JP2024540579A5 - - Google Patents

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Publication number
JP2024540579A5
JP2024540579A5 JP2024529771A JP2024529771A JP2024540579A5 JP 2024540579 A5 JP2024540579 A5 JP 2024540579A5 JP 2024529771 A JP2024529771 A JP 2024529771A JP 2024529771 A JP2024529771 A JP 2024529771A JP 2024540579 A5 JP2024540579 A5 JP 2024540579A5
Authority
JP
Japan
Prior art keywords
muscle
units
pain
clostridium neurotoxin
neurotoxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024529771A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540579A (ja
Filing date
Publication date
Priority claimed from GBGB2116774.7A external-priority patent/GB202116774D0/en
Priority claimed from GBGB2116795.2A external-priority patent/GB202116795D0/en
Priority claimed from GBGB2206359.8A external-priority patent/GB202206359D0/en
Application filed filed Critical
Priority claimed from PCT/GB2022/052957 external-priority patent/WO2023089343A1/en
Publication of JP2024540579A publication Critical patent/JP2024540579A/ja
Publication of JP2024540579A5 publication Critical patent/JP2024540579A5/ja
Pending legal-status Critical Current

Links

JP2024529771A 2021-11-22 2022-11-22 疼痛の治療 Pending JP2024540579A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB2116774.7 2021-11-22
GBGB2116774.7A GB202116774D0 (en) 2021-11-22 2021-11-22 Treatment of pain
GB2116795.2 2021-11-22
GBGB2116795.2A GB202116795D0 (en) 2021-11-22 2021-11-22 Treatment of visceral pain
GB2206359.8 2022-04-29
GBGB2206359.8A GB202206359D0 (en) 2022-04-29 2022-04-29 Treatment of pain
PCT/GB2022/052947 WO2023089338A1 (en) 2021-11-22 2022-11-21 Treatment of visceral pain
GBPCT/GB2022/052947 2022-11-21
PCT/GB2022/052957 WO2023089343A1 (en) 2021-11-22 2022-11-22 Treatment of pain

Publications (2)

Publication Number Publication Date
JP2024540579A JP2024540579A (ja) 2024-10-31
JP2024540579A5 true JP2024540579A5 (enExample) 2025-12-01

Family

ID=84370182

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024529771A Pending JP2024540579A (ja) 2021-11-22 2022-11-22 疼痛の治療

Country Status (7)

Country Link
US (2) US20260014237A1 (enExample)
EP (1) EP4436594A1 (enExample)
JP (1) JP2024540579A (enExample)
KR (1) KR20240116485A (enExample)
AU (1) AU2022392458A1 (enExample)
CA (1) CA3234608A1 (enExample)
WO (1) WO2023089343A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202214232D0 (en) 2022-09-28 2022-11-09 Ispen Biopharm Ltd Clostridial neurotoxins comprising an activating exogenous protease cleavage site
GB202214229D0 (en) 2022-09-28 2022-11-09 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an activating endosomal protease cleavage site
GB202307439D0 (en) * 2023-05-18 2023-07-05 Ipsen Biopharm Ltd Treatment of a headache disorder with botylinum neurotoxin a
GB202318884D0 (en) 2023-12-11 2024-01-24 Ipsen Biopharm Ltd Formulation

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE102004043009A1 (de) 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen
DE102005019302A1 (de) 2005-04-26 2006-11-16 Toxogen Gmbh Carrier zum Targeting von Nervenzellen
DK2154151T3 (da) 2005-09-19 2011-09-05 Allergan Inc Clostridiumtoksinaktiverbare clostridiumtoksiner
WO2010120766A1 (en) 2009-04-14 2010-10-21 Mcw Research Foundation, Inc. Engineered botulinum neurotoxin
US8853360B2 (en) 2010-06-23 2014-10-07 Wisconsin Alumni Research Foundation Engineered botulinum neurotoxin C1 with selective substrate specificity
EP2524963B1 (en) 2011-05-19 2018-10-31 Ipsen Bioinnovation Limited Methods for the manufacture of proteolytically processed polypeptides
MX359480B (es) 2012-05-30 2018-09-28 President And Fellows Of Harvard College Star Neurotoxina botulínica diseñada.
JP6156954B2 (ja) 2012-11-21 2017-07-05 イプセン バイオイノベーション リミテッド タンパク分解性にプロセシングされたポリペプチドの製造方法
RU2746736C2 (ru) 2015-03-26 2021-04-20 Президент Энд Феллоуз Оф Гарвард Колледж Сконструированный ботулинический нейротоксин
GB201607901D0 (en) 2016-05-05 2016-06-22 Ipsen Biopharm Ltd Chimeric neurotoxins
SG11201810210UA (en) * 2016-06-08 2018-12-28 Childrens Medical Center Engineered botulinum neurotoxins
EP3481852B1 (en) 2016-07-08 2022-12-07 Children's Medical Center Corporation A novel botulinum neurotoxin and its derivatives
BR112020006827A2 (pt) 2018-01-29 2020-10-06 Ipsen Biopharm Limited neurotoxinas botulínicas clivando snare não neuronal
KR20220054371A (ko) * 2019-08-30 2022-05-02 이온 바이오파마, 인크. 두통 치료에 사용하기 위한 신경독소 조성물
GB201914034D0 (en) * 2019-09-30 2019-11-13 Ipsen Biopharm Ltd Treatment of neurological disorders
TW202426039A (zh) * 2020-03-16 2024-07-01 英商艾普森生物製藥有限公司 肢體痙攣之治療
GB202104294D0 (en) * 2021-03-26 2021-05-12 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an exogenous activation loop
CN117396217A (zh) * 2021-03-30 2024-01-12 益普生生物制药有限公司 无催化活性的梭菌神经毒素用于疼痛和炎性疾病的治疗
JP2024513191A (ja) * 2021-03-30 2024-03-22 イプセン バイオファーム リミテッド 疼痛及び炎症性障害の処置

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