JP3057295B2 - 心機能回復剤 - Google Patents

心機能回復剤

Info

Publication number
JP3057295B2
JP3057295B2 JP7507470A JP50747095A JP3057295B2 JP 3057295 B2 JP3057295 B2 JP 3057295B2 JP 7507470 A JP7507470 A JP 7507470A JP 50747095 A JP50747095 A JP 50747095A JP 3057295 B2 JP3057295 B2 JP 3057295B2
Authority
JP
Japan
Prior art keywords
present
group
agent
inosine
cardiac function
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP7507470A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO1995005832A1 (ja
Inventor
和夫 市原
弘臣 横山
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Factory Inc
Original Assignee
Otsuka Pharmaceutical Factory Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Factory Inc filed Critical Otsuka Pharmaceutical Factory Inc
Publication of JPWO1995005832A1 publication Critical patent/JPWO1995005832A1/ja
Application granted granted Critical
Publication of JP3057295B2 publication Critical patent/JP3057295B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP7507470A 1993-08-25 1994-08-19 心機能回復剤 Expired - Fee Related JP3057295B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5-210096 1993-08-25
JP21009693 1993-08-25
PCT/JP1994/001375 WO1995005832A1 (en) 1993-08-25 1994-08-19 Heart function restorative

Publications (2)

Publication Number Publication Date
JPWO1995005832A1 JPWO1995005832A1 (ja) 1995-10-05
JP3057295B2 true JP3057295B2 (ja) 2000-06-26

Family

ID=16583754

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7507470A Expired - Fee Related JP3057295B2 (ja) 1993-08-25 1994-08-19 心機能回復剤

Country Status (7)

Country Link
EP (1) EP0665016A4 (show.php)
JP (1) JP3057295B2 (show.php)
KR (1) KR960701639A (show.php)
CN (1) CN1113647A (show.php)
CA (1) CA2146242A1 (show.php)
TW (1) TW280772B (show.php)
WO (1) WO1995005832A1 (show.php)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732019B1 (fr) * 1995-03-24 1997-06-13 Flamel Tech Sa Spiropyrannes photochromiques, compositions et articles les contenant
JP2002500001A (ja) 1997-09-10 2002-01-08 ヴァイオン ファーマシューティカルズ、インコーポレーテッド 低下した毒性を有する遺伝子改変腫瘍標的化細菌
US6080849A (en) 1997-09-10 2000-06-27 Vion Pharmaceuticals, Inc. Genetically modified tumor-targeted bacteria with reduced virulence
JP5333970B2 (ja) 2007-03-20 2013-11-06 国立大学法人大阪大学 心筋梗塞の予防および／または治療薬
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1206341B (it) * 1984-02-16 1989-04-14 Crinos Industria Farmaco Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
ZA892928B (en) * 1988-04-25 1991-01-30 Pro Neuron Inc Pharmaceutical compositions containing deoxyribonucleosides for wound healing
JPH04242830A (ja) * 1991-01-08 1992-08-31 Brother Ind Ltd 故障診断装置
JP2714728B2 (ja) * 1991-07-01 1998-02-16 株式会社大塚製薬工場 腸粘膜萎縮抑制剤
IT1251160B (it) * 1991-08-07 1995-05-04 Bioresearch Spa Impiego di composti adenosinici nel trattamento dell'ischemia
JP3032053B2 (ja) * 1991-09-06 2000-04-10 日水製薬株式会社 ウリジン誘導体及びこれを含有する医薬

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
「冠動脈疾患−新しい診断・治療体系（日本臨床第４５巻・１９８７年増刊号）」（昭６２−１２−１０）、日本臨床社、第７２−７９頁
「医学大辞典（第１７版）」（平２−２−１）、南山堂、第９８０−９８１頁「心収縮」の項
Ｃｒａｄｉｏｖａｓｃｕｌａｒ Ｒｅｓｅａｒｃｈ，Ｖｏｌ．１７，ｐ．１４５−１５１（１９８３）
Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｐｈａｒｍａｃｏｌｏｇｙ，Ｖｏｌ．５７，ｐ．１７９−１８４（１９７９）

Also Published As

Publication number Publication date
CN1113647A (zh) 1995-12-20
WO1995005832A1 (en) 1995-03-02
EP0665016A1 (en) 1995-08-02
TW280772B (show.php) 1996-07-11
KR960701639A (ko) 1996-03-28
CA2146242A1 (en) 1995-03-02
EP0665016A4 (en) 1998-01-21

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees