JP2025512431A5 - - Google Patents

Info

Publication number
JP2025512431A5
JP2025512431A5 JP2024560536A JP2024560536A JP2025512431A5 JP 2025512431 A5 JP2025512431 A5 JP 2025512431A5 JP 2024560536 A JP2024560536 A JP 2024560536A JP 2024560536 A JP2024560536 A JP 2024560536A JP 2025512431 A5 JP2025512431 A5 JP 2025512431A5
Authority
JP
Japan
Prior art keywords
seq
sequence
tim
car
fusion protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024560536A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025512431A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/065619 external-priority patent/WO2023201221A1/en
Publication of JP2025512431A publication Critical patent/JP2025512431A/ja
Publication of JP2025512431A5 publication Critical patent/JP2025512431A5/ja
Pending legal-status Critical Current

Links

JP2024560536A 2022-04-11 2023-04-11 組換えtim-4タンパク質、キメラ抗原受容体(car)t細胞送達システム及びそれを作製し、使用する方法 Pending JP2025512431A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263329551P 2022-04-11 2022-04-11
US63/329,551 2022-04-11
PCT/US2023/065619 WO2023201221A1 (en) 2022-04-11 2023-04-11 Recombinant tim-4 protein, chimeric antigen receptor (car) t cell delivery system and methods of making and using same

Publications (2)

Publication Number Publication Date
JP2025512431A JP2025512431A (ja) 2025-04-17
JP2025512431A5 true JP2025512431A5 (enExample) 2026-04-16

Family

ID=88330365

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024560536A Pending JP2025512431A (ja) 2022-04-11 2023-04-11 組換えtim-4タンパク質、キメラ抗原受容体(car)t細胞送達システム及びそれを作製し、使用する方法

Country Status (8)

Country Link
US (1) US20240156868A1 (enExample)
EP (1) EP4508093A1 (enExample)
JP (1) JP2025512431A (enExample)
KR (1) KR20250005223A (enExample)
CN (1) CN119301159A (enExample)
AU (1) AU2023254190A1 (enExample)
CA (1) CA3247489A1 (enExample)
WO (1) WO2023201221A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240182540A1 (en) * 2022-11-16 2024-06-06 Duke University Chimeric apoptotic signal targeting lymphocytes (tim-4 castl) and methods of making and using same
WO2025184206A1 (en) * 2024-02-26 2025-09-04 Duke University Nkg2d bi-specific t cell engager and chimeric antigen receptor / t cell receptor cell delivery systems and methods of making and using same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0509139A (pt) * 2004-03-24 2007-08-28 Telos Fharmaceuticals Inc composição, e, método de estimulação de uma resposta imune em um indivìduo, de tratamento profilático de uma doença, de melhoramento de um sinal ou sintoma associado com uma doença, de alvejamento de um tumor, de inibição do crescimento de tumor, e de detecção de um tumor
WO2013188693A1 (en) * 2012-06-15 2013-12-19 Imaginab, Inc. Antigen binding constructs to cd3
CA3109139A1 (en) * 2018-08-30 2020-03-05 HCW Biologics, Inc. Methods of treating aging-related disorders
JP7868033B2 (ja) * 2020-08-14 2026-06-01 セロ・セラピューティクス・ホールディングス・インコーポレイテッド キメラtim受容体およびその使用
WO2022036287A1 (en) * 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Anti-cd72 chimeric receptors and uses thereof

Similar Documents

Publication Publication Date Title
Chao et al. Fine epitope mapping of anti-epidermal growth factor receptor antibodies through random mutagenesis and yeast surface display
CN112154157B (zh) 抗ror1抗体及其用途
CN114539411B (zh) 一种ror1抗体或其抗原结合片段
US8492520B2 (en) Binding epitopes for G250 antibody
US10919951B2 (en) Chimeric antigen receptor
JP2020517294A5 (enExample)
CN112074532B (zh) 结合非天然NKG2D受体的非天然NKG2D配体的修饰的α1-α2结构域
CN110770252A (zh) 抗p53抗体
CN118652334B (zh) 一种靶向钙粘蛋白17的纳米抗体及其应用
CN117402243A (zh) 抗Nectin-4抗体及其应用
CN114106177B (zh) Cd22抗体及其应用
JP6707660B2 (ja) 抗ポドカリキシン様タンパク質前駆体サブタイプ2モノクローナル抗体とその生成方法及び使用
WO2026007560A1 (zh) 一种靶向成纤维活化蛋白α的纳米抗体及其应用
JP2024512260A (ja) Vegfa結合分子
AU2021446021A1 (en) Anti-bcam antibody or antigen-binding fragment thereof
CN114437232A (zh) 一种细胞表面大分子定量展示系统及其制备方法和用途
JP2022504472A (ja) Her2結合四量体ポリペプチド
WO2024120526A1 (zh) 抗ilt4抗体及其制备方法和应用
CN110615841A (zh) 抗人cd47单克隆抗体及其应用
CN118667005A (zh) 抗pd-l1的纳米抗体及其用途
CN118667004A (zh) 抗pd-l1的高阻断活性纳米抗体及其应用
CN101591396B (zh) 一种抗erbB2人源抗体MIL-5及其应用
CN117700555B (zh) 抗cll1的纳米抗体及其相关应用
CN117510636B (zh) Gprc5d抗体及其应用
CN121426938A (zh) 一种特异性结合新型冠状病毒核衣壳蛋白的抗体或其抗原结合片段及其应用