JP2025513337A - 心原性ショック前および心原性ショックの処置のためのイスタロキシムを含む静脈内注入製剤 - Google Patents

心原性ショック前および心原性ショックの処置のためのイスタロキシムを含む静脈内注入製剤 Download PDF

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Publication number
JP2025513337A
JP2025513337A JP2024561787A JP2024561787A JP2025513337A JP 2025513337 A JP2025513337 A JP 2025513337A JP 2024561787 A JP2024561787 A JP 2024561787A JP 2024561787 A JP2024561787 A JP 2024561787A JP 2025513337 A JP2025513337 A JP 2025513337A
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JP
Japan
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hours
pharmaceutical composition
individual
blood pressure
systolic
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Pending
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JP2024561787A
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English (en)
Japanese (ja)
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JP2025513337A5 (https=
Inventor
シモンソン，スティーヴン
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Windtree Therapeutics Inc
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Windtree Therapeutics Inc
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Publication of JP2025513337A publication Critical patent/JP2025513337A/ja
Publication of JP2025513337A5 publication Critical patent/JP2025513337A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2024561787A 2022-04-20 2023-04-18 心原性ショック前および心原性ショックの処置のためのイスタロキシムを含む静脈内注入製剤 Pending JP2025513337A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263332909P 2022-04-20 2022-04-20
US63/332,909 2022-04-20
PCT/US2023/018998 WO2023205183A1 (en) 2022-04-20 2023-04-18 Istaroxime-containing intravenous formulation for the treatment of pre-cardiogenic shock and cardiogenic shock

Publications (2)

Publication Number Publication Date
JP2025513337A true JP2025513337A (ja) 2025-04-24
JP2025513337A5 JP2025513337A5 (https=) 2026-04-24

Family

ID=86331896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024561787A Pending JP2025513337A (ja) 2022-04-20 2023-04-18 心原性ショック前および心原性ショックの処置のためのイスタロキシムを含む静脈内注入製剤

Country Status (9)

Country Link
EP (1) EP4511040A1 (https=)
JP (1) JP2025513337A (https=)
KR (1) KR20250005343A (https=)
CN (1) CN119156218A (https=)
AU (1) AU2023256547A1 (https=)
CA (1) CA3248625A1 (https=)
IL (1) IL316164A (https=)
MX (1) MX2024012948A (https=)
WO (1) WO2023205183A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025128432A1 (en) * 2023-12-11 2025-06-19 Windtree Therapeutics, Inc. Istaroxime and metabolite derivatives thereof for reducing the risk of acute myocardial arrhythmia

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1079807A (en) 1912-09-25 1913-11-25 Jonathan S Snyder Coat-closure.
NL95803C (https=) 1953-12-31 1900-01-01
US4534899A (en) 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US5846743A (en) 1995-02-22 1998-12-08 Brigham And Women's Hospital, Inc. Polyphoshoinositide binding peptides for intracellular drug delivery
US6007839A (en) 1996-02-16 1999-12-28 The Liposome Company, Inc. Preparation of pharmaceutical compositions containing etherlipid-containing multiple lipid liposomes
US5874268A (en) 1996-09-23 1999-02-23 Duke University Method of introducing exogenous compounds into cells by electroporation and apparatus for same
US6063400A (en) 1997-07-02 2000-05-16 Sdg, Inc. Targeted liposomal constructs for diagnostic and therapeutic uses
SE9704076D0 (sv) 1997-11-06 1997-11-06 Holdingbolaget Vid Goeteborgs Method for permeabilisation of cell structures and use thereof
US6589503B1 (en) 1998-06-20 2003-07-08 Washington University Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy
US20040151766A1 (en) 2003-01-30 2004-08-05 Monahan Sean D. Protein and peptide delivery to mammalian cells in vitro
WO2005063156A1 (en) 2003-12-22 2005-07-14 Shear/Kershman Laboratories, Inc. Oral peptide delivery system with improved bioavailability
JP3903061B2 (ja) 2003-12-24 2007-04-11 株式会社Ｌｔｔバイオファーマ 薬物を含有するナノ粒子およびその製造方法、ならびに当該ナノ粒子からなる非経口投与用製剤
WO2006014035A1 (en) 2004-08-06 2006-02-09 Biospectrum, Inc. Multiple layered liposome and preparation method thereof
WO2006044986A1 (en) 2004-10-18 2006-04-27 Nitto Denko Corporation Intracellular peptide delivery
CN101267805A (zh) 2005-07-27 2008-09-17 普洛体维生物治疗公司 制造脂质体的系统和方法
CN103315968B (zh) 2013-06-26 2015-04-01 中国生命药物治疗有限公司 一种注射用粉针剂及其制备方法
MX2021010483A (es) 2019-03-05 2021-10-01 Windtree Therapeutics Inc Formulacion intravenosa que contiene istaroxima para el tratamiento de insuficiencia cardiaca aguda (ahf).

Also Published As

Publication number Publication date
IL316164A (en) 2024-12-01
AU2023256547A1 (en) 2024-11-28
MX2024012948A (es) 2024-11-08
WO2023205183A1 (en) 2023-10-26
EP4511040A1 (en) 2025-02-26
CA3248625A1 (en) 2023-10-26
CN119156218A (zh) 2024-12-17
KR20250005343A (ko) 2025-01-09

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