JP3078209B2 - Sterilization cleaning method for artificial dialysis equipment - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for sterilizing and cleaning artificial dialysis equipment, and more particularly to a method for sterilizing and cleaning containers, tubes, filters, and equipment used in artificial dialysis. is there.

[0002]

2. Description of the Related Art Conventional sterilization and washing treatment of artificial dialysis equipment is carried out by bringing an aqueous solution of sodium hypochlorite or a surfactant into contact with containers, tubes, filters, equipment and the like used for artificial dialysis. ing. Since calcium carbonate adheres to the inner surface of such instruments during use and causes scale, it has to be washed with an acidic substance such as acetic acid every two to three days to remove the scale. . JP-A-7-39858 discloses an invention in which a chlorocyanuric acid-based compound is used for treating infectious waste generated in medical institutions and the like.

[0003]

In the case of using an aqueous solution of sodium hypochlorite or a surfactant in the sterilization and cleaning treatment of the equipment of the artificial dialysis apparatus, the pH of the treated chemical is usually in the range of 10 to 13 and is alkaline. As a result, calcium carbonate adheres to the inner surface of the dialysis instruments, and scale is generated. When discharging a waste liquid containing sodium hypochlorite, a surfactant or the like or a processing liquid containing an acidic substance such as acetic acid, a neutralization treatment is performed.

[0004]

Means for Solving the Problems The present inventors have improved the sterilizing and cleaning action on the equipment of the artificial dialysis apparatus, removed calcium carbonate adhering to the inner surface of the equipment, and did not require the neutralization treatment of the waste liquid. After careful examination of the method,
Di-chloro isocyanuric acid alkali artificial dialyzer instrumentation
It has been found that the intended purpose can be achieved by bringing an aqueous solution containing a metal salt into contact, and the present invention has been completed.

[0005] In the practice of the method of the present invention, the concentration of active chlorine is 0.00 depending on the degree of contamination of the containers, tubes, filters and equipment of the artificial dialysis equipment to be treated.
From 5 to 0.1%, preferably to be in the range of 0.01 to 0.04%, to adjust the concentration of the aqueous solution of di-chloro isocyanuric acid alkali metal salt. In order to bring the treatment liquid into contact with the containers, tubes, filters, and fixtures of the equipment for the artificial dialysis apparatus, any of the methods of circulation, immersion, wiping, and spraying is possible. The treatment is generally performed at room temperature, and the contact is performed in a range of several seconds to several hours depending on the degree of contamination. Dialysis apparatus instrumentation are di-chloro isocyanuric acid A
After being treated with an aqueous solution containing a rukari metal salt, it is washed with water.

[0006] As a typical implementation Suitable di-chloro isocyanuric acid alkali metal salts of the present invention, potassium di-sodium chloroacetate isocyanuric acid and dichloroisocyanuric acid. Application Benefits chloro isocyanuric acid and dichloroisocyanurate are compared to dichloroisocyanurate alkali metal salts, chlorine odor is strong, also like too time consuming to completely dissolve in water, the preparation of the treatment liquid is complicated.

[0007]

The present invention will now be described by way of Examples and Comparative Examples.
This will be specifically described. Example 1 and Comparative Example 1 280 g of sodium dichloroisocyanurate was dissolved in 700 liters of purified water, and p
A treatment solution having H6.5 and an active chlorine concentration of 250 ppm was prepared, and this was circulated in contact with used containers and tubes of artificial dialysis equipment for 6 hours. Then, purified water is flowed through the circulating line of the dialysis device, and the washing water is collected from the last part of the tube to be used as a specimen, and the viable bacteria (Kle) contained therein is sampled.
bsiella Pneumoniae) was determined. Also, for comparison, sodium hypochlorite 4400
g was dissolved in 700 liters of purified water to prepare a treatment solution having a pH of 12 and an active chlorine concentration of 500 ppm, and the same test as above was carried out using the solution to measure the viable cell count. These test results were as shown in Table 1.

[0008]

[Table 1]

Example 2 and Comparative Example 2 280 g of sodium dichloroisocyanurate was dissolved in 700 liters of purified water to prepare a treatment solution having a pH of 6.5 and an active chlorine concentration of 250 ppm, and this treatment solution was continuously used. The container and tube of the artificial dialysis equipment inside are circulated daily for 6 hours, and this treatment is performed continuously for 30 days. The state of calcium carbonate generated in the equipment is observed, and when the formation of scale is confirmed. Then, a cleaning treatment with acetic acid was immediately performed, and the frequency of occurrence was examined. For comparison, 4400 g of sodium hypochlorite was dissolved in 700 liters of purified water to prepare a treatment solution having a pH of 12 and an active chlorine concentration of 500 ppm, and the same test as above was performed using the treatment solution. The scale cleaning frequency due to development was examined.
These test results were as shown in Table 2.

[0010]

[Table 2]

Example 3 and Comparative Example 3 190 g of sodium dichloroisocyanurate was dissolved in 600 liters of purified water to prepare a treatment solution having a pH of 6.5 and an active chlorine concentration of 200 ppm. The containers and tubes of the dialysis equipment were immersed in contact for 6 hours. Next, the container and the tube were connected to a dialysis machine, purified water was flowed through the circulation line, and washing water was collected from the final portion of the tube to obtain a specimen, and Pseudomon as an indicator bacterium.
As aeruginosa bacteria were examined, and their sterilizing and cleaning effects were evaluated. For comparison, 6000 g of sodium hypochlorite was dissolved in 600 liters of purified water,
12.2, a treatment solution having an active chlorine concentration of 800 ppm was prepared, and the same test as described above was performed using this solution. The results of these tests were as shown in Table 3.

[0012]

[Table 3]

[0013]

Di-chloro isocyanuric acid alkali metal salt of use in the present invention exhibits, in comparison with sodium hypochlorite has a sufficient sterilizing power and detergency with active chlorine concentration of 1/2 or less, And the aqueous solution containing them has a pH of 6 to
7 is a weakly acidic to neutral, since the carbonate calcium U beam deposition artificial dialyzer instrumentation is readily soluble, the cleaning operation by the scale formation is reduced, also it is discharged without neutralization of the waste Such effects in implementation are remarkable.

Claims (2)

(57) [Claims] We claim: 1. artificial dialyzer instrumentation contacting an aqueous solution containing a di-chloro isocyanuric acid alkali metal salt, artificial
Removes calcium carbonate adhering to the inner surface of dialysis equipment
Sterilizing and washing process of the hemodialysis apparatus instrumentation, characterized in Rukoto is. 2. An artificial dialyzer instrumentation is contacted with an aqueous solution containing sodium di-chloro isocyanuric acid, dialysis
A method for sterilizing and cleaning artificial dialysis equipment, wherein calcium carbonate adhering to the inner surface of the equipment is removed .