JP2025515346A5 - - Google Patents
Info
- Publication number
- JP2025515346A5 JP2025515346A5 JP2024563505A JP2024563505A JP2025515346A5 JP 2025515346 A5 JP2025515346 A5 JP 2025515346A5 JP 2024563505 A JP2024563505 A JP 2024563505A JP 2024563505 A JP2024563505 A JP 2024563505A JP 2025515346 A5 JP2025515346 A5 JP 2025515346A5
- Authority
- JP
- Japan
- Prior art keywords
- bont
- muscle
- unit dose
- dose
- unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2206361.4 | 2022-04-29 | ||
| GBGB2206361.4A GB202206361D0 (en) | 2022-04-29 | 2022-04-29 | Treatment of a facial dystonia |
| PCT/GB2023/050746 WO2023209327A1 (en) | 2022-04-29 | 2023-03-23 | Bont/a for use in treating a facial dystonia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025515346A JP2025515346A (ja) | 2025-05-14 |
| JP2025515346A5 true JP2025515346A5 (enExample) | 2026-03-30 |
Family
ID=81943823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024563505A Pending JP2025515346A (ja) | 2022-04-29 | 2023-03-23 | 顔面ジストニアを治療する用途のBoNT/A |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250213662A1 (enExample) |
| EP (1) | EP4514824A1 (enExample) |
| JP (1) | JP2025515346A (enExample) |
| KR (1) | KR20250004870A (enExample) |
| CN (1) | CN119095868A (enExample) |
| AU (1) | AU2023262229A1 (enExample) |
| CA (1) | CA3245925A1 (enExample) |
| GB (1) | GB202206361D0 (enExample) |
| WO (1) | WO2023209327A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2023471835A1 (en) * | 2023-11-01 | 2026-04-30 | Ipsen Biopharm Limited | Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| DE102004043009A1 (de) | 2004-09-06 | 2006-03-23 | Toxogen Gmbh | Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen |
| DE102005019302A1 (de) | 2005-04-26 | 2006-11-16 | Toxogen Gmbh | Carrier zum Targeting von Nervenzellen |
| DK2154151T3 (da) | 2005-09-19 | 2011-09-05 | Allergan Inc | Clostridiumtoksinaktiverbare clostridiumtoksiner |
| WO2010120766A1 (en) | 2009-04-14 | 2010-10-21 | Mcw Research Foundation, Inc. | Engineered botulinum neurotoxin |
| US8853360B2 (en) | 2010-06-23 | 2014-10-07 | Wisconsin Alumni Research Foundation | Engineered botulinum neurotoxin C1 with selective substrate specificity |
| EP2524963B1 (en) | 2011-05-19 | 2018-10-31 | Ipsen Bioinnovation Limited | Methods for the manufacture of proteolytically processed polypeptides |
| MX359480B (es) | 2012-05-30 | 2018-09-28 | President And Fellows Of Harvard College Star | Neurotoxina botulínica diseñada. |
| JP6156954B2 (ja) | 2012-11-21 | 2017-07-05 | イプセン バイオイノベーション リミテッド | タンパク分解性にプロセシングされたポリペプチドの製造方法 |
| RU2746736C2 (ru) | 2015-03-26 | 2021-04-20 | Президент Энд Феллоуз Оф Гарвард Колледж | Сконструированный ботулинический нейротоксин |
| GB201607901D0 (en) | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
| EP3263710A1 (en) * | 2016-07-01 | 2018-01-03 | Ipsen Biopharm Limited | Production of activated clostridial neurotoxins |
| EP3481852B1 (en) | 2016-07-08 | 2022-12-07 | Children's Medical Center Corporation | A novel botulinum neurotoxin and its derivatives |
| TWI810228B (zh) * | 2017-12-20 | 2023-08-01 | 英商艾普森生物製藥有限公司 | 自主神經系統障礙之治療 |
| GB202003813D0 (en) * | 2020-03-16 | 2020-04-29 | Ipsen Biopharm Ltd | Treatment of upper facial lines |
| CA3228712A1 (en) * | 2021-09-23 | 2023-03-30 | Nicolae GRIGORE | Modified bont/a for use in the treatment of a disorder affecting an eyelid muscle of a subject |
-
2022
- 2022-04-29 GB GBGB2206361.4A patent/GB202206361D0/en not_active Ceased
-
2023
- 2023-03-23 KR KR1020247039346A patent/KR20250004870A/ko active Pending
- 2023-03-23 CA CA3245925A patent/CA3245925A1/en active Pending
- 2023-03-23 JP JP2024563505A patent/JP2025515346A/ja active Pending
- 2023-03-23 CN CN202380036925.9A patent/CN119095868A/zh active Pending
- 2023-03-23 WO PCT/GB2023/050746 patent/WO2023209327A1/en not_active Ceased
- 2023-03-23 EP EP23715585.8A patent/EP4514824A1/en active Pending
- 2023-03-23 AU AU2023262229A patent/AU2023262229A1/en active Pending
- 2023-03-23 US US18/851,469 patent/US20250213662A1/en active Pending
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