JP2835710B2 - Denture cleaning composition - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to a denture cleaning composition used for cleaning and sterilizing dentures.

[0002]

2. Description of the Related Art It is known that dentures are often contaminated not only with food residues and coloring matters, but also with microbes derived from oral microbes during wearing. In particular, denture plaque, which is said to be mainly composed of fungi, mainly Candida albicans, in recent years often adheres to the denture base mucosal surface.

[0003] In order to remove these stains, conventionally, as a denture cleaning agent, an oxygen-based material such as sodium peroxide, sodium perborate, sodium persulfate, potassium hydrogen persulfate (OXONE manufactured by DuPont) has been used. Bleaching agents; chlorine bleaching agents such as sodium hypochlorite, sodium dichlorisocyanurate, sodium trichloroisocyanurate; enzymes such as alkaline protease, dextranase, mutanase, inulase, glucanase, lipase, papain; and acids And a composition containing an active ingredient such as alkali and the like.

[0004] In addition, various relatively inactive components such as a lubricant such as magnesium stearate, a bulking agent, a binder, a coloring agent, a dye, and peppermint oil, l-menthol are added to a composition containing these active components. Thus, a denture cleaner having a desired size and density or a desired color and flavor was obtained by appropriately adding a fragrance or the like.

[0005] Further, in order to obtain a foaming detergent for enhancing the physical cleaning effect, a carbon dioxide-generating mixture comprising a carbonate compound and an acid is further added to the composition containing the above-mentioned active ingredient. I was Known carbonate compounds are alkali metal carbonates or bicarbonates, for example sodium, potassium, lithium or rubidium carbonates or bicarbonates. On the other hand, the acid component is generally citric acid, tartaric acid, succinic acid, fumaric acid, or a mixture thereof, but may be another acid containing sodium or potassium acid phosphate, or a mixture thereof. It has been known.

In order to further impart a surface tension lowering function to this foaming detergent, sodium lauryl sulfoacetate, sodium lauryl sulfate, and other anionic and nonionic surfactants are added to the active oxygen compound. It is also known that it is added in an amount of about 0.8 to about 2% by weight (JP-A-51-38415).

[0007] Dirt attached to the denture and the denture base is bleached, disinfected, sterilized by the combined action of the active ingredient of the denture cleaner, the physical action of the foaming agent, and the surface tension lowering function of the surfactant. It is possible to wash with effects such as protein decomposition and carbohydrate decomposition.

[0008]

However, it takes a long time to completely clean dirt from a denture, and at least one of them is required.
He had to do dentures all day and night.

[0009] Further, in the case where a denture cleaning agent formed of a denture cleaning composition containing a certain surfactant among the above surfactants is dissolved in an aqueous solvent, the oxygen-based bleaching agent is used as an active ingredient. In this case, the washing solution became cloudy, and it was not possible to realize the effect while visually observing the washing, and it was difficult to understand when the washing was completed.

[0010] Further, when a denture cleanser molded with a denture cleansing composition containing a certain surfactant is dissolved in an aqueous solvent, the denture cleanser immediately floats on the water surface, and foaming or the like occurs. In some cases, the detergency may be reduced due to the physical action of the resin.

According to the present invention, even when a denture cleaning composition containing an oxygen bleaching agent is dissolved in an aqueous solvent, the cleaning solution does not become cloudy when a denture cleaning agent molded from the composition is dissolved in an aqueous solvent. An object of the present invention is to obtain a denture cleaning composition that makes it easy to understand when cleaning has been completed because the effect can be realized while visually observing the cleaning.

Further, the present invention provides a method of dissolving a denture cleaner formed from the composition in an aqueous solvent without causing the denture cleaner to immediately float on the surface of water and causing physical effects such as foaming. It is an object of the present invention to obtain a denture cleaning composition which can sufficiently receive the composition without deteriorating the detergency.

Further, the present invention provides a composition containing a foaming component, in which the foaming time can be adjusted when the molded denture cleaner is dissolved in an aqueous solvent, and the foaming time can be adjusted appropriately. Is intended to obtain a denture cleaning composition capable of setting a cleaning time.

[0014]

SUMMARY OF THE INVENTION The denture cleaning composition of the present invention is characterized by containing sodium lauryl sulfoacetate, sodium dodecylbenzene sulfate and an oxygen bleach.

In the denture cleaning composition of the present invention, the sodium lauryl sulfoacetate is 0.01% by weight to 10% by weight, the sodium dodecylbenzene sulfate is 0.01% by weight to 10% by weight, and the oxygen bleaching agent is It is preferable to contain 10% by weight to 50% by weight, respectively.

[0016]

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in more detail. Sodium lauryl sulfoacetate used in the denture cleaning composition of the present invention contains 0.0
It is preferable that the content is 1% by weight to 10% by weight, more preferably 0.1% by weight to 5% by weight. When the amount is less than 0.01% by weight, there is no detergency, and when the amount exceeds 10% by weight, there is a problem in tableting properties.

[0017] The sodium dodecylbenzene sulfate used in the denture cleaning composition of the present invention is preferably incorporated in the denture cleaning composition in an amount of 0.01 to 10% by weight, more preferably 0.1% by weight. -5% by weight. When the amount is less than 0.01% by weight, there is no detergency, and when the amount exceeds 10% by weight, there is a problem in tableting properties.

Further, in the denture cleaning composition of the present invention, 1 part by weight to 10 parts by weight of sodium dodecylbenzene sulfate is added to 100 parts by weight of the above sodium lauryl sulfoacetate.
When 2,000 parts by weight is contained, when the foaming detergent is used, the denture detergent is less likely to float on the surface of water, and a sufficient washing effect by physical action such as foaming can be obtained. It is added in an amount of from 200 to 200 parts by weight, most preferably from 10 to 50 parts by weight.

Examples of the oxygen bleaching agent used in the denture cleaning composition of the present invention include sodium peroxide, sodium perborate, sodium persulfate, and potassium hydrogen hydrogen persulfate (OXONE manufactured by DuPont). An oxygen-based bleach can be used, and is preferably incorporated in the denture cleaning composition in an amount of 10% by weight to 50% by weight, more preferably 20% by weight to 40% by weight. When the amount is less than 10% by weight, the deodorizing effect is reduced. Conversely, if the compounding amount exceeds 50% by weight, the stability of the molded denture cleaner tends to decrease.

The denture cleaning composition of the present invention further comprises an alkaline protease,
Enzymes such as dextranase, mutanase, inulase, glucanase, lipase and papain can be incorporated.

Further, various relatively inactive ingredients which are usually used, for example, lubricants such as magnesium stearate, extenders, binders, coloring agents, dyes, peppermint oil, perfumes such as l-menthol, etc. granular,
In order to obtain an arbitrary dosage form such as granules and tablets, it can be appropriately added.

[0022]

【Example】

(Example 1) Using a denture cleaning composition having the following composition, a foaming denture cleaning agent (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0% by weight Sodium bicarbonate 40.0% by weight Potassium hydrogen persulfate 25.0% by weight Sodium perborate 5.0% by weight Polyethylene glycol 3.5% by weight Sodium lauryl sulfoacetate 3.0% by weight % Sodium dodecylbenzene sulfate 0.5% by weight

(Example 2) Using a denture cleaning composition having the following composition, a foaming denture cleaner (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0% by weight Sodium bicarbonate 40.0% by weight Potassium hydrogen persulfate 25.0% by weight Sodium perborate 5.0% by weight Polyethylene glycol 3.0% by weight Sodium lauryl sulfoacetate 3.0% by weight % Sodium dodecylbenzene sulfate 1.0% by weight

Example 3 Using a denture cleaning composition having the following composition, a foaming denture cleaning agent (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0% by weight Sodium bicarbonate 40.0% by weight Potassium hydrogen persulfate 25.0% by weight Sodium perborate 5.0% by weight Polyethylene glycol 2.5% by weight Sodium lauryl sulfoacetate 3.0% by weight % Sodium dodecylbenzene sulfate 1.5% by weight

Example 4 Using a denture cleaning composition having the following composition, an effervescent denture cleaner (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0 wt% Sodium bicarbonate 40.0 wt% Potassium hydrogen persulfate 25.0 wt% Sodium perborate 5.0 wt% Polyethylene glycol 2.0 wt% Sodium lauryl sulfoacetate 3.0 wt% % Sodium dodecylbenzene sulfate 2.0% by weight

(Example 5) Using a denture cleaning composition having the following composition, a foaming denture cleaner (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0% by weight Sodium hydrogen carbonate 40.0% by weight Potassium hydrogen persulfate 25.0% by weight Sodium perborate 5.0% by weight Polyethylene glycol 2.5% by weight Sodium lauryl sulfoacetate 4.0% by weight % Sodium dodecylbenzene sulfate 0.5% by weight

(Example 6) Using a denture cleaning composition having the following composition, a foaming denture cleaner (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0% by weight Sodium hydrogen carbonate 40.0% by weight Potassium hydrogen persulfate 25.0% by weight Sodium perborate 5.0% by weight Polyethylene glycol 2.0% by weight Sodium lauryl sulfoacetate 4.0% by weight % Sodium dodecylbenzene sulfate 1.0% by weight

(Example 7) Using a denture cleaning composition having the following composition, a foaming denture cleaner (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0 wt% Sodium bicarbonate 40.0 wt% Potassium hydrogen persulfate 25.0 wt% Sodium perborate 5.0 wt% Polyethylene glycol 1.5 wt% Sodium lauryl sulfoacetate 4.0 wt% % Sodium dodecylbenzene sulfate 1.5% by weight

(Comparative Example 1) Using a denture cleaning composition having the following composition, an effervescent denture cleaner (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0% by weight Sodium hydrogen carbonate 40.0% by weight Potassium hydrogen persulfate 25.0% by weight Sodium perborate 5.0% by weight Polyethylene glycol 4.0% by weight Sodium lauryl sulfoacetate 3.0% by weight %

Comparative Example 2 Using a denture cleaning composition having the following composition, an effervescent denture detergent (3 g) containing an oxygen bleach was obtained. Citric anhydride 23.0% by weight Sodium bicarbonate 40.0% by weight Potassium hydrogen persulfate 25.0% by weight Sodium perborate 5.0% by weight Polyethylene glycol 3.0% by weight Sodium lauryl sulfoacetate 4.0% by weight % (Tablet Disintegration Test) One tablet of each of the denture cleaners obtained in the above Examples and Comparative Examples was placed in a stainless steel container having a mesh of about 5 mm mesh, and this was placed in a 40 ° C hot water (2
00 ml), and the time when the tablet completely disintegrated was measured. Table 1 shows the results. (Oil-and-fat washing test) A slide glass was immersed in a solution consisting of JIS (household washing, artificial stain) for 10 seconds to attach pseudo stain, and then dried to obtain a test plate.

Then, each of the denture cleaners obtained in the above Examples and Comparative Examples was placed in a beaker containing 150 ml of water at 25 ° C., and was immediately inserted so that the test plate was vertically set. After 15 minutes, each plate was taken out, and the cleaning effect was visually evaluated. Table 1 shows the results. (Tablet Floating Test) One denture cleaning agent obtained in each of the above Examples and Comparative Examples was poured into hot water (200 ml) at 40 ° C., and the time when the tablets floated was measured. Table 1 shows the results. (Clarity test of solution) One tablet of each denture cleaner obtained in the above Examples and Comparative Examples was poured into water (200 ml) at 25 ° C, and the turbidity of the solution after tablet disintegration was visually evaluated. Table 1 shows the results.

[0033]

[Table 1]

[0034]

According to the present invention, even a denture cleaning composition containing an oxygen bleach is formed from the composition by containing sodium lauryl sulfoacetate and sodium dodecylbenzene sulfate. When the denture cleaner was dissolved in an aqueous solvent, the cleaning solution was not turbid,
Since the effect can be realized while visually observing the cleaning, it becomes easy to understand when the cleaning is completed.

Further, according to the present invention, when the denture cleaner formed from the composition is dissolved in an aqueous solvent, the denture cleaner does not immediately float on the water surface regardless of the dosage form. In addition, physical effects due to foaming and the like can be sufficiently received, and the detergency does not decrease.

Continuation of the front page (72) Inventor Tetsushi Nishioka 9 Tanakagami Okubocho, Sakyo-ku, Kyoto-shi, Kyoto (72) Inventor Yuji Miyazato 8-6-12-405 Motoyama Minamicho, Higashinada-ku, Kobe-shi, Hyogo (56) References Special JP-A-51-38415 (JP, A) JP-A-2-22217 (JP, A) (58) Fields investigated (Int. Cl. ⁶ , DB name) A61K 7/30

Claims (2)

(57) [Claims] 1. A denture cleaning composition comprising sodium lauryl sulfoacetate, sodium dodecylbenzene sulfate and an oxygen bleach. 2. The method according to claim 1, wherein sodium lauryl sulfoacetate is added to 0.02%.
1% to 10% by weight, 0.01% to 10% by weight of sodium dodecylbenzene sulfate, 10% by weight of oxygen bleach
A composition for cleaning dentures, comprising from 50% by weight to 50% by weight.