JP3455481B2 - Dietary supplement containing brown sugar extract - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION The present invention is blended with brown sugar extract
And relates to a dietary supplement comprising, its object is the antioxidant effect and a body fat reducing action has the effect of improving obesity and proportions, also there be skin, have a cosmetic effect of improving such skin dullness Moreover, since it has an antioxidant action, it is intended to provide a dietary supplement that is highly safe for the human body, when it is mixed with food, it prevents the oxidation of the food itself and does not require the addition of a synthetic antioxidant. In addition, in the present invention
By the way, brown sugar extract is obtained by removing sugar from brown sugar.
From the resulting black pigment component fraction, methoxyphenylglucose
Obtained by removing saccharide compounds
It

[0002]

2. Description of the Related Art In recent years, obesity due to diversification of diet and lack of exercise tends to increase. Obesity is closely related to daily life, and elimination of obesity requires constant improvement of life. However, improvement of daily lifestyle is not easy, and it is difficult to continue for a long time.

On the other hand, it has been reported that the components contained in the black pigment component fraction of brown sugar have excellent anti-allergic action, anti-arteriosclerosis-like action, and glucose absorption-suppressing action. No. -203452 discloses that methoxyphenylglucose compounds contained in the black pigment component fraction have excellent antiallergic action and glucose absorption inhibitory action.

[0004]

DISCLOSURE OF THE INVENTION The inventors of the present invention continued their diligent research on the pigment component of brown sugar, and found that it was obtained by removing methoxyphenylglucose compounds from the fraction of brown pigment derived from brown sugar. Brown sugar extract has an excellent antioxidant effect, and is effective in reducing body fat of a person who eats the food because it suppresses the production of lipid peroxide in the compounded food, and the brown sugar extract itself is also effective. It has been found that it has an excellent body fat reducing action, a cosmetic effect such as improvement of skin roughness and dullness of the skin, and is extremely safe, and the present invention has been completed.

[0005]

That is, the invention according to claim 1 relates to a dietary supplement characterized in that it contains 0.10 to 10.00% by weight of brown sugar extract. The invention according to claim 1 relates to the dietary supplement according to claim 1, characterized in that the brown sugar extract is a Maillard reaction product, and the invention according to claim 3, wherein at least melanoidin is present as the Maillard reaction product. The dietary supplement according to claim 2, wherein the dietary supplement is contained.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION The dietary supplement according to the present invention contains brown sugar extract as an active ingredient. This brown sugar extract can be obtained by removing methoxyphenylglucose compounds from a black pigment component fraction obtained by removing sugar from brown sugar, and specifically, Maillard reaction product, caramelization reaction. It consists of products.

[0007] The Maillard reaction is a browning phenomenon that occurs when a mixed aqueous solution of an amino acid and a reducing sugar is heated, and is a hydroxyl group capable of forming a glycoside with an amino group of an amino compound such as an amino acid or protein and a reducing sugar. It is a reaction that occurs between and. This sugar-amino condensation reaction is used as the first-step reaction, and then a decomposition reaction is caused to occur. Various reaction products are formed, such as those bound to.

Among these Maillard reaction products, melanoidin is the final product produced in the latter stage of the reaction, which is a polymerized black substance, and its aqueous solution is acidic. It has already been reported that this melanoidin has an antioxidant property and also has an ability to eliminate active oxygen. The present inventors have found that brown sugar extract containing a large amount of melanoidin is excellent in cosmetic effect, as is clear from the test examples described later. In addition, brown sugar extract has an excellent antioxidant ability and can suppress the production of lipid peroxides in foods, so that the body fat of a person who eats the foods can be reduced. Moreover, since the brown sugar extract itself also has an excellent body fat reducing effect as described later, it can synergistically exhibit an excellent antiobesity effect when used as an antioxidant for foods.

As a method for obtaining brown sugar extract, the following methods can be exemplified. First, after dissolving brown sugar in water, an adsorbent is used to mainly adsorb the black pigment component fraction. The adsorbent is washed with water to remove sugars, and then the adsorbed dye component is eluted with a solvent to obtain a black dye component fraction. As the adsorbent used at this time, Amberlite XA
D-1, Amberlite XAD-2, Selvachrome YA
D-2 etc. can be illustrated. The amount of the adsorbent used is not particularly limited, but may be 30 to 300 times by weight, preferably 50 to 200 times by weight the amount of the dye component. The solvent used for elution is not particularly limited, but a lower alcohol solvent such as methanol or ethanol is preferably used. Finally, a brown sugar extract can be obtained by removing phenylglucose compounds from the obtained black pigment component fraction. Further, other extraction methods, for example, a method of obtaining brown sugar extract by cold-soaking or hot-soaking brown sugar in a lower alcohol such as methanol or ethanol, and then filtering and refining can be used.

In the dietary supplement according to the present invention, when the brown sugar extract which is an active ingredient is mainly used as an antioxidant, the amount of the brown sugar extract which is an active ingredient is not particularly limited, but 0.10 to 10 It is good to set it as 10.00 weight%.
This is not preferable when the amount is less than 0.10% by weight, because the sufficient effect is not exhibited, and even when the amount is more than 10.00% by weight, no further effect can be expected. Is also not preferable.

Further, in order to obtain a dietary supplement that exerts a cosmetic effect such as reduction of body fat, improvement of skin roughness and dullness of skin, the daily intake of brown sugar extract is usually 1 mg to 10 mg.
The blended food may be adjusted to be 0 mg. In addition, the form of the food is not particularly limited, and it is preferable that it is a form that can be taken as a normal food for a long period of time, and examples thereof include tablets, granules, powders, soft drinks, confectionery, and bread. You can Also, food additives, bulking agents,
Flavors, sweeteners, thickeners and the like can be appropriately mixed within a range that does not impair the effects of the present invention.

[0012]

EXAMPLES The present invention will be described in detail below based on examples. However, the present invention is not limited to the following examples. (Example 1) Polystyrene resin (cerva chrome YAD
-2) 300 g was dispersed in 1 L of water and packed in a column having an inner diameter of 8 cm. 5k brown sugar dissolved in 25L of water
g was allowed to flow down at a flow rate of 20 ml / min to mainly adsorb the pigment component of brown sugar to the resin. Next, water was made to flow down to remove sugars, and then 20% methanol was made to flow down at a flow rate of 10 ml / min to elute the black pigment component fraction. Flowing was continued until there was no color in the flowing liquid. The falling liquid was concentrated under reduced pressure to obtain 19 g of a black residue. 4 g of brown sugar extract obtained by removing methoxyphenyl glucose compounds by column chromatography was used as a sample of Example 1.

Example 2 0.9 g of melanoidin obtained by removing 2 g of brown sugar extract obtained in Example 1 by gel filtration column chromatography was used as a sample of Example 2.

(Test Example 1) Using Examples 1 and 2, Table 1
Three types of powders were prepared according to the composition shown in.

[Table 1]

Women whose body weight is within 10% around the standard value 6
We divided 0 people into two groups of 30 people each. Two powders prepared in the above two groups respectively (1 pack 2.1
g) was taken as a group to be taken, and one packet was taken each day in the morning and evening. The increase / decrease in waist and body weight after 3 months was scored at four levels shown in Table 2.

[Table 2]

Table 3 shows the results of calculating the average value of the points of 30 persons.
Shown in.

[Table 3]

As can be seen from the results in Table 3, the dietary supplement containing the brown sugar extract according to the present invention has an effect of reducing body fat and a cosmetic effect of improving protion. Also, it can be seen that the beauty effect is enhanced as the amount of melanoidin is increased.

Test Example 2 20 women were divided into two groups of 10 women each. Two groups, one with skin
The other group was a group for observing the degree of improvement of skin dullness, and the powder (1 pack 2.1 g) using the prepared sample of Example 1 was taken one each in the morning, day and night. The degree of dullness of the skin before taking, the degree of dullness of the skin and the degree of dullness of the skin and dullness of the skin 4 weeks after taking were evaluated according to the five levels shown in Table 4.

[Table 4]

The results are shown in Table 5. It should be noted that in Table 5, the marked effect means that the evaluation before and after taking was increased by 3 levels or more, and the effective value means that the evaluation was increased by 2 levels. In addition, “slightly effective” means that the evaluation increased by one level, “ineffective” means that the evaluation did not increase at all, and “improvement rate” is the ratio of excellent effect and effective effect (effective group) to the whole. is there.

[Table 5]

As can be seen from the results in Table 5, the dietary supplement containing the brown sugar extract according to the present invention has a cosmetic effect of improving skin roughness and dullness of the skin. After the test,
No abnormality was observed on the skin of the subject.

(Test Example 3) Using the samples of Examples 1 and 2, the antioxidant capacity was measured according to the following method. First,
1 g of linoleic acid dissolved in 8% by weight of ethanol 1
Weight percent of each sample was added. This test solution was placed in a constant temperature bath at 60 ° C. and continuously aerated for 3 hours using an air pump. Then, chloroform was used to extract linoleic acid, and its POV (peroxide value) was measured. In addition, the same measurement was performed using a solution to which each sample solution was not added as a control solution. The results are shown in Table 6.

[0022]

[Table 6]

As can be seen from the results in Table 6, the dietary supplement containing the brown sugar extract according to the present invention has an excellent antioxidant effect.

The following is an example of a dietary supplement containing the brown sugar extract according to the present invention. (Formulation example 1)

[Table 7]

(Formulation Example 2)

[Table 8]

(Formulation Example 3)

[Table 9]

[0027]

As described in detail above, the invention according to claim 1 relates to a dietary supplement characterized in that it contains 0.10 to 10.00% by weight of brown sugar extract. The invention according to claim 1 relates to the dietary supplement according to claim 1, characterized in that the brown sugar extract is a Maillard reaction product, and the invention according to claim 3, wherein at least melanoidin is present as the Maillard reaction product. Since it relates to the dietary supplement according to claim 2, characterized in that it is contained, it is possible to suppress the production of lipid peroxide in the food because it has an excellent antioxidant action,
Therefore, the body fat reducing effect can be exerted. Moreover, since brown sugar extract itself also has a body fat reducing effect, it can be a dietary supplement having an excellent antiobesity effect. In addition, it is possible to provide a highly safe nutritional supplement having a cosmetic effect of improving rough skin and dull skin.

Claims (3)

(57) [Claims] 1. A dietary supplement comprising 0.10 to 10.00% by weight of brown sugar extract. 2. The dietary supplement according to claim 1, wherein the brown sugar extract is a Maillard reaction product. 3. The dietary supplement according to claim 2, wherein at least melanoidin is contained as the Maillard reaction product.