JP3482854B2 - Blister tray film and blister tray and blister pack - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical instrument such as a syringe, a film for a tray in a blister pack consisting of a tray and a lid, a tray and a blister pack, and more particularly, to tearing and cutting the blister pack when opening. It is the one.

[0002]

2. Description of the Related Art In a tray used for a blister pack or the like, a film is formed by vacuum and / or pressure forming. This film is limited to an unstretched film in terms of molding. Generally, an unstretched film has characteristics of high extensibility and poor tearability. That is, when tearing, the film stretches and does not cut. For this reason, the opening of these containers has been performed by peeling off the portion bonded to the lid member. Further, since the lid member is a film, it is easy to provide tearability in a predetermined direction.

[0003]

Since the opening by peeling must be performed individually for each container,
There was a problem that it could not be dealt with in the usage situation where a large number of containers had to be opened each time. In addition, since the wall surface of the tray remains after the opening by peeling, the operation of overcoming the wall surface and taking out the content is necessary when the content is taken out. In order to make this operation unnecessary, there is no means other than completely removing the lid material and opening the tray entirely, but this operation itself is also complicated because it has to be peeled over a long distance. .

Therefore, by simply tearing the tray and the lid material at the same time in a state where the blister pack in the state of storing the contents is traversed by the storing portion, and opening the side portions of the blister pack at the entire surface, the blister pack is tilted. A blister pack that can easily take out the contents has been desired.

As a solution, it is known that the structure of the film used for the tray of the blister pack is improved to impart a tear property. Specifically, the film constitution is a three-layer constitution of surface layer / base material layer / sealant layer, and an ionomer is adopted as the base material layer. This is a structure in which the surface layer and the sealant layer are also cut in conjunction with the tearing of the ionomer by utilizing the property that the ionomer itself has tearing properties even in a non-stretched state.

However, in the multilayer film having the above-mentioned constitution, the known ones are limited to those which are laminated by co-extrusion as the laminating method. When a laminated film is manufactured by co-pressing, a large number of products having the same structure (material, film thickness, etc.) must be manufactured due to problems in the manufacturing process. Therefore, there is a problem in that it is not possible to meet the demand for products having different required configurations (materials, film thicknesses, etc.), or for providing an additional function by adding other layers to the basic three-layer configuration.

Therefore, according to the present invention, various kinds of polyolefin resins are laminated on the front and back surfaces of an ionomer as a base material by known lamination such as dry, wet, and extrusion, depending on the application, to obtain a required constitution (material, It can be applied to products with different film thickness. In addition, a blister tray film excellent in tearability, and a blister tray and a blister that can easily meet the demand for adding an additional function to the basic three-layer structure by adding another layer are presented.

[0008]

According to claim 1 of the present invention
The invention is a film for blister tray, which is obtained by laminating unstretched polyolefin on both front and back surfaces of an ionomer by lamination.

The invention according to claim 2 of the present invention is the above contract.
In the film for blister trays according to claim 1 ,
The ionomer and at least one of the front and back unstretched poly
An adhesive layer is provided between the olefin and the olefin.
It is a film for restart trays.

The invention according to claim 3 of the present invention is the above contract.
The film for blister trays according to claim 1 or 2
And the total thickness of the blister tray film is 50
~ 300 μm, and the thickness of the ionomer is
Thickness ratio of film for blister tray to total thickness
The blister is characterized by 10-80%
This is a laye film.

The invention according to claim 4 of the present invention is the above contract.
The blister tray according to any one of claims 1 to 3.
Using a film for vacuum,
It is characterized in that an edge flange portion and an internal concave portion are formed.
It is a blister tray.

The invention according to claim 5 of the present invention is the above contract.
In the flange portion of the blister tray according to claim 4,
It is a blister pack characterized by a bonded lid.
It

[0013]

The tray and lid of the blister pack can be easily torn linearly in the direction of the short side by holding the vicinity of the notch 11 for opening provided on the peripheral portion of the blister pack by hand and pulling it. The side part can be opened separately. In this state, the contents can be taken out simply by tilting the blister pack.

[0014]

BEST MODE FOR CARRYING OUT THE INVENTION A base material layer 1 is an ionomer, an unstretched low density polyethylene is used as a surface layer 2 on the outer surface of the base material layer 1, and a low density polyethylene is used as an inner surface sealant layer 3 of the base material layer 1. A three-layer film for blister tray was laminated by extrusion lamination. This film is vacuum- and / or pressure-formed to obtain a blister tray 7 having a recess 5 inside and a flange 6 at the periphery. A lid member 1 in which the contents are put in this blister tray, and then polyethylene is laminated as a sealant layer on the inner surface of polyester as a base material layer.
0 was heat-sealed to obtain a blister pack. Then, the notch 11 for opening is provided at one location (or at a plurality of locations separated by a predetermined distance) on the longitudinal side edge of the flange of the tray 7 and the lid material 10 of the blister pack.

The film for blister tray can be laminated in three layers at the same time, or can be laminated in two steps. For example, it is a step of laminating the surface layer 2 and the base material layer 1 and then laminating the sealant layer 3 on the base material layer 1 of the two-layer film.

In the present invention, it is effective to increase the lamination strength between the layers of the blister tray film. This is because the tear property of the ionomer is linked to the surface layer and the sealant layer to improve the tear property of the film as a whole. If the lamination strength is low, if peeling occurs between the layers during the blister tray tearing operation, the tearability of the ionomer will not work with the surface layer and sealant layer, and the surface layer,
This is because the non-tearability of the sealant layer causes a phenomenon in which the tearing of the entire blister tray stops.

As a means for further improving the lamination strength between layers of the film for blister tray,
An adhesive layer may be provided between the layers. For example, between the base material layer and the sealant layer, a urethane-based anchor coat material can be provided as an adhesive layer on the base material layer subjected to corona treatment.

Notch 11 for opening this blister pack
By holding and pulling the vicinity by hand, the tray and the lid of the blister pack can be easily torn linearly in the short side direction, and the one side portion of the blister pack can be separated and opened. In this state, the contents can be taken out simply by tilting the blister pack.

The present invention has a basic structure of a three-layer film in which a polyolefin resin is laminated on both sides of an ionomer by lamination, but it is possible to add a function by laminating another film on this film by lamination. As an example, in order to enhance the puncture strength (falling strength) due to the content of the present invention, by laminating a linear low-density polyethylene having excellent puncture property on the sealant layer and / or the outer surface by lamination, it is easy. Can handle.

The total thickness of the laminated film of the present invention is
50-300 considering the molding suitability of the blister pack
It is preferably set to μm. And in order to improve the tearability in the present invention, the thickness of the ionomer,
The thickness ratio to the total thickness of the laminated film is preferably set within the range of 10 to 80%.

The lid material used in the present invention may be of any type as long as it has tearability. However, in addition to tearing which is the original opening means of the present invention, peeling means is also provided, so that the sealant is used. A layer having peelability (interlayer, aggregation, etc.) can also be used.

[0022]

INDUSTRIAL APPLICABILITY The present invention has a required constitution (material, material) by laminating various kinds of polyolefin resins on the front and back surfaces of an ionomer as a base material by known lamination such as dry, wet and extrusion depending on the application. It can be applied to products with different film thickness. Further, it is a film for blistering tray excellent in tearability capable of easily meeting the demand for adding an additional function to the basic three-layer structure, and a blistering tray and a blister.

[0023]

Example 1 A three-layer film for blister packs having a total thickness of 200 μm, which was made of the following materials and thicknesses, was first laminated with a surface layer and a base material layer by extrusion, and then a corona was formed on the inner surface of the base material layer. After the treatment, a sealant layer is laminated by extrusion lamination via a urethane anchor coating agent to manufacture. Surface layer: low density polyethylene (55 μm) Substrate layer: ionomer (90 μm) * Thickness ratio to total thickness = 45% Sealant layer: low density polyethylene (55 μm)

Example 2 A three-layer blister pack film having a total thickness of 200 μm, which was made of the following materials and thicknesses, was first laminated with a surface layer and a base material layer by extrusion, and then a sealant layer was formed on the inner surface of the base material layer. Are laminated by extrusion lamination. Surface layer: low density polyethylene (5
5 μm) Base material layer: Ionomer (90 μm) * Thickness ratio to total thickness = 45% Sealant layer: Low density polyethylene (55 μm)

Comparative Example 1 A three-layer film for blister pack having a total thickness of 200 μm, which is made of the following materials and thicknesses, is manufactured by laminating each layer by co-expansion and inflation. Surface layer: ethylene-vinyl acetate copolymer (66 μm) Substrate layer: ionomer (68 μm) * Thickness ratio to total thickness = 34% Sealant layer: ethylene-vinyl acetate copolymer (66 μm)
m)

Comparative Example 2 A three-layer film for blister pack having a total thickness of 200 μm, which is made of the following materials and thicknesses, is laminated by co-expansion and inflation. Surface layer: ethylene-vinyl acetate copolymer (40 μm) Substrate layer: ionomer (120 μm) * thickness ratio to total thickness = 60% Sealant layer: ethylene-vinyl acetate copolymer (40 μm)
m)

In order to judge the tearability of Examples 1 and 2, Comparative Examples 1 and 2, tensile rupture strength, elongation, tear strength (method C (right angle tearing method), and molded product (blister pack tray) ) Of the tear strength was measured. The results are shown in Table 1. (1) Tensile breaking strength JIS K7127 conformity ・ Test piece width: 15 mm ・ Tensile speed: 200 mm / min (2) Elongation JIS K7127 conformity ・ Test piece width: 15 mm ・ Tensile speed: 200 mm / min (3) Tear strength (3- 1) JIS K7128 compliant (method C, right-angled tearing method) ・ Pulling speed: 200 mm / min (3-2) Tear strength of molded product (blister pack tray) The test piece of this test is as shown in FIG. A flange portion in the longitudinal direction of a blister pack tray formed by vacuum and / or pressure forming the films of Examples 1 and 2 and Comparative Examples 1 and 2 is cut into strips to form a test piece 20. Then, a test piece cut into a strip shape is provided with a cut having a predetermined length at the center of one side in the short side direction, and the two sides divided by this cut are sandwiched by a tensile tester, respectively, and a tensile tester is used. Then, each side of this test piece was pulled up and down, and the load when the base of the cut was torn was measured.

[0028]

[Table 1] * TD: Elmendorf tear strength in almost right angle direction MD: Elmendorf tear strength in machine direction

As shown in Table 1, it was found that Examples 1 and 2 were torn at a smaller load than Comparative Examples 1 and 2. Therefore, Examples 1 and 2 are Comparative Examples 1 and 2.
It will have better tearability. In addition, in comparison between Example 1 and Example 2, it was found that tearing occurred in Example 1 with a smaller load than in Example 2. This is presumed to be because the adhesive layer between the layers was increased in Example 1 so that the adhesive strength between the layers was increased and the tearability of the ionomer strengthened the interlocking with the tearability of the surface layer.

Example 3 A four-layer blister pack film having a total thickness of 180 μm, which was composed of the following materials and layer thicknesses, was first laminated with a surface layer and a base material layer by extrusion, and a sealant layer was formed via an adhesive layer. It is manufactured by laminating by extrusion lamination. With this structure, the linear low density polyethylene of the sealant layer has high puncture strength. Surface layer: unstretched low-density polyethylene (30 μm) Substrate layer: Ionomer (90 μm) * Thickness ratio to total thickness = 50% Adhesive layer: Polyethylene (30 μm) Sealant layer: Linear low-density polyethylene (30 μm)

[Brief description of drawings]

FIG. 1 is a perspective view of a blister pack of the present invention in a cut state.

FIG. 2 is an explanatory diagram showing a measuring method for measuring the tear strength of a molded product according to the present invention.

[Explanation of symbols]

1 ... Base material layer 2 ... Surface layer 3 ... Sealant layer 5 ... Recess 6 ... Flange 7 ... Blister tray 10 ... Lid 11 ... Notch

─────────────────────────────────────────────────── ─── Continuation of the front page (72) Inventor Shinsei Yamazaki 1-5-1, Taito, Taito-ku, Tokyo Toppan Printing Co., Ltd. (56) References JP-A-3-38342 (JP, A) JP-A 11-91044 (JP, A) JP-A-9-1744 (JP, A) JP-A-2-204034 (JP, A) Actually opened 54-92882 (JP, U) Actually opened 59-176526 (JP, U) Actual development Sho 62-31057 (JP, U) Special table 2001-524038 (JP, A) (58) Fields investigated (Int.Cl. ⁷ , DB name) B32B 1/00-35/00

Claims (5)

(57) [Claims] 1. A film for blister tray, which comprises laminating unstretched polyolefin on both front and back surfaces of an ionomer by lamination. 2. The ionomer and at least one of the front and back
That an adhesive layer was provided between the unstretched polyolefin and
The blister tray fill according to claim 1, characterized in that
Mu. 3. The total thickness of the blister tray film
Is 50 to 300 μm, and the thickness of the ionomer is
The total thickness of the blister tray film
The thickness ratio is 10 to 80%.
The film for blister trays according to 1 or 2. 4. A boot according to any one of claims 1 to 3.
Vacuum or / and compressed air using restart tray film
Forming the peripheral flange and internal recess by molding
Blister tray characterized by that. 5. The blister tray according to claim 4,
Blister with a lid bonded to the flange
-Pack.