JP2515181Y2 - Reagent device - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial field of application] The present invention relates to a reagent device, and more particularly to a reagent device capable of easily replacing a reagent that is frequently used and used in a large amount.

[Conventional technology and its problems]

As is well known, not all reagents are used at the same frequency and in the same amount in multiple types of reagents used in an automatic blood analyzer, and the use of each reagent depends on the measurement item. At present, the frequency and the amount used differ greatly.

By the way, in many conventional automatic analyzers, a liquid level sensor is inserted into a reagent bottle, and the amount of each reagent is monitored and replaced.

However, in the automatic analyzer equipped with the liquid level sensor, the mechanism becomes very complicated and the cost of the device increases, and there is also a structure in which the reagent holder cannot be replaced while the automatic analyzer is in operation. In many cases, there is a problem that the replacement work of such a reagent bottle is complicated.

The present invention was devised in view of the current situation, and its purpose is to easily replace a reagent bottle even while the automatic analyzer is in operation, and to use a liquid level sensor or other liquid It is an object of the present invention to provide a reagent device which has a simple structure and allows convenient handling because the remaining amount can be easily visually checked without confirming the amount.

[Means for solving the problem]

In order to achieve the above object, in a reagent device according to the present invention, a reagent for sucking a required amount of a reagent from a reagent container containing a reagent corresponding to a measurement item and dispensing it to another container A reagent container of the reagent holder, which comprises a pipette, a stirring device for stirring a sample in a container in which a reagent is dispensed by the reagent pipette, and a reagent holder holding a plurality of the reagent containers. The holding hole for holding is arranged along the rotation trajectory of the reagent pipette, and the washing trough for the reagent pipette and the washing trough for the stirring device are agitated with the reagent pipette at the end of the reagent holder. It is characterized in that it is arranged along each rotation locus of the device.

[Action]

In the reagent device according to the present invention, the amount of the reagent in the reagent bottle can be easily visually recognized from the top of the reagent bottle, and when replacing the reagent bottle, the reagent bottle is lifted up. A new reagent bottle can be replaced with a new one by simply replacing it with a reagent holder, and the cleaning trough for the reagent pipette and the cleaning trough for the agitator can be positioned only by setting the reagent holder in the specified position. Can be done accurately with.

〔Example〕

Hereinafter, the present invention will be described in detail with reference to an embodiment shown in the accompanying drawings.

As shown in FIG. 1, the reagent apparatus A according to this embodiment has a plurality of reaction vessels 1 arranged in a loop, a drive unit (not shown) for transferring the reaction vessels 1, and a reagent distribution unit. At the pouring position, the required amount of reagent is aspirated and the reagent is transferred to the reaction container 1 described above.
Reagent pipette P to be dispensed into the container, a stirring device K which rotates together with the reagent pipette P to stir the mixed solution of serum and reagent in the reaction container 1, and a plurality of types (in the illustrated embodiment, 4).
Reagent bottles 2A, 2B, 2C and 2D containing reagents
And a cleaning trough 4 and 5 attached to the tip of the reagent holder 3.

The drive device for transferring the reaction container 1 is one for intermittently transferring the plurality of reaction containers 1 to a predetermined position one pitch at a time while heating the reaction containers 1 to a predetermined temperature, and a known pulse motor is used.

The reagent pipette P has an arm whose one end is rotatably supported by a shaft, a pi pellet which is disposed at the other end of the arm, and a pipette which is communicatively connected to the pi pellet so that a required amount of liquid can be supplied. It is composed of a pump that sucks and discharges it to the reaction container 1, and each drive device (not shown) that controls the rotation of the arm from each predetermined position to another position at predetermined timing and controls elevation of each arm at each position. ing.

This reagent pipette metering system fills the wicking system with water, sucks and measures the reagent and water in a separated state via air, discharges only the reagent, and then passes the washing water from the inside. Clean the inside of the pipette. At the time of this washing, the reagent pipette P is set right above the washing trough 4, and the reagent attached to the outer surface of the reagent pipette P is washed at the same position.

Although not shown, the stirring device K is transferred with the rotation of the arm of the reagent pipette P, and when the reagent pipette P dispenses the reagent into the reaction container 1, It is configured to stir the sample in the reaction container 1 that has been transferred by one container upstream from the dispensing position with a stirring rod or bubbles, and then the stirring rod or bubble pipe (not shown) The sample set on the washing trough 5 and attached to the outer surface of the stirring rod or the bubble pipe is washed at the same position.

The reagent bottles 2A, 2B, 2C, 2D and the reagent holder 3 are preferably formed of a material desirable for visually recognizing the reagent amount from the outside, for example, a transparent tempered glass material, a resin material, or the like.

The reagent holder 3 is formed in a substantially crescent-shaped plane, and the respective holding holes 6 into which the reagent bottles 2A, 2B, 2C and 2D are inserted and held have the axis thereof as the rotation trajectory of the reagent pipette P. It is formed at predetermined intervals along v.

Considering the replacement workability of the reagent bottles 2A, 2B, 2C and 2D, the reagent holder 3 is preferably arranged on the front side of the automatic analyzer.

Next, the operation of the reagent device A configured as above will be described.

The type of the reagent to be dispensed into the reaction container 1 which reaches the reagent dispensing position is input in advance to a control device (not shown), and the reagent pipette P is set to each reagent bottle based on a command from the control device. The reagent bottle 2 containing the corresponding reagent is selected from 2A, 2B, 2C, or 2D, and a required amount of the reagent is sucked from the reagent bottle 2 and then the sucked reagent is dispensed into the reaction container 1. Then, after this work is completed, the reagent pipette P is transferred to directly above the cleaning trough 4, and the reagent pipette P is cleaned at this position. At this time, the stirring rod or bubble pipe that stirred the mixed liquid in the other reaction vessel 1 is
The reagent pipette P is transferred to just above the cleaning trough 5, and the reagent pipette P is cleaned at this position.

On the other hand, when the reagent amount of any of the reagent bottles 2A, 2B, 2C or 2D is reduced and the reagent bottle 2 needs to be replaced, while the reagent pipette P dispenses the reagent into the reaction container 1,
Alternatively, while the cleaning work is being performed, the reagent bottles 2A, 2
One of B, 2C and 2D can be lifted up and replaced by a simple operation of simply inserting a new reagent bottle 2A, 2B, 2C or 2D into the reagent holder 3.

[Effect of device]

As described above, the present invention makes it possible to easily visually recognize the reagent amount in the reagent bottle from above the reagent bottle without confirming the liquid amount with a liquid level sensor or the like, and to replace the reagent bottle. In this case, the reagent bottle can be replaced by a simple operation such as lifting the reagent bottle up and inserting a new reagent bottle into the reagent holder, and at the same time, the washing trough for the reagent pipette and the washing trough for the agitator can be replaced. Positioning is also effective in that the reagent holder can be accurately set only by setting it at a predetermined position.

[Brief description of drawings]

FIG. 1 is an explanatory plan view showing a schematic configuration of a reagent device according to an embodiment of the present invention. [Explanation of Codes] A ... Reagent device, K ... Stirring device P ... Reagent pipette, 1 ... Reaction container 2A, 2B, 2C, 2D ... Reagent container 3 ... Reagent holder v ... Rotation locus of reagent pipette

Claims (1)

(57) [Scope of utility model registration request] 1. A reagent pipette for sucking a required amount of a reagent from a reagent container containing a reagent corresponding to a measurement item and dispensing the reagent to another container, and a container into which the reagent is dispensed by the reagent pipette. And a reagent holder for holding a plurality of the reagent containers, and the holding hole for holding the reagent container of the reagent holder has a rotation path of the reagent pipette. The cleaning trough for the reagent pipette and the cleaning trough for the stirring device are arranged along the respective rotation loci of the reagent pipette and the stirring device at the end of the reagent holder. Characteristic reagent device.