JP2025515346A5 - - Google Patents

Info

Publication number
JP2025515346A5
JP2025515346A5 JP2024563505A JP2024563505A JP2025515346A5 JP 2025515346 A5 JP2025515346 A5 JP 2025515346A5 JP 2024563505 A JP2024563505 A JP 2024563505A JP 2024563505 A JP2024563505 A JP 2024563505A JP 2025515346 A5 JP2025515346 A5 JP 2025515346A5
Authority
JP
Japan
Prior art keywords
bont
muscle
unit dose
dose
unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024563505A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025515346A (ja
Filing date
Publication date
Priority claimed from GBGB2206361.4A external-priority patent/GB202206361D0/en
Application filed filed Critical
Publication of JP2025515346A publication Critical patent/JP2025515346A/ja
Publication of JP2025515346A5 publication Critical patent/JP2025515346A5/ja
Pending legal-status Critical Current

Links

JP2024563505A 2022-04-29 2023-03-23 顔面ジストニアを治療する用途のBoNT/A Pending JP2025515346A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2206361.4 2022-04-29
GBGB2206361.4A GB202206361D0 (en) 2022-04-29 2022-04-29 Treatment of a facial dystonia
PCT/GB2023/050746 WO2023209327A1 (en) 2022-04-29 2023-03-23 Bont/a for use in treating a facial dystonia

Publications (2)

Publication Number Publication Date
JP2025515346A JP2025515346A (ja) 2025-05-14
JP2025515346A5 true JP2025515346A5 (enExample) 2026-03-30

Family

ID=81943823

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024563505A Pending JP2025515346A (ja) 2022-04-29 2023-03-23 顔面ジストニアを治療する用途のBoNT/A

Country Status (9)

Country Link
US (1) US20250213662A1 (enExample)
EP (1) EP4514824A1 (enExample)
JP (1) JP2025515346A (enExample)
KR (1) KR20250004870A (enExample)
CN (1) CN119095868A (enExample)
AU (1) AU2023262229A1 (enExample)
CA (1) CA3245925A1 (enExample)
GB (1) GB202206361D0 (enExample)
WO (1) WO2023209327A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023471835A1 (en) * 2023-11-01 2026-04-30 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE102004043009A1 (de) 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen
DE102005019302A1 (de) 2005-04-26 2006-11-16 Toxogen Gmbh Carrier zum Targeting von Nervenzellen
DK2154151T3 (da) 2005-09-19 2011-09-05 Allergan Inc Clostridiumtoksinaktiverbare clostridiumtoksiner
WO2010120766A1 (en) 2009-04-14 2010-10-21 Mcw Research Foundation, Inc. Engineered botulinum neurotoxin
US8853360B2 (en) 2010-06-23 2014-10-07 Wisconsin Alumni Research Foundation Engineered botulinum neurotoxin C1 with selective substrate specificity
EP2524963B1 (en) 2011-05-19 2018-10-31 Ipsen Bioinnovation Limited Methods for the manufacture of proteolytically processed polypeptides
MX359480B (es) 2012-05-30 2018-09-28 President And Fellows Of Harvard College Star Neurotoxina botulínica diseñada.
JP6156954B2 (ja) 2012-11-21 2017-07-05 イプセン バイオイノベーション リミテッド タンパク分解性にプロセシングされたポリペプチドの製造方法
RU2746736C2 (ru) 2015-03-26 2021-04-20 Президент Энд Феллоуз Оф Гарвард Колледж Сконструированный ботулинический нейротоксин
GB201607901D0 (en) 2016-05-05 2016-06-22 Ipsen Biopharm Ltd Chimeric neurotoxins
EP3263710A1 (en) * 2016-07-01 2018-01-03 Ipsen Biopharm Limited Production of activated clostridial neurotoxins
EP3481852B1 (en) 2016-07-08 2022-12-07 Children's Medical Center Corporation A novel botulinum neurotoxin and its derivatives
TWI810228B (zh) * 2017-12-20 2023-08-01 英商艾普森生物製藥有限公司 自主神經系統障礙之治療
GB202003813D0 (en) * 2020-03-16 2020-04-29 Ipsen Biopharm Ltd Treatment of upper facial lines
CA3228712A1 (en) * 2021-09-23 2023-03-30 Nicolae GRIGORE Modified bont/a for use in the treatment of a disorder affecting an eyelid muscle of a subject

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