JP3351446B2 - Tapping system - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a stoppering system, and more particularly to a stoppering system suitable for fitting, for example, a rubber inner stopper to a syringe barrel as a container.

2. Description of the Related Art Conventionally, for example, Japanese Patent Publication No. 4-28386 discloses a technique for plugging an inner plug into a syringe barrel of a syringe in a vacuum state. In the technique disclosed in the above publication, first, an injection cylinder is held on one plate outside the vacuum chamber, and an inner plug is held on the other plate. And
The plate holding the plug and the plate holding the syringe are set in a vacuum chamber. Next, after the inside of the vacuum chamber is evacuated, the inner plug is pushed down by a pressing pin to temporarily tap the upper mouth of the syringe barrel. Thereafter, when the atmosphere is introduced into the vacuum chamber, a pressure difference is generated between the inside and the outside of the syringe barrel. The pressure difference causes the inner plug to be fitted deeply from the upper opening to the vicinity of the liquid surface of the drug solution. The syringe barrel thus fitted with the inner plug opens the vacuum chamber and is taken out.

As described above, in the related art, since the operation of holding the syringe barrel and the inner stopper on each plate is performed by the operator, there is a disadvantage that the operation efficiency is extremely low. Therefore, an object of the present invention is to mechanize the operation from filling of the filling liquid into the container to fitting of the inner plug into the mouth of the container under vacuum.

That is, the present invention provides a filling device for filling a filling liquid into a container having an open mouth,
A stopper device for fitting an inner plug to the mouth of the container filled by the filling device, a grouping device for grouping a predetermined number of containers having the inner stopper fitted by the stopper device, and a vacuum state in the vacuum chamber. Another object of the present invention is to provide a plugging system including a vacuum plugging device which once removes the inner plug from the mouth of the container grouped by the grouping device and fits the inner plug again into the mouth of the container.

According to such a configuration, the operations from filling of the filling liquid into the container to fitting of the inner plug to the mouth of the container under vacuum can be mechanized by the above-described devices.
Therefore, the working efficiency can be greatly improved as compared with the above-described conventional case.

BRIEF DESCRIPTION OF THE DRAWINGS FIG.
In FIG. 1, reference numeral 1 denotes a stoppering system, which is shown in FIG.
The inner stopper 3 can be fitted to the syringe 2 as a container.
ing. This stoppering system 1 includes a drug solution 4 in an injection barrel 2.
And a filling device 5 for filling the liquid
To insert the inner plug 3 into the mouth 2a of the injection cylinder 2 filled with
Plug device 6 and injection with inner plug 3 fitted by stopper device 6
Grouping device for grouping cylinders 2 by a predetermined number
And grouping by the grouping device 7
Once the inner plug 3 is removed from the mouth 2a of each syringe barrel 2,
A vacuum stopper 8 fitted to the mouth 2a under vacuum.
I have. As shown in FIG. 2, the syringe barrel 2 has an injection needle attached thereto.
With the cap 11 attached to the mounting opening 2b
The mounting opening 2b faces downward in the cup-shaped holder 12.
Inserted. Therefore, the mouth 2a of the syringe barrel 2
Is supported upward and the holder 1
The injection cylinder 2 held inside is upstream of the first conveyor 13
Supplied to Thereafter, the first conveyor 13 moves downstream.
The syringe barrel 2 in the holder 12 conveyed toward the side
A conventionally known line type disposed in the conveying process of the conveyor 13
By the filling device 5, a predetermined amount of the chemical solution 4 is sequentially contained therein.
It is designed to be filled. On the other hand, as shown in FIG.
The inner plug 3 is made of a columnar rubber,
Seals with annular projections at both axial ends and at the center
The portion 3a is formed. Also, at the center of the upper surface of the inner plug 3
Has a female screw portion 3b formed at a predetermined depth.
After the completion of the above, a pusher (not shown) is attached to the female screw portion 3b.
The tip of the key is screwed. (Popping device) The plugging device 6 is rotated clockwise to
A stopper mechanism 14 for fitting the inner plug 3 to the mouth 2a of the second port;
At the supply position A, the syringe 2 is delivered to the stoppering mechanism 14.
The supply star wheel 15 and the inner plug 3 at the discharge position B
For discharging the injection cylinder 2 fitted with from the stopper mechanism 14
At the star wheel 16 and further at the second supply position C
An inner stopper supply mechanism 17 for supplying the inner stopper 3 to the stopper mechanism 14
It consists of. Tapping mechanism 14 and both star wheels 1
5, 16 are rotated in the direction of the arrow synchronously.
The syringe 2 conveyed by the first conveyor 8 is supplied
By the feeding star wheel 15 on the first conveyor 8
After being taken out, the plugging mechanism 1 at the first supply position A
4 is supplied. On the other hand, the inner plug supply mechanism 17
A sorter 1 which forms a spiral step on the peripheral surface and is reciprocally oscillated
8 as the sorter 18 is vibrated.
Thus, a large number of the inner plugs 3 housed therein are
b are arranged in a vertical line facing upward. And in FIG.
As shown, the inner plugs 3 thus aligned in a row
Second supply position C intermediate between star wheels 12 and 13
At first, a plate-shaped gas is first
Of the stopper mechanism 14 described later.
It is designed to be supplied into each engagement recess 23b. Next
Meanwhile, as shown in FIG.
The five disks 22, 23, 24, 25 attached to the drive shaft,
26, these circles are formed when the drive shaft is driven.
The plates 22, 23, 24, 25, 26 are rotated clockwise.
It has become so. Outside the second disk 25 from below
A pocket 25 composed of an arc-shaped concave portion is provided at a circumferentially equal position.
a is formed on the outer peripheral portion of the disk 24 above it.
To the position of the pocket 25a of the disk 25,
Each pocket 24a is formed. And the above circle
As the plates 24 and 25 rotate clockwise, the injection
The holder 12 holding the tube 2 is located at the first supply position A.
Each pocket 25 is successively supplied by the supply star wheel 15.
a. Hit like this
Each holder 12 supplied to the plug mechanism 14 has its bottom face
At the same time as being supported on the lower disk 26,
It is held in the pocket 25a, and in the holder 12
The outer peripheral portion of the syringe barrel 2 is also held in the pocket 24a.
In this embodiment, each pocket 25a (24a) is held.
To prevent the holder 12 (syringe 2) from falling off by centrifugal force,
Required outside the movement trajectory of each pocket 25a (24a)
Guide members 27 and 27 'are provided over the range.
The two discs 22 and 23 located on the upper side are each
Fit the position of the syringe barrel 2 held by the socket 25a (24a).
In addition, through holes 22a and 23a are formed respectively,
The through holes 22a and 23a at these upper and lower positions are provided with stepped cylindrical
The stopper pin 28 is slidably penetrated. Tapping pin 2
8 is connected to a negative pressure source (not shown) through a movable pipe.
From the negative pressure source and into the tapping pin 28 at all times.
Pressure can be introduced. In addition, the stopper pin 28
The outer periphery of the lower part is reduced by a predetermined dimension, so
When the stopper pin 28 is lowered, the stopper pin
The lower end of the pin 28 is inserted into the female thread 3b of the inner plug 3.
The inner plug 3 can be adsorbed and held. Also a disk
23, the outer peripheral portion which is adjacent to each through hole 23a.
Moves the engaging recess 23b continuous from the through hole 23a.
Each is formed. Then, as shown in FIG.
In the example, the plate-like guide 9 is engaged with the engagement recess 23 b of the disc 23.
Is located below. Therefore, when the disc 23
In the second supply position C, the
The sheet 19 is supplied and supported on the plate-like guide 9 from the distal end portion 19a of the sheet 19.
The inserted inner plug 3 is engaged and held in each of the engagement recesses 23b, and
Are taken out one by one and immediately
So that it is sucked by the lower end of the stopper pin 28 which is lowered.
It has become. Further, on the outer peripheral portion of the stopper pin 28,
Is parallel to the axis of the stopper pin 28 and from the lower outer periphery.
The gap pins 31 are integrally attached with a slight separation.
The lower end of the gap pin 31 is closer to the lower end of the stopper pin 28.
And a predetermined dimension below. Gap pin 31
The gap pin 31 is lowered on the disk 23 located just below
When the gap pin 31 is allowed to pass
A through hole 23c for guiding the descent is provided. This uki
The lower inner peripheral portion of the through hole 23c is
Make the cross section of the inner diameter slightly larger than the outer diameter
And are formed vertically. In contrast, penetration
The upper inner peripheral portion of the hole 23c gradually increases in diameter on the upper side.
The cross section is elliptical. Thereby, the through hole 23
c, the lower end 31a of the gap pin 31 on the upper inner peripheral surface.
Is formed. And the gap pin 3
When 1 is lowered, its lower end 31a
The stopper plug is engaged with the inclined surface of the upper inner peripheral portion of the through hole 23c.
After being elastically deformed toward the through hole 28c,
It is guided by the inner circumference and penetrates vertically downward
(FIG. 4B). In this embodiment, the through hole
23c is configured in this manner, the gap pin 31
When the lower end portion 31a passes through the through hole 23c,
Not to come in contact with the inner plug 3 held in position
I have. A cam follower 32 is provided on the upper outer peripheral portion of the stopper pin 28.
The cam follower 32 is not shown.
To the ring-shaped cam member 33 attached to the fixed frame
Is engaged. Therefore, each disk 22 to 26
When rotated clockwise, each tapping pin 28 is
So that it can be moved up and down a predetermined stroke along the cam surface
It has become. In this embodiment, each of the disks 22 to 26 is
In each rotation section when rotating, each stoppering pin 28
The cam curve of the cam member 33 is adjusted so that
Is in place. That is, in the clockwise direction in FIG.
In the rotation section from a little before to the second supply position C
4A, each stopper pin 28 is kept at the raised end position shown in FIG.
Is to be carried. In this rotation section,
The lower end of the pin 28 and the lower end 31a of the gap pin 31 are both
It is hidden in the through holes 23a and 23c. Therefore, each
As the disks 22 to 26 are rotated clockwise,
And is supported on the plate-shaped guide 9 at the second supply position C.
The inner plug 3 that has been engaged is formed by each engagement recess 23 b of the disc 23.
They are sequentially taken out one by one (FIGS. 3 and 4 (a)). Next
In the position immediately after passing the second supply position C,
28 is lowered from the rising end position to a slightly lower position
And maintain its height until reaching the first supply position A.
It is. As a result, the lower end of the stopper pin 28 is
a female screw of the inner plug 3 that has penetrated through the
Inserted into the part 3b. Negative pressure is introduced into the stopper pin 28.
Since the inner plug 3 is located in the engagement recess 23b,
It is sucked and held by the stopper pin 28. In addition,
Sometimes the lower end 31a of the gap pin 31 also passes through the through hole 23c.
I do. As described above, the upper inner peripheral portion of the through hole 23c is inclined.
The inner peripheral portion below the through hole 23c is formed as a slope.
Is formed in the vertical direction, so that the lower end of the gap pin 31
31a is elastically deformed along the inclined surface,
Penetrates vertically along the inner peripheral side
You. Thereby, the gap pin 31 penetrating through the through hole 23c
The lower part is parallel to the axis of the inner plug 3 and its sealing part.
Slightly spaced from 3a. Also, in this state
The lower end 31a of the gap pin 31 is
Also protrude slightly downward. (FIG. 4 (b)). this
In the state, the engagement recess 23b holding the inner stopper 3 and the stopper
When the pin 28 moves to the first supply position A, the first supply
At position A, each pocket is
Holder 12 and holding it in the socket 24a (25a)
The supplied syringe 2 is supplied (FIGS. 4B and 2).
As a result, the syringe barrel 2 is attached to the inner stopper held by the stopper pin 28.
3 while being held at the position immediately below
The axis of the inner plug 3 held by the tapping pin 28 coincides with the axis.
Swell. Next, from the position after the first supply position A,
In the rotation section slightly before the exit position B, the stopper pin 28
Is gradually lowered to the lower end position. This allows for tapping
The inner plug 3 held by the pin 28 is moved from the inside of the engagement recess 23b.
It can be pushed down gradually toward the lower side,
At the same time, the lower end 31a of the gap pin 31 is also gradually
Descending. Thereby, it is lower than the lower surface of the inner plug 3.
The lower end 31a of the gap pin 31 located on the side
From the upper side to the tapered surface 2a 'which is the upper end of the
Together, they are elastically deformed toward the axis of the syringe barrel 2. Ma
In addition, the lower end 3 of the gap pin 31 thus elastically deformed.
1a, the bottom surface of the inner plug 3 and the lowermost seal portion 3a are upward.
(FIG. 4C). After this, add a stopper pin
The inner plug 3 and the gap pin 31 held at 28 are lowered.
As a result, the inner stopper 3 is pressed into the mouth 2 a of the syringe 2.
You. At the same time, the lowermost sealing portion of the inner plug 3
The lower portion of the gap pin 31 that has been in contact with the
Both are sandwiched between the inner peripheral surface of the mouth 2a of the injection cylinder 2.
In this state, it is inserted into the mouth 2a of the syringe barrel 2. At this time,
The outer peripheral portion of the inner plug 3 in contact with the gap pin 31 is
Is elastically deformed along the shape of the
The gap between the deformed part and the gap pin 31
become. This gap causes the inner plug 3
So that the inside of the syringe barrel 2 on the inner side communicates with the outside of the syringe barrel 2
Therefore, the inner plug 3 is pressed into the mouth 2 a of the syringe 2.
The pressure in the space inside the syringe barrel 2
Ascent can be prevented. This allows the inner stopper 3 to be
2 can be smoothly fitted to the mouth 2a. That
When the rubber inner plug 3 is pressed into the inner peripheral surface of the mouth 2a,
There is no possibility of rubber residue,
To prevent the chemical solution 4 in the syringe 2 from being contaminated by the
Wear. Thereafter, at the position immediately before the discharge position B, the tapping pin 2
8 is raised to the original rising end position, and then moved to the second supply position.
C is maintained at the rising end position. Therefore, the stopper
The lower end of the pin 28 is separated from the inner plug 3 and
Was inserted between the outer peripheral portion and the mouth 2a of the syringe barrel 2.
The lower part of the gap pin 31 is also extracted. Outer periphery of inner plug 3
Is formed with a seal portion 3a, so that the gap pin 31
When the lower part is withdrawn from between the mouth 2a and the inner plug 3,
The sealing portion 3a is in close contact with the mouth 2a of the
The inside can be completely sealed. In this way, the mouth
The injection cylinder 2 in which the inner stopper 3 is fitted to the part 2a is
Discharged from discharge position B by eel 16
It is delivered on a second conveyor 34.
And the 2nd conveyor 34 is the injection | pouring with which the inner plug 3 was fitted.
The tubes 2 are sequentially conveyed to a grouping device 7 on the downstream side. Less than
As described above, in the plugging device 6 of the present embodiment, the plugging mechanism 14
Supply of the syringe 2 and the inner stopper 3 of the
Mechanizing the fitting work
Can be improved. In the above embodiment,
A case where the invention is applied to a rotary stoppering device 1 will be described.
However, it can also be applied to line-type tapping equipment.
You. Further, the stopper pin 28 and the gap by the cam member 33 are formed.
By changing the lifting stroke of the pin 31,
Inner stopper near the liquid level of the chemical solution 4 that is on the inner side of the part 2a
3 can be plugged deeply. (Grouping device) Next, FIG. 1, FIG. 5 to FIG.
Thus, the grouping device 7 will be described. Group pin
The conveyor 7 is located at a position facing the second conveyor 34 in the conveying process.
Stopper wheel 35 provided and end of second conveyor 34
The first push-out mechanism 37 and the glue
Grouping conveyor 38 and grouping conveyor 38
Around the holder 12 grouped on 38
A second push-out mechanism 39 for pushing out to the stoppering device 8 side.
ing. Each holder conveyed by the second conveyor 34
12 (injection cylinder 2) is
Adjacent positions are abutted with each other in 12 vertical rows.
It is separated and transported downstream. First pushing mechanism 37
Follows the movement of the holder 12 conveyed by the second conveyor 34.
While moving along, at the same time on the second conveyor 34
It can move forward and backward in the direction that intersects. did
Therefore, it is gathered on the second conveyor 34 in a line of 12 pieces in a vertical line.
Holder 12 (injection
The cylinder 2) is connected to the second controller by the first pushing mechanism 37.
Twelve rods are sequentially extruded from the beer 34 in a row,
2 A pair of conveyors 34 is provided via a transfer plate 42 provided at a position adjacent to the conveyor 34.
It is to be placed on the looping conveyor 38
You. The grouping conveyor 38 includes the second conveyor 34
It is arranged in a direction orthogonal to and runs in the direction of the arrow in FIG.
The mounting surface of the grouping conveyor 38
Is the same height as the mounting surface of the second conveyor 34 and the transfer plate 42
Is set to Thereby, the first pushing mechanism 37
Therefore, the second conveyor 34 and the grouping conveyor 38
Make sure that each holder 12 does not fall when pushed up
I have to. Outside of both sides of grouping conveyor 38
A pair of guide rails 43 is provided at the position.
Second push-out mechanism 39 over looping conveyor 38
Is mounted on the guide rail 43 so as to roll freely.
I have. The second extruding mechanism 39 includes a grouping conveyor.
38, a pair of gussets disposed opposite to each other and above and near both sides of
And a grouping conveyor.
Directly above the grouping conveyor 38
A pair of flap members 45 and 46 are provided so as to cross each other.
As a result, the first pushing mechanism 37 causes the glue pin to move.
12 holders that are sequentially supplied on the conveyor 38.
Da 12 has the first and last ones
The position of the moving end is regulated by the
There is no dissipation on the looping conveyor 38. did
Accordingly, the first push-out mechanism 37 sequentially turns the glue pins.
12 holders for each vertical row supplied on the conveyor 38
Reference numeral 12 indicates that 12 holders 12 in adjacent rows contact each other.
Placed on the grouping conveyor 38
And Flap member located on the second conveyor 34 side
45 has a rectangular cross section, while a vacuum stopper is provided.
The flap member 46 on the side of the holder 8 is formed in an elongated box shape.
You. These flap members 45 and 46 are connected to the cylinder mechanism 4.
Swings up and down synchronously by 7, 47
I can do it. And these flap members 4
5 and 46 for 12 rows by the first pushing mechanism 37.
Holder 12 is extruded onto grouping conveyor 38
Until it does not interfere with the holder 12 (syringe 2)
(FIG. 6). In contrast, 12 columns
Holder 12 is extruded onto grouping conveyor 38
Then, the grouping conveyor 38 that had been stopped until then
Is driven in the direction of the arrow by a predetermined distance. As a result,
12 rows at the last position on the looping conveyor 38
Twelve eyes of holder 12 and handpiece 4 at adjacent position
2. There is a large gap between the next row of holders 12 on
I will. At this time, both flap members 45,
46 is synchronously lowered to the lower position,
The member 45 is the last 12 rows in the 12th row through the gap.
Abuts the outer peripheral portion of the holder 12 and has a flap portion.
The left end face of the material 46 has twelve holders 12 in the first row.
Abuts the outer periphery of As a result, a total of 12 columns
A total of 144 holders 12 are on the grouping conveyor 38
And the holders that are grouped
Around the two guide members 4 of the second pushing mechanism 39
4 and both flap members 45 and 46.
Thereafter, the second push-out mechanism 39 is moved to a linear drive (not shown).
To the right along the guide rail 43 depending on the structure
Since it is moved by a fixed stroke, the grouping conveyor
Total of 144 holders 1 grouped on the sleeve 38
2 is a vacuum tapping device shown by the imaginary line from the position shown by the solid line in FIG.
The position 8 is supplied to the position. At this time, vacuum stopper
A total of 144 hoses for which vacuum tapping has already been completed
If rudder 12 was present, move as described above.
The front end face of the flap member 46 has
A discharge conveyor provided from the position of the tapping device 8 to the position adjacent thereto.
４８ 上 ４８ ４８. The second pushing mechanism 39 is as described above.
When it is moved to the position of the vacuum stopper 8 as shown in FIG.
The flap members 45 and 46 do not contact the holder 12 either.
Return to the upper position. After this, immediately the second extruder
The structure 39 is returned to the position above the original grouping conveyor 38.
Return. In this way, the grouping device 7
12 vertical and horizontal rows in a row on the conveyor 38
The book holder 12 (syringe 2) was placed and the grouping was performed.
The holder 12 is supplied to a predetermined position on the side of the vacuum stopper 8.
At the same time, the vacuum stopper 8
Vacuum capping device for 144 holders 12 with completed empty capping
8 to the discharge conveyor 48.
ing. (Vacuum stopper) Next, a vacuum stopper 8 based on FIG.
To explain, the vacuum tapping device 8 includes a fixed frame
Vacuum chamber disposed above the mounting surface 51a
52, and on the upper surface of the vacuum chamber 52.
It has a casing 53 connected integrally. Vacuum chamber
The member 52 and the casing 53 are
It is connected to the upper end of a rod 54 penetrated through the mounting surface 51a.
And a cylinder mechanism 55 linked to this rod 54
Therefore, the rising end position shown in FIG. 6 and the falling end position shown in FIG.
It is designed to be raised and lowered. And the cylinder mechanism
The vacuum chamber 5 is moved to the lower end position shown in FIG.
2 and the casing 53 are lowered, the vacuum chamber
The lower end opening 52a of the bush 52 is placed on the placement surface 51a.
Thus, the inside of the vacuum chamber 52 is sealed.
You. On the other hand, a vacuum chamber is
The member 52 and the casing 53 are at the rising end positions shown in FIG.
The second pushing mechanism 39 when the
On the mounting surface 51a located directly below the vacuum chamber 52
In addition, 144 holders 12 (syringe
2) is supplied. The vacuum chamber 52
Via the flexible hose 56 and the flow path switching valve 57
It will be connected to either the vacuum pump 58 or the atmosphere
Swelling. Thereby, the sealed state shown in FIG.
Negative pressure or air is selectively introduced into the empty chamber 52.
Can be Inside the vacuum chamber 52, there is a
A step 61 is provided, and the step 61 is provided above the plug holding means 61.
At the position, a stopper pin 62 and a gap pin 63 were attached.
An attachment member 64 is provided. Inner plug holding means 61 is a plate-shaped part
Each holder made of a material and supplied on the mounting surface 51a
Step (12) (injection cylinder 2) with a step that expands in diameter on the lower side
Through holes are drilled, and each through hole is
The holding portion 61A holds the stopper 3. Above through hole
Each holding portion 61 </ b> A has an inner diameter that is larger than an outer diameter of the inner plug 3.
Is slightly smaller, so that the inner plug 3 is
When the inner plug 3 is extruded into the inside, the inner plug 3 is
1A. The holding unit 6
The above-mentioned gap pin 63 is formed along the axial direction on the inner peripheral surface of 1A.
The inner guide groove 61a is formed. Further, the holding unit 6
1A, the stepped portion 61b and the tapered hole 6
1c are connected in series, and the tapered hole 61c
The centering of the mouth 2a is performed, and the step 61b
Presses and holds the upper surface of the injection cylinder 2. Book
In the embodiment, when the inside of the vacuum chamber 52 is evacuated,
The resulting atmospheric pressure in the syringe barrel 2 and the vacuum chamber 52
To the mouth 2a of the syringe barrel 2 due to the pressure difference from the vacuum pressure
The inserted inner stopper 35 is pushed out of the syringe barrel 2, and
The inner plug 35 is held by each holding portion 61A.
You. The inner plug holding means 61 is provided with the vacuum chamber 52 and the case.
A plurality of lifting and lowering locks
Is connected to the lower end of the arm 65. Of each lifting rod 65
The upper end is a plate-like support member 66 provided in the casing 53.
It is connected to. At the center of the support member 66, both
A rod cylinder mechanism 67 is provided.
The lower end of the pad 67a is positioned directly below the support member 68.
While contacting the center of the upper surface of the cylinder rod 67a.
Is in contact with the lower surface of the central part of the casing 53 from below.
Touching. On the other hand, it is positioned above the inner plug holding means 61.
Each holding member 61 is attached to the mounting member 64 to be placed.
The stopper pin 62 is located at a position immediately above the holding portion 61A.
And the gap pin 63 is attached vertically downward.
You. The lower end of the gap pin 63 is closer to the lower end of the stopper pin 62.
And a predetermined dimension below it. Mounting member 6
4 seals the vacuum chamber 52 and the casing 53
Attached to the lower end of a plurality of elevating rods 71 that are held and penetrated
The upper end of each of the lifting rods 71 is
It is connected to the material 68. At the center of the lower surface of the support member 68
Is a cylinder mechanism provided at the center of the upper surface of the vacuum chamber 52.
72 piston rods 72a are connected to each other.
As shown in FIG.
Contact the lower end of the cylinder rod 67a of the cylinder mechanism 67
Let me. In addition, both rod cylinder mechanism 67 and case
Both rod syringes
Damper mechanism 67 and inner plug holding means 6 moving up and down integrally therewith
A compression spring 73 is provided which constantly pushes the compression spring 1 downward. Sa
Further, the casing 53 is provided at a predetermined position of the support member 66.
A fixed guide rod 74 is inserted through this guide
A large diameter stopper 74a is formed at the lower end of the rod 74.
Has formed. The stopper 74a is supported from above by a supporting portion.
The lower end of the inner plug holding means 61 is
I try to regulate. And to the cylinder mechanism 72
Therefore, the support member 68 is moved up and down so that the stopper pin 62 and the
When the gap pin 63 is moved up and down, both rods
Cylinder mechanism 67 and inner plug holding means 6 integral therewith
1 can be raised and lowered. (Operation Step by Vacuum Plug 8) Next, as described above,
The operation by the constituted vacuum tapping device 8 will be described. Already on
In the above-described pre-process, filling of the chemical solution 4 and fitting of the inner stopper 3 are performed.
The mounted 144 holders 12 (syringe 2) are
With the chamber 52 at the upper end position,
The vacuum push-out mechanism 39 of the
It is supplied onto the mounting surface 51a located immediately below the chamber 52.
You. In this way, the paper is supplied onto the mounting surface 51a.
Therefore, 144 syringes 2 are held by the inner stopper holding means 61.
Immediately below the holding portion 61A, the stopper pin 62 and the gap pin 63
Position. After that, the cylinder mechanism 55
Therefore, the vacuum chamber 52 is moved down to the lower end position shown in FIG.
Since it is lowered, the inside of the vacuum chamber 52 is sealed. This
In the state of (1), the cylinder mechanisms 72 and 67
3. The stopper pin 62 and the inner stopper holding means 61 are respectively raised.
It is located at the rising end, and the flow path switching valve 57 is a vacuum chamber.
The inside of the chamber 52 is communicated with the atmosphere (see FIG. 9A).
See). When the vacuum chamber 52 is sealed, both rods
Activate the cylinder mechanism 67 to move the lifting rod 65 and the middle
The stopper holding means 61 is lowered, and
Of the syringe barrel 2 by the tapered hole 61c of the holding portion 61A.
While centering the portion 2a on the stopper pin 62,
The upper surface of the syringe 2 is pressed by the step 61b to hold the syringe 2
(See FIG. 9B). In this state,
By switching the flow path switching valve 57, the inside of the vacuum chamber 52 is evacuated.
The vacuum chamber 52 is communicated with a pump 58, for example.
A low vacuum state of about 300 Torr is set. Then this
The atmospheric pressure in the syringe barrel 2 and the vacuum in the vacuum chamber 52
A pressure difference occurs between the pressure and the pressure.
Holding part of the inner plug holding means 61
61A and is held by the holding portion 61A.
(FIG. 9B). Next, this state
Then, the inner plug holding hand is
The step 61 is raised to the original raised end position. This allows
Holding the inner plug 3 held by the stopper holding means 61 with respect to the syringe barrel 2
It is possible to raise the vacuum chamber
To make the inside of the syringe barrel 2 a vacuum by communicating with the
Can be. On the other hand, the inner plug 3 is integrated with the inner plug holding means 61.
By raising the lower end of the stopper pin 62
The inner pin 3 is fitted into the female screw portion 3b,
Is guided by the guide groove 61a of the inner plug holding means 61,
3 is projected below the lower surface of FIG.
(C)). Thus, a predetermined vacuum pressure is generated in the syringe 2.
Once introduced, both rod cylinder mechanisms 67 are activated
When the inner plug holding means 61 is lowered again,
When the mechanism 72 is operated, the gap pin 63 and the stopper pin 62
It is dropped together. And the step of the inner plug holding means 61
When 61b contacts the upper surface of the syringe barrel 2, the descent is stopped.
(FIG. 9 (d)), the gap
9 and the stopper pin 62 continue to be lowered (FIG. 9E).
reference). Then, the lowering of the gap pin 63 and the stopper pin 62 is continued.
By being continued, it was held by the inner plug holding means 61
The inner stopper 3 is inserted into the syringe barrel 2, in which case the inner stopper 3 is
The gap pin 63 is provided between the outer peripheral surface and the inner peripheral surface of the syringe barrel 2.
Since it is interposed and forms a gap in that part,
The small amount of air remaining in the vacuum chamber 52 should not escape into the vacuum chamber 52.
The inner stopper 3 can be inserted into the syringe 2 smoothly.
You. The step 61b of the inner plug holding means 61 is placed on the upper surface of the syringe barrel 2.
The contact stops the descent, but in this state,
The upper and lower ends of the Linda rod 67a are below the casing 53.
Surface and the upper surface of the support member 68,
The holding force for holding the shooting cylinder 2 is a double rod cylinder mechanism 67,
Only the own weight of the lifting rod 65 and the inner plug holding means 61 is applied.
Therefore, both rod cylinder mechanism 67 and casing 53
Necessary due to the resilience of the compression spring 73 provided between it and the lower surface
The holding force of the injection cylinder 2 having a large size is obtained. This
After that, the gap pin 63 and the stopper pin 62 become the lower end.
When the descent stops, the vacuum chamber 52 is
For example, a high vacuum state of about 10 to 50 Torr
Pneumatic pressure is applied to the syringe via a gap formed by the gap pin 63.
2 is introduced. Thus, a high vacuum is maintained in the syringe 2.
After the pressure is introduced, the cylinder mechanisms 67 and 72
And the stopper pin 62, the gap pin 63 and the inner plug holding means 6
1 is raised to the original raised end position.
Is separated from the inner plug 3 and the gap pin 63 is also
Is pulled out from between the housing 62 and the inner plug 3. This state
Then, the vacuum chamber 52 is raised by the cylinder mechanism 55.
It is raised to the end. And after this, the second extrusion
By the mechanism 39, a new 144 holders 12 (injection)
The cylinder 2) is supplied to a position immediately below the vacuum chamber 52.
On the other hand, 144 bottles that have already been vacuum-plugged as described above
Of the injection cylinder 2 from the position immediately below the vacuum chamber 52
It is discharged onto the conveyor 48. As described above, according to this embodiment,
According to the stoppering system 1, the injection device 2 by the filling device 5 is used.
From the filling of the drug solution 4 into the vacuum chamber 8 under vacuum
Mechanize the work up to refitting the inner stopper 3 to the syringe barrel 2
be able to. Therefore, the above series of work efficiency
It can be greatly improved. In the above embodiment,
The gap pin 63 is composed of a solid rod.
From a hollow rod. Inner plug holding means
61 has clamping means for clamping the inner plug 3
It may be. In this case, insert the inner stopper 3 into the mouth of the syringe 2
2a and press the upper end to the outside of the syringe barrel 2
Projecting, and hold the projecting part with the above clamping means
Can be done. In this case, insert the inner stopper 3
Atmospheric pressure in the firing tube 2 and vacuum pressure and pressure in the vacuum chamber 52
It is clear that the step of extruding with a difference can be omitted.
Is. Further, in the above embodiment, the inside of the vacuum chamber 52
After evacuating the syringe barrel 2 in
The stopper 3 is again fitted in the syringe 2,
And the inner stopper 3 is fitted into the syringe 2 again.
Supply the inert gas into the vacuum chamber between
And inserting a step of filling the inside of the syringe barrel 2 with an inert gas.
With the inside of the syringe 2 filled with the inert gas,
Alternatively, the inner plug 3 may be fitted again. Also,
In this embodiment, the inner stopper 3 is fitted to the syringe 2 as a container.
Has been described, but the mouth 2a is opened upward.
This embodiment can be applied to a general container.

As described above, according to the present invention, it is possible to obtain an effect that the working efficiency can be greatly improved as compared with the related art.

[Brief description of the drawings]

FIG. 1 is a plan view of a stoppering system showing an embodiment of the present invention.

FIG. 2 is a sectional view of a main part taken along line II-II in FIG.

FIG. 3 is a perspective view showing a main part of FIG. 2 for easy understanding;

FIG. 4 is a view showing a process when the inner stopper 3 is fitted to the injection cylinder 2 by the stopper mechanism 14.

FIG. 5 is an enlarged view of a main part of FIG. 1;

FIG. 6 is a front view of FIG. 5;

FIG. 7 is an enlarged view of a main part of FIG. 6;

FIG. 8 is a sectional view of a main part along a line VIII-VIII in FIG. 1;

FIG. 9 is a view showing an operation process by the vacuum tapping device shown in FIG. 8;

[Description of sign]

DESCRIPTION OF SYMBOLS 1 Plugging system 2 Syringe (container) 2a mouth 3 Inner plug 5 Filling device 6 Plugging device 7 Grouping device 8 Vacuum plugging device

──────────────────────────────────────────────────続 き Continuation of the front page (56) References JP-A-2-28064 (JP, A) JP-A-58-19267 (JP, A) JP-A-59-28973 (JP, A) JP-A-57-28973 93060 (JP, A) JP-A-6-285166 (JP, A) JP-A-6-56196 (JP, A) JP-B-42-25996 (JP, B1) (58) Fields investigated (Int. Cl. ⁷ , DB name) A61J 1/05 A61M 5/24 B67B 1/04

Claims (1)

(57) [Claims] 1. A filling device for filling a filling liquid into a container having an open mouth, a plugging device for fitting an inner plug into a mouth of the container filled by the filling device, and a plugging device. A grouping device for grouping a predetermined number of containers fitted with stoppers, and an inner plug once removed from the mouth of the containers grouped by the above grouping device under a vacuum state in a vacuum chamber, and the container is again inserted into the mouth of the container. A plugging system comprising: a vacuum plugging device for fitting a plug.