JP3403258B2 - Fluid flow path cleaning method and cleaning device - Google Patents

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cleaning method and a cleaning apparatus for various fluid channels such as a dialysate channel of an artificial dialyzer and a fluid channel of a food plant.

[0002]

2. Description of the Related Art Artificial dialysis is a method of treatment for patients with chronic renal failure having impaired functions of removing waste products and water from the blood of the kidney, and adjusting the concentrations of components such as sodium, potassium and calcium in appropriate amounts. The dialysate and the blood extracted from the vein of the dialysis patient are exposed through the dialysis membrane, and sodium, potassium, calcium, urea, water, etc. are exchanged between the dialysate and the blood by the diffusion principle. As a result, excess metabolites and water are removed from the blood, and the purified blood is returned to the dialysis patient to eliminate the uremic symptoms. In such an artificial dialysis apparatus for performing artificial dialysis, protein components, gram-negative bacteria, and toxins dialyzed from the patient's blood in pipes and hoses (dialysis fluid flow paths of patient monitoring devices, especially downstream flow paths of dialyzer). Etc. will adhere and it will easily become a hotbed for bacteria. Therefore, it is necessary to wash these regularly, and conventionally, washing using pure water and a chemical solution having reverse osmosis is performed. For example, when dialysis of one patient is completed, the reverse osmosis water is circulated in the dialysis machine for about 30 minutes each time to wash the dialysate flow path. In addition to this washing, after each day of dialysis treatment, reverse osmosis water is circulated in the dialysis machine for about 30 minutes to wash the dialysate flow path, and then for about 30 minutes to remove citric acid crystals. A 1% solution of reverse osmosis water is passed through the dialysate flow path for sterilization and washing. Further, reverse osmosis water is allowed to flow for about 30 minutes to wash the dialysate flow path with an acid, and then chlorine dioxide (Cl 2
A solution in which O ₂ ) is dissolved in reverse osmosis water is passed through the dialysate flow path for sterilization and washing. Then, this chlorine dioxide aqueous solution is allowed to stay in the dialysate flow path and left to stand for 4 to 5 hours, and finally about 2
Time reverse osmosis water is flown to wash away the hypochlorous acid component from the dialysate flow path. Then, the residual chlorine concentration after washing is measured, and after confirming that sufficient washing is performed until the residual chlorine concentration becomes smaller than a specified value, preparations for flowing the next dialysate are made. Furthermore, once a week, instead of the sterilization and washing with the 1% citric acid solution and the chlorine dioxide solution described above, the dialysate channel is washed with a chemical solution that decomposes and removes the protein adhering to the dialysate channel. , Make sterilization cleaning more reliable.

On the other hand, in plants that handle fluid foods, such as dairy plants, fruit juice beverage plants, and brewing plants, or pharmaceutical plants, in order to keep the tanks and pipelines for fluid foods clean and hygienic, Washed, sterilized or sterilized. Conventionally, this kind of sterilization cleaning treatment has been performed using nitric acid, caustic soda, and warm water. That is, nitric acid, caustic soda, and warm water are stored in each of the three tanks, and after first cleaning the flow path with warm water, acid cleaning using nitric acid is performed.
Subsequently, hot water was poured to wash away nitric acid, and then alkaline washing with caustic soda was performed. By the acid cleaning and the alkali cleaning, waste products such as fluid foods adhering to the inside of the tank or the pipeline are removed, and finally hot water of high temperature is introduced into the flow path for sterilization.

[0004]

However, even if the dialysate flow passage is sterilized and washed by the conventional washing method described above, there are places where sterilization and washing are difficult due to the structure of the dialyzer, and such a region is a hot bed of bacteria. Experience has shown that it is easy to become. For example, a pair of stock solution tanks are connected to the automatic dialysate supply device, and one tank (hereinafter referred to as tank A) has a dialysate stock solution in which substances such as calcium, magnesium, potassium and sodium are prepared in appropriate amounts. Is stored, and baking soda is stored in the other tank (hereinafter referred to as tank B). Of these, since a high-concentration dialysate flows through the path connecting the tank A and the dialysate automatic supply device, the flow path is not contaminated by bacteria due to the sterilizing action of the dialysate. However, in the route connecting the tank B and the automatic dialysate supply device, baking soda, which does not have a sufficient sterilizing ability, is circulated, so that it easily becomes a hotbed of bacteria. In order to sterilize this route, a diluted solution of hypochlorous acid or the like may be stored in the tank B, and this hypochlorous acid solution may be passed through the dialysate flow path through the same route as during dialysis. However,
Since the tank B is a tank for storing dialysate, if a drug such as a hypochlorous acid solution is stored therein, it is necessary to sufficiently wash the tank B until the drug component is exhausted.
This washing requires a large amount of reverse osmosis water and washing time. For this reason, the route connecting the tank B and the dialysate automatic feeder is likely to become a hotbed of bacteria.
In addition, when viewed comprehensively, the amount of pure water required for cleaning is enormous, and the cleaning time is long. In fact, the cleaning time of the dialysis machine was about 50% of the dialysis time, and 0.15 t / day of pure water was used for one dialysis machine. Therefore, in order to perform dialysis treatment for a large number of patients, it is necessary to introduce a large number of dialysis machines or a pure water production system with a large production capacity, and to realize timely and inexpensive medical care. It was a neck. It has also been found that toxins such as endotoxin and bacteria such as Gram-negative bacteria are hidden and attached to protein components and the like on the hose and the like of the dialysis machine. Therefore, if you do not pour the disinfectant or sterilizing solution after sufficiently removing the protein component,
It cannot remove endotoxin or kill Gram-negative bacteria. Therefore, after washing with sufficient reverse osmosis water to remove protein components, toxins are removed and bacteria are sterilized using expensive chemicals containing chlorine, hypochlorite, EDTA, etc. It was necessary to wash with reverse osmosis water.

On the other hand, when nitric acid or caustic soda is used as a cleaning liquid for acid cleaning and alkali cleaning in the cleaning of the flow path of a food plant, it is necessary to treat these waste liquids after cleaning. Therefore, it is necessary to separately provide a waste liquid treatment device for the cleaning liquid, which not only increases the size of the device but is also disadvantageous in terms of cost. Further, in the method of performing sterilization and sterilization treatment with high-temperature hot water after acid cleaning and alkali cleaning, it is necessary to control the hot water to a temperature at which the sterilization / sterilization effect can be sufficiently exerted, and if the hot water does not rise to the required temperature, Even if the water is flown, it is not possible to sufficiently sterilize the bacteria that have propagated at the location of the waste products attached to the tank or the flow path.
Further, for sterilization and sterilization by heat, a separate hot water supply device is required, and as described above, it is also necessary to provide a controller that appropriately controls the temperature of the hot water.

The present invention has been made in view of the above-mentioned problems of the prior art, and can be used for a short time without performing waste liquid treatment on a dialysate flow path of an artificial dialyzer or a fluid flow path of a food plant. In addition, the purpose is to sterilize and wash at low cost.

[0007]

In order to achieve the above object, according to the present invention, water selected from the group consisting of tap water, reverse osmosis water, pure water and soft water treated tap water is electrolyzed. Provided is a method for cleaning a fluid flow path, which uses the obtained electrolyzed water to clean the fluid flow path. By electrolyzing water selected from the group consisting of tap water, reverse osmosis water, pure water and tap water treated with soft water, alkaline electrolyzed water and acid electrolyzed water are obtained. But you can use it. However, it is more preferable to wash the flow path of the fluid by alternately using the alkaline electrolyzed water and the acidic electrolyzed water. At this time, the order of using the alkaline electrolyzed water and the acidic electrolyzed water is not particularly limited, at least, after washing the flow path of the fluid using alkaline electrolyzed water, then washing the flow path of the fluid using acidic electrolyzed water Is more preferably performed. Further, more preferably, after washing the flow passage of the fluid with the alkaline electrolyzed water, the flow passage of the fluid is washed with the acidic electrolyzed water, then the fluid of the fluid with water selected from the group Clean the flow path. The water to be electrolyzed is selected from the group consisting of tap water, reverse osmosis water, pure water and tap water treated with soft water, but dissociation degree such as sodium chloride, potassium chloride, calcium chloride is large in order to enhance electrolysis efficiency. A substance may be added to the water.

In order to achieve the above object, according to the present invention, an anode chamber and a cathode chamber are formed inside by a diaphragm, and an electrode plate is provided in each of the anode chamber and the cathode chamber. An electrolyzer that produces acidic electrolyzed water in the anode chamber and alkaline electrolyzed water in the cathode chamber,
A conduit for guiding the acidic electrolyzed water to the target fluid flow path, a conduit for guiding the alkaline electrolyzed water to the target fluid flow path, and at least the acidic electrolyzed water and the alkaline electrolyzed water Transfer means for transferring to the flow path of the target fluid, at least a conduit to which the acidic electrolyzed water is introduced and a conduit to which the alkaline electrolyzed water is introduced,
A valve for selectively communicating the flow path of the target fluid, a sensor for detecting at least the pH value of the acidic electrolyzed water or the oxidation-reduction potential of the acidic electrolyzed water, and detection by the sensor The determined pH value or redox potential is for judging whether or not it is within a reference range input in advance, and for stopping the supply of electrolyzed water to the flow path of the fluid when it is outside the reference range. There is provided a cleaning device for a fluid flow path including a control means. At this time, a plurality of diaphragms may be provided in the electrolytic cell to form a plurality of anode chambers and cathode chambers. Further, the electrolytic cell according to the present invention may be a so-called continuous water flow type electrolytic cell in which electrolytic water is continuously generated and discharged while supplying electrolytic water to the electrolytic cell, or the electrolytic cell is exposed to the electrolytic cell. It may be a so-called batch type electrolytic cell in which electrolyzed water is stored and electrolyzed, and then the produced electrolyzed water is collectively discharged. Various fluid pumps such as a pressure pump and a suction pump can be used as the transfer means for transferring at least the acidic electrolyzed water and the alkaline electrolyzed water to the target fluid passage. Further, other than the fluid pump, the height difference (potential energy) may be used to cause the electrolyzed water to naturally drop into the target fluid passage. As a sensor for detecting at least the pH value of the acidic electrolyzed water or the redox potential of the acidic electrolyzed water, a sensor that can finally determine the pH value of the acidic electrolyzed water or the redox potential of the acidic electrolyzed water Good. For example, a pH sensor that measures the pH value of acidic electrolyzed water or an ORP sensor that measures the oxidation-reduction potential of acidic electrolyzed water can be exemplified. In this case, measure the pH value of alkaline electrolyzed water with a pH sensor,
It is also possible to control the pH value corresponding to this as the pH value of the acidic electrolyzed water. Similarly, the redox potential of alkaline electrolyzed water may be measured, and the redox potential corresponding thereto may be simulated as the redox potential of acidic electrolyzed water.

Further, in order to achieve the above object, according to the present invention, an anode chamber and a cathode chamber are formed inside by a diaphragm, and an electrode plate is provided in each of the anode chamber and the cathode chamber, An electrolyzer that produces acidic electrolyzed water in the anode chamber and alkaline electrolyzed water in the cathode chamber,
A polarity reversing circuit for reversing the polarity applied to the electrode plate, a first tank for storing the used amount of the acidic electrolyzed water, and a second tank for storing the used amount of the alkaline electrolyzed water. A tank, a conduit for guiding the acidic electrolyzed water stored in the first tank to a flow path of the target fluid, and a flow of the target fluid of the alkaline electrolyzed water stored in the second tank. A conduit for leading to the road,
Transfer means for transferring at least the acidic electrolyzed water and the alkaline electrolyzed water to the flow path of the target fluid,
At least the conduit through which the acidic electrolyzed water is guided and the conduit through which the alkaline electrolyzed water is guided, and either the flow path or the drainage channel of the target fluid, and a valve for selectively connecting them. A sterilizing and cleaning device for a fluid channel is provided. At this time, a plurality of diaphragms may be provided in the electrolytic cell to form a plurality of anode chambers and cathode chambers. Further, the electrolytic cell according to the present invention may be a so-called continuous water flow type electrolytic cell in which electrolytic water is continuously generated and discharged while supplying electrolytic water to the electrolytic cell, or the electrolytic cell is exposed to the electrolytic cell. It may be a so-called batch type electrolytic cell in which electrolyzed water is stored and electrolyzed, and then the produced electrolyzed water is collectively discharged. Various fluid pumps such as a pressure pump and a suction pump can be used as the transfer means for transferring at least the acidic electrolyzed water and the alkaline electrolyzed water to the target fluid passage. Further, other than the fluid pump, the height difference (potential energy) may be used to cause the electrolyzed water to naturally drop into the target fluid passage.

[0010]

In the method for cleaning a fluid passage according to the present invention, electrolytic water obtained at low cost by simply electrolyzing water selected from the group consisting of tap water, reverse osmosis water, pure water and soft water treated tap water, That is, alkaline electrolyzed water and acidic electrolyzed water are used to alternately wash the fluid flow path. In other words, alkaline electrolyzed water is used to remove the substance of the protein component adhering to a pipe or the like, and then acid electrolyzed water is used to remove toxins and kill bacteria. The alkaline electrolyzed water has an extremely large effect of eluting the substance of the protein component adhering to the dialysate flow path of the artificial dialyzer or the fluid flow path of the food plant. On the other hand, the acidic electrolyzed water has a toxin-removing action and a bactericidal action. Therefore, it is possible to remove the substance of the protein component with a relatively small amount of alkaline electrolyzed water, and moreover, the toxin such as endotoxin hidden in the substance of the protein component is removed and Gram-negative bacteria are sterilized surely with the acidic electrolyzed water. be able to. In addition,
The last cleaning performed with water selected from the group consisting of tap water, reverse osmosis water, pure water and soft water-treated tap water has the purpose of removing acidic electrolyzed water, so the amount of pure water required Is a relatively small amount. Since the electrolyzed water used in the sterilizing and cleaning method of the present invention is a non-chemical substance, it has no persistence or resistance to bacteria. Therefore, compared with the conventional sterilization cleaning using chemical substances, the cleaning time and the amount of the cleaning liquid used in the cleaning process using reverse osmosis water after the sterilization cleaning can be significantly reduced. Moreover, since it is not necessary to consider the adverse effects of the remaining chemical substances on the dialysate and foods, the cleaning liquid can be handled very easily. Further, it is not necessary to perform waste liquid treatment.

In the fluid channel cleaning device of the present invention,
A sensor for detecting at least the pH value of the acidic electrolyzed water or the oxidation-reduction potential of the acidic electrolyzed water is provided, and whether the pH value or the oxidation-reduction potential detected by this sensor is within a previously input reference range is determined. to decide. Then, when the pH value or the oxidation-reduction potential is out of the reference range, the supply of electrolyzed water to the fluid passage is stopped. As described above, the acidic electrolyzed water has a toxin-removing action and a bactericidal action of bacteria, but since these actions are known to correlate with the pH value and the redox potential, sufficient toxin When it is not possible to exert the removing effect of the above and the bactericidal effect of the bacteria, the supply of electrolyzed water is stopped to call for the necessity of the abnormal treatment.

[0012]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS An embodiment of the present invention will be described below with reference to the drawings. FIG. 1 (A) is a process diagram showing a cleaning method according to an embodiment of the present invention, which includes a cleaning process using alkaline electrolyzed water, a cleaning process using acidic electrolyzed water, and a cleaning process using pure water. It is configured. Cleaning with Alkaline Electrolyzed Water First, in the cleaning method of the present embodiment, the artificial dialysis device and the piping and hoses of a food plant that have undergone dialysis are cleaned with alkaline electrolyzed water obtained by electrolysis of water.
The alkaline electrolyzed water used at this time has a pH of 11 or more, preferably 11.3 or more. The cleaning using the alkaline electrolyzed water is a cleaning in which the alkaline electrolyzed water is left in the flow channel even if it is a circulating cleaning in which the alkaline electrolyzed water is washed while flowing in the flow channel. Alternatively, cleaning may be performed by combining these. By washing with such alkaline electrolyzed water, the substance of protein component adhering to the dialysis machine or the food plant, in particular, the pipe or the hose is removed. Moreover, since alkaline electrolyzed water has an extremely large effect of removing the substance of the protein component, the same cleaning effect can be obtained with a small amount of alkaline electrolyzed water as compared with the conventional cleaning with reverse osmosis water.

[0013] When the substance of the protein component adhering to the acidic electrolyzed water washing dialyzer and the pipes and hoses of the food plant is removed, then the electrolyzed water is used for washing to remove toxins and sterilization to kill bacteria. Perform cleaning. The pH of the acidic electrolyzed water used at this time is
Is 3 or less, preferably pH is 2.7 or less. The cleaning using the acidic electrolyzed water may be a circulating cleaning in which the acidic electrolyzed water is washed while flowing in the flow path, or a pickling cleaning in which the acidic electrolyzed water is left sealed in the flow path. Well, or a combination of these may be performed. By washing with such acidic electrolyzed water, toxins adhering to the dialysis machine, pipes and hoses of the food plant, or the main body can be removed and bacteria can be sterilized. In particular, the strongly acidic electrolyzed water having the above-mentioned pH value has an excellent toxin-removing effect and bactericidal effect, and moreover, the substance of the protein component is preferably removed by washing with the alkaline electrolyzed water in the previous step. Therefore, the removal of toxins such as endotoxin and the sterilization of Gram-negative bacteria can be performed with a small amount of acidic electrolyzed water.

Pure water cleaning When the cleaning with alkaline electrolyzed water and the cleaning with acidic electrolyzed water are completed, the substances and toxins of the protein components adhering to the fluid passages of the dialysis machine and the food plant are removed, and the bacteria are sterilized. However, pure water cleaning is performed to wash away the acidic electrolyzed water used for cleaning. This pure water cleaning needs only to remove the acidic electrolyzed water, so a small amount of cleaning in a short time is sufficient. As described above, when the cleaning method of this embodiment is used, the cleaning work which has conventionally required a long time using a large amount of pure water can be completed with a small amount of electrolyzed water and a short cleaning work. In the cleaning method shown in FIG. 1A, cleaning is performed with alkaline electrolyzed water, then with acidic electrolyzed water, and finally with pure water. In the present invention, for example, FIG.
As shown in (B), a pure water cleaning step may be provided between the alkaline electrolyzed water cleaning step and the acidic electrolyzed water cleaning step. Further, the number of times of cleaning with alkaline electrolyzed water and acidic electrolyzed water is not limited at all, and cleaning may be alternately performed a plurality of times.

Electrolyzed Water Generating Device The above-mentioned alkaline electrolyzed water and acidic electrolyzed water are, for example, shown in FIG.
It can be generated by the electrolyzed water generator shown in. FIG. 2 is a basic configuration diagram showing an electrolyzed water generator according to the cleaning method of the present invention. This electrolyzed water generator is of a so-called continuous water flow type, and has an electrolysis tank 2 that stores pure water generated by the pure water generation device 1. Inside the electrolysis tank 2, a cathode chamber 4 is formed by a diaphragm 3. And the anode chamber 5. These cathode chambers 4
Electrode plates 6 and 7 are provided in the cathode chamber 5 and the anode chamber 5, respectively.
A DC power supply 8 is connected to the electrode plate 7 provided in the so that the voltage of the anode is applied. Then, when a predetermined voltage is applied to the two electrode plates 6 and 7, the pure water continuously supplied into the electrolytic cell 2 is electrolyzed, and the cations are on the cathode side,
That is, they are collected in the cathode chamber 4. On the other hand, the anions are collected on the anode side, that is, in the anode chamber 5. At this time, since the anode chamber 5 and the cathode chamber 4 are partitioned by the diaphragm 3,
Only acidic electrolyzed water is discharged from the acidic electrolyzed water outlet 9 provided in the anode chamber 5, and only alkaline electrolyzed water is discharged from the alkaline electrolyzed water outlet 10 provided in the cathode chamber 4. . The acidic electrolyzed water collected in the anode chamber 5 is temporarily stored in the acidic electrolyzed water tank 11, and the alkaline electrolyzed water collected in the cathode chamber 4 is temporarily stored in the alkaline electrolyzed water tank 12. The pH value of the generated electrolyzed water depends on the current density in the electrolytic cell, the energization time or flow rate (contact time between electrolyzed water and the electrode plate), and the amount of electrolyte such as sodium chloride NaCl (dissociation degree). Adjusted by etc. The electrolyzed water used in the method for cleaning the fluid passage of the present invention can be produced by a device other than the above-described producing device, and is not limited to the type or producing method of the electrolyzing water producing device. Further, in order to remove the scale deposited on the cathode plate, it is preferable to perform backwashing regularly.In this case, the water immediately after the backwashing contains the removed scale, so it should be discarded. Is preferred.

The above-described method for cleaning a fluid channel according to the present invention is
For example, it is suitable for a method of sterilizing and cleaning the dialysate flow path of a dialyzer. Cleaning Device for Dialysis Machine With regard to the present invention, the cleaning system for the dialysate flow path of the dialysis device can be configured as follows. FIG. 3 is a block diagram showing an example of a cleaning system for a dialysis device including the cleaning device of the present invention, FIG. 4 is a block diagram showing another embodiment of a central supply device and a patient monitoring device, and FIG. 5 is a patient monitoring device. It is a piping flow figure which shows one Example. In this embodiment, for example, tap water is supplied to the reverse osmosis device 1 which is a pure water generator, and the pure water obtained is supplied to the first electrolyzed water generator 13 and the pure water tank 14. The switching of the pure water supply is performed by the three-way valve 15. For example, when the storage amount of the pure water tank 14 decreases, the three-way valve 15 is switched to guide the pure water generated by the pure water generator to the pure water tank side. Similarly, acidic electrolyzed water tank 1
1 and when the storage amount of the alkaline electrolyzed water tank 12 decreases, the three-way valve 15 is switched to guide the pure water generated by the pure water generator to the first electrolyzed water generator side. When supplying the pure water to the first electrolyzed water generator 13, it is preferable to add a dissociation medium such as sodium chloride or potassium chloride to the pure water and then supply it in order to enhance the electrolysis efficiency. The first electrolyzed water generator 13 has the structure described with reference to FIG. 2, and electrolyzes the supplied pure water to generate acidic electrolyzed water and alkaline electrolyzed water, and the electrolyzed acidic water tank 11 and the alkaline electrolyzed water tank, respectively. It is temporarily stored at 12. The electrolyzed water stored in the acidic electrolyzed water tank 11 and the alkaline electrolyzed water tank 12 is supplied to the second electrolyzed water generator 16, respectively. The second electrolyzed water generator 16 also has the structure shown in FIG. 2, but the acidic electrolyzed water from the acidic electrolyzed water tank 11 is supplied to the anode chamber of the second electrolyzed water generator 16 while the alkaline electrolyzed water tank 12 is supplied. The alkaline electrolyzed water from is supplied to the cathode chamber of the second electrolyzed water generator 16 and re-electrolyzed. The acidic electrolyzed water and the alkaline electrolyzed water obtained by re-electrolysis in the second electrolyzed water generator 16 are guided to the central supply device 18 by the pump 17. At this time, the outflow passage 1 of the acidic electrolyzed water from the second electrolyzed water generator 16
9 and the alkaline electrolyzed water outflow passage 20 are connected to the pure water tank 14
It is connected to a four-way valve 22 together with an outflow passage 21 of pure water from, and the fluid supplied to the central supply device 18 can be selected by appropriately switching the four-way valve 22. For example, when performing dialysis, pure water is sent from the pure water tank 14 to the central supply device 18 to generate a dialysate by the central supply device 18. On the other hand, when dialysis is finished and the dialyzer is washed, the acidic electrolyzed water, alkaline electrolyzed water and pure water are stored in the acidic electrolyzed water tank 1.
1, alkaline electrolyzed water tank 12 and pure water tank 14
To the central feeding device 18 in an appropriate order. Such switching of the four-way valve 22 is controlled by a controller of a dialysis machine (not shown). The fluid selected by the above-mentioned four-way valve 22 is fed by the pump 17 to the central supply unit 1.
8 to the patient monitoring device 23. Central feeding device 1 according to the present embodiment
8, when dialysis is performed, that is, when a dialysate is supplied to the dialyzer 24, the four-way valve 22 is switched to a position where pure water is supplied, as shown in FIG.
In a, a dialysate stock solution (stock solution in which substances such as calcium, magnesium, potassium, and sodium are prepared in appropriate amounts) stored in the tank 18A, baking soda stored in the other tank 18B, and the pure water tank 14 Is mixed with pure water to prepare a dialysate, which is sent to the patient monitor 23. In FIG. 4, “25” is a pressure reducing valve and “26” is a deaerator. Supply system from four-way valve 22 and central supply device 18
May be arranged in a one-to-one arrangement as shown in FIG. 3, but since only one type of dialysate is prepared in a single central supply, different dialysates for many patients may be used. In the case of supplying a plurality of central supplying devices, it is preferable to provide a plurality of central supplying devices in parallel as shown in FIG. In this case, the mixing ratio of pure water, dialysate stock solution and baking soda is appropriately selected in each dialysate automatic supply device 18a.

On the other hand, the patient monitoring device 23 to which the dialysate is supplied from the central supply device 18 can be constructed, for example, as shown in FIG. In the embodiment shown in the figure, the temperature and the flow rate (pressure) of the introduced dialysate are controlled, and the structure in which the bubbles contained in the dialysate are removed is adopted. Then, the dialysate controlled to a predetermined temperature and flow rate (pressure) is guided to the dialyzer 24 and dialyzed with the blood extracted from the patient. Further, as shown in FIG. 5, the dialyzer 24 is configured to be attachable / detachable to / from the supply system. When dialysis is performed on one patient, the dialyzer 24 used at that time is discarded and the dialyzer 24 is used for the next patient. New dialyzer 2
4 is attached. Further, since it is necessary to wash the dialyzer while the dialyzer 24 is removed, an adapter 27 capable of circulating the wash liquid can be attached to and detached from the mounting site of the dialyzer. Such a patient monitoring device 23 and the central supply device 18 may be connected one-to-one as shown in FIG. 3, but one patient monitoring device can dialyze only one patient. When performing dialysis on a large number of patients at the same time, it is preferable to provide a plurality of patient monitoring devices 23 in parallel with respect to one central supply device 18, as shown in FIG.

In this embodiment, the pH value and the oxidation-reduction potential (ORP) of the acidic electrolyzed water and alkaline electrolyzed water obtained in the first electrolyzed water generator 13 and the second electrolyzed water generator 16 are used.
Value) to manage the first value, for example as shown in FIG.
Sensors 28a to 28d for detecting a pH value and / or an ORP value are provided upstream and downstream of the electrolyzed water generator 13 and upstream and downstream of the second electrolyzed water generator 16.
Then, based on the sensors 28a and 28b provided upstream and downstream of the first electrolyzed water generator 13, the current density in the electrolytic cell in the first electrolyzed water generator 13, the energization time or flow rate, and the amount of addition of electrolyte such as NaCl. By controlling various electrolysis conditions such as (dissociation degree), acidic electrolyzed water and alkaline electrolyzed water having desired pH values and ORP values are produced.
1 and the alkaline electrolyzed water tank 12 respectively. The sensor 28c provided on the upstream side of the second electrolyzed water generator 16 re-measures the pH value and ORP value of the acidic electrolyzed water and alkaline electrolyzed water stored in the acidic electrolyzed water tank 11 and the alkaline electrolyzed water tank 12. If the standard value is not reached, the second electrolyzed water generator 1
The re-electrolysis is performed according to 6. And the second electrolyzed water generator 16
PH value and ORP of electrolytic water finally supplied to the central supply device 18 by a sensor 28d provided downstream of
The value is measured, and if it meets the standard value, it is supplied as it is, but if it does not meet the standard value, the supply of electrolyzed water to the central supply device 18 is stopped and a message to that effect is displayed (warning). To do.

Specifically, as shown in FIG. 3, the pH value and the ORP value detected by each of the sensors 28a to 28d are input to a controller (control means) 29 and stored in the controller 29 in advance as a reference. It is determined whether the value is within the range. If the standard value is not satisfied, a stop signal is output from the controller 29 to the pump 17 (or the four-way valve 22), and the supply of electrolytic water to the central supply device 18 is stopped. At the same time, the warning display means 3 including a display lamp and a warning buzzer
A signal is output to 0, and an abnormality of electrolyzed water is aroused. If this abnormal situation continues for a predetermined time or longer, the pump 17
Is restarted, the four-way valve 22 is switched to the pure water tank 14 side, and pure water is allowed to flow to the central supply device 18. Since the bacteria remaining in the dialysate flow path are propagated by the nutrients existing in the flow path with the passage of time, it is possible to quickly wash away the nutrients in the flow path using this pure water to remove even the slightest amount of bacteria. Control breeding. However, a warning that sterilization and cleaning has not been performed sufficiently is issued continuously, and the dialysis machine administrator is warned. in this way,
Since the pH value and the ORP value of the electrolyzed water, especially the pH value and the ORP value of the acidic electrolyzed water correlate with the sterilizing power, in order to effectively realize the bactericidal effect in the cleaning method described above, the acidic electrolysis is performed in this example. By controlling the pH value and ORP value of water and performing re-electrolysis, the reliability of sterilization power is improved. If the finally supplied acidic electrolyzed water does not reach the standard value, the planned bactericidal effect cannot be obtained sufficiently, so the supply of acidic electrolyzed water is stopped and this abnormality is called to the operator. I try to promote the maintenance of the device. In the embodiment shown in FIG. 3, four pH value and ORP value detection sensors 28a to 28d are provided upstream and downstream of the first and second electrolyzed water generators 13 and 16, respectively. The sensor 28b provided downstream of the generator 13 can be omitted. Further, in the same example, the acidic electrolyzed water has a sterilizing ability, and mainly because the sterilizing ability is to be controlled, the pH value of the acidic electrolyzed water and the OR
Although the P value is detected and the actual pH value and ORP value of the alkaline electrolyzed water are not measured by the sensor, there is no problem in providing the sensor for the alkaline electrolyzed water. However, the first and second electrolyzed water generators 13,
The acidic electrolyzed water and the alkaline electrolyzed water produced in 16 exhibit almost the same pH value and ORP value, and the function of the alkaline electrolyzed water according to the above-described cleaning method is to remove proteins and the like adhering to the flow channel. Therefore, the pH value and the ORP value of the alkaline electrolyzed water do not need to be strictly controlled. Further, in the embodiment shown in FIG. 3, two electrolyzed water generators are provided, and the first electrolyzed water generator (main) 1
When the standard value is not reached at 3, the second electrolyzed water generator (sub)
Although the re-electrolysis is performed by 16, the electrolyzed water stored in the acidic electrolyzed water tank 11 and the alkaline electrolyzed water tank 12 is recirculated to the same electrolyzed water generator to perform re-electrolysis. Good.

The embodiment described above is a specific example in which the fluid channel cleaning apparatus of the present invention is applied to the cleaning of the dialysate fluid channel of the dialysis machine. In addition to the dialysate flow path of the apparatus, it can be used as a cleaning apparatus for fluid flow paths of various plants such as a dairy product manufacturing apparatus, a liquor manufacturing apparatus, and a chemical manufacturing apparatus. As a cleaning system for these various plants, not only the cleaning system having the above-described configuration but also the system described below may be used. FIG. 6 is a configuration diagram showing a fluid channel cleaning device according to another embodiment of the present invention. A tank 1 for storing acidic electrolyzed water and alkaline electrolyzed water generated in the electrolyzed water generator 13.
Depending on the polarity of the voltage applied by the polarity reversing circuit 31, one of 1 and 12 serves as an acidic electrolyzed water tank and the other serves as an alkaline electrolyzed water tank. Hereinafter, the electrolytic water tanks 11 and 12 or the acidic electrolytic water tanks and the alkaline electrolytic water tanks 11 and 12 may be referred to for convenience. In this embodiment, for example, tap water is supplied to the reverse osmosis device 1 which is a pure water generator, and the pure water obtained is supplied to the electrolytic water generator 13 and the pure water tank 14. The switching of the pure water supply is performed by the three-way valve 15. For example, when the storage amount of the pure water tank 14 decreases, the three-way valve 15 is switched to guide the pure water generated by the pure water generator 1 to the pure water tank side. Similarly, an acidic electrolyzed water tank and an alkaline electrolyzed water tank 1
When the storage amounts of 1 and 12 decrease, the three-way valve 15 is switched to guide the pure water generated by the pure water generator 1 to the electrolyzed water generator side. When supplying pure water to the electrolyzed water generator 13, after adding a dissociation medium such as sodium chloride or potassium chloride to the pure water in order to enhance electrolysis efficiency,
It is preferable to supply. In this embodiment, a bypass 32 is provided in the flow path to the electrolyzed water generator 13, and a dissolution tank 33 for adding and dissolving sodium chloride or potassium chloride therein is provided. The electrolyzed water generator 13 has the structure described with reference to FIG. 2, and electrolyzes the supplied pure water to generate acidic electrolyzed water and alkaline electrolyzed water.
1 and 12 are temporarily stored. The electrolyzed water generator 13 of this embodiment is provided with a polarity reversing circuit 31 for reversing the polarity of the voltage applied to the anode plate and the cathode plate at a certain fixed interval. In this polarity reversing circuit 31, for example, when one electrolysis is completed, the signal of the completion is given
The polarity of the applied voltage supplied to the both electrode plates from the DC power supply in response to this signal is inverted with respect to the polarity that has been supplied until then. Some of the cations contained in the electrolyzed water are deposited as scales on the cathode plate, which reduces the electrolysis capacity. However, if the polarity of the voltage applied to the electrode plate is reversed every time one electrolysis is completed as in this example, the cathode plate on which the cations are deposited becomes the anode plate when the electrolysis is performed next, and As a result, the metal scale that has been deposited up to that point emits electrons, is cationized again, and is eluted in the electrolyzed water. Then, the eluted cations are collected in the cathode chamber, which was the anode chamber last time, and supplied as alkaline electrolyzed water. Also, it is necessary to discard the scale-containing water by ionizing the metal scale deposited on the cathode plate to remove it, and collecting the removed cations in the cathode chamber for use as alkaline electrolyzed water. Nor. However, if the polarity of the voltage applied to both electrode plates is reversed, it will be 2
Since the types of electrolyzed water discharged to the two tanks 11 and 12 are also reversed, in the present embodiment, the electrolysis in the tanks 11 and 12 is prevented so that the acid electrolyzed water and the alkaline electrolyzed water are not mixed in the tanks 11 and 12. The entire amount of water is used each time, and the remaining electrolyzed water is discarded from the drain pipes 36 and 37. Therefore, when the tank 11 is the tank for acidic electrolyzed water, the tank 12 is the tank for alkaline electrolyzed water, and when the next electrolysis is performed, the tank 11 is the tank for alkaline electrolyzed water and the tank 12 is the tank for acidic electrolyzed water. Becomes
Electrolyzed water stored in these electrolyzed water tanks 11 and 12,
And the pure water stored in the pure water tank 14 is guided to the suction pump 17 by conduits 38, 39 and 40, respectively.
From here, the fluid of interest is pumped to the flow path 41. Conduits 39, 4 connected to the two tanks 11, 12 respectively
0 is provided with three-way valves 42 and 43, and the conduit 3
9 and 40 are closed, a position where the electrolyzed water in the tanks 11 and 12 is guided to the pump 17 side, and a position where the electrolyzed water in the tanks 11 and 12 is guided to the drain pipes 36 and 37. Further, the conduit 38 connected to the pure water tank 14 is provided with an opening / closing valve 44, and switches between a position where the conduit 38 is closed and a position where the conduit 38 is communicated.

By selectively switching the three-way valves 42, 43 and the open / close valve 44, the pure water in the pure water tank 14, the acidic electrolyzed water and the alkaline electrolyzed water in the electrolyzed water tanks 11, 12 are selected. The cleaning liquid to be supplied to the target fluid channel 41 can be selected and supplied. For example, in the case of cleaning the flow path of a dairy product manufacturing plant to which protein wastes are easily attached, FIG.
It is preferable to use the cleaning method of the present invention shown in (A) or FIG. 1 (B). When the fluid flow path 41 is cleaned by the cleaning method shown in FIG.
Pure water, acidic electrolyzed water and alkaline electrolyzed water are stored in the two electrolyzed water tanks 11 and 12, respectively. Particularly, in this embodiment, the amounts of the acidic electrolyzed water and the alkaline electrolyzed water stored in the two electrolyzed water tanks 11 and 12 are set to the amounts required for one cleaning. These three tanks 1
With pure water, acidic electrolyzed water and alkaline electrolyzed water stored in 4, 11, and 12, the three-way valve 42 provided in the conduit 39 of the tank (tentatively 11) in which the alkaline electrolyzed water is stored is first operated. , The alkaline electrolyzed water is sucked by the pump 17 and pressure-fed to the flow path 41 of the target fluid. After washing with alkaline electrolyzed water for a certain period of time or until the alkaline electrolyzed water in the tank 11 is exhausted, the three-way valve 4
2 is operated to discard the alkaline electrolyzed water remaining in the tank 11 from the drain pipe 36. Next, a three-way valve 43 provided in the conduit 40 of the tank 12 in which the acidic electrolyzed water is stored
Is operated, and the acidic electrolyzed water is sucked by the pump 17 and pressure-fed to the flow path 41 of the target fluid. After washing with acidic electrolyzed water for a certain period of time or until the acid electrolyzed water in the tank 12 is exhausted, the three-way valve 43 is operated to operate the tank 12
The acidic electrolyzed water remaining in the above is discarded from the drain pipe 37.
Finally, the on-off valve 44 provided in the conduit 38 of the tank 14 in which pure water is stored is opened, the pure water is sucked by the pump 17 and pressure-fed to the flow path 41 of the target fluid, and is supplied in the previous step. Rinse the acidic electrolyzed water. Although the one-time cleaning is completed as described above, when the electrolytic electrolyzed water generator 13 next generates the electrolytic electrolyzed water and the alkaline electrolyzed water, the voltage polarity applied to the electrode plate in the previous time is reversed. And the three-way valve 15
Is switched to the electrolyzed water generator 13 side, and the pure water generated by the reverse osmosis device 1 is supplied to the electrolyzed water generator 13. Thus, by reversing the polarity of the voltage applied to the electrode plate every time one electrolysis is completed, the metal scale deposited on the cathode plate can be removed every time, and the deterioration of the electrolysis ability can be prevented. The acidic electrolyzed water generated in this way will be discharged to the tank 11 in which the alkaline electrolyzed water was stored last time, and similarly, the alkaline electrolyzed water generated by the electrolyzed water generator 13 is In the previous time, the acidic electrolyzed water is discharged to the tank 12 in which it is stored. At this time, 2
The amounts of the acidic electrolyzed water and alkaline electrolyzed water discharged to the two tanks 11 and 12 are also the amounts required for one cleaning. As described above, in the previous washing, the acidic electrolyzed water is used up in the tank 12 in which the acidic electrolyzed water is stored, and even if the acidic electrolyzed water remains, it is discarded from the drain pipe 37. The supply of alkaline electrolyzed water does not cause a problem such as a change in pH value. Such switching of the three-way valves 42, 43 and the open / close valve 44 is controlled by a controller (not shown).

In the above-mentioned embodiment, the amount of acidic electrolyzed water and the amount of alkaline electrolyzed water stored in the two electrolyzed water tanks 11 and 12 are the amounts required for one cleaning. It can be changed according to the timing of inverting the polarity applied to the. For example, when the applied polarity is reversed every n times of cleaning, the electrolytic water tank 11 is provided with an amount of acidic electrolyzed water and alkaline electrolyzed water required for n times of cleaning.
You can store them in 12 each. In this way, by reversing the polarity of the voltage applied to the electrolyzed water generator 13 every cleaning, the metal scale deposited on the cathode plate can be removed. In addition, the conduits 39 on the downstream side of the tanks 11 and 12,
As for 40, since the electrolyzed water flowing through the conduits 39, 40 is also electrolyzed water having a reverse pH value each time the polarity of the applied voltage is reversed, the problem of corrosion of the conduit through which acidic electrolyzed water flows and alkaline electrolyzed water The problem that metal scales tend to adhere to the flowing conduit is also eliminated. In addition to this, 2
The two electrolyzed water tanks 11 and 12 are not dedicated tanks for acidic electrolyzed water and alkaline electrolyzed water, respectively, and the electrolyzed water in the tank is used up before the polarity of the applied voltage is reversed. Therefore, the flow paths 34, 35 of the electrolyzed water discharged from the electrolyzed water generator 13 to the tanks 11, 12 are
Need not be switched, and the configuration of the device is greatly simplified.

It should be noted that the embodiments described above are provided for facilitating the understanding of the present invention and not for limiting the present invention. Therefore, each element disclosed in the above-described embodiments is intended to include all design changes and equivalents within the technical scope of the present invention.

[0024]

According to the present invention, electrolyzed water that can be produced at a low cost is used to sterilize and wash the fluid flow path of an artificial dialysis device or a food plant. The effect can be obtained, and the cost can be reduced. Further, the cleaning effect is larger than that of the conventional method, and the waste liquid treatment is unnecessary. As a result, the previously required washing time can be shortened, and the time spent for dialysis and the food production can be substantially lengthened. Further, the artificial dialysis device, the food plant, and the pure water generation device can be downsized, so that the spread of these devices can be expected.

[Brief description of drawings]

FIG. 1A is a process diagram showing a method for cleaning a fluid channel according to an embodiment of the present invention, and FIG. 1B is a process diagram showing a method for cleaning a fluid channel according to another embodiment of the present invention. Is.

FIG. 2 is a configuration diagram showing a specific example of an electrolyzed water generator used in the method for cleaning a fluid channel of the present invention.

FIG. 3 is a configuration diagram showing a fluid channel cleaning device according to an embodiment of the present invention.

FIG. 4 is a configuration diagram showing another embodiment of the central feeding device and the patient monitoring device according to the present invention.

FIG. 5 is a piping flow chart showing an embodiment of the patient monitoring apparatus of the present invention.

FIG. 6 is a configuration diagram showing a fluid channel cleaning device according to another embodiment of the present invention.

[Explanation of symbols]

DESCRIPTION OF SYMBOLS 1 ... Pure water generator 2 ... Electrolyte tank 3 ... Diaphragm 4 ... Cathode chamber 5 ... Anode chamber 6 ... Cathode plate 7 ... Anode plate 8 ... DC power source 9 ... Acidic electrolyzed water outlet 10 ... Alkaline electrolyzed water outlet 11 ... acidic electrolyzed water tank 12 ... alkaline electrolyzed water tank 13 ... first electrolyzed water generator 16 ... second electrolyzed water generator 18 ... central supply device 23 ... patient monitoring device
24 ... Dialyzer 28a-28d ... pH sensor 29 ... Controller (control means)

─────────────────────────────────────────────────── ─── Continuation of the front page (51) Int.Cl. ⁷ Identification code FI C11D 7/02 B08B 9/06 (72) Inventor Kazuyoshi Arai 1032-7 Kamiogino, Atsugi, Kanagawa Prefecture (72) Inventor Tatsuya Suto Shuttle Yokouchi 201 (56) 3184-4 Yokouchi, Hiratsuka City, Kanagawa Prefecture Reference (JP-A-8-11992 (JP, A) JP-A-5-309393 (JP, A) JP-A-5-68784 (JP, A) Special) Kaihei 5-68783 (JP, A) JP 7-108064 (JP, A) JP 7-171204 (JP, A) (58) Fields investigated (Int.Cl. ⁷ , DB name) B08B 9 / 027 A61M 1/14 563 B08B 3/10 C02F 1/46 C11D 7/02

Claims (5)

(57) [Claims] 1. An artificial method for sterilizing and cleaning a dialysate flow path by using electrolyzed water obtained by electrolyzing water selected from the group consisting of tap water, reverse osmosis water, pure water, and soft water-treated tap water. Transparent
A method for sterilizing and cleaning the dialysate flow path of the analyzer . 2. A dialyzing method using alkaline electrolyzed water and acidic electrolyzed water alternately obtained by electrolyzing water selected from the group consisting of tap water, reverse osmosis water, pure water, and soft water-treated tap water.
Sterilization of dialysate flow passage of artificial dialysis machine for liquid passage sterilization cleaning
Cleaning method . 3. A dialysate channel using at least alkaline electrolyzed water obtained by electrolyzing water selected from the group consisting of tap water, reverse osmosis water, pure water and soft water-treated tap water. >, And then sterilizing and washing the dialysate flow path with acidic electrolyzed water obtained by electrolyzing water selected from the group
A method for sterilizing and cleaning a dialysate flow path of an artificial dialyzer . 4. A dialysate channel is washed with alkaline electrolyzed water obtained by electrolyzing water selected from the group consisting of tap water, reverse osmosis water, pure water and soft water treated tap water, An artificial permeation for washing the dialysate flow channel with acidic electrolyzed water obtained by electrolyzing water selected from the group, and then washing the dialysate flow channel with water selected from the group.
A method for sterilizing and cleaning the dialysate flow path of the analyzer . 5. An anode chamber and a cathode chamber are formed inside by a diaphragm, and an electrode plate is provided in each of the anode chamber and the cathode chamber to generate acidic electrolyzed water in the anode chamber and the cathode chamber. An electrolytic cell for generating alkaline electrolyzed water at, a conduit for guiding the acidic electrolyzed water to the dialysate flow path of the artificial dialyzer, and a conduit for guiding the alkaline electrolyzed water to the dialysate flow path of the artificial dialyzer. A transfer means for transferring at least the acidic electrolyzed water and the alkaline electrolyzed water to the dialysate flow path of the artificial dialysis device ; at least a conduit for introducing the acidic electrolyzed water and a conduit for introducing the alkaline electrolyzed water; Artificial dialysis machine transparency
A valve for selectively communicating the deposition fluid channel , a sensor for detecting at least the pH value of the acidic electrolyzed water or the redox potential of the acidic electrolyzed water, and the pH value detected by the sensor or redox potential, as well as determining whether the reference range previously input, if it is outside the reference range permeability of the artificial dialyzer
Sterilizing and washing apparatus of the dialysate flow path of the dialysis device including a control means for stopping the supply of the electrolytic water to the 析液channel, the.