JP3227692B2 - Dialysis equipment disinfection method - Google Patents

Dialysis equipment disinfection method

Info

Publication number
JP3227692B2
JP3227692B2 JP03500195A JP3500195A JP3227692B2 JP 3227692 B2 JP3227692 B2 JP 3227692B2 JP 03500195 A JP03500195 A JP 03500195A JP 3500195 A JP3500195 A JP 3500195A JP 3227692 B2 JP3227692 B2 JP 3227692B2
Authority
JP
Japan
Prior art keywords
aqueous solution
dialysis
sodium hypochlorite
peracetic acid
dialyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP03500195A
Other languages
Japanese (ja)
Other versions
JPH08224299A (en
Inventor
利明 増田
縁 桝田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nipro Corp
Original Assignee
Nipro Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nipro Corp filed Critical Nipro Corp
Priority to JP03500195A priority Critical patent/JP3227692B2/en
Publication of JPH08224299A publication Critical patent/JPH08224299A/en
Application granted granted Critical
Publication of JP3227692B2 publication Critical patent/JP3227692B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【0001】[0001]

【産業上の利用分野】本発明は透析装置の消毒方法に関
し、さらに詳しくは透析終了後の透析機器配管内を次亜
塩素酸ナトリウム水溶液と過酢酸水溶液とを別個に順次
使用する透析装置の消毒方法に関する。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for disinfecting a dialysis apparatus, and more particularly to a method for disinfecting a dialysis apparatus in which a sodium hypochlorite aqueous solution and a peracetic acid aqueous solution are used separately and sequentially in a dialysis equipment pipe after dialysis. About the method.

【0002】[0002]

【従来の技術】従来透析装置の透析液として重炭酸イオ
ンを含有する透析液やブドウ糖含有透析液等種々の透析
液が使用されているが、透析回数が増加するにつれて透
析機器配管内に炭酸カルシウム等の沈澱物が堆積した
り、エンドトキシン等の毒性物質が増加したりする問題
があった。かかる透析機器配管内の沈澱物や毒性物質を
除去する方法として次亜塩素酸ナトリウム水溶液あるい
は酢酸により配管内を洗浄する手段が行われている。し
かしながら、次亜塩素酸ナトリウム水溶液では配管内に
堆積した炭酸カルシウムを除去することが困難である
し、酢酸は炭酸カルシウムを除去するが、そのためには
配管を腐食する程高い濃度を使用しなければならず夫々
単独で使用する際には問題があった。それ故にこれらの
化学物質を混合して使用した洗浄剤、例えば次亜塩素酸
ナトリウムとエチレンジアミン四酢酸とを界面活性剤で
混合した洗浄剤があるが、pHが5以下になると塩素ガス
が発生したり、有機物が存在すると通常の20〜100 倍の
有効塩素量を有する洗浄剤を使用しなければ十分に消毒
が行われない問題があった。
2. Description of the Related Art Conventionally, various dialysates such as bicarbonate-containing dialysate and glucose-containing dialysate have been used as a dialysate for a dialysis device. However, there is a problem that a precipitate such as the above deposits and toxic substances such as endotoxin increase. As a method for removing precipitates and toxic substances in the dialysis equipment piping, means for washing the piping with an aqueous solution of sodium hypochlorite or acetic acid is used. However, it is difficult to remove calcium carbonate deposited in the piping with an aqueous solution of sodium hypochlorite, and acetic acid removes calcium carbonate.For this purpose, it is necessary to use a concentration high enough to corrode the piping. However, there was a problem when each was used alone. Therefore, there is a detergent used by mixing these chemical substances, for example, a detergent obtained by mixing sodium hypochlorite and ethylenediaminetetraacetic acid with a surfactant, but when the pH becomes 5 or less, chlorine gas is generated. In addition, when organic substances are present, there is a problem that the disinfection is not sufficiently performed unless a cleaning agent having an effective chlorine amount 20 to 100 times that of a normal cleaning agent is used.

【0003】[0003]

【発明が解決しょうとする課題】本発明者等はこれらの
課題を解決するために鋭意研究し、酸と酸素により配管
中の蛋白質、糖分、脂肪分を分解し配管からこれらの有
機物質を剥離できないかと考え、過酢酸水溶液を使用し
て透析後の透析機器配管の洗浄を行った。過酢酸水溶液
は配管中の化学物質と反応して消毒作用をする。過酢酸
は分解しても無害の水と酢酸になるため廃水処理も簡単
であり、pHが5以下でも有害ガスの発生がなく、ブドウ
球菌、芽胞菌、大腸菌、かび、ウイルスなどの広い範囲
に高い除菌効果を発揮する性質を有しているが、透析機
器配管の洗浄を繰り返していくと、配管の出口側に蛋白
質と思われる有機物質が沈着する問題が発生した。
DISCLOSURE OF THE INVENTION The present inventors have studied diligently to solve these problems, and decompose proteins, sugars and fats in pipes with acids and oxygen to separate these organic substances from the pipes. Considering the possibility, the dialysis equipment piping was washed after dialysis using an aqueous solution of peracetic acid. The aqueous solution of peracetic acid reacts with a chemical substance in the pipe to perform a disinfecting action. Even if peracetic acid is decomposed, it becomes harmless water and acetic acid, so wastewater treatment is easy. No harmful gas is generated even if the pH is 5 or less, and it can be used in a wide range of staphylococci, spores, Escherichia coli, mold, viruses, etc. Although it has the property of exhibiting a high sterilization effect, repeated washing of the dialysis equipment piping caused a problem that organic substances, which are considered to be proteins, were deposited on the outlet side of the piping.

【0004】[0004]

【課題を解決するための手段】本発明者等はかかる課題
を解決するために、種々検討した結果本発明に到達し
た。すなわち、本発明は透析液を使用して透析を行う透
析装置の透析機器配管内を洗浄する方法において、次亜
塩素酸ナトリウム濃度が100〜3,000ppmである次亜塩素
酸ナトリウム水溶液と過酢酸濃度が50〜1,000ppmである
過酢酸水溶液とを別個に順次使用して透析装置を消毒す
る方法である。また、本発明は前記透析装置の消毒方法
において、次亜塩素酸ナトリウム水溶液と過酢酸水溶液
とを交互に使用して洗浄する透析装置の消毒方法であ
る。更に、本発明は前記透析装置の消毒方法において、
透析液を使用して透析を行なった後、透析器を外して代
用円筒管を合着させた透析機器配管内を次亜塩素酸ナト
リウム水溶液または過酢酸水溶液で洗浄し、次いで代用
円筒管を外して再度透析器を設置して透析を行い、その
後透析器を外して代用円筒管を合着させた透析機器配管
内を前回の洗浄液と異なる次亜塩素酸ナトリウム水溶液
または過酢酸水溶液で洗浄する透析装置の消毒方法であ
る。
Means for Solving the Problems The present inventors have conducted various studies in order to solve the above problems, and have reached the present invention. That is, the present invention provides a method for cleaning dialysis device in a pipe of a dialysis device which performs dialysis using dialysate, hypophosphorous
A method of disinfecting a dialysis device by using a sodium hypochlorite aqueous solution having a sodium chlorate concentration of 100 to 3,000 ppm and a peracetic acid aqueous solution having a peracetic acid concentration of 50 to 1,000 ppm separately and sequentially. is there. The present invention also relates to a method for disinfecting a dialysis device, wherein the method for disinfection is performed by alternately using an aqueous solution of sodium hypochlorite and an aqueous solution of peracetic acid. Furthermore, the present invention relates to the method for disinfecting the dialysis device,
After performing dialysis using the dialysate, the dialyzer is removed, and the inside of the dialysis equipment piping to which the substitute cylindrical tube is attached is washed with an aqueous solution of sodium hypochlorite or an aqueous solution of peracetic acid, and then the substitute cylindrical tube is removed. Dialyzer to perform dialysis again, and then remove the dialyzer, and wash the inside of the dialysis equipment pipe with the substitute cylindrical tube attached with a sodium hypochlorite aqueous solution or peracetic acid aqueous solution different from the previous washing solution This is the method of disinfecting the device.

【0005】図1は透析器を使用した透析液制御システ
ムの一例を示す説明図であって、図中1は透析器、2は
第1ダイアフラム室、3はビスカスポンプ、4は新鮮透
析液入口、5は処理済透析液出口、7は第2ダイアフラ
ム室を示す。図1は特公平3-5490号公報に記載の透析液
制御システムを使用した透析装置の説明図であって、透
析を行う透析器1は半透膜によって血液室と透析液室に
区画されており、透析器の血液室には動脈からの血液が
血液入口10から入り、半透膜を介して血液処理された血
液は血液出口17から静脈に返血される。一方、透析液は
新鮮透析液が透析器1に入り、透析処理後の処理済透析
液は透析器1から排出されて可動隔膜で3室に区分され
たダイアフラム室に入る。ダイアフラム室は2個並設さ
れており、透析器1に交互に新鮮透析液を供給するとと
もに、処理済透析液も交互に排出するようになってい
る。
FIG. 1 is an explanatory view showing an example of a dialysate control system using a dialyzer, wherein 1 is a dialyzer, 2 is a first diaphragm chamber, 3 is a viscous pump, and 4 is a fresh dialysate inlet. Reference numeral 5 denotes a treated dialysate outlet, and reference numeral 7 denotes a second diaphragm chamber. FIG. 1 is an explanatory view of a dialysis device using a dialysate control system described in Japanese Patent Publication No. 3-5490, in which a dialyzer 1 for performing dialysis is divided into a blood chamber and a dialysate chamber by a semi-permeable membrane. The blood from the artery enters the blood chamber of the dialyzer through the blood inlet 10, and the blood processed through the semi-permeable membrane is returned to the vein through the blood outlet 17. On the other hand, as for the dialysate, fresh dialysate enters the dialyzer 1, and the processed dialysate after the dialysis treatment is discharged from the dialyzer 1 and enters the diaphragm chamber divided into three chambers by the movable diaphragm. Two diaphragm chambers are arranged side by side, so that fresh dialysate is alternately supplied to the dialyzer 1 and treated dialysate is alternately discharged.

【0006】第1ダイアフラム室2は2枚の可動隔膜6
によって、内部を供給室、可動容積室および回収室の3
室に区画されている。供給室に導入された新鮮透析液は
制御弁11、13および15を開にし、制御弁12、14および16
を閉にした密閉回路を通って透析器1の透析液室に供給
され、透析器1の透析液室から排出された新鮮透析液は
透析器1で浄化され、浄化された処理済透析液は第1ダ
イアフラム室2の回収室に回収されるようになってい
る。第1ダイアフラム室2の回収室に収容された処理済
透析液は制御弁12を開にすることによって、第1ダイア
フラム室2の供給室に供給される新鮮透析液が回収室の
処理済透析液を押し出し、処理済透析液は出口5から外
部に廃液される。第1ダイアフラム室2内の可変容積室
には、シリコンオイル等の液体が密封されており、一方
の可動隔膜6が移動した際には、ビスカスポンプ3によ
ってシリコンオイル量を変動させ他方の可動隔膜6も変
異できるようになっている。密閉回路の各制御弁の開閉
はマイクロコンピュ−タ−を含む制御装置によって制御
されており、各制御弁の開閉操作、すなわち制御弁14お
よび16を開にし、制御弁13および15を閉にすることによ
って、新鮮透析液は他の第2ダイアフラム室7の供給室
に供給され、透析器1で浄化された処理済透析液は第2
ダイアフラム室7の回収室に回収されるようになってい
る。第2ダイアフラム室7の操作は第1ダイアフラム室
2と同じである。
The first diaphragm chamber 2 has two movable diaphragms 6.
The interior is divided into a supply chamber, a movable volume chamber, and a collection chamber.
It is divided into rooms. Fresh dialysate introduced into the supply chamber opens control valves 11, 13 and 15, and control valves 12, 14 and 16
The fresh dialysate supplied to the dialysate chamber of the dialyzer 1 through a closed circuit that is closed and discharged from the dialysate chamber of the dialyzer 1 is purified by the dialyzer 1, and the purified dialysate that has been purified is It is to be collected in the collection chamber of the first diaphragm chamber 2. The treated dialysate stored in the collection chamber of the first diaphragm chamber 2 opens the control valve 12 so that the fresh dialysate supplied to the supply chamber of the first diaphragm chamber 2 is treated with the processed dialysate in the collection chamber. , And the treated dialysate is discharged to the outside from the outlet 5. A liquid such as silicon oil is sealed in the variable volume chamber in the first diaphragm chamber 2. When one movable diaphragm 6 moves, the amount of silicon oil is changed by the viscous pump 3 to cause the other movable diaphragm to move. 6 can also be mutated. The opening and closing of each control valve of the closed circuit is controlled by a control device including a microcomputer, and the opening and closing operation of each control valve, that is, the control valves 14 and 16 are opened and the control valves 13 and 15 are closed. Thereby, the fresh dialysate is supplied to the supply chamber of the other second diaphragm chamber 7, and the treated dialysate purified by the dialyzer 1 is supplied to the second dialyser 1.
It is collected in the collection chamber of the diaphragm chamber 7. The operation of the second diaphragm chamber 7 is the same as that of the first diaphragm chamber 2.

【0007】透析終了後、透析器1を取り外し、代わり
に透析機器配管と同じ内径のパイプ構造をした代用円筒
管(図示せず)を合着させる。次いで、次亜塩素酸ナト
リウム水溶液を新鮮透析液入口4から給液ポンプ8によ
って供給し、次亜塩素酸ナトリウム水溶液は制御弁11、
13および15が開になり、制御弁12、14および16が閉にな
っている密閉回路を通って第1ダイアフラム室2の供給
室に収容される。供給室に収容された次亜塩素酸ナトリ
ウム水溶液は第1密閉回路の配管内を通って、配管内を
消毒して第1ダイアフラム室2の回収室に収容される。
回収室に収容された消毒済次亜塩素酸ナトリウム水溶液
制御弁12を開にすることによって、第1ダイアフラ
ム室2の供給室に供給された新鮮次亜塩素酸ナトリウム
水溶液に押し出され、処理済透析液出口5から外部に廃
される。第2ダイアフラム室7およびその密閉回路の
配管は第1ダイアフラム室2の消毒と同様で制御弁14お
よび16を開にし、制御弁13および15を閉にすることによ
って行われる。消毒後、水で透析機器配管内を洗浄して
消毒液を配管内に残留させないようにする。新鮮次亜塩
素酸ナトリウム水溶液の濃度は 100〜3000ppm 、特に 3
00〜1000ppm が好ましい。透析終了後の洗浄の順序は、
例えば代用円筒管を合着させた回路を先ず水洗し、次い
で次亜塩素酸ナトリウム水溶液で配管内を消毒する。そ
の後再び水洗して透析機器配管内の洗浄操作は終了す
る。
After completion of the dialysis, the dialyzer 1 is removed, and a substitute cylindrical tube (not shown) having a pipe structure having the same inner diameter as the dialysis device piping is attached instead. Next, an aqueous solution of sodium hypochlorite is supplied from a fresh dialysate inlet 4 by a feed pump 8, and the aqueous solution of sodium hypochlorite is supplied to the control valve 11,
13 and 15 are opened and the control valves 12, 14 and 16 are accommodated in the supply chamber of the first diaphragm chamber 2 through a closed circuit which is closed. The aqueous sodium hypochlorite solution stored in the supply chamber passes through the pipe of the first closed circuit, disinfects the pipe, and is stored in the collection chamber of the first diaphragm chamber 2.
The disinfected aqueous sodium hypochlorite solution stored in the recovery chamber is pushed out to the fresh aqueous sodium hypochlorite aqueous solution supplied to the supply chamber of the first diaphragm chamber 2 by opening the control valve 12 and treated. is the waste to the outside from the dialysis fluid outlet 5. The piping of the second diaphragm chamber 7 and the closed circuit thereof is performed by opening the control valves 14 and 16 and closing the control valves 13 and 15 in the same manner as the disinfection of the first diaphragm chamber 2. After disinfection, wash the dialysis equipment piping with water so that the disinfectant does not remain in the piping. The concentration of the aqueous solution of fresh sodium hypochlorite is 100-3000 ppm, especially 3
Preferably from 100 to 1000 ppm. The order of washing after completion of dialysis is
For example, the circuit to which the substitute cylindrical tube is attached is first washed with water, and then the inside of the piping is disinfected with an aqueous solution of sodium hypochlorite. Thereafter, washing is performed again with water, and the washing operation in the dialysis equipment piping is completed.

【0008】次に、代用円筒管を取り除いて透析装置に
透析器1を連結し、前述と同じ方法で再び透析操作を行
う。透析終了後透析器1を取り外し代用円筒管を合着さ
せ水洗する。次いで過酢酸水溶液を前記と同じ操作で密
閉回路の配管内を通過させて洗浄する。過酢酸水溶液の
濃度は50〜1000ppm 、特に 100〜300ppmが好ましい。過
酢酸水溶液による消毒も次亜塩素酸ナトリウム水溶液の
ときと同様に消毒前後に水洗する。この実施例では透析
機器配管内の洗浄を次亜塩素酸ナトリウム水溶液で洗浄
後、透析操作を行い、次いで過酢酸水溶液で洗浄する操
作を繰り返す方法、すなわち次亜塩素酸ナトリウム水溶
による消毒と過酢酸水溶液による消毒を交互に行う
消毒方法について説明したが、透析終了後次亜塩素酸ナ
トリウム水溶液による消毒を行い、次いで透析操作を行
い再度次亜塩素酸ナトリウム水溶液で行う消毒、すなわ
ち次亜塩素酸ナトリウム水溶液による消毒を2回繰り返
した後、過酢酸水溶液による消毒を行ってもよい。ま
た、この実施例では配管内を次亜塩素酸ナトリウム水溶
液で消毒した後に、過酢酸水溶液による消毒をすること
について説明したが、この順序が逆の過酢酸水溶液によ
る消毒をした後に、次亜塩素酸ナトリウム水溶液で消毒
してもよい。以下実施例で本発明の一例を説明する。
Next, the substitute cylindrical tube is removed, the dialyzer 1 is connected to the dialyzer, and the dialysis operation is performed again in the same manner as described above. After completion of the dialysis, the dialyzer 1 is removed, the substitute cylindrical tube is attached, and the tube is washed with water. Next, the peracetic acid aqueous solution is passed through the pipe of the closed circuit by the same operation as above to be washed. The concentration of the aqueous solution of peracetic acid is preferably 50 to 1000 ppm, particularly preferably 100 to 300 ppm. Disinfection with an aqueous solution of peracetic acid is also carried out before and after disinfection, as in the case of an aqueous solution of sodium hypochlorite. In this embodiment, the inside of the dialysis equipment piping is washed with an aqueous solution of sodium hypochlorite, then a dialysis operation is performed, and then the operation of washing with an aqueous solution of peracetic acid is repeated, that is, disinfection with an aqueous solution of sodium hypochlorite and peracetic acid. It has been described sterilizing method of performing disinfection with an aqueous solution alternately, dialysis after completion perform disinfection sodium hypochlorite solution and then disinfected performed again sodium hypochlorite solution was dialyzed operation, i.e. hypochlorite After repeating the disinfection with a sodium aqueous solution twice, the disinfection with a peracetic acid aqueous solution may be performed. Further, in this embodiment, it has been described that the inside of the pipe is disinfected with an aqueous solution of sodium hypochlorite and then disinfected with an aqueous solution of peracetic acid. It may be disinfected with an aqueous solution of sodium acid. Hereinafter, an example of the present invention will be described with reference to examples.

【0009】[0009]

【実施例1】図1の透析装置で透析操作を行った後、透
析器を取り除きその後に回路の配管と同じ内径の代用円
筒管を合着させた。その後透析機器配管内を30分間水洗
した。次いで過酢酸水溶液(濃度150ppm)を透析機器配
管内に30分間洗浄して配管内を消毒した。その後、45分
間水洗して消毒液を透析機器配管内から取り除いた。次
に、代用円筒管を配管内から取り除いて透析器を合着さ
せ、再度透析操作を行った。透析終了後透析器を取り除
き、代わりに代用円筒管を合着させ透析機器配管内を30
分間水洗した。その後透析機器配管内を次亜塩素酸ナト
リウム水溶液(濃度800ppm)で30分間洗浄した。消毒終
了後45分間水洗し消毒液を除去した。この操作を1週間
繰り返した後に排液付近の配管内壁を観察したところ、
蛋白質も炭酸カルシウムの付着もみられなかった。
Example 1 After the dialysis operation was performed with the dialysis apparatus shown in FIG. 1, the dialyzer was removed, and then a substitute cylindrical tube having the same inner diameter as the piping of the circuit was joined. Thereafter, the inside of the dialysis equipment piping was washed with water for 30 minutes. Next, an aqueous solution of peracetic acid (concentration: 150 ppm) was washed in the dialysis equipment piping for 30 minutes to disinfect the piping. Thereafter, the rinsing solution was washed for 45 minutes to remove the disinfectant from the dialysis equipment piping. Next, the substitute cylindrical tube was removed from the pipe, the dialyzer was attached, and the dialysis operation was performed again. After completion of dialysis, remove the dialyzer and attach a substitute cylindrical tube instead.
For a minute. Thereafter, the inside of the dialysis equipment pipe was washed with an aqueous solution of sodium hypochlorite (concentration 800 ppm) for 30 minutes. After the disinfection was completed, washing was performed for 45 minutes to remove the disinfecting solution. After repeating this operation for one week, the inner wall of the pipe near the drainage was observed.
Neither protein nor calcium carbonate adhered.

【0010】[0010]

【比較例1】実施例1において、過酢酸水溶液(濃度15
0ppm)で配管内を洗浄して消毒する操作のみを1週間繰
り返した。すなわち透析−水洗30分間−過酢酸水溶液に
よる消毒30分間−水洗45分間の一連の操作を1週間繰り
返した。この操作を1週間繰り返した後に排液付近の配
管内壁を観察したところ、蛋白質が付着しているのがみ
られた。
Comparative Example 1 In Example 1, an aqueous solution of peracetic acid (concentration 15
Only the operation of washing and disinfecting the piping with 0 ppm) was repeated for one week. That is, a series of operations of dialysis, washing with water for 30 minutes, disinfection with an aqueous solution of peracetic acid for 30 minutes, and washing with water for 45 minutes was repeated for one week. After repeating this operation for one week, the inner wall of the pipe near the drainage was observed, and it was found that the protein had adhered.

【0011】[0011]

【比較例2】実施例1において、次亜塩素酸ナトリウム
水溶液(濃度800ppm)で配管内を洗浄して消毒する操作
のみを1週間繰り返した。すなわち透析−水洗30分間−
次亜塩素酸ナトリウム水溶液による消毒30分間−水洗45
分間の一連の操作を1週間繰り返した。この操作を1週
間繰り返した後に排液付近の配管内壁を観察したところ
炭酸カルシウムの白いスケ−ルの付着がみられた。
Comparative Example 2 In Example 1, only the operation of cleaning and disinfecting the pipes with an aqueous solution of sodium hypochlorite (concentration: 800 ppm) was repeated for one week. That is, dialysis-washing for 30 minutes-
Disinfection with sodium hypochlorite aqueous solution for 30 minutes-Rinse with water 45
A series of operations for one minute was repeated for one week. After repeating this operation for one week, the inner wall of the pipe near the drainage was observed, and adhesion of a white scale of calcium carbonate was observed.

【0012】[0012]

【発明の効果】本願方法によって、透析終了後の透析機
器配管内を消毒・殺菌すると、配管内壁に炭酸カルシウ
ムや蛋白質の付着がない。従って炭酸カルシウムや蛋白
質が配管に付着することによる装置の異常が発生せず、
安全な透析を行うことができる。
According to the method of the present invention, when the inside of the dialysis equipment pipe is disinfected and sterilized after dialysis, calcium carbonate and protein do not adhere to the pipe inner wall. Therefore, there is no malfunction of the device due to calcium carbonate or protein adhering to the piping,
Safe dialysis can be performed.

【図面の簡単な説明】[Brief description of the drawings]

【図1】透析器を使用した透析液制御システムの一例を
示す説明図
FIG. 1 is an explanatory diagram showing an example of a dialysate control system using a dialyzer.

【符号の表示】[Display of sign]

1 透析器 2 第1ダイアフラム室 3 ビスカスポンプ 4 新鮮透析液入口 5 処理済透析液出口 7 第2ダイアフラム室 Reference Signs List 1 dialyzer 2 first diaphragm chamber 3 viscous pump 4 fresh dialysate inlet 5 treated dialysate outlet 7 second diaphragm chamber

Claims (3)

(57)【特許請求の範囲】(57) [Claims] 【請求項1】 透析液を使用して透析を行う透析装置の
透析機器配管内を洗浄する方法において、次亜塩素酸ナ
トリウム濃度が100〜3,000ppmである次亜塩素酸ナトリ
ウム水溶液と過酢酸濃度が50〜1,000ppmである過酢酸水
溶液とを別個に順次使用して透析装置を消毒する方法。
1. A method for cleaning dialysis device in a pipe of a dialysis device which performs dialysis using dialysate, hypochlorite Sanna
A method of disinfecting a dialysis device by separately and sequentially using an aqueous solution of sodium hypochlorite having a thorium concentration of 100 to 3,000 ppm and an aqueous solution of peracetic acid having a peracetic acid concentration of 50 to 1,000 ppm .
【請求項2】 次亜塩素酸ナトリウム水溶液と過酢酸水
溶液とを交互に使用して洗浄する請求項1記載の透析装
置の消毒方法。
2. The method for disinfection of a dialysis device according to claim 1, wherein the washing is performed by using an aqueous solution of sodium hypochlorite and an aqueous solution of peracetic acid alternately.
【請求項3】 透析液を使用して透析を行なった後、透
析器を外して代用円筒管を合着させた透析機器配管内を
次亜塩素酸ナトリウム水溶液または過酢酸水溶液で洗浄
し、次いで代用円筒管を外して再度透析器を設置して透
析を行い、その後透析器を外して代用円筒管を合着させ
た透析機器配管内を前回の洗浄液と異なる次亜塩素酸ナ
トリウム水溶液または過酢酸水溶液で洗浄する請求項1
または2記載の透析装置の消毒方法。
3. After performing dialysis using the dialysate, the dialyzer is removed, and the inside of the dialysis equipment pipe to which the substitute cylindrical tube is attached is washed with an aqueous solution of sodium hypochlorite or an aqueous solution of peracetic acid. Remove the substitute cylindrical tube and install the dialyzer again to perform dialysis.After that, remove the dialyzer and attach the substitute cylindrical tube to the dialysis device piping, and use a different sodium hypochlorite aqueous solution or peracetic acid from the previous washing solution. Washing with an aqueous solution
Or the method for disinfecting a dialysis device according to item 2.
JP03500195A 1995-02-23 1995-02-23 Dialysis equipment disinfection method Expired - Lifetime JP3227692B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP03500195A JP3227692B2 (en) 1995-02-23 1995-02-23 Dialysis equipment disinfection method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03500195A JP3227692B2 (en) 1995-02-23 1995-02-23 Dialysis equipment disinfection method

Publications (2)

Publication Number Publication Date
JPH08224299A JPH08224299A (en) 1996-09-03
JP3227692B2 true JP3227692B2 (en) 2001-11-12

Family

ID=12429884

Family Applications (1)

Application Number Title Priority Date Filing Date
JP03500195A Expired - Lifetime JP3227692B2 (en) 1995-02-23 1995-02-23 Dialysis equipment disinfection method

Country Status (1)

Country Link
JP (1) JP3227692B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011255917A (en) * 2010-06-08 2011-12-22 Daiwa Can Co Ltd Method for sterilizing container for aseptic filling

Also Published As

Publication number Publication date
JPH08224299A (en) 1996-09-03

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