example 3, no abnormalities such as redness, swelling, itching and irritation of the skin of the scalp and face were observed, and no abnormal irritation to the eyes was observed. No difference was observed even in comparison with Comparative Example 2.
In Example 3, the charcoal (black burnt) of Reishi was 1 W / W%, but the effect was not remarkable at 0.5 W / W% or less, and at 10 W / W% or more, the treatment effect was reduced. The mixing ratio of the turf carbide (black burnt) is preferably in the range of 0.5 to 10 W / W%.
[0018]
(2) -3 Body soap (skin cleanser) (Example 4)
A powder obtained by blending a powder of the carbide (black burnt) obtained by the method described above in the following ratio.
[Example 4]
Reishi charcoal (black burnt) 0.3W / W%
Soap 24W / W%
Amphoteric detergent 3W / W%
Cleaning aid 4W / W%
Butylene glycol 3W / W%
Viscosity adjuster 1W / W%
Tourmaline 0.1W / W%
Peanut oil 0.3W / W%
Sodium hyaluronate 0.1W / W%
Purified water 64.2W / W%
Total 100.0W / W%
The effect of using the compounding ratio as a body soap (detergent for body skin) as described above was analyzed by the same method as in Example 2, and the effect was confirmed.
Administration method: Forty-nine subjects (27 males (11 males, 16 females)) randomly used body soaps (skin detergents) mixed with charcoal of Reishi from Example 4.
As Comparative Example 4, 22 people (9 males and 13 females) were not blended with charcoal (black roast) from Reishi at the blending ratio of Example 4 described above, but instead used 64.65 W / W% purified water instead of purified water. First name).
The use period was 6 weeks, the body was washed once with a body soap, and the use time was about 5 minutes.
The measurement method was as follows: before and after washing, the blood perfusion volume of the microvessels at four places in the defined area of the chest region was measured with a laser Doppler blood flow meter, and the average value was calculated [Table 9].
[0019]
The results are shown in [Table 9] and the effect of use is analyzed.
In Table 9, the change in the microvascular blood flow of the scalp before and after use was higher in the group using the body soap in which the charcoal of Ganoderma lucidum of Example 4 was blended in the cosmetic ingredient than in the group using Comparative Example 4. It was confirmed that the blood flow was higher in the case.
In the group using the body soap of Example 4, no abnormalities such as redness, swelling, itching and irritation of the skin of the body were observed, and no abnormal irritation to the eyes was observed. No difference was observed even in comparison with Comparative Example 4.
In Example 4, the charcoal (black burnt) of Reishi was 0.3 W / W%, but the effect was not remarkable at 0.1 W / W% or less. Since the amount is reduced, the compounding ratio of the charcoal (black burnt) of Reishi is preferably in the range of 0.1 to 10 W / W%.
[0020]
Next, as a fifth embodiment, a preferred example in the case where charcoal of Reishi is used as a cosmetic agent will be described below.
(3) Cleansing gel (cosmetic) (Example 5)
It is obtained by blending the powder of the carbide (black-fired) obtained by the method described above in the following ratio.
[Example 5]
Reishi Carbide (Black Roasted) 1W / W%
Triglycerite 38W / W%
Ester oil 19W / W%
Castor oil-based activator 18.5W / W%
Purified water 23.5W / W%
Total 100.0W / W%
The effect of use as a cleansing gel (cosmetic) having the above mixing ratio was analyzed by the following method to confirm the effect.
Administration method: Among the 54 subjects, 30 cleansing gels (all female) containing the charcoal of Reishi in Example 2 were randomly used.
As Comparative Example 5, 24 cleansing gels (all women) were used in which the blending ratio of the above Example 5 was not used, and instead, the charcoal (black roast) of Ganoderma lucidum was not used, but instead purified water was used at 24.5 W / W%. .
The use period was 6 weeks and used once every morning.
The measurement was performed by measuring the blood perfusion volume of the microvessels at four places in the specified area at the cheek region of the face with a laser Doppler blood flow meter and calculating the average value [Table 10].
[0021]
The results are shown in [Table 10] and the effect of use is analyzed.
In [Table 10], the change in microvascular blood flow in the skin of the cheek of the face before and after the use was compared with the group using Comparative Example 5 in the group using the cleansing gel mixed with the charcoal of Reishi in Example 5. It was confirmed that the blood flow was higher in.
This is also considered as one effect due to trace elements of carbides of Reishi and far infrared rays due to carbonization.
In the group using the cleansing gel of Example 5, no abnormalities such as redness, swelling, itching and irritation of the skin of the face were observed, and no abnormal irritation to the eyes was observed. No difference was observed even in comparison with Comparative Example 2.
In Example 4, the carbonized (black-burned) reishi was 1 W / W%, but at 0.5 W / W% or less, the effect was not remarkable, and at 10 W / W% or more, cleansing action on the skin (skin). Therefore, the compounding ratio of the charcoal (black burnt) of Reishi is preferably in the range of 0.1 to 10 W / W%.
[0022]
Next, as a sixth embodiment, a preferred example in the case where charcoal of Reishi is used as a dentifrice will be described below.
(4) Dentifrice (Example 6)
The powder obtained by blending the powder of the carbide (black burnt) obtained by the above-described method with the following ratio in the dentifrice component.
[Example 6]
Reishi Carbide (Black Roasted) 1W / W%
Calcium hydrogen phosphate (abrasive) 40W / W%
Glycerin (lubricant) 10W / W%
Sodium lauryl sulfate (foaming agent) 1W / W%
Carboxymethyl cellulose (adhesive) 1W / W%
Xylitol (flavoring agent) 1W / W%
Legal pigment (colorant) 0.1W / W%
Parabens (preservatives) 1W / W%
Purified water 44.9W / W%
Total 100.0W / W%
The effect of using the above mixture ratio as a dentifrice was analyzed by the following method to confirm the effect.
Administration method: 60 subjects (21 men, 39 women: those without disease such as hypertension, heart disease, hyperlipidemia, blood disease, kidney disease). The dentifrice of Example 6 described above, in which the charcoal of the reishi of Example 2 was randomly blended, was used for 30 persons (11 men and 19 women).
As Comparative Example 6, 30 dentifrices (10 males, 20 females) were prepared in which the mixture of Example 6 was not blended with the charcoal (black roast) of Reishi, but instead was 45.9 W / W% of purified water. First name).
However, as a site to be used for the test, the gum was a site where it was difficult to measure the state of blood flow. Therefore, changes in capillaries in the nail epithelium of the finger, which is almost the same site, were observed.
The test method was as follows. The dentifrices of Example 6 and Comparative Example 6 were imprinted on the finger nail epithelium, and the same operation as the brushing action was performed. , The diameter of the blood vessel entrance and exit, and the blood flow velocity) were observed and recorded, and the observation test was repeated for 5 days (once / day), and the results were averaged and the results were compared.
The target of the observation examination is the ring finger of the left hand (right-handed person) (the middle finger or the little finger when the ring finger is inconvenient), the finger is set at the same height as the heart in a sitting state, and the skin temperature 22 in a resting state. At a temperature of 体 25 ° C. and a body temperature of 36.5 to 37.2, the local area of the test object was a site free from damage or scar, and observed and inspected at about 9 pm every morning.
[0023]
The test results are shown in [Table 11] and the effect of use is analyzed.
In Table 11, the density of capillaries in the finger nail epithelium (number / mm) was not significantly changed in the administration group of Comparative Example 6, but increased in the administration group of Example 6. Blood circulation is improving.
As shown in FIG. 12, in the nail epithelium 2 at the lower edge of the nail 1, the capillaries 3 can be seen through, but the diameter of the import leg vessels of the import leg 4 into which the blood of the capillaries 3 flows is also the comparative example 6. Although there was no significant change in the administration group, the administration group of Example 6 was thicker and had better blood circulation.
Similarly, the export leg blood vessel diameter of the export leg 5 from which the blood of the capillary 3 flows out is not significantly changed in the administration group of Comparative Example 6, but is increased in the administration group of Example 6 and blood circulation is improved. ing.
Therefore, it can be confirmed that the blood circulation of the group using the dentifrice containing the carbide of Ganoderma lucidum of the present Example 6 would be better than that of the group using Comparative Example 6 also in the gums.
This is also considered as one effect due to trace elements of carbides of Reishi and far infrared rays due to carbonization.
In addition, in the group of persons who actually used the dentifrice of Example 6, the condition of the gums was no longer swollen such as swelling, and no abnormalities such as redness, swelling, itching and irritation were found on the gums. In this respect, no difference was observed even in comparison with Comparative Example 6.
In Example 6, the carbide (black burnt) of Reishi was 1 W / W%, but the effect was not remarkable at 0.5 W / W% or less, and the polishing action was reduced at 10 W / W% or more. The compounding ratio of the turf carbide (black burnt) is preferably in the range of 0.1 to 10 W / W%.
[0024]
The present invention is not limited to this embodiment as long as the features of the present invention are not impaired, and it is needless to say that the present invention may be used for those having improved blood circulation due to the charcoal of Ganoderma lucidum of the present invention.
[0025]
【The invention's effect】
According to the first aspect of the present invention, the reishi containing germanium, selenium, and silicon containing calcium and phosphorus as main components is heated to a high temperature for a long time and carbonized in an almost oxygen-free state. Since it is a charcoal of Reishi, it has various effects on food additives (additives), skin cleansing agents, cosmetics, dentifrices, etc. for the human body. According to the described invention, since it is a food additive containing the above charcoal of Reishi as a main component, it is safe for the human body and does not cause constipation even when used alone, resulting in hypertension, angina pectoris, and hyperlipidemia. The present invention according to claim 3, which has an effect on various diseases such as diabetes, diabetes, cerebral infarction, chronic hepatitis, and cirrhosis, and according to the invention of claim 3, a skin cleanser comprising the above-mentioned charcoal of Reishi in a detergent component. Therefore, blood flow increases by using According to the fourth aspect of the present invention, the hair is thickened, and the cosmetic is a cosmetic agent mixed with the above-mentioned charcoal of Ganoderma lucidum and a cosmetic ingredient. According to the invention described in Item 5, since it is a dentifrice containing the above charcoal of Reishi in a dentifrice component, it has an effect of improving blood circulation of gums.
[Brief description of the drawings]
FIG. 1 is a table of [Table 1] showing a component table of Reishi used in the present invention.
FIG. 2 shows the results of administration of Example 1 of the present invention and Comparative Example 1 [Table 2].
FIG. 3 is a table of [Table 3] showing changes in subjective symptoms of Example 1 of the present invention and Comparative Example 1.
FIG. 4 is a table of [Table 4] showing changes in blood tests of Example 1 of the present invention and Comparative Example 1.
FIG. 5 is a table of [Table 5] showing changes in plasma viscosity of Example 1 and Comparative Example 1 of the present invention.
FIG. 6 is a diagram of [Table 6] showing changes in hair thickness of Example 2 and Comparative Example 2 of the present invention.
FIG. 7 is a diagram of [Table 7] showing the effects of microvessels on the scalp on blood flow in Example 2 of the present invention and Comparative Example 2;
FIG. 8 is a diagram of [Table 8] showing the effects of microvessels on the scalp on blood flow in Example 3 of the present invention and Comparative Example 3;
FIG. 9 is a diagram of [Table 9] showing the effects of the microvessels of the body on blood flow in Example 4 and Comparative Example 4 of the present invention.
FIG. 10 is a chart of [Table 10] showing effects of microvessels on the skin of the face on blood flow in Example 5 of the present invention and Comparative Example 5;
FIG. 11 is a diagram of [Table 11] showing changes in capillaries in finger nail epithelium (gums) of Example 6 of the present invention and Comparative Example 6;
FIG. 12 is a schematic view of the nail and the nail epithelium, illustrating the state of capillaries in the nail epithelium.
[Brief description of reference numerals]
1 ... claw
2 ... Nail epithelium
3 Capillaries
4 ... Capillaries import leg
5 Capillary export leg

Claims (5)

After inoculating and inoculating the inoculation hole of the raw wood, the raw wood is cultivated by burying it in a buried bed for culture using Asama sand, and the ash is mainly composed of calcium and phosphorus germanium, selenium, and A charcoal of reishi, characterized in that the reishi containing silicon is carbonized in a high temperature over a long period of time and almost in an oxygen-free state. After inoculating and inoculating the inoculation hole of the raw wood, the raw wood is cultivated by burying it in a buried bed for culture using Asama sand, and the ash is mainly composed of calcium and phosphorus germanium, selenium, and A food additive characterized by comprising, as a main component, a charcoal of ganoderma, which is obtained by heating a silicon-containing ganoderma over a long period of time and carbonizing in a substantially oxygen-free state. After inoculating and inoculating the inoculation hole of the raw wood, the raw wood is cultivated by burying it in a buried bed for culture using Asama sand, and the ash is mainly composed of calcium and phosphorus germanium, selenium, and A skin cleanser characterized by blending, as a detergent component, a charcoal of ganoderma, which is obtained by heating silicon-containing ganoderma for a long period of time and carbonizing in almost anoxic condition. After inoculating and inoculating the inoculation hole of the raw wood, the raw wood is cultivated by burying it in a buried bed for culture using Asama sand, and the ash is mainly composed of calcium and phosphorus germanium, selenium, and A cosmetic agent characterized by blending, in a cosmetic ingredient, a charcoal of a ganoderma, which is obtained by heating a silicon-containing ganoderma over a long period of time and carbonizing in a substantially oxygen-free state. After inoculating and inoculating the inoculation hole of the raw wood, the raw wood is cultivated by burying it in a buried bed for culture using Asama sand, and the ash is mainly composed of calcium and phosphorus germanium, selenium, and A dentifrice characterized by blending, in a dentifrice component, a charcoal of ganoderma, which is obtained by heating silicon-containing ganoderma for a long period of time and carbonizing it in an almost oxygen-free state.

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